Thursday, 6 July 2023

#GreenTea Speeds Up the Healing Process of #Tendinitis by Improving the Compaction of the Collagen Molecules, Scientists Show

Kyle J. Norton

Green tea may have a therapeutic and positive effect on the healing of tendinitis by protecting collagen stability and fibrous connective tissue, some scientists suggested.
Tendinitis is a condition characterized by inflammation of a tendon as a result of overuse, infection or rheumatic disease.

The condition mostly happens to people who have jobs involving repetitive movements. Some

Some researchers suggested that in order to prevent tendinitis, it is better to change activities, or rest and come back to it later.

Most cases of tendinitis can be successfully treated with rest, sometimes with physical therapy.

Intake medication may also have a profound effect on reducing pain. However, they may induce common and serious side effects, depending on the types of medicine.

Please make sure that you understand all the side effects if you are currently taking the medicine for relieving pain.

Most cases of tendinitis are recurrent if the thick fibrous cords that attach muscle to bone are continuously overused due to the occupation

The most common symptoms of tendinitis are pain, tenderness, and mild swelling often described as a dull ache in the affected location particularly, in the limb or joint.

Tendonitis should be treated according to the medical guideline. The untreated condition may cause some complications, including chronic pain in the affected area that may interfere with daily activity and reduce the quality of life. Some untreated tendonitis may cause pain to spread to other parts of the body.

Some patients with untreated tendonitis are also experiencing psychological problems, such as anxiety and depression due to constant pain.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.

According to the study of the effect of GT and/or glycine in the diet on tendinitis in Wistar rats, randomly divided into seven groups (G): control group (C); G1 and G4, tendinitis; G2 and G5, tendinitis supplied with GT; and G3 and G6, tendinitis supplied with GT and a glycine diet for 7 or 21 days, respectively, group with tendinitis treated with green tea demonstrated a significant effect in enhanced collagen stability through expression of hydroxyproline in compared to other groups.

Furthermore, GT and glycine alone treated groups showed increased activity of metalloproteinase-2 MMP-2 levels which has been associated with the healing process of the fibrous connective tissue in tendinitis patients.

Compared to control and non-GT treatment groups, the application of green tea or GT+ glycine group displayed statistical significance in the decreased muscle retardation.

After taking into account all co-founders, Dr. Vieira CP, the lead author said, " GT + a glycine diet has beneficial effects that aid in the recovery process of the tendon after tendinitis".

Interestingly, the study investigated the remodeling effects of green tea and glycine in the myotendinous junction (MTJ) of male Wistar rats with tendinitis, randomly divided into five groups: animals without tendinitis, and animals with tendinitis; animals with tendinitis supplied with green tea; animals with tendinitis supplied with a glycine diet; animals with tendinitis supplied with a green tea and glycine diet, a researcher found that all treatment groups exerted a profound effect in regulated the activity of metalloproteinases (MMP)-2 with function in remodeling the tendon after tendinitis, MMP-8 and -9 which are associated to remodeling tissue expression in the disease progression and induced the synthesis of type I collagen regulation by cell spreading, platelet-derived growth factor and interactions with collagen fibers.

Moreover, rats groups treated above application also demonstrated an increase of glycosaminoglycans, in stimulating the regenerative processes, while maintaining host cell characteristics and function and non-collagenous proteins in modulated the development of fine fibrils presented in collagen fibers of connective tissue

Additionally, the combination of green tea and glycine also modulated the inflammatory process through the stimulated production of anti-inflammatory factors and induced the synthesis of the elements, such as extracellular matrix involved in the post-lesion recovery of the tissue.

These results indicated that recovery from an injured tendon can be achieved by improving the compaction of the collagen molecules and inducing the assembly of early collagen fibers.


After taking into account all cofounders, researchers, and colleagues at the Anat Rec said, "Each region of the inflamed tendon can exhibit different responses during the treatment and therefore, modify its extracellular matrix components to facilitate recovery and repair".

The findings suggested that green tea may be considered a functional food for speeding up the healing of tendinitis.

However, intake of supplements for the treatment of tendinitis should be taken with exceptional care in the prevention of acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Green Tea and Glycine Modulate the Activity of Metalloproteinases and Collagen in the Tendinitis of the Myotendinous Junction of the Achilles Tendon by Vieira CP1, De Oliveira LP2, Da RĂ© Guerra F3, Marcondes MC2, Pimentel ER2. (PubMed)
(2) Green tea and glycine aid in the recovery of tendinitis of the Achilles tendon of rats by Vieira CP1, Guerra Fda R, de Oliveira LP, Almeida MS, Marcondes MC, Pimentell ER. (PubMed)

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