Green tea may have a potentially hepatoprotective effect in the prevention and treatment of liver disease, renowned institutes postulated.
Liver disease is a reduced function in toxin elimination of the liver as a result of damage or injury, caused by medication, or viral infection,...
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "excessive yin syndrome" or "yang vacuity syndrome" including weakened immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
According to the joint study led by the Zhejiang Hospital of Southern Medical University Guangzhou, in the review of the database of PubMed, CNKI, Wanfang, and Weipu databases, regular green tea drinking is associated with a significant reduction in the risk of liver disease, including hepatocellular carcinoma, liver steatosis, hepatitis, liver cirrhosis, and chronic liver disease.
Also, Green tea demonstrated a reduced risk of liver disease regardless of the race and geography of the patients residing such as Asian, American, and European subgroups.
Unfortunately, in a mouse model, different doses of GT fractions and EGCG and a single dose of lipopolysaccharide (LPS) combined with EGCG, administered for 5 days to mice suggested that mice fed with combining a single high dose of EGCG with a single dose of LPS showed to induce liver injury.
Repeat injection of EGCG in the group was also found to associate with mild liver injury, probably attributed to the adverse effect of lipopolysaccharide (LPS), the study insisted.
Epigallocatechin Gallate (EGCG) is one of the major and powerful antioxidants of green tea found to be the most effective cancer chemopreventive polyphenol in many studies posted in the medical literature. However, the single ingredients extract has also been found to induce hepatotoxicity and acute liver dysfunction on many occasions due to overdoses and long-term usage.
Additionally, the Baylor College of Medicine and Dalhousie University, Halifax reported, "(There is) a case of acute impending liver failure in an adolescent male using a weight-loss product containing green tea extract" and "acute liver toxicity observed in individuals consuming supplements containing green tea extract".
Taking all together, the conflict result of green tea in liver disease may be the result of study design, group selection, sample size, doses intake,........People with liver disease should talk to a specialist in herbal products before consuming.
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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
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Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) The effect of green tea intake on risk of liver disease: a meta-analysis by Yin X1, Yang J2, Li T3, Song L4, Han T5, Yang M1, Liao H1, He J1, Zhong X1.(PubMed)
(2) Effect of green tea and its polyphenols on mouse liver by Saleh IG1, Ali Z, Abe N, Wilson FD, Hamada FM, Abd-Ellah MF, Walker LA, Khan IA, Ashfaq MK. (PubMed)
(3) Green tea extract: a potential cause of acute liver failure by Patel SS1, Beer S, Kearney DL, Phillips G, Carter BA. (PubMed)
(4) Acute liver failure induced by green tea extracts: case report and review of the literature by Molinari M1, Watt KD, Kruszyna T, Nelson R, Walsh M, Huang WY, Nashan B, Peltekian K.(PubMed)
(5) Effect of epigallocatechin gallate on uncoupling protein 2 in acute liver injury by Mohammad H Jamal,1,* Hamad Ali,2 Ali Dashti,2 Jasim Al-Abbad,1 Husain Dashti,1 Chako Mathew,2 Waleed Al-Ali,3 Sami Asfar1(PubMed)
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