Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.
In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating protein, lipid, and cell damage.
Free radicals are highly reactive molecules with an unpaired electron on the outermost ring of the atom.
Due to its nature to become stable, free radicals readily donate or steal an electron from other molecules, leading to the chain of domino effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.
There are 3 main types of antioxidants found in nature, including
* Antioxidant enzymes produced by the host, including superoxide dismutase (SOD), glutathione peroxidase, glutathione reductase, and catalases.
* Antioxidants vitamins, that may be injected from dietary sources such as fruits and vegetables, including vitamins A, C, D, and E. Most antioxidant vitamins are considered free radical scavengers that gobble up free radicals before they can induce a cascade of damage.
* Antioxidant Phytochemicals found in the plant including second metabolites.
Antioxidants keep our bodies functioning properly by reducing the risk of diseases associated with oxidative stress.
In finding a natural ingredient for the prevention and treatment of chronic low-grade inflammatory diseases, scientists examined the antioxidant activity of Euphrasia rostkoviana Hayne (Eyebright).
Eyebright is one of the species of flowering plants, genus Euphrasia, belonging to the family Orobanchaceae, native to Europe.
The plant has been used in traditional and herbal medicine to treat eye infections and to relieve inflammation caused by colds, coughs, sinus infections, sore throats, and hay fever.
According to ABTS and DPPH decolorization assays, Fraction one isolated from the herbal medicine, dominated by a glycosylated caffeic acid derivative, exhibited the strongest antioxidant activity.
Furthermore, the most effective IC50 concentrations were found to be 11.88 microg/ml and 4.24 microg/ml, respectively, compared to the investigated standards.
Additionally, the fractions of flavonoid glycosides proved to have a similarly strong, but lower effect compared to fraction one.
Most importantly, the scavenging reaction of the two radical cations was depending on the IC50.
Taken together, eyebright may be considered an antioxidant remedy for the treatment of chronic low-grade inflammatory diseases, pending the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [Antioxidant activity of different phenolic fractions separated from Euphrasia rostkoviana Hayne].[Article in Hungarian] by Blazics B1, Alberti A, Kéry A. (PubMed)
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