Kyle J. Norton
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.
In other words, diabetes occurs when cells in the pancreas die off or receptor sites are clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
There are 2 major types of diabetes,
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, is the most common form of diabetes found in children and is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.
* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
The most common symptoms of type 2 diabetes are an increased thirst that won't stop with water intake and increased hunger.
Diabetic complications are any diseases associated with hyperglycemia if the blood glucose is not managed properly. Patients with diabetes may induce several complications including cardiovascular disease, neuropathy, nephropathy, retinopathy, and foot ulcer.
By managing your blood glucose properly and daily, the risk of diabetic complications can be reduced in diabetics by
*Take your medication as directed.
*Keeping tight control of your blood sugar or managing the blood glucose in the required range
* Eating healthy with moderate exercise to protect your weight, blood pressure, and cholesterol. Being overweight, blood pressure, and cholesterol are some of the conditions associated with an increased risk of diabetes complications.
* Get regular checkups
* Quit smoking
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.
In finding a potential phytochemical for the prevention of chronic diseases involved in oxidative stress, researchers investigated the anti-diabetes activity of beta-sitosterol (β-sitosterol) on insulin signaling molecules and glucose oxidation.
According to the differentiation of the adipose tissue of a high-fat diet and sucrose-induced type-2 diabetic experimental rats given the dose of β-sitosterol (20 mg/kg b.wt, orally for 30 days), β-sitosterol normalized the altered levels of blood glucose, serum insulin in the tested rats.
Furthermore, the hormone testosterone, lipid profile, oxidative stress markers, antioxidant enzymes, insulin receptor (IR), and glucose transporter 4 (GLUT4) proteins associated with glucose uptake were also inhibited by the application of beta-sitosterol.
In other words, most parameters associated with the characteristics of diabetes were inhibited by the injection of the bioactive compound.
Based on the findings, researchers aid, "β-sitosterol improves glycemic control through activation of IR and GLUT4 in the adipose tissue of high fat and sucrose-induced type-2 diabetic rats".
Taken altogether, beta-Sitosterol may be considered a supplement for the treatment of diabetes, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In silico and in vivo analysis to identify the antidiabetic activity of beta-sitosterol in adipose tissue of high-fat diet and sucrose induced type-2 diabetic experimental rats by Ponnulakshmi R1, Shyamaladevi B2, Vijayalakshmi P3, Selvaraj J. (PubMed).
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