Tuesday, 22 February 2022

Dandelion (Taraxacum officinale) in the Management and Treatment of Type 2 Diabetes

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.

In other words, diabetes occurs when cells in the pancreas die off or receptor sites are clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

The most common forms of Diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form of diabetes found in children is a condition in which the pancreas does not produce any insulin.

The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

As of today, there is no cure for type 1 diabetes. Treatment is focusing on managing blood sugar levels with insulin injection, diet, and lifestyle change.

* Type 2 diabetes, the most common form of acquired diabetes in adulthood is a chronic condition that affects the body's metabolized glucose. In other words, most cases of type 2 diabetes are the result of insulin receptors clogged up by fat and cholesterol, leading to resisting the effects of the hormone insulin that regulates the movement of sugar into your cells.

* Gestational diabetes is a form of diabetes that can occur during pregnancy, affecting between 3% and 20% of pregnant women.

Women with gestational diabetes are at an increased risk of type 2 diabetes in later life.

* Latent autoimmune diabetes in adults (LADA), similar to type 1 diabetes, is a slow-progressing form of autoimmune diabetes. The disease is caused by the pancreas' inability to produce enough insulin, because of slowly die-off of insulin-producing cells in the pancreas.

LADA is also known as type 1.5 diabetes because the disease has characteristics of both type 1 (autoimmune in nature) and type 2 diabetes.

Therefore, LADA shares the same risk factors and symptoms similar to those types 1 and 2 diabetes.

Unlike type 2 diabetes, patients with LADA do not respond well to seems to lifestyle and medication as in type-2 diabetes in the long term. Medicine used for the treatment of type 2 diabetes does not halt or slow the progression of loss of pancreas beta cells.

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver, and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the prevention and treatment of chronic low-grade inflammatory diseases, scientists examined the dandelion anti-type 2 diabetes (T2D) activity.

According to test differentiation, the root of dandelion contains inulin, including fructooligosaccharides (FOS), a complex carbohydrate that normalizes blood sugar levels.

Other compounds chlorogenic and chicoric acid found in dandelion not only prevent obesity and inflammation but also have a strong impact on insulin secretion and sensitivity.

Other active compounds isolated from dandelion such as sesquiterpene lactones, triterpenes/phytosterols (taraxasterol), phenols, flavonoids, and phenolic acids also have demonstrated a series of anti-diabetic effects, due to the pharmacological actions of components.

In hyperglycemia, a hallmark in T2D fructooligosaccharides (FOS) exerted a significant activity that affects glucose homeostasis in oxidative stress, leading to auto-oxidation and protein glycation and increasing the production of lipid peroxide which in turn decreases the anti-oxidative defense induce β-cell dysfunction.

Furthermore, dandelion also manifests its anti-diabetic properties, through the inhibited renal glucose reabsorption and potassium channel flow, reduced the activity of carbohydrate enzymes (α-amylase with β-galactosidase and α-glucosidase), and reduced dietary blood sugar (which stimulates hepatic glycolysis and glycogenesis).

Based on the findings, researchers said, "Dandelion has been considered a key anti-diabetic plant because of its anti-hyperglycemic, anti-oxidative, and anti-inflammatory properties []. This is due to the various bioactive components present in dandelion, including polyphenolics, sesquiterpenes, triterpenes, and phytosterols".

Taken altogether, dandelion may be considered a remedy for the management and treatment of type 2 diabetes, pending the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The Physiological Effects of Dandelion (Taraxacum Officinale) in Type 2 Diabetes by Wirngo FE1, Lambert MN1, Jeppesen PB. (PubMed)

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