The holistic Prevention, Management and Treatment of Dementia due to aging depletion of Kidney Essence -TCM Herbal Shi Hu(Dendrobium)

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.


   TCM Treatment of Dementia due to aging depletion of Kidney Essence - Herbal Shi Hu(Dendrobium)

Based on Chinese ancient medical records, causes of dementia are the results of (*)
2. Shi Hu(Dendrobium)
The sweet, bland, slightly cold herb, is also known as Dendrobiu, used in traditional Chinese medicine as anti diabetic(1315)(1316), anti-hyperglycemic((1317)(1318))and anti microbial(1319)(1320) agents caused by yin deficiency and to treat thirsty(1315)(1316), thromboangitis obliterans, chronic throat infection, blurry vision(1321)(1322), weak lower back,... by enhancing the lung, stomach channels(1323).

Phytochemicals
1. Ophiopogonin
2. Ruscogenin
3. β-sitosterol β
4. Stigmasterol
5. Dendrobine
6. Nobilonine
7. 6-hydroxydendrobine
8. Etc.

According to Zunyi Medical College, alkaloids enriched extract fromDendrobium Nobile Lindl. (EDNLA), inhibited paired helical filaments of hyperphosphorylation of tau protein, in neurofibrillary tangles, a pathological feature of Alzheimer's disease (AD)(1324). In rat model administrated intragastrically with different doses of DNLA (20, 40 mg/kg), attenuated lipopolysaccharide (LPS, 100 μg) injecting into the bilateral ventricle, induced hyperphosphorylation of tau protein in hippocampus and protected against LPS-induced apoptosis in brain(1325).





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References
(1311) Qigong for Wellbeing in Dementia and Aging by Stephen Rath
(1312) Chinese Medical Psychiatry: A Textbook & Clinical Manual : Including ... By Bob Flaws, James Lake
(1315) Dendrobium chrysotoxum Lindl. alleviates diabetic retinopathy by preventing retinal inflammation and tight junction protein decrease by Yu Z1, Gong C1, Lu B1, Yang L1, Sheng Y2, Ji L1, Wang Z1.(PubMed)
(1316) Ethanol extract of Dendrobium chrysotoxum Lindl ameliorates diabetic retinopathy and its mechanism. by Gong CY1, Yu ZY1, Lu B1, Yang L1, Sheng YC2, Fan YM1, Ji LL3, Wang ZT1.(PubMed)
(1317) [Studies on anti-hyperglycemic effect and its mechanism of Dendrobium candidum].[Article in Chinese] by Wu HS1, Xu JH, Chen LZ, Sun JJ.(PubMed)
(1318) [Studies on anti-hyperglycemic effect and its mechanism of Clinopodium chinense].[Article in Chinese] by Tian DN1, Wu FH, Ma SC, Li D, Dai Y.(PubMed)
(1319) Antimicrobial activity of endophytic fungi isolated from Dendrobium species in southwestern China by Cui J1, Wang Y, Xing Y, Guo S, Xiao P, Wang M.(PubMed)
(1320) Antimicrobial activity and biodiversity of endophytic fungi in Dendrobium devonianum and Dendrobium thyrsiflorum from Vietnam by Xing YM1, Chen J, Cui JL, Chen XM, Guo SX.(PubMed)
(1321) [Experimental study on preclinical quality control, urgent poison and irritation of Dendrobium aurantiacum eye drops, a class I new drug against diabetic cataract].[Article in Chinese] by Yi YQ1, Yang QH, Su JF, Chen J, Qi H, Chen D, Wei XY.(PubMed)
(1322) [Observation on therapeutic effect of runmushu oral liquid in treating xerophthalmia in postmenopausal women].[Article in Chinese] by Wei D1, Li YH, Zhou WY.(PubMed)
(1323)Shi hu(Complementary and Alternative Healing University)
(1324) Alkaloids enriched extract from Dendrobium nobile Lindl. attenuates tau protein hyperphosphorylation and apoptosis induced by lipopolysaccharide in rat brain by Yang S1, Gong Q1, Wu Q1, Li F1, Lu Y1, Shi J2.(PubMed)
(1325) Eucommia ulmoides Oliv. bark. attenuates 6-hydroxydopamine-induced neuronal cell death through inhibition of oxidative stress in SH-SY5Y cells by Kwon SH1, Ma SX1, Hong SI1, Kim SY2, Lee SY1, Jang CG3.(PubMed)