Tuesday, 29 March 2016

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Individual herbs - Valerian

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                  Polymyalagia Arthritis (Rheumatica)

Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.                                  


B.2. Herbal and Traditional Chinese medicine 
Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including 
B.2.1. Individual herb
3. Valerian
Valerian is a perennial flowering plant, in the genus Valeriana, belongings to the family Valerianaceae, native to Europe and parts of Asia  used in traditional herbal medicine as a sedative and relaxing agent and to treat the liver, the urinary tract, the digestive tract problem, nerve conditions, etc.,...According to the University of Peshawar, Valerian expressed anti inflammatory effect on the acute and chronic phase inflammation models in male Wistar rats, on dose dependant manner(202), particular in crude extract at a dose of 200 mg/kg at all observed durations(203).
According to the University of Washington, Valerian may be used as sedative in reduced sleep(200) disturbance of patients induced fatigue(201) with inflammatory rheumatic pain(200).

(200) A feasibility study of valerian extract for sleep disturbance in person with arthritis by Taibi DM1, Bourguignon C, Gill Taylor A.(PubMed)
(201) Non-pharmacological interventions for fatigue in rheumatoid arthritis by Cramp F1, Hewlett S, Almeida C, Kirwan JR, Choy EH, Chalder T, Pollock J, Christensen R.(PubMed)
(202) Anti-inflammatory activity of the topical preparation of Valeriana wallichii and Achyranthes aspera leaves by Khuda F1, Iqbal Z, Khan A, Zakiullah, Nasir F, Shah Y.(PubMed)
(203) Antimicrobial and anti-inflammatory activities of leaf extract of Valeriana wallichii DC by Khuda F1, Iqbal Z, Zakiullah, Khan A, Nasir F.(PubMed)

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