Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Monday 26 June 2017

Herbal Therapy: Cat's claw, The best Whole Herb Medicine for Prevention and Treatment of Inflammatory diseases

Kyle J. Norton, Master of Nutrients

Whole food(herbal medicine), linking health benefits in the prevention, management, and treatment of diseases has placed an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and pattern right to producers.

Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..

The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.

Inflammatory diseases is disorders and conditions caused by inflammation. Cat's claw may be a next generation of the medical plant for treatment of inflammation against various diseases. According to the study by the Case Western Reserve University, Uncaria tomentosa exhibited high levels of anti-inflammatory effects through the interference of the pro-inflammatory expression.

Mitraphylline (MTP), the major pentacyclic oxindole alkaloid presented in Uncaria tomentosa, elicited an anti-inflammatory response that modulates neutrophil activation contributing to the attenuation of inflammatory episodes.

Furthermore, the ingredient, Mitraphylline (MTP) also showed a direct effect in the immune system by reduced almost 40% of the production of interleukin 4 (IL-4) and inhibited around 50% of the release of interleukins.

Indenture Stomatitis, a chronic oral disease that affects denture wearers is caused by Candida Albicans in inducing inflammation. Topical application of a gel of 2% U. tomentosa three times a day for 1 week, cat' claw significantly reduced signs of the disease, after 1 week of treatment.

In fact, the anti-inflammatory properties may also result from their ability to inhibit TNF-alpha, a central regulator of inflammation, and to a lesser production of PGE2, a principal mediator of inflammation in diseases production.

The effects of cat's claw in inhibited inflammatory diseases may result from its binding to proinflammatory cytokines and pathways. Use of the medical plant should be only prescribed by herbal for safety purpose.

Sunday 25 June 2017

Food Therapy: Garbanzo beans( chickpeas) reduce symptoms and complications of patients with diabetes

With Nutrients of

1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Vitamin A
6. Thiamine (Vitamin B1)
7. Riboflavin (Vitamin B2)
8. Niacin (Vitamin B3)
9. Pantothenic acid (B5)
10. Vitamin B6
11. Folate (Vitamin B9)
12. Vitamin C
13. Vitamin E
14. Vitamin K
15. Iron
16. Magnesium
17. Phosphorus
18. Potassium
19. Zinc
20. Etc.

Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

The effectiveness of chickpea in reduced risk of type II diabetes, probably due to the existence of high amount of dietary fiber. According to the Case Western Reserve University, increased consumption of soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals.

People who follow high-fiber, high-carbohydrate diets over time, can see the benefits in controlling body weight, insulin requirements, glycemic control, and serum lipids up to 10 years of follow-up.

In the review of 14 randomized clinical trials, Dr. Wolfram T and research team found that addition of insoluble or soluble fiber to meals, increased consumption of diets rich in whole grains and vegetables, and vegan diets improve glucose metabolism and increase insulin sensitivity. The greatest improvement in blood lipids, body weight, and hemoglobin A(1c) level occurred in participants following low-fat, plant-based diets.

In fact, " High-fiber diets, especially of the soluble variety, and soluble fiber supplements may offer some improvement in carbohydrate metabolism, lower total cholesterol, and low-density lipoprotein (LDL) cholesterol and have other beneficial effects in patients with non-insulin-dependent diabetes mellitus (NIDDM)", Dr. Vinik AI and Dr. Jenkins DJ said.

Furthermore, The American Diabetes Association recommends a goal of 40 g of soluble fiber intake per day for a patient with diabetes.

Taking all together, chickpea with a high amount of dietary fiber may be considered as a functional food in reduced symptoms and complications of patients with diabetes.

Food Therapy: Garlic - The Whole Food Medicine for Reduced Risk and Treatment of Breast Cancer

Kyle J. Norton, Master of Nutrients

Whole food(herbal medicine), linking health benefits in the prevention, management, and treatment of diseases has placed an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and patent right to producers.

Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.

Breast cancer (malignant breast neoplasm) is a cancer that starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk. there is also rare cases that breast cancer starts in other areas of the breast. In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during life time of a women is 1/8.

Fresh Garlic Extract beside inhibited colon and gastric cancer in 2 previous article, it also is found to arrest the growth and alter the morphology of MCF7 breast cancer cells.

Also in MCF7 human breast cancer cells, garlic constituent diallyl trisulfide have highly effective antitumor effects by the suppressesing viability of cultured MCF-7 and MCF-12a cells, through decreased the percent of cells in G(2)/M and induced apoptotic cell death.

According to the study by the 201 South University Street, diallyl trisulfide, inhibited the expression of MDA-MB-231 and MCF-7 breast cancer cells,regardless to the state of estrogen in the tumors.

In a total of in 285 women (aged 25-65 years old) newly diagnosed with histopathologically confirmed breast cancer, dietary Allium Vegetables has a negative association between the consumption of raw onion and risk of breast cancer.

Dr. Roy N., the lead author at the Kerala Agricultural University, said, "Docking studies and ADMET evaluation revealed twelve compounds (isolated from garlic) to be active against the targets(breast caner cell lines). All the compounds displayed highly negative dock scores which indicated good interactions".

Therefore, the effectiveness of garlic in reduced risk and treatment of breast cancer is probably due to existence of many phytochemicals found in the herb. Women who increased intake of garlic everyday, may see the risk of breast cancer reduced substantially.

Saturday 24 June 2017

Herbal Therapy: Cinnamon, the number One Whole Herb Medicine in management of diabetes and its complications

Kyle J. Norton, Master of Nutrients

Whole food(herbal medicine), linking health benefits in the prevention, management, and treatment of diseases has placed an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and patent right to producers.

Intake of cinnamon is found to improve fasting glucose, glucose tolerance and insulin sensitivity in women with insulin resistance associated with the polycystic ovary syndrome.

Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.

Cinnamaldehyde, in the animal study found in the husk of Cicer arietinum L. Monosaccharide, exhibited antioxidant effects in reduced 29% of free radical expression and glucolipid levels through its action on multiple signaling pathways including cell cycle arrest and anti pro inflammatory property.

In vivo and in vitro, administered orally cinnamic acid and cinnamaldehyde lower acute blood glucose and improve glucose tolerance, through stimulating insulin secretion in isolated islets, according to the joint study led by the University of Karachi.

In a 16-week double-blind randomized control trial of 116 individuals with metabolic syndrome, dietary intervention groups with the administration of cinnamon [6 capsules (3 g) daily], significant improve all components of metabolic syndrome in a sample of Asian Indians in north India.

Dr. Gupta Jain S lead author of the researchers said,"Significantly greater decrease [difference between means, (95% CI)] in fasting blood glucose (mmol/L) [0.3 (0.2, 0.5) p = 0.001], glycosylated haemoglobin (mmol/mol) [2.6 (0.4, 4.9) p = 0.023], waist circumference (cm) [4.8 (1.9, 7.7) p = 0.002] and body mass index (kg/m2 ) [1.3 (0.9, 1.5) p = 0.001] was observed in the cinnamon group compared to placebo group".

Other researchers in the study of cinnamon (Cinnamomum cassia) anti-diabetic property on obese patients also suggested, its effectiveness of increased the lipid storage capacity of white adipocytes and increased the fatty acid oxidation capacity may be due to activities of some other components of cinnamon (Cinnamomum cassia) in the prevention of obesity-induced type II diabetes

Although cinnamon (Cinnamomum sp) has shown to express good glycemic control to patients with type 2 diabetes mellitus (T2DM), intake of cinnamon supplement and whole herb should only be given by the qualified herbal doctor to achieve a greater health effect without side effects.

According to traditional Chinese medicine, cinnamon is a very hot herb, overdoses may induce toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Chromium and polyphenols from cinnamon improve insulin sensitivity. by Anderson RA1(PubMed)
(2) Cinnamaldehyde in diabetes: A review of pharmacology, pharmacokinetics and safety by Zhu R1, Liu H1, Liu C2, Wang L1, Ma R1, Chen B1, Li L1, Niu J1, Fu M3, Zhang D4, Gao S5.(PubMed)
(3) Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro by Hafizur RM1, Hameed A2, Shukrana M3, Raza SA2, Chishti S2, Kabir N4, Siddiqui RA2.(PubMed)
(4) Effect of oral cinnamon intervention on metabolic profile and body composition of Asian Indians with metabolic syndrome: a randomized double -blind control trial by Gupta Jain S1, Puri S1, Misra A2, Gulati S3,4, Mani K5.(PubMed)
(5) Stimulatory Effects of Cinnamon Extract (Cinnamomum cassia) during the Initiation Stage of 3T3-L1 Adipocyte Differentiation by Lee SG1, Siaw JA2, Kang HW3.(PubMed)

Herbal Therapy: Cat's claw, The best Whole Herb Medicine for Prevention and Treatment of Inflammatory disease

Kyle J. Norton, Master of Nutrients

Whole food(herbal medicine), linking health benefits in the prevention, management, and treatment of diseases has placed an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and pattern right to producers.

Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..

The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.

Inflammatory diseases is a disorders and conditions caused by inflammation. Cat's claw may be a next generation of medical plant for treatment of inflammation against various diseases. According to the study by the Case Western Reserve University, Uncaria tomentosa exhibited high levels of anti-inflammatory effects through interference of the pro-inflammatory expression.

Furthermore, the ingredient, Mitraphylline (MTP) also showed a direct effect in the immune system by reduced almost 40% of the production of interleukin 4 (IL-4) and inhibited around 50% of the release of interleukins.

In denture Stomatitis, a chronic oral disease that affects denture wearers is caused by Candida Albicans in inducing inflammation. Topical application of a gel of 2% U. tomentosa three times a day for 1 week, cat' claw significantly reduced signs of the disease, after 1 week of treatment.

In fact, the anti-inflammatory properties may also result from their ability to inhibit TNF-alpha, a central regulator of inflammation, and to a lesser production of PGE2, a principal mediator of inflammation in diseases production.

The effects of cat;s claw in inhibited inflammatory diseases may be resulted from its binding to proinflammatory cytokines and pathways. Use of the medical plant should be only prescribed by herbal for safety purpose.

Friday 23 June 2017

Herbal Therapy: Cat's claw, The best Whole Herb Medicine for Prevention and Treatment of Cancers

Kyle J. Norton, Master of Nutrients

Whole food(herbal medicine), linking health benefits in the prevention, management, and treatment of diseases has placed an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and pattern right to producers.

Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..

The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.

Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, becoming progressively worse and damaged other healthy tissues, sometimes spreading to other organs in the body via lymph or blood and results may be in death.

The herbal whole herb medicine may be used for the treatment of various cancers. In a recent study, cat's claw chemotypes showed a directed influence on genotoxicity and cytotoxicity against nonmalignant and malignant human cell lines.

In T24 and RT4 human bladder cancer cell lines, bark samples extracted by dynamic maceration, alkaloids or isomerized derivative significant induced cytotoxic activity in dose-dependent
manner, leading to cells death in the tumor cell divisive process.

According to the Universidade Federal do Rio Grande do Sul (UFRGS) in joint study with other renowned institutions, Quinovic acid glycosides purified fraction (QAPF) of U.tomentosa found in Cat' claw decreased the growth and viability and protected against cell proliferation in both T24 and RT4 cell lines, through interfering with the inflammation, immunity, cell proliferation, differentiation pathway.

In a total of fifty-one volunteers recruited with the median age was 64 (range, 33-85) years, and 47% of patients were female, cat's claw improves quality of life and symptom of fatigue in patients with advanced cancer.

Dr. Dreifuss AA, the lead author at the Cayetano Heredia Peruvian University said, that In vivo, UT hydroalcoholic extract demonstration of both antitumoral and antioxidant effects. The antineoplastic activity may be the result in regulated redox and metabolism homeostasis as well as anti-neoplastic effects.

Taking together, the whole herb Cat's claw may be used for the prevention and treatment of cancers, but the prescribed quality must be given by the herbal doctor to reduce the risk of overdoses.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Genotoxicity and cytotoxicity of oxindole alkaloids from Uncaria tomentosa (cat's claw): Chemotype relevance by Kaiser S1, Carvalho ÂR2, Pittol V2, Dietrich F3, Manica F3, Machado MM4, de Oliveira LF4, Oliveira Battastini AM3, Ortega GG2.(PubMed)
(2) Cat's claw oxindole alkaloid isomerization induced by cell incubation and cytotoxic activity against T24 and RT4 human bladder cancer cell lines by Kaiser S1, Dietrich F, de Resende PE, Verza SG, Moraes RC, Morrone FB, Batastini AM, Ortega GG.(PubMed)
(3) Quinovic acid glycosides purified fraction from Uncaria tomentosa induces cell death by apoptosis in the T24 human bladder cancer cell line by Dietrich F1, Kaiser S2, Rockenbach L1, Figueiró F1, Bergamin LS1, da Cunha FM3, Morrone FB4, Ortega GG2, Battastini AM5.(PubMed)
(4) Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumors by de Paula LC1, Fonseca F, Perazzo F, Cruz FM, Cubero D, Trufelli DC, Martins SP, Santi PX, da Silva EA, Del Giglio A.(PubMed)
(5) Antitumoral and antioxidant effects of a hydroalcoholic extract of cat's claw (Uncaria tomentosa) (Willd. Ex Roem. & Schult) in an in vivo carcinosarcoma model by Dreifuss AA1, Bastos-Pereira AL, Avila TV, Soley Bda S, Rivero AJ, Aguilar JL, Acco A.(PubMed)
(6) Uncaria tomentosa exerts extensive anti-neoplastic effects against the Walker-256 tumour by modulating oxidative stress and not by alkaloid activity by Dreifuss AA1, Bastos-Pereira AL, Fabossi IA, Lívero FA, Stolf AM, Alves de Souza CE, Gomes Lde O, Constantin RP, Furman AE, Strapasson RL, Teixeira S, Zampronio AR, Muscará MN, Stefanello ME, Acco A.(PubMed)

Thursday 22 June 2017

Food Therapy: Garbanzo bean(Chickpea), The Best whole food medicine for reduced risk and symptoms of Cardiovascular diseases

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Whole food(herbal medicine), linking health benefits in the prevention, management, and treatment of diseases has placed an important role in human history over many centuries. The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and pattern right to producers.

Garbanzo beans also known as chickpea is an edible legume of genus Cicer and the family Fabaceae, high in protein and minerals. It is one of the earliest cultivated vegetables, native to the Middle East.

With Nutrients of

Chickpea with a high amount of fiber along with the relevant antioxidant capacities may be considered as a functional ingredient of antioxidant for reduced risk and symptoms of Cardiovascular diseases.

Besides cancer, heart disease kills more than 2,000 Americans every day. Approximately 60 million Americans have heart disease.

Most of the heart diseases are caused by high blood pressure contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat. All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.

According to the International Crops Research Institute for the Semi-Arid Tropic, chickpea with Chickpea with significant amounts of all the essential amino acids except sulphur-containing amino acids and important vitamins such as riboflavin, niacin, thiamin, folate and the vitamin A precursor β-carotene may have beneficial effects on some of the important human diseases such as Cardiovascular diseases.

Researchers also looked at the total polyphenol and flavonoids concentration and protein concentrations. Both ingredients showed to express antioxidant activity in induced postprandial glycemic excursions and reduced postprandial glycemic load which are the independent risk factor for the development of cardiovascular disorders (CVD),

Furthermore, in the study of independent risk of CVD, fiber intake found abundantly in chickpeas showed to associate to Cardiac vascular disease (CVD). In total, 157 patients included in this study, dietary fiber intake can retard the decrease in the Estimated Glomerular Filtration Rate eGFR, reduce the levels of proinflammatory factors, indoxyl sulfate, and serum cholesterol; and is negatively associated with cardiovascular risk.

In fact, intake of the fiber of any sources has shown to reduce the risk of numbers of disease. According to the Biomedical Research Institute Sant Pau - Cardiovascular Research Center Barcelona, fiber is taken together with phytosterols, vitamins and minerals( found in chickpea), exert antioxidant, anti-inflammatory and anti-thrombotic effects contributing to the delay of CVD initiation and progression.

Taken altogether, patients with or without cardiovascular disease may want to include chickpea in their diet, accompanied with good sources of vegetables and fruits.