Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Friday, 3 November 2017

Food Therapy: Coffee Intake < 3 Cups/day In Reduced Risk of Gastric Cancer

According to the joint study led by the the Children's Hospital of Chongqing Medical University, by searching of the data base of published literature, including 22 studies (9 cohort and 13 case-control studies) involving 7,631 cases and 1,019,693 controls, the relative risk of gastric cancer and coffee intake was shown in following
1. Relative rsik of gastric cancer was 0.94 (95% CI: 0.80-1.10) for the highest category of coffee consumption compared with the lowest category
2. In compared to non drinker, the relative risk is and 0.93

3. The relative risk of <1 cup/day, 1-2 cups/day and 3-4 cups/day coffee consumption compared with nondrinkers were 0.95, 0.92 and 0.88, respectively,

The information findings, after considering other factors, demonstrated a significant association between coffee intake and decreased gastric cancer risk in case-control studies.

Contraditively, in the study of long term effect of coffee consumption and risk of gastric cancer in US, through searching PubMed and Embase from January 1996 through February 10, 2015 of a total of 2019 gastric cancer incident cases among 1,289,314 participants with mean follow-up periods ranging from 8 to 18 years, suggested that
1. The relative risk (RR) of every 3 cups/day increment of total coffee consumption was 1.07
2. the relative risk of 1.18 in compared with the lowest and the highest categories of coffee consumption
3. RR of 1.06 in compared the second highest and Lowest category (median 3.5 cups/day),
4 RR of 0.97 (95% CI = 0.79-1.20) for the third highest and lowest category (median 1.5 cups/day).

Dr., the lead author said, "Current evidence indicated there was no nonlinear association between coffee consumption and gastric cancer risk. However, high coffee consumption (more than 6.5 cups/day) might increase the risk of gastric cancer in the US population".

Other, subgroups analysis suggested that coffee intake do not have potential effect in gastric risk, but in US subgroup, risk of gastric significant increased risk with the relative ratio of 1.36 in the studies with <10 years of follow-up, particular in those studies without adjustment for smoking.

Taking altogether, although there is conflict evidences, coffee consumption < 3 cups/day was shown to ameliorated risk of gastric cancer.

Food Therapy; Coffee Intake In Increased Risk of Bladder Cancer

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Coffee consumption may have a linear association to potential risk of bladder cancer development,
a respectable institute postulated.

Bladder cancer is medical condition of cell growth irregularly and disorderly in the bladder. The cancer may spread to distant tissues and organs in the later stage.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the Shandong University, in the review literature published online satisfied the criteria and guideline to investigate risk of bladder cancer among coffee consumption adults. Selected studies, numbers of cups/day and relative risk RR as follow
For 23 case-control studies
1. for 1 cup/day, RR=1.07
2 for 2 cups/day, RR=1.15
3 for 3 cups/day, RR=1.22
4. for 4 cups/day RR= 1.29
and
For 5 cohort studies
1. for 1 cup/day, RR=1.09
2. for 2 cups/day, RR=1.13
3. for 3 cups/day, RR= 1.09
4 for 4 cups/day, RR=1.01

The findings in both case-control and cohost studies showed a positive association of coffee intake and risk of bladder cancer.

In non smokers, according to the pooled data set comprises 564 cases and 2929 hospital or population controls enrolled in ten studies conducted in Denmark, Germany, Greece, France, Italy and Spain. risk of bladder caner did not increase monotonically with dose but for heavy coffee drinkers of over 10 cups per days, the risk bladder cancer increases substantially.

Dr. Sala M, the lead author said, "Nonsmokers who are heavy coffee drinkers may have a small excess risk of bladder cancer".

Other, in the analysed a case-control study in two different areas of northern Italy (555 cases and 855 controls), coffee intake and risk of bladder cancer showed that
in compared to non drinkers(RR: relative risk ratio)
1. RR 1.2 for one cup of coffee per day,
2. RR 1.4 for two,
3. RR 1.5 for three and
4 RR 1.4 for four or more
5. RR 1.5 (0.9-2.4) for decaffeinated coffee.
But in never smoked participants, the risk of bladder cancer increased significantly
1 .RR 1.9 for one or two cups per day,
2. RR 1.8 for three and
3 RR 1.5 for four or more

Taking together, there is no doubt that coffee and coffee caffeine consumption have a significant risk in exhibited incidence of bladder cancer regardless to numbers of cups intake daily and regularly.

Food Therapy: Coffee and Coffee Caffeine in Reduced Risk and Treatment of impaired fasting glucose

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

In take of coffee and coffee caffeine daily and regularly is associated to reduced risk and treatment of abnormal fasting glucose levels, epidemiological studies suggested.

Impaired fasting glucose is a condition characterized by abnormal high blood glucose after meal and considered as an indication of prediabetes or symptoms of diabetics.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

In a prospective study, 910 adults aged >/=50 years without diabetes at baseline in 1984-1987 followed to 1992-1996, an average of 8 years after assessment of coffee intake, researchers found that
past and current coffee drinkers not only had a reduced risk of incident diabetes but also improved impaired glucose in compared with those who never drank coffee.

In 317 participants who are past or current coffee drinkers showed a significant reduced level of fasting blood glucose in compared to the baseline.

Based on an oral glucose tolerance test (OGTT), Dr. Smith B, the lead author said, "This study confirms a striking protective effect of caffeinated coffee against incident diabetes".

Interestingly, in a study comprised 7949 healthy Swedish subjects aged 35-56 years residing within five municipalities of Stockholm. An oral glucose tolerance test identified 55 men and 52 women with previously undiagnosed type 2 diabetes and 172 men and 167 women with impaired glucose tolerance, researchers at the Karolinska Institutet,file the following results

1. The relative risks when drinking >/=5 cups of coffee per day compared with </=2 cups per day in men were 0.45 and 0.63, respectively, and after adjustment of type 2 diabetes and impaired glucose tolerance but in women, the relative risk was reduced substantially to 0.27.

2. Coffee and coffee caffeine intake was associated inversely in patients with type 2 diabetes.
3. Women, but not in men, with impaired glucose tolerance also benefit from improvement of beta-cell function
4. Both gender with normal glucose tolerance, coffee consumption also displayed a strong effect in reduced risk of insulin resistance.

Dr. Agardh EE, the led author said, "high consumers of coffee have a reduced risk of type 2 diabetes and impaired glucose tolerance. The beneficial effects may involve both improved insulin sensitivity and enhanced insulin response".

Additionally, in a study of subsample of subjects aged 45 to 64 years in 1987 and in 1992 from the population-based FINRISK study (12,287 individuals) invited to receive the standard oral glucose tolerance test at baseline, the fasting and two-hour plasma glucose and insulin measured in 2434 subjects, researchers postulated that according to the data, coffee demonstrated a significantly and inversely associated with fasting glucose, two-hour plasma glucose, and fasting insulin in both men and women.

In fact, intake of coffee in the sample also showed a profound effect in ameliorated impaired fasting glucose, improved impaired glucose regulation, and hyperinsulinemia in both gender, particularly in several glycemia markers.

Conclusively, Coffee, not only is a source of chemical compounds such as chlorogenic acids and lignans in improved glucose metabolism,but also may be considered as a novel mechanisms for effects of diet on Reduced Risk and Treatment of impaired fasting glucose and prevent the development of type 2 diabetes.

Food Therapy: Coffee and Coffee Caffeine in Increased Insomnic Occurrence

By Kyle J. Norton

Coffee consumption may have a negative effect in induced insomnic occurrence, a renowned institute study suggested.
.
Insomnia is a condition characterized by unable to sleep regularly and normally

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

In a total of 7698 subjects aged 11-17 years included in the investigation of a cross-sectional study within the German Health Interview and Examination Survey for Children and Adolescents.Self-report questionnaires returned by participants showed that
1. Frequent coffee consumption, accompanied with high alcohol intake and frequent smoking may be associate to prediction of IC in male subjects
2. Frequent coffee consumption and high alcohol intake also induced predicted occurrence of insomnia IC in females.

After taking into account of other factors, researchers emphasized that coffee consumption may be an important risk factor for IC in adolescents and had a significantly affects in association of smoking, alcohol, and marijuana with IC.

Additionally, in the study conducted by the Instituto Politécnico de Viseu included 6,919 students from the 7th to the 12th grade from 26 secondary schools, during 2012 with data collected, using a self-administered questionnaire, researchers filed the following results
1. The prevalence of symptoms of insomnia was 21.4 %, and the prevalence of insomnia was 8.3 %
2. After adjustment for gender and age, insomnia effects mostly in the female gender
3. Coffee and alcohol consumption showed a significant risk of insomnia with adjusted relative risk of 1.63

According to the finding information, Dr. Amaral MO, the lead author said, " The main risk factors for insomnia among these adolescents are gender (female), age (≥ 16 years), depression, and coffee and alcohol consumption, which is also in concordance with those in the literature".

Furthermore, in rats, radiotelemetry transmitters with electroencephalogram and electromyogram electrodes implanted for sleep recording in animals administered with caffeine alone (10 mg/kg) or in combination with zolpidem (10 mg/kg) or trazodone (20 mg/kg), or vehicle, in crossover experiments with 12 healthy male volunteers in a randomised, placebo-controlled, 4-week crossover study, caffeine injection group showed a significant prolongation in objective sleep onset latency (SOL) with disruption in subjective measures of sleep onset caused by caffeine in rats and humans in compared to other groups.

Taking together, coffee and coffee caffeine may have disruptive effect in induced insomnia and symptoms of insomnia, particularly in female, therefore women who have a history of insomnia should reduced intake of coffee or only drink them in the morning at reduced amount.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Insomnia complaints and substance use in German adolescents: did we underestimate the role of coffee consumption? Results of the KiGGS study by Skarupke C1, Schlack R2, Lange K1, Goerke M3, Dueck A4, Thome J5, Szagun B6, Cohrs S7.(PubMed)
(2) Prevalence and risk factors for insomnia among Portuguese adolescents by Amaral MO1, de Figueiredo Pereira CM, Silva Martins DI, de Serpa Cdo R, Sakellarides CT.(PubMed)

Thursday, 2 November 2017

Food Therapy: Coffee and Coffee Caffeine in Reduced Early Onset and Treatment of Dementia

By Kyle J. Norton

Epidemiological studies, linking coffee and coffee caffeine in reduced risk of early onset and treatment of dementia have been well documented, according to the joint study by renowned institutes,

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

Dementia is neurodegenatively chronic and medical condition characterized by memory disorders, personality changes, and impaired reasoning,,,,,

According to the joint study lead by the University of Bari Aldo Moro, coffee and coffee caffeine drunk regularly by millions of people around the world as best known psychoactive stimulant may have an explicit effect in heightened alertness and improvement of cognitive performance, thus reducing risk of the development of dementia and late-life cognitive disorders.

In some case-control and cross-sectional and longitudinal population-based studies to evaluate the long-term effects on brain function, researchers suggested that coffee, tea, and caffeine consumption or higher plasma caffeine levels exhibited neuro protective effects against cognitive impairment/decline and dementia.

Intake of coffee and coffee caffeine efficacy in reduced risk of onset neuro impairment depended not only on amount of cups consumed per days but also in expression of gender difference.

Additionally, a review of the longitudinally epidemiological studies about caffeine,/coffee, /tea and dementia/AD/cognitive functioning study, indicated that coffee consumption is associated to favorable effects against cognitive decline, dementia or AD.in most studies (3 out of 5).
And combined coffee and tea drinking demonstrated some positive effects on cognitive functioning. in the other 2 studies.

In fact, the reviewed study also point out that coffee and coffee caffeine intake regularly and daily against the onset of dementia may be attributed to various mechanisms, including antioxidant and caffeine capacity and increased insulin sensitivity.

Dr. Eskelinen MH, the lead author said, " In the CAIDE study, coffee drinking of 3-5 cups per day at midlife was associated with a decreased risk of dementia/AD by about 65% at late-life".

Progressively, the midlife coffee and tea drinking and risk of Aging and Dementia (CAIDE) study, suggested that people drinking 3-5 cups per day in their midlife may benefit to a decreased dementia risk of over 65%.

More importantly, the follow up follow-up of 21 years, 1409 individuals (71%) aged 65 to 79 completed the re-examination in 1998 of a randomly selected from the survivors of a population-based cohorts previously surveyed within the North Karelia Project and the FINMONICA study in 1972, 1977, 1982 or 1987 (midlife visit). also postulated that coffee and coffee caffeine intake at midlife showed a significantly lower risk of dementia and AD later life in compared with those drinking no or only little coffee after adjusted for other factors.

Taking together, there is no doubt that coffee and coffee caffeine consumption had a profound effect in reduced on set and treatment of dementia in dose and gender depending manner.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review by Panza F1, Solfrizzi V, Barulli MR, Bonfiglio C, Guerra V, Osella A, Seripa D, Sabbà C, Pilotto A, Logroscino G.(PubMed)
(2) Caffeine as a protective factor in dementia and Alzheimer's disease by Eskelinen MH1, Kivipelto M.(PubMed)

Food Therapy: Coffee Intake Daily and Regularly in Increased Risk Of Laryngeal Cancer?

Kyle J. Norton, Master of Nutrients

Epidemiological studies do not agreed that coffee and coffee caffeine may have potential in reduced risk and treatment of laryngeal cancer.

Laryngeal cancer is a medical condition of irregular cell growth in the tissues of the larynx. The cancer cells may spread to other tissues and organs in the late stage.

Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

In the review literatureof a total of 2,803 cases and 503,234 controls in 10 independent studies identified by searching electronic database (Medline and EMBASE) and reviewing the reference lists of relevant articles until Oct. 2013, researchers found that incidence of larygeal cancer was associated to coffee consumption, in compared to non drinkers. Intake of coffee showed a significant relative risk of RR = 1.47 in compared to base line.

Interestingly, researchers found, no statistically significant association of cancer incident difference in comparison between moderate and low coffee drinking .

According to the study, there was a evidence of statistically significant association of dose of coffee consumption and risk of laryngeal cancer.

Dr. Chen J, the lead researcher said, " A dose-response relationship between coffee intake and laryngeal carcinoma was detected" and "this meta-analysis of observational studies demonstrate that coffee consumption would increase the laryngeal cancer risk".

According to the result published, the study also identified that among the 6 studies that reported the association between coffee consumption and laryngeal carcinoma, only one study was a prospective population based cohort study, while the rest 5 studies were retrospective hospital based case-control studies using observation of returned survey from participants.

Contrastively, also in the searching of data base PubMed, Web of Knowledge and Wan Fang Med Online, identified 8 studies including 2167 laryngeal cancer cases, researchers insisted that there was insignificant association between coffee and coffee caffeine intake and risk of laryngeal cancer, regardless to volumes intake.

Taking together, coffee and coffee caffeine intake may have a negative effect in increased risk and laryngeal cancer but researchers suggested that genetic and environmental factors such as alcohol intake, human papillomaviruses infection, and silica exposurem should be also taken into account. which were excluded in some studies before expressing.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Tea and coffee consumption and risk of laryngeal cancer: a systematic review meta-analysis by Chen J1, Long S1.(PMC )
(2) Association between tea and coffee consumption and risk of laryngeal cancer: a meta-analysis by Ouyang Z1, Wang Z2, Jin J1.(PubMed)

Food Therapy: Coffee in Improved Vascular Function in Reduced cardiovascular Risks and Complications

By Kyle J. Norton

Coffee may have a profound effect in stimulated function of arteries and veins to provide nutrients and fluids to the body through blood and water circulation, a joint study suggested.

Vascular function is the action of arteries and veins, in imvolving blood and water circulation in the body.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the study lead by the University of Reading, chlorogenic acids isolated from coffee roasted bean, acutely improved vascular function, partly acting as a mediators mediated by 5-CQA in regulated the normal function of arteries and veins.

In an acute randomized, controlled, cross-over human intervention trials conducted to examine the impact of coffee intake, matched for caffeine but differing in CGA content (89, and 310 mg) on flow-mediated dilatation (FMD) in 15 healthy male subjects, in compared a second intervention trial conducted with 24 healthy male subjects, the impact of pure 5-caffeoylquinic acid (5-CQA), the main CGA in coffee(5-CQA; 450 mg and 900 mg) on FMD, researchers filed the following results
1. Low and high CGA(89 mg and 310 mg CGA) intake, showed a significant effect on vascular function 1 hour after injecting coffee
2. Coffee intake was found closely associated to the paralleled to the appearance of CGA metabolites in regulated the normal function of arteries and veins at 5 hours

3. 5-CQA (450 mg) expressed an improvement by FMD assay after i hour of administration.

The information findings suggested that coffee has a strong effect in activated vascular function through its phytochemicals, including CGA and its metabolites in plasma, 3-, 4- and 5-feruloylquinic acid and ferulic-4'-O-sulfate at 1 h and isoferulic-3'-O-glucuronide and ferulic-4'-O-sulfate.

Other, in a total of 38 men and 37 women with a mean ± SD age of 38.5 and body mass index of 24.1 randomly assigned to 3 groups: a control group that did not consume coffee or a placebo and 2 groups that consumed 400 mL coffee/d for 8 wk containing a medium (MCCGA; 420 mg) or high (HCCGA; 780 mg) CGA content, researchers filed the results as follow
1. Coffee consumption over the period indicated and after 1 hours showed a significant presence of caffeic and ferulic acid concentrations in the coffee-drinking groups, with different values in 2 coffee injection group.
2. In the same time as in 1, the levels of antioxidant expression increased substantially in 2 coffee intake group, but undetectable in control group or placebo.
3. All amount of antioxidants and phytochemicals creased to exist after 8 weeks.

The evidences in the study demonstrated a acute effect of coffee in promoting of vascular function in improved nutrients and fluids transportation by arteries and vessels.

Dr. Agudelo-Ochoa GM, the lead author said, "Both coffees, which contained CGAs and were low in diterpenes and caffeine, provided bioavailable CGAs and had a positive acute effect on the plasma AC in healthy adults and no effect on blood lipids or vascular function" and "The group that did not drink coffee showed no improvement in serum lipid profile, FMD, BP, or NO plasma metabolites".

Taking together, there is no doubt that coffee consumption have an enormous effect in improved vascular function in reduced risk of cardiovascular incidence and complications.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: Two randomized, controlled, crossover intervention trials by Mills CE1, Flury A2, Marmet C3, Poquet L3, Rimoldi SF2, Sartori C4, Rexhaj E2, Brenner R2, Allemann Y2, Zimmermann D3, Gibson GR1, Mottram DS1, Oruna-Concha MJ1, Actis-Goretta L3, Spencer JP5.(PubMed)
(2) Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial by Agudelo-Ochoa GM1, Pulgarín-Zapata IC2, Velásquez-Rodriguez CM3, Duque-Ramírez M4, Naranjo-Cano M5, Quintero-Ortiz MM5, Lara-Guzmán OJ6, Muñoz-Durango K2.(PubMed)