Sunday 7 February 2021

Omega -3 Fatty Acids Inhibits the Risk and Onset of Coronary Artery Disease

By Kyle J. Norton

Cardiovascular diseases (CVD) are a group of conditions associated with blood vessels and the heart.

According to the statistics provided by the World Health Organization, cardiovascular diseases are the number 1 cause of death globally. Approximately, 17.9 million people died from CVDs in 2016, representing 31% of all global deaths.

The most common risk factors associated with CVD are an unhealthy diet, physical inactivity, smoking, and excessive alcohol drinking.

Patients with CVD mostly were found to have some intermediate conditions such as high blood pressure, cholesterol, and glucose and being overweight and obese.

Most common CVD are coronary heart disease, which is a condition of narrowing coronary arteries that lead to blockage of the blood flow in the arteries as a result of hardening arterial wall, cholesterol building up in the arteries, chemicals, such as cadmium clog up arteries, etc. affecting the small blood vessels that supply blood and oxygen to the heart. 

Coronary heart disease (CHD) is the leading cause of death in the United States.

According to statistics, coronary artery disease is the most common type of heart disease that causes the death of over 370,000 people every year, representing 28% of all death in the United States.

Sadly, according to the Centers for Disease Control and Prevention, approximately, 735,000 Americans have a heart attack each year.

What causes plaques building up on the arterial is debatable. However, researchers suggested that the Western diet is associated with a significantly increased risk of coronary artery disease.

The most common symptoms of coronary artery disease are angina, the condition characterized by chest pain or discomfort and shortness of breath as a result of the weakening of heart muscle which can not pump enough blood to the body's needs.

Over time, the prolonged weakened heart muscle can lead to complications of heart failure, irregular heartbeat, or arrhythmia.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of heart diseases, researchers examined the effects of Omega-3 polyunsaturated fatty acids on coronary artery disease.

According to the tested analysis,
* Omega-3 polyunsaturated fatty acids showed a protective activity associated with a decreased risk for myocardial infarction in populations with high marine food intake, as well as on lipid metabolism, thrombosis, and inflammation.

* Omega-3 fatty acids decrease triglyceride levels and also compete as substrates for enzymes involved in the biosynthesis of lipid mediators.

* The balance between omega-3-derived specialized pro-resolving mediators and pro-inflammatory lipid mediators from arachidonic acid metabolism against atherosclerosis, the early stage of coronary artery disease.

Collectively, researchers said, " The results of experimental, observational and randomized studies of omega-3 fatty acids are somewhat variable and should be interpreted in view of the models used and the populations studied".

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the prevention and treatment of coronary artery disease, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 fatty acids in atherosclerosis and coronary artery disease by Bäck M. (PubMed)
(2) The balance of omega-3 polyunsaturated fatty acids for -reducing residual risks in patients with coronary artery disease by Nishizaki Y1, Shimada K1, Daida H. (PubMed)

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