Saturday, 30 January 2021

Elevated Levels Alpha-Tocopherols May Be Associated with Increasing the Risk of Uterine Fibroids

By Kyle J. Norton

Fibroids, also known as Fibromyoma uteri or leiomyoma uteri, are benign tumors originating from the muscle tissue that adhere to either the inner or outer of the uterine wall.

According to the statistic from National Uterine Fibroid Foundations, approximately 80% of all women have uterine fibroids with the majority usually have no symptoms. Every 10 minutes, 12 hysterectomies are performed in the United States alone.

If you are experiencing certain symptoms of Uterine bleeding, pelvic pressure, painful periods and sexual intercourse,  abdominal discomfort or bloating and painful defecation, it is advised that you should check with your doctor for fibroids.

After taking the family history and physical exam, diagnosis for uterine fibroids, including
* Pelvic examination
Pelvic examination when there is no menstruation and advised not to have sex for at least 24 hours, is the type of complete physical exam of a woman pelvic organ by a medical instrument to detect any infection, abnormal cells growth such as cysts, fibroid, Etc. The pap test usually is also taken. If your doctor found any abnormal cells growth or suspected uterine cancer, further tests may be suggested, including

* Pelvic ultrasound
Ultrasound allows your doctor to visualize the kidneys and around structures and to assess blood flow to the uterus as well as looking for any abnormal cells growth mass, including fibroids.

* Pelvic MRI
MRI (magnetic resonance imaging) is one of much-advanced technology used to visualize internal structures cross-sectional imaging of your body.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of females reproductive diseases, researchers examined the effect of Alpha-Tocotrienol (AT) against uterine fibroids (UFs).

According to a retrospective cohort study performed in a university teaching hospital with a total of 162 patients divided into 2 groups: with UFs and controls, the mean AT serum concentrations were 11.66 ± 4.97 μg/ml and 7.83 ± 3.13 μg/ml (medians 10.56 μg/ml and 7.42 μg/ml) in patients with UFs and controls, respectively.

In other words, women with elevated levels of mean AT serum concentrations are associated with a  factor for the onset of UTs, compared to women without UFs, particularly in Caucasian women.

Moreover, higher BMI, positive family history, and low parity were found to be major risk factors for UFs. 

Collectively, researchers said, "the development of UFs is determined by several factors, but steroids (estrogen and progesterone) and their receptors seem to play a major role in this process".


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Alpha-Tocopherol Serum Levels Are Increased in Caucasian Women with Uterine Fibroids: A Pilot Study by Ciebiera M1, Szymańska-Majchrzak J2, Sentkowska A3, Kilian K3, Rogulski Z4, Nowicka G5, Jakiel G1, Tomaszewski P6,7, Włodarczyk M. (PubMed)

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