Wednesday 4 April 2018

Eating Healthy, Replace Sugar with This Ingredient to Enjoy 22 Medical Benefits, According to PubMed

Kyle J. Norton.

Consumption of added sugars has a strong implication in increased risk of a variety of chronic diseases including obesity, cardiovascular disease, diabetes and non-alcoholic fatty liver disease (NAFLD) as well as cognitive decline and even some cancers(3).

To replace 1 cup of white sugar you can substitute it for 3/4 cup honey.

According to the the Universtà Politecnica delle Marche,
* Honey positively affects risk factors for cardiovascular diseases by inhibiting inflammation[1], improving endothelial function[2], as well as the plasma lipid profile[3], and increasing low-density lipoprotein resistance to oxidation[4](4). 

* Honey also displays an important antitumoral capacity[5], where polyphenols again are considered responsible for its complementary and overlapping mechanisms of chemopreventive activity in multistage carcinogenesis, by inhibiting mutagenesis or inducing apoptosis(4). 

*Moreover, honey positively modulates the glycemic response by reducing blood glucose[6], serum fructosamine[7] or glycosylated hemoglobin[8] concentrations and exerts antibacterial properties caused by its consistent amount of hydrogen peroxide[9] and non-peroxide[10] factors as flavonoids, methylglyoxal and defensin-1 peptide"(4).


Here are health benefits of honey

The rich golden liquid is the miraculous product made by bees using nectar from flowers. It is considered as one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Nutrients
1. Carbohydrates
2. Sugars
3. Protein
4. Water
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (Vitamin B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Iron
13. Magnesium
14. Phosphorus
15. Potassium
16. Sodium
17. Zinc


A. health benefits according to studies
1. Acute cough in children[11]
In the investigation of the effectiveness of honey for acute cough in children in ambulatory settings found that Dextromethorphan and honeydid not differ significantly on cough frequency (MD -0.49; 95% CI -1.15 to 0.17); cough severity (MD -0.50; 95% CI -1.28 to 0.29), bothersome cough(MD -0.29; 95% CI -1.14 to 0.56) and sleep quality of the children (MD -0.70; 95% CI -1.57 to 0.17) or their parents (MD -0.34; 95% CI -1.24 to 0.55) and concluded that we found insufficient evidence to advise for or against the use of honey for acute cough in children, according to "Honeyfor acute cough in children" by Oduwole O, Meremikwu MM, Oyo-Ita A, Udoh EE.(a)

2. Wound healing[12]
In the assessment of Potential role of honeyon wound healing found that honey may improve healing times in mild to moderate superficial and partial thickness burns compared with some conventional dressings. Honey dressings as an adjuvant to compression do not significantly increase leg ulcer healing at 12 weeks.

There is insufficient evidence to guide clinical practice in other areas. according to "Honey as a topical treatment for wounds" by Jull AB, Rodgers A, Walker N.(b)

3. Antiproliferative effect[13]
In the identification of honey and its effect on keloid fibroblasts found that the methanolic honey extraction has an antiproliferative effect on keloid fibroblasts and a range of volatile compounds has been identified from Tualang honey.

The antiproliferative effect of keloid fibroblasts towards Tualang honey may involve cell signaling pathway.

Identifying other volatile compounds from different organic solvents should be carried out in future, according to "Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts" by Nurul Syazana MS, Halim AS, Gan SH, Shamsuddin S.(c)

4. Antibacterial properties[14]
In the classification of Honey possesses therapeutic potential on antibiotic resistance of bacteria
found that Tualang honey exhibited variable activities against different microorganisms, but they were within the same range as those for manuka honey. This result suggests that tualang honey could potentially be used as an alternative therapeutic agent against certain microorganisms, particularly A. baumannii and S. maltophilia, according to "The antibacterial properties of Malaysian tualang honey against woundand enteric microorganisms in comparison to manuka honey" by Tan HT, Rahman RA, Gan SH, Halim AS, Hassan SA, Sulaiman SA, Kirnpal-Kaur B.(d)

5. Anti-inflammatory and antioxidant effects[15]
In assessment of Tualang honey and its anti-inflammatory and antioxidant effects found that Tualang honey has almost the equal effects when compared with the conventional treatment in treating alkali injury on rabbit's eye. Future research with more number of rabbits and control group is warranted to explore the anti-inflammatory and antioxidant effects of Tualang honey, according to "Anti-inflammatory and antioxidant effects of Tualang honey in alkali injury on the eyes of rabbits: experimental animal study" by Bashkaran K, Zunaina E, Bakiah S, Sulaiman SA, Sirajudeen K, Naik V.(e)


B. Health benefits according to concentration
Honey contains high amount of glucose and fructose that are simple sugar (monosaccharide) played an important role to enhance energy production in carbohydrate metabolism, as they
are absorbed by the body quickly through insulin and potassium[16].

C. Other health benefits
1. Antiseptic[17] and antibacterial properties[18]
Recently research study that honey have the antiseptic and antibacterial properties as it increases the immune system in fighting the forming of free radicals causes of inflammation and infection causes of infection due to enzyme glucose oxidase, according to the study of `Antibacterialproperties of tualang honey and its effect in burn wound management: a comparative study`by Nasir NA, Halim AS, Singh KK, Dorai AA, Haneef MN., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20576085), researchers found that Tualang honey has a bactericidal as well as bacteriostatic effect. It is useful as a dressing, as it is easier to apply and is less sticky compared to Manuka honey. However, for Gram positive bacteria, tualang honey is not as effective as usual care products such as silver-based dressing or medical grade honey dressing.

2. Diabetes chronic wound[19]
External used is proven to be effective for treating diabetes chronic wound that antibiotic can not be used, according to the study of `Safety and efficacy of a new honey ointment on diabetic foot ulcers: a prospective pilot study`by Abdelatif M, Yakoot M, Etmaan M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/18376651, researchers indicated that Ninety-six per cent of the patients in groups 1 and 2 responded well, with a complete cure, defined as'complete closure of the ulcer without signs of underlying bone infection' by the end of week 9 and for the duration of the six-month follow-up period. All of the ulcers in group 1 healed, as did 92% of those in group 2. All patients in group 3 healed following surgical excision, debridement of necrotic tissue and conservative treatment with PEDYPHAR ointment.

3. Phosphorus[20]
Beside providing strength to bones and teeth by working together with calcium according to the study of `[The effect of one year therapy with recombinant human growth hormone (rhGH) on growth velocity, calcium-phosphorus metabolism, bone mineral density and changes in body composition in children with growth hormone deficiency (GHD)].[Article in Polish]`by Zak T, Basiak A, Zubkiewicz-Kucharska A, Noczyńska A., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20529605), it also works with riboflavin and niacin to improve the digestive system in absorbing vital nutrients.

4. Iron[21] and iron deficiency anemia[22]
Iron is essential for the production of red blood cells and carrying life-giving oxygen to human cells. Deficiency of iron causes anemia, anemia of chronic disease, cough, anemia in pregnancy, etc., leading to reducing blood flow to the reproductive organ according to the study of `The effects of iron deficiency on estradiol-induced suppression of erythropoietin induction in rats: implications of pregnancy-related anemia` by Horiguchi H, Oguma E, Kayama F., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/15784734)


Side effects
1. Because of the presence of botulinum endospores, children under one year of age should not be given honey
2. Honey may be poison if produced from the flowers of oleanders, rhododendrons, mountain laurels, sheep laurel, and azaleas etc.
3. It may contain traces of heavy metals, pesticides, etc.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight


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Sources
(1) HOW TO SUBSTITUTE SUGAR IN YOUR BAKING & FREE SUBSTITUTES CHART! By Gemma Stafford .
(2) Comparison of the enhancement of plasma glucose levels in type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats by oral administration of sucrose or maple syrup by Nagai N1, Ito Y, Taga A.(PubMed)
(3) Relationship between Added Sugars Consumption and Chronic Disease Risk Factors: Current Understanding by James M. Rippe1,2,* and Theodore J. Angelopoulos3(PubMed)
(4) Honey as a source of dietary antioxidants: structures, bioavailability and evidence of protective effects against human chronic diseases by Alvarez-Suarez JM1, Giampieri F, Battino M.(PubMed)
(a) http://www.ncbi.nlm.nih.gov/pubmed/20091616
(b) http://www.ncbi.nlm.nih.gov/pubmed/22050652
(c) http://www.ncbi.nlm.nih.gov/pubmed/21943200
(d) http://www.ncbi.nlm.nih.gov/pubmed/19754926
(e) http://www.ncbi.nlm.nih.gov/pubmed/21982267

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