Wednesday 18 May 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment of Gout due to Damp-Heat in TCM

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.


              


                                              Treatments



In Traditional Chinese medicine perspective
A. Treatment according to TCM assistant in the article of "Chinese herbal formula(s) can treat or relief Gout"(27), in Chinese medicine, gout is a condition of a joint painful wind syndrome caused by
1.  Formula for Damp-Heat induced gout
1.1. Painful obstruction due to the containment of Damp-Heat in the channels of that can lead to acute articular rheumatism, acute attack of gout, arthritis, hot joints, joint pain, tremors, dark urine, etc.
1.2. Chinese Herbal Formula Xuan Bi Tang used to clear and damp-Heat, unblock the Channels, eliminate painful obstruction, etc. Ingredients include
a. Guang Fang Ji (Radix Aristolochiae Fangchi, Aristolochia Root, Stephania) – 15g. -expels damp heat in upper jiao, expels superficial swellings, induces urination
b. Xing Ren (Semen Pruni Armeniacae, Apricot Seed) – 15g. -regulates lung Qi and water metabolism
c. Yi Yi Ren (Semen Coicis Lachryma Jobi) – 15g. -tonify spleen, clear dampness, relieve painful obstructions
d. Can Sha (Excrementum Bombycis Mori, Silkworm Feces) – 9g. -tonify spleen, clear dampness, relieve painful obstructions
e. Ban Xia (Rhizoma Pinelliae Tematae, Pinellia Rhizome) – 9g. -dries dampness, transforms tubidity
f. Lian Qiao (Fructus Forsythiae Suspensae, Forsythia Fruit) – 9g. -clears superficial heat
g. Zhi Zi (Fructus Gardeniae Jasminoidis, Cape Jasmine Fruit, Gardenia) – 9g. -clear heat, drains dampness, induces urination
h. Hua Shi (Talcum, Talcum) – 15g. -clear heat, drains dampness, induces urination
i. Chi Xiao Dou (Semen Phaseoli Calcarati) – 9g. -clears heat, drains dampness, induces urination(281)

Tuesday 17 May 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment in Herbal Medicine - Purple Sweet Potato

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.


              


                                              Treatments


In herbal medicine perspective
5. Purple Sweet Potato
Sweet potato is a large, starchy, sweet tasting tuberous roots vegetable, genus Ipomoea, belongings to the family Convolvulaceae. Its young leaves can be made into a delicious dish in Chinese foods. Some species of batatas are actually poisonous.
Anthocyanin extracts from purple sweet potato in comparison with conventional medicine allopurinol, on serum uric acid levels in hyperuricemic mice, reduced the serum uric acid concentration to 4.10 ± 0.04 mg/dLa single oral dose of 100 mg/kg(279).
Dr. Zhang ZC and colleagues at the Huazhong Agricultural University said, "APSPE could not only inhibit the XO activity in mouse liver, but also reduce the serum uric acid level in hyperuricemic mice and affect the expression of mRNA levels of related renal transporters, such as mURAT1, mGLUT9, mOAT1 and mOCTN2"(280).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

References
(279) Hypouricemic effects of anthocyanin extracts of purple sweet potato on potassium oxonate-induced hyperuricemia in mice by Hwa KS1, Chung DM, Chung YC, Chun HK.(PubMed)
(280) Effects of anthocyanins from purple sweet potato (Ipomoea batatas L. cultivar Eshu No. 8) on the serum uric acid level and xanthine oxidase activity in hyperuricemic mice by Zhang ZC1, Su GH, Luo CL, Pang YL, Wang L, Li X, Wen JH, Zhang JL.(PubMed)

Monday 16 May 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment in Herbal Medicine - Devil’s claw

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.


              


                                              Treatments


In herbal medicine perspective
4. Devil’s claw
Devil's claw also known as wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa,  used as herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidneys conditions, etc.Harpagoside, a Glycoside, the chemical, principle extracted from the Devil’s Claw root, contributes the natural anti-inflammatory properties and used as a Gout remedy and other painful disorders of the musculoskeletal system(274). The major phytochemical harpagoside, as a major iridoid glycoside, exhibited anti-inflammatory and COX inhibitory activity against rheumatism, gout, palsy and amenorrhea(276), according to the National Institute of Pharmaceutical Education and Research.

According to the University of KwaZulu-Natal, Harpagophytum procumbens root may be very effective used in the management and/or control of painful, arthritic and other inflammatory conditions, as well as for adult-onset, type-2 diabetes mellitus as the roots is used exclusive in some communities of South Africa(275).
Furthermore, phytochemical phenylpropanoid glycoside acteoside found in the herb(277) also ameliorated the levels of serum uric acid and hyperuricemic in mice through expression of inhibited mouse liver xanthine dehydrogenase XDH and xanthine oxidase XO activity(278), the Second Military Medical University suggested.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
(274) Devils Claw as a Natural Remedy for Gout By: Betty Roberts
(275) Analgesic, antiinflammatory and antidiabetic properties of Harpagophytum procumbens DC (Pedaliaceae) secondary root aqueous extract by Mahomed IM1, Ojewole JA.(PubMed)
(276) Anti-inflammatory effect of Ajuga bracteosa Wall Ex Benth. mediated through cyclooxygenase (COX) inhibition by Gautam R1, Jachak SM, Saklani A.(PubMed)
(277) New and known iridoid- and phenylethanoid glycosides from Harpagophytum procumbens and their in vitro inhibition of human leukocyte elastase by Boje K1, Lechtenberg M, Nahrstedt A.(PubMed)
(278) Hypouricemic effects of phenylpropanoid glycosides acteoside of Scrophularia ningpoensis on serum uric acid levels in potassium oxonate-pretreated Mice by Huang CG1, Shang YJ, Zhang J, Zhang JR, Li WJ, Jiao BH.(PubMed)


Sunday 15 May 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment In Herbal medicine - Alfalfa

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.


              


                                              Treatments


In herbal medicine perspective
3. Alfalfa
Alfalfa is a flowering plant in the genus Medicago, belongings to the family Fabaceae, cultivated all over the world as hay for cattle feeding. The leaves, sprouts, and seeds has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney and urinary tract infection, etc.

In the article by By jeffwend, the author wrote that Alfalfa can help to increase uric acid levels in the urine which can help reduce the amount of uric acid available to crystallize(270), probably due to the effectiveness of ethyl acetate extracts isolated from the herb in ameliorated production of pro-inflammatory cytokines and alleviate acute inflammatory hazards(271).
Dr. Ferrari FC and colleagues at the Universidade Federal de Ouro Preto, in the investigation of Leaves infusion of Pimenta pseudocaryophyllus (Gomes) Landrum, expressed the inhibition of ethyl acetate extracts in anti-hyperuricemic effects through uricosuric effects and inhibition of xanthine oxidase throughits anti-inflammatory property(272).
The Universidade other study also insisted, "The ethyl acetate, methanolic and aqueous extracts of Sparattosperma leucanthum showed significant results on evaluated models and therefore may be important agents for the treatment of gouty arthritis and hyperuricemia"(273).


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

References
(270) Alfalfa For Gout, Updated on August 24, 2012(Treat and prevent gout with Alfalfa Tablets)
(271) Ethyl acetate extracts of alfalfa (Medicago sativa L.) sprouts inhibit lipopolysaccharide-induced inflammation in vitro and in vivo by Hong YH1, Chao WW, Chen ML, Lin BF.(PubMed)
(272) Effects of Pimenta pseudocaryophyllus extracts on gout: Anti-inflammatory activity and anti-hyperuricemic effect through xantine oxidase and uricosuric action by Ferrari FC1, Lemos Lima Rde C1, Schimith Ferraz Filha Z1, Barros CH1, de Paula Michel Araújo MC1, Antunes Saúde-Guimarães D2.(PubMed)
(273) Effects of extracts of leaves from Sparattosperma leucanthum on hyperuricemia and gouty arthritis by Lemos Lima Rde C1, Ferrari FC1, de Souza MR1, de Sá Pereira BM1, de Paula CA1, Saúde-Guimarães DA2.(PubMed)

Friday 13 May 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment In Herbal medicine - Green tea

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.


              


                                              Treatments


In herbal medicine perspective
2. Green tea
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Epidemiological evidence showed that green green tea process anti cancers and anti progression of numbers of diseases(264), including gout(265)(266)
Epigallo catechin-O-gallate (EGCG), along with its broad bioavailability is considered very attractive as a putative curative drug for various diseases such as dermatosis, gout, atherosclerosis and cancer, through green tea anti-oxidant properties and antagonistic action in some inflammatory(267). processes.
Quercetin, another green tea main component of antioxidant also displays lowered plasma uric acid concentrations significantly, equivalence to in approximately 100 g red onions, for 4 weeks in healthy males(268).
Dr. Jatuworapruk K and colleagues at the Chiang Mai University, insisted," Green tea extract may modestly lower SUA level and decreases uric acid clearance. Green tea extract also significantly elevated serum antioxidant capacity with a positive dosage effect. The effect of GTE on SUA in healthy individuals was short term. The effects of GTE on urate handling in patients with hyperuricemia or gout need to be determined"(269).


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

References
(264) #Healthy #Foods - Green tea - Leaves of Camellia sinensis by Kyle J. Norton
(265) Quercetin lowers plasma uric acid in pre-hyperuricaemic males: a randomised, double-blinded, placebo-controlled, cross-over trial by Shi Y1, Williamson G1.(PubMed)
(266) The association of vitamin C, alcohol, coffee, tea, milk and yogurt with uric acid and gout by Towiwat P1, Li ZG2.(PubMed)
(267) [Multiple actions of EGCG, the main component of green tea].[Article in French] by L'Allemain G1.(PubMed)
(268) Quercetin lowers plasma uric acid in pre-hyperuricaemic males: a randomised, double-blinded, placebo-controlled, cross-over trial by Shi Y1, Williamson G1.(PubMed)
(269) Effects of green tea extract on serum uric acid and urate clearance in healthy individuals. by Jatuworapruk K1, Srichairatanakool S, Ounjaijean S, Kasitanon N, Wangkaew S, Louthrenoo W.(PubMed)





Thursday 12 May 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment In Herbal medicine - Artichoke

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.


              


                                              Treatments
In herbal medicine perspective
1. Artichoke
Apricot tree is classified with the family of the plum belongings to the family Rosaceae with yellow to orange color, often tinged red on the side exposed to the sun.
According to the University of Florida, Artichoke (Cynara scolymus L.) leaves historically used for the treatment of hyperuricemia and gout. In our study the leaves also inhibited the xanthine oxidase (XO) through the efficacy of caffeic acid derivatives and flavones(259) but not  luteolin, and luteolin 7-O-glucoside in animal study(259).
Dr. Caton SJ and colleagues at the joint study led by the University of Leeds, said, "Repeated exposure is known to enhance intake of a novel vegetable in early life but individual differences in response to familiarisation have emerged from recent studies"(260) learning to love artichoke may reduce risk of gout in aging process.
In fact, University of Tokushima study of caffeic acid insisted, The phenolic compounds ameliorated xanthine oxidase (XO) which which is related to several diseases, e.g. gout(262), through its antioxidant activity when comparison to the conventional allopurinol(261).
Further more the flavones found in artichoke exhibited anti xanthine oxidase and/or α-glucosidase effects by remarkedly lowered serum uric acid levels in potassium oxonate induced hyperuricemic mouse(263).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

References
(259) Flavonoids of Cynara scolymus possess potent xanthinoxidase inhibitory activity in vitro but are devoid of hypouricemic effects in rats after oral application by Sarawek S1, Feistel B, Pischel I, Butterweck V.(PubMed)
(260) Learning to eat vegetables in early life: the role of timing, age and individual eating traits by Caton SJ1, Blundell P2, Ahern SM2, Nekitsing C2, Olsen A3, Møller P3, Hausner H3, Remy E4, Nicklaus S4, Chabanet C4, Issanchou S4, Hetherington MM2.(PubMed)
(261) Identification of a potent xanthine oxidase inhibitor from oxidation of caffeic acid by Masuda T1, Shingai Y2, Takahashi C2, Inai M2, Miura Y2, Honda S2, Masuda A3.(PubMed)
(262) Structure-activity relationship of caffeic acid analogues on xanthine oxidase inhibition by Chan WS1, Wen PC, Chiang HC.(PubMed)
(263) Discovery of xanthine oxidase inhibitors and/or α-glucosidase inhibitors by carboxyalkyl derivatization based on the flavonoid of apigenin by Su ZR1, Fan SY1, Shi WG1, Zhong BH2.(PubMed)






Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment In conventional medicine - Intra-articular corticosteroids

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.


              


                                              Treatments

A. In conventional medicine perspective
5. Intra-articular corticosteroids
a. Intraarticular steroid injections are injected directly into an affected joint to improve joint function in patinet with gout. According to the study led by the Flexion Therapeutics, Inc., intra-articular corticosteroids porduced by the company significantly improved histological scores with no adverse effect on the HPA axis, through reduced pathophysiology of multiple joint diseases such as osteoarthritis (OA), RA and gout(256).
Unfortunately, Dr. Wechalekar MD and colleagues at the Repatriation GeneralHospital, suggested, "There is presently no evidence from randomized trials to support the use of intra-articular glucocorticoid treatment in acute gout. Evidence suggests intra-articular glucocorticoids may be a safe and effective treatment in osteoarthritis and rheumatoid arthritis"(257).
b. Side effects are not limit to(258)
b.1. Infection
b.2. Facial flushing
b.3. Local skin atrophy and depigmentation
b.4. Crystalline synovitis
b.5. Allergic reaction
b.6. Uterine haemorrhage
b.7. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

References
(255) ACTH therapy in infantile spasms: side effects by R Riikonen and M Donner(PMC)
(256) Sustained efficacy of a single intra-articular dose of FX006 in a rat model of repeated localized knee arthritis by Kumar A1, Bendele AM2, Blanks RC3, Bodick N4.(PubMed)
(257) Intra-articular glucocorticoids for acute gout by Wechalekar MD1, Vinik O, Schlesinger N, Buchbinder R.(PubMed)
(258) Intraarticular cortisone injection for osteoarthritis of the hip. Is it effective? Is it safe? by David W. Kruse(PMC)