Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - The Misdiagnosis and delay diagnosis

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

           The Misdiagnosis and delay diagnosis

According to the University of Kansas School of Medicine, out of 9,108 consecutive new patients seen in an outpatient rheumatology clinic, 155 (1.7%) diagnosed as having gout, 164 (1.8%) had been incorrectly diagnosed as having gout in the community(131).

"The main factors potentially contributing to delayed diagnosis after consultation included reported misdiagnosis, attacks in joints other than the first metatarsophalangeal joint, and female gender. The limitations in using serum uric acid (SUA) levels for diagnostic purposes were not always communicated effectively to patients, and led to uncertainty and lack of confidence in the accuracy of the diagnosis", the Keele University insisted(134).

1. Rheumatoid arthritis

In elderly, polyarticular gout may be misdiagnosed due to confusing clinical presentation of "diuretic gout" such as polyarticular onset, subacute symptoms. ......According to the Albert Einstein College of Medicine, misdiagnosis of rheumatoid arthritis can induce poor treatment of gout, affecting underlying conditions of renal insufficiency, and cardiac risks(132).

2. Elderly-onset gout (EOG)

Elderly-onset gout (EOG) is a condition of gout with onset at age 65 years or over, shared a relevant epidemiological, clinical and therapeutic differences from the typical middle-age form. According to the University of Ferrara,"EOG has recently been confirmed as the most common inflammatory arthropathy in older people, with important demographic implications and substantial impact on daily clinical practice. Despite the high prevalence, gout, in the elderly, often remains misdiagnosed or diagnosed late in its clinical course."(133).

3. Misdiagnosis due to confusing in classification

According to the Hospital Universitario Cruces, as a step-up disease, gout consists different stages: acute gout, intercritical gout, and chronic gout but in clinical practice, gout should be considered as a single disease with either or both acute (most commonly, episodes of acute inflammation) but not restricted to chronic synovitis in support the clinical manifestations and diagnosis of gout(135).

4. Recurrent gouty arthritis

There is a report of misdiagnosis of recurrent gouty arthritis associated with hyperuricemia and hyperlipidemia during adolescence. as steatohepatitis in a family with mild glycogen storage disease type 1a. National Chung Hsing University, due to the effect of result of misdiagnosis suggested that patients with mild glycogen storage disease should be considered in the adolescents with unexplained hyperuricemia and hyperlipidemia, despite the presence of normal blood glucose levels(136).

5. Chylous cysts of the neck or chest
According to the Geisinger Medical Center, there is a report of chylous cyst was misdiagnosed as recurrent chest wall gouty tophus due to form birefringent crystals upon drying(137).

6. Psoriatic arthritis
In the review of Forty-two patients with psoriatic arthritis who were referred to a tertiary medical center from 1983 to 1987, eight patients with foot and ankle involvement were diagnosed and treated for either gout or compression of a digital nerve due to failure to identify psoriatic skin lesions and the  associate foot and ankle symptoms with psoriatic arthritis.(138).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

References
(130) Dual-Energy Computed Tomography: Advantages in the Acute Setting by McLaughlin PD1, Mallinson P2, Lourenco P2, Nicolaou S2.(PubMed)

(131) The misdiagnosis of gout and hyperuricemia by Wolfe F1, Cathey MA.(PubMed)

(132) Misdiagnosis of rheumatoid arthritis in an elderly woman with gout by Sewell KL1, Petrucci R, Keiser HD.(PubMed)

(133) Elderly-onset gout: a review. by De Leonardis F1, Govoni M, Colina M, Bruschi M, Trotta F.(PubMed)

(134) Mapping patients' experiences from initial symptoms to gout diagnosis: a qualitative exploration. by Liddle J1, Roddy E1, Mallen CD1, Hider SL1, Prinjha S2, Ziebland S2, Richardson JC1.(PubMed)

(135) Clinical manifestations and diagnosis of gout by Perez-Ruiz F1, Castillo E2, Chinchilla SP2, Herrero-Beites AM3.(PubMed)

(136) Misdiagnosis as steatohepatitis in a family with mild glycogen storage disease type 1a by Shieh JJ1, Lu YH, Huang SW, Huang YH, Sun CH, Chiou HJ, Liu C, Lo MY, Lin CY, Niu DM.(PubMed)

(137) Misdiagnosis of a chylous cyst as chest wall gouty tophus: a case of true pseudogout by Adhikesavan LG1, Ayoub WT, Schumacher HR.(PubMed)

(138) Psoriatic arthritis of the foot and ankle: analysis of joint involvement and diagnostic errors by Hammerschlag WA1, Rice JR, Caldwell DS, Goldner JL.(PubMed)

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - The Diagnosis

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                             The Diagnosis

According to the Rockville (MD): Agency for Healthcare Research and Quality (US); 2016 Feb. Report No.: 15(16)-EHC026-EF.AHRQ Comparative Effectiveness Reviews(125).
if you are experience SHARP pain in the joint with visual symptoms of collection of urate crystal deposit and other clinical signs and symptoms of gout, your doctor may order the below tests
1. Joint fluid test 
Withdraw fluid from affected joint to test for sign of urate crystal accumulation for confirmation of gout.

2. Blood test
Blood test is necessary to measure levels of uric acid for gout and creatinine for kidney function in your blood. According to the University of Auckland, measured blood test in people with gout has caused confusion about the details of urate measurement in suboptimal care(126), as the measurement may not be accurate as some some people with high levels of uric acid levels, have never experienced gout. And some people have signs and symptoms of gout, but don't have higher levels of uric acid in their blood(127).

3. X-ray imaging(125)
The aim of the test is to rule other causes of inflammation of joints. In case of negative or inconclusive, other tests such as ultrasound and dual energy CT scan to provide additional information in patients(128),

4. Ultrasound(125)
The aim is to detect any urate crystals deposit in a joint or in a tophus for confirmation of gout when X ray is inconclusive and negative(128). Dr. Codreanu C and Dr. Enache L said, "adding US to the clinical and serological features will significantly improve the sensitivity of proposed criteria. The ability of high resolution US to detect crystalline deposits of monosodium urate in joints and soft tissues is well recognized"(129)

5. Dual energy CT scan(125)
The aim of the test is to detect any any urate crystals deposit in a joint or in a tophus even without sign of acute inflammation. "Dual-energy computedtomography (CT) contributes over conventional single-energy CT,........ Particular emphasis will be placed on acute gout, bone marrow edema, acute renal colic, acute cardiovascular and neurovascular emergencies aswell as characterization of abdominal incidentalomas" according to the joint study led by the University of British Columbia.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

References

(125) Diagnosis of Gout [Internet].Editors Newberry SJ, FitzGerald J, Maglione MA, O'Hanlon CE, Han D, Booth M, Motala A, Tariq A, Dudley W, Shanman R, Shekelle PG.(PubMed)
(126) Urate testing in gout: why, when and how by Dalbeth N1, Winnard D, Gow PJ, Boswell DR, Te Karu L, Lindsay K, Arroll B, Stamp LK.(PubMed)
(127) Tests and diagnosis By Mayo Clinic Staff(127)
(128) Diagnostic imaging of gout: comparison of high-resolution US versus conventional X-ray by Rettenbacher T1, Ennemoser S, Weirich H, Ulmer H, Hartig F, Klotz W, Herold M.(PubMed)
(129) Is ultrasound changing the way we understand rheumatology? Including ultrasound examination in the classification criteria of polymyalgia rheumatica and gout by Codreanu C1, Enache L2.(PubMed)

   

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - The Complication of Advanced gout

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

           
                                   The Complications

5. Advanced gout
Untreated gout may cause even more deposits of urate crystals to form under the skin in nodules called tophi (TOE-fie), leading to advanced gout with tophi developed in several areas, including fingers, hands, feet, elbows,.......Occasionally,untreated gout can lead to advanced arthritic changes. and chronic discomfort of the hallux MTPJ, necessitating surgical intervention to help alleviate symptoms, according to Dr. Balutis E and Dr., Pino A.(123).Refractory gout in patients who have ongoing symptoms of active disease and cannot maintain a target serum urate less than 6 mg/dl were treated successfully with long-term pegloticase treatment, improvements in clinical status, in the form of flare and tophus reduction and maintained goal range urate-lowering responses during up to 2.5 years of additional treatment(124).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(123) Gout Causing Isolated Sesamoid Destruction Mimicking a Neoplastic Process by Balutis E1, Pino A.(PubMed)

(124) Long-term safety of pegloticase in chronic gout refractory to conventional treatment by Becker MA1, Baraf HS, Yood RA, Dillon A, Vázquez-Mellado J, Ottery FD, Khanna D, Sundy JS.(PubMed)

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - The Complication of Recurrent gout

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

              
     The Complications

4. Recurrent gout

Recurrent episodes of gout have shown to induce further damage to joints and other tissues from urate crystal deposition. Certain medication such as aspirin used on two consecutive days is associated with an increased risk of recurrent gout attacks(118). Purine-rich foods intake is associated to increased risk of recurrent gout after 2 days(119).
Consumption of beer, loop or thiazide diuretics, ciclosporin, tacrolimus, ethambutol, pyrazinomide, nicotinic acid, also are found stimulate the progression of recurrent gout, according to Dr. Robin Fox, GP(120). Other risk factors for recurrent gout include medical conditions such as Psoriasis Myeloproliferative disorders, Administration of cytotoxic drugs (tumour lysis syndrome), Inherited enzyme deficiencies and  Lead poisoning(occupations)(120).

Fortunately, in a study of 633 individuals with gout. cherry intake over a 2-day period was associated with a 35% lower risk of gout attacks. Cherry extract intake showed a similar inverse association(121). And according to the University of Maryland School of Medicine, "primary prevention of gout can be achieved through lifestyle changes including weight loss, restricting protein and calorie intake, limiting alcohol consumption, avoiding the use of diuretics in the treatment of hypertension, and avoiding occupational exposure to lead"(122).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(118) Low-dose aspirin use and recurrent gout attacks by Zhang Y1, Neogi T, Chen C, Chaisson C, Hunter DJ, Choi H.(PubMed)
(119) Purine-rich foods intake and recurrent gout attacks by Zhang Y1, Chen C, Choi H, Chaisson C, Hunter D, Niu J, Neogi T.(PubMed)
(120) Management of recurrent gout by Robin Fox, GP1(PMC)
(121) Cherry consumption and decreased risk of recurrent gout attacks by Zhang Y1, Neogi T, Chen C, Chaisson C, Hunter DJ, Choi HK.(PubMed)

(122) Prevention and management of gout by Star VL1, Hochberg MC.(PubMed)

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - The Complication of Joint damage

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                   The Complications

3. Joint damage
Acute gout or acute gouty arthritis can induce joint damage thoough deposit of uric acid crystals in joint spaces. Patients with gout are associated to complication of joint damage, according to the joint study led by University of Auckland, monosodium urate crystals are frequently present in joints affected by radiographic damage in gout(115).
Dr. Dalbeth N and professors at the University of Auckland in the review of joint damage in aptients with gout, suggested that intensive urate-lowering therapy plays a critical role in improvement in structural damage, particularly bone erosion(116).

MDHAQ (Multidimensional Health Assessment Questionnaire) scores for physical function (FN), pain, Patient Global Estimate (PATGL), and RAPID3 (Routine Assessment of Patient Index Data, a composite of these 3 measures) in the examination of patients with osteoarthritis, systemic lupus erythematosus, spondyloarthropathy, and gout, similarly to rheumatoid arthritis suggested an improvement scores in patients with 5 diagnoses, according to NYU Hospital for Joint Diseases,(117).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(115) Relationship between structural joint damage and urate deposition in gout: a plain radiography and dual-energy CT study by Dalbeth N1, Aati O1, Kalluru R1, Gamble GD1, Horne A1, Doyle AJ2, McQueen FM3.(PubMed)
(116) Exploratory study of radiographic change in patients with tophaceous gout treated with intensive urate-lowering therapy by Dalbeth N1, Doyle AJ, McQueen FM, Sundy J, Baraf HS.(PubMed)
(117) MDHAQ/RAPID3 to recognize improvement over 2 months in usual care of patients with osteoarthritis, systemic lupus erythematosus, spondyloarthropathy, and gout, as well as rheumatoid arthritis by Castrejón I1, Bergman MJ, Pincus T.(PubMed)

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - The Complication of Kidney stone

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                   The Complications

2. Kidney stone
Kidney stone is a composed of mineral salts formed in the kidneys. Men account for the 80% of those with kidney stones and are at risk of the forming between 30 and 40 years of age. About 75% of kidney stones are calcium stones.

Minimally surgical intervention depends on performing the least invasive technique with the highest success of stone removal, according to Harvard Medical School(107). Others suggests that flexible ureterorenoscopy may be the first-choice treatment for stones <2cm(108).

Dr. Ahmed MH and colleagues at the Milton Keynes Hospital NHS Foundation Trust, believe that Renal stone disease and gallstone disease are the widely prevalent renal stone disease and gallstone disease across the globe, are associated with a variety of diseases including gout(110).

In a total of 396 male patients with gout and 403 age- and sex- matched healthy controls included in this study conducted by the Affiliated Hospital of Qingdao University, risk of renal calculus is increased in patient carrying the TT genotype of CARD8 rs2043211 polymorphism with gout(109).

Recent study by some well known institution suggested that the combination of Green tea(111), Grape (112) and Sweet Potato(113) smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of  kidney Stones  without inducing adverse effects.

If you need more information of the above smoothie, please visits, The Best Smoothie of Green tea, Grape and Sweet Potato for Prevention and Treatment of Kidney Stones caused by Medullary sponge kidney(114).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(107) Minimally invasive surgical treatment for kidney stone disease by Rodríguez D1, Sacco DE2.(PubMed)
(108) Current practice in Latin America of flexible ureterorenoscopy with laser for treating kidney stones responses on a Latin American questionnaire[Article in English, Spanish] by Manzo BO1, Bertacchi M2, Lozada E3, Rasguido A4, Aleman E5, Cabrera M6, Rodríguez A7, Manzo G3, Sánchez H3, Blasco J8.(PubMed)
(109) CARD8 rs2043211 polymorphism is associated with gout in a Chinese male population by Chen Y1, Ren X, Li C, Xing S, Fu Z, Yuan Y, Wang R, Wang Y, Lv W.(PubMed)
(110) The association between renal stone disease and cholesterol gallstones: the easy to believe and not hard to retrieve theory of the metabolic syndrome by Ahmed MH1, Barakat S, Almobarak AO.(PubMed)
(111) Effects of green tea on urinary stone formation: an in vivo and in vitro study by Jeong BC1, Kim BS, Kim JI, Kim HH.(PubMed)
(112) 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model by Lee HJ1, Jeong SJ, Lee HJ, Lee EO, Bae H, Lieske JC, Kim SH.(PubMed)

(113) Vitamin E therapy prevents hyperoxaluria-induced calcium oxalate crystal deposition in the kidney by improving renal tissue antioxidant status by Thamilselvan S1, Menon M.(PubMed)

(114) The Best Smoothie of Green tea, Grape and Sweet Potato for Prevention and Treatment of Kidney Stones caused by Medullary sponge kidney by Kyle J. Norton

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Diseases associated with Gout - Psoriasis

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                   Diseases associated with  Gout

According to the UK Gout Society,  diseases associated to gout may include

12. Psoriasis  
Psoriasis is an autoimmune diseases induced abnormal skin path with expression of redness, itchy, and scaly. According to the joint study led by the University of Trieste, the increased incidence of a large number of diseases which share an inflammatory origin probably due to the pro-inflammatory cytokine spillover from active psoriatic lesions leading to a large inflammation on distant tissues(95).

Methotrexate, a conventional medicine may be an effective therapy for extensive and severe forms of psoriasis if patients are selected carefully and monitored regularly in the dose of <15-20 mg/week(96) Dr. Haustein UF and Dr. Rytter M. insisted(96).

According to the joint study led by the Brigham and Women's Hospital and Harvard Medical School, Boston, individuals with psoriasis have increased blood levels of uric acid. In the documented 2217 incident cases of gout during follow-up. Psoriasis was associated with an increased risk of subsequent gout with a multivariate HR of 1.71(97).

Dr. Lai YC and Dr.Yew YW said, " A raised serum uric acid level may be a consequence of metabolic syndrome, which in turn is associated with psoriasis"(98).

Recent studies by some renowned institutions suggested that green tea(99) and grape(100) may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of psoriasis.

If you need more information of the above smoothie, please visits, The Unbelievable Smoothie Green Tea and Grape for reduced risk and Treatment of Psoriasis(101).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(95) Increased airway inflammation in patients with psoriasis by Damiani G1, Radaeli A2, Olivini A2, Calvara-Pinton P3, Malerba M2.(PubMed)
(96) Methotrexate in psoriasis: 26 years' experience with low-dose long-term treatment by Haustein UF1, Rytter M.(PubMed)
(97) Psoriasis, psoriatic arthritis and risk of gout in US men and women by Merola JF1, Wu S2, Han J3, Choi HK4, Qureshi AA5.(PubMed)
(98) Psoriasis and uric acid: a population-based cross-sectional study by Lai YC1, Yew YW2.(PubMed)
(99) Green tea protects against psoralen plus ultraviolet A-induced photochemical damage to skin by Zhao JF1, Zhang YJ, Jin XH, Athar M, Santella RM, Bickers DR, Wang ZY.(PubMed)

(100) Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice by Kjær TN1, Thorsen K2, Jessen N2, Stenderup K3, Pedersen SB1.(PubMed)

(101) The Unbelievable Smoothie Green Tea and Grape for reduced risk and Treatment of Psoriasis by Kyle J. Norton