Food Therapy: Fennel In Attenuated Risk, Progression and Treatment of Irritable Bowel Syndrome

Kyle J. Norton


Herbal fennel may have a strong implication in reduced risk and treatment of irritable bowel syndrome, some scientists postulated.

Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
19. Etc.

Irritable bowel syndrome is a common digestive disorder, affecting the function of the large intestine.

According to the statistic, approximately 10 -15% of world population are infected by the disease, depending to geographic variation.

According to the study of 121 patients with mild-to-moderate symptoms of IBS defined by an Irritable Bowel Syndrome- symptom severity score (IBS-SSS) 100-300 and abdominal pain score 30-70 on a 100 mm Visual Analogue Scale (VAS), randomly assigned to Curcumin-Fennel (CU-FEO) or placebo (2 capsules b.d. for 30 days), treatment group demonstrated a significant effect in decreased mean scores observed by the relative IBS-SSS and the pain score in compared to placebo group.

In the over all performance, intake of CU-FEO group showed a incredible improvement of all symptoms with the percentage of symptom-free patients significantly higher of 26 % in compared to 7% the placebo group, particularly, in all domains of IBS-quality of life(QoL), without inflicting any side effect.

Furthermore, in the period of experiment, curcumin + fennel treatment displayed a progressive decrease in intensity and a greater proportion of patients in reporting ≥50% reduction in abdominal pain.

In the length of the experiment, treated group expressed  a substantial improvement of health-related QoL observed through the reduced use of health resources and increased work productivity, progressively in compared to the baseline taken before the treatment.

Dr. Portincasa P, the lead author after taking into account of other co founders, said, "CU-FEO was safe, well-tolerated and induced symptom relief in patients with IBS" and " CU-FEO significantly improved symptoms and quality of life in IBS patients over 30 days".

Some researchers suggested that the efficacy of fennel in reduced symptoms of irritable bowel syndrome was possibly associated to the the major chemical component anethole of fennel oil seeds in exerting relaxant effect on intestinal smooth muscle, similar to those medicine used as neurotransmitter dopamine in inhibited the spasmodic activity in facilitation of abdominal pain. 

Moreover, application of fennel also expressed a strong impact on bowel symptoms through orchestrated intestinal inflammation and immune activation against onset and progression of the disease. 

Injection of anethole in vitro and vivo parameters of chicken immunity during experimental avian coccidiosis exerted an important modulation of the immune mediators interleukin-6 (IL6) in  response to infection and tissue injuries and contribution to host defense; interleukin-8 (IL8) in stimulated production of neutrophils, basophils, and T-cells during the inflammatory process; interleukin-10 (IL10), an anti inflammatory factor which plays a critical role in reduced over expression of proinflammatory cytokines in precipitated cells damage and cells death and tumor necrosis factor ligand superfamily member 15 (TNFSF15) in response to acute and chronic inflammation by induced the development of the new blood vessel to promote the site of infection.

These result addressed an impression of fennel anethole effect in improved symptoms and quality of life of patients with IBS through inhibited the increased number of inflammatory cells in the colonic and ileal mucosa activated by low-grade intestinal inflammation

The low-grade inflammation in the pathophysiology of irritable bowel syndrome accompanied with microscopic and molecular abnormalities in large subset in patients today has been focused by some scientists in searching for new conventional treatment for the disease through designed clinical trials for drugs that target this pathophysiologic mechanism.

Taken together, fennel with major bioactive compound anethole may be considered as a functional food and secondary therapy in reduced risk and progression and used combination with conventional medicine for treatment of irritable bowel syndrome

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN

Arthritis Is Curable

You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome by Portincasa P1, Bonfrate L2, Scribano ML3, Kohn A3, Caporaso N4, Festi D5, Campanale MC6, Di Rienzo T6, Guarino M4, Taddia M5, Fogli MV7, Grimaldi M7, Gasbarrini A6.(PubMed)
(2) Immune effects of dietary anethole on Eimeria acervulina infection by Duk Kyung Kim, Sung Hyen Lee, Hyun Lillehoj and David Bravo(Research Gate)

Alternative Therapy: Yoga Intervention in Enhanced Fertility in Couple Diagnosed with Unexplained Causes of Infertility

Kyle J. Norton 

Yoga intervention may be used as an integrated form of exercise in enhanced pregnancy in infertile couple, particularly in women diagnosed with unexplained cause of infertility, some scientists suggested.

Infertility is condition characterized by inability of a couple to conceive after 12 months of unprotected sexual intercourse,  affecting over 5 millions couple alone in the U.S.and many times more in the world

Yoga, the acient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the examine of  a total of 38 year-old woman with infertility of unknown origin with failure of 18 conventional fertility treatments in 5 different fertility centers and 3 different countries with several complications admitted to an Ayurvedic outpatient clinic, researchers found that yoga used combination with other techniques in Ayurveda expressed a higher likelihood of pregnancy.and giving birth of healthy baby.

After  taking into account of other con founders, Dr. Kessler C, the lead author said, " Ayurveda may be a useful complementary option in the case of fertile conventional treatment attempts in female infertility".

Indeed, yoga intervention in improvement of fertility has been found to associate to various fronts involving several implications.

Yoga relaxation and meditation reduced stress showed to
* Enhance sexual desire through stimulated secretion of testosterone hormone
* Bring back the presence by letting go of event causing stress or dealing the stress in the profound way.

These results increased the natural state of awareness of expected mother and father in change of life style and healthy eating which have a strong impact in the stimulated the gastrointestinal function in absorbed nutrients, respiratory system in provided oxygen and circulatory systems to move blood to uterus for conception.
In Men, the moving blood to the reproductive organ enhanced normal sperm count and sperm quality
for making readiness of egg fertilization.

In women, the reduced stress and calming the central nervous system also reduced production of stress hormone in alternated the menstrual cycle expression.

 In other words, yoga intervention restored the secretion hormones in each stage of menstrual in initiated egg release eggs, each month from the ovaries.

Some researchers explained that stress induced production of adrenaline, catecholamines and cortisol, which can inhibit the release GnRH (gonadotropin releasing hormone) in responsible for the release of sex hormones in produced luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the pituitary gland in facilitated the gonads to release sex hormones.

In the support of the above illustration, Dr. Khalsa HK suggested that yoga can help women who experience the challenges of infertility by increasing the clarity of the mind and maintaining healthy body chemistry and connected and balanced the mind and the body in awareness of feel better about the body itself, and begins to treat the body with more respect, particularly in keeping patients positive and patience to undergo the rigors of infertility treatments in conventional medicine.

The study also indicated that infertile women understanding of above implications may lead to healthier lifestyle habits as well as increased sensitivity regarding symptoms and body processes.

Truly, according to the study by the McGrill University, yoga showed a positive effect in treating psychological symptoms such as fear, anxiety and depression and improving the overall quality of life in IVF patients, through letting go of the stress  in the study of 49 infertile women recruited to participate in a 6-week Yoga class during 2013 while awaiting their IVF treatment

And, in the impact of lifestyle modifications, diet, and vitamin supplementation on natural fertility, the University Hospitals/ Case Western Reserve School of Medicine study also agreed that change of life style habit such as smoking and alcohol, maintained weight loss are important features in lower the risk of infertility.  Yoga practice in reduced the psychological aspects may also be helpful in increased chance of fertility, particularly in unexplained cause of women infertility.

The evidence findings suggested that yoga can be used as an integrated form of exercise in enhanced fertility in both men and women through maintaining positively physical and psychological attitude, particularly in women.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Authorbiography
Kyle J. Norton 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) The Effect of a Complex Multi-modality Ayurvedic Treatment in a Case of Unknown Female Infertility by Kessler C1, Stapelfeldt E, Michalsen A, Kowalcek I, Kronpaß L, Dhruva A.(PubMed)
(2) Yoga: an adjunct to infertility treatment by Khalsa HK1.(PubMed)
(3) The impact of lifestyle modifications, diet, and vitamin supplementation on natural fertility by Collins GG1, Rossi BV1.(PubMed)
(4) A prospective study using Hatha Yoga for stress reduction among women waiting for IVFtreatment by Oron G1, Allnutt E2, Lackman T2, Sokal-Arnon T2, Holzer H2, Takefman J3.(PubMed)(5) Stress and the female reproductive system by Kalantaridou SN1, Makrigiannakis A, Zoumakis E, Chrousos GP.(PubMed)

Herbal Therapy: Green Tea and its Bioactive Polyphenol EGCG in Reduced Risk, Progression and Treatment of Psoriasis and Initiation of Psoriatic Arthritis

Kyle J. Norton 

Green tea may have a therapeutic and positive effect in reduced risk, progression and treatment of psoriasis, some scientists suggested.

Psoriasis is a immuno-inflammatory disease characterized by speeding up the life cycle of skin cells to induce skin cells to build up rapidly on the surface.

Green tea is a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.

In the investigation of green tea EGCG effect on BALB/c mice induced psoriasis by topically treated with imiquimod (IMQ) for 6 consecutive days, as a psoriasis mouse model, researchers found that application of green tea bioactive compound demonstrated a significant effect in improved psoriasiform dermatitis, and the skin pathological structure by inhibited the proliferating cell nuclear antigen (PCNA) which has been found in elevated levels in patient with psoriasis.

The levels of proliferating cell nuclear antigen (PCNA) considered as a bio marker and a abnormal proliferating cell pool in patient with skin cancer was also inhibited by EGCG injection

Administration of EGCG promoted caspase-14 expression which has been altered in patients with psoriasis to orchestrate epidermal differentiation in decreased in inflammatory lesions in atopic dermatitis through its function as a novel regulator of skin cell differentiation and skin barrier formation to protect the skin cell against inflammation.

Treatment of EGCG also attenuated skin inflammation through reduced levels of inflammatory factors such as interleukin (IL)-17A, a pro-inflammatory cytokine, produced by a group of T helper cell and IL-17F a pro inflammatory cytokine and immune mediator in trigger the innate immune activity in the acute phase of infection.

Furthermore, injection of green EGCG also inhibited the T helper (Th) cell subsets IL-22 in secreted cytokines in stimulated immune the defense against certain microbes and the development and maintenance of chronic inflammatory diseases and IL-23 in enhanced the expansion of T helper type 17 (Th17) cells which has been found to associate to prevalence of many of the inflammatory autoimmune responses, including psoriasis.

Significantly, green tea also reduced infiltrations of T cells in facilitate inflammatory skin lesions caused by injection of imiquimod (IMQ).

Moreover, EGCG also ameliorated the production of malondialdehyde (MDA), an end product of lipid peroxidation in plasma obsevered by the protocol with colorimetric Diagnostic Reagent Kit an indication of over production of reactive oxygen species (ROS) in precipitated free radical chain reaction to induced oxidative stress caused by psoriasis through expression of its antioxidants and induced production of natural antioxidants in the body.

Importantly, the application of green tea compound increased percentages of CD4+ T cells in immunocytes in activated a series of local immunologically mediated stimulatory events that produce further T cell activation and appearance against triggers conversion of symptomless (PN) skin into psoriatic plaques (PP skin).

Dr. Shuangshuang Zhang, the lead author after taking into account of other con founder said, " (
EGCG attenuates the IMQ-induced histological changes of skin) of marked hyperkeratosis, parakeratosis, modest acanthosis, elongated rete ridges, and modest dermal inflammation.... , increased parakeratosis, acanthosis and inflammatory cell infiltration (caused by IMQ)".

EGCG exerted anti-inflammatory, immune regulatory and antioxidant effects in ameliorated expression of psoriasis may also have strong implication in prevented psoriasis in induction of chronic inflammation of the joint in catalyzed psoriatic arthritis.

Taken together, green tea and its bioactive polyphenol EGCG may be considered as a function food for reduced risk, progression and used with conventional medicine for treatment of psoriasis. However, intake of green tea supplement should be taken with exceptional care as acute liver toxicity was reported in several medical literature.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women 

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice by Shuangshuang Zhang,#1 Xiangdong Liu,#2 Lihong Mei,1 Hongfeng Wang,1 and Fang Fang(PMC)

Galectins, The Lower Invertebrates' Lectins as Biomakers and Treatments of Head and Neck Cancer

Kyle J. Norton

Galectin, a family of evolutionary conserved animal lectin found in lower invertebrates to mammals may have a protective and potential effect in reduced risk and treatment of head and neck cancer and acted as biomakers through their binding specificity for β-galactoside sugars activity, some scientists opinionated.

Head and neck cancer (HNSCC) is medical condition characterized by irregular cell growth in the tissue of the mouth, nose, throat, larynx, sinuses, or salivary glands. At the later stage, the cancerous cells can travel a distance away to infect other healthy tissues and organs.

According to the statistic, risk of the cancer  increases with age and are most common in patients between 50 and 70 years old.

In the study of the effect of  in contribution of the prevalent risk of head and neck squamous cell carcinomas (HNSCCs), researchers found that application of galectins express a significant effect in reduced head and neck incidence through inhibited cell proliferation, induced cell death, and cell migration and in the modulation of various functions of the immune system.

Galectins's derivative galectins 1, with function as a key player in a novel stromal regulatory reaction  inhibited abnormal formation and expansion of cancer through deregulation of the multiple signaling pathways and displayed a strong activity in driving immune evasion in tumor site.

Application of galectins also exerted a strong effect in inhibition of tumors cell growth and differentiation and demonstrated a strong effect in altered in some tumors with aggressive phenotype.

Interestingly, in further observation of the immunoblotting, and immunohistochemical analysis, galectins, carbohydrate-binding proteins may have a potential to act as biologic and differentiation markers in HNSCC.

In fact, galectin-1 and galectin-3, the galectins family derivatives were found to associate closely in most HNSCC cell lines and primary tumor specimens, in the evaluation of the effects in 14 HNSCC cell lines and four primary tumor specimens.

Precisely, galectin-1 expression was detected in the basal layer of normal adjacent mucosa, in connective tissue stroma, and at the periphery of invasive tumor islands and  galectin-3 localized to superficial mucosal layers, and adjacent to keratin pearls in invasive carcinoma.

In other words, Galectins localized to the cell surface demonstrated a significant activity in regulated HNSCC tumors in expression of cancer cell cellular process, including induction of cell apoptosis.

Dr. Gillenwater A, the lead author after taking account of other con founders said, "The expression pattern of galectins appears to be associated with degree of squamous differentiation, suggesting a potential role for galectins as biologic and differentiation markers in HNSCC".

Additionally, the study to investigate whether an increase in malignancy level is accompanied by significant modifications of the expression of galectin-1, galectin-3, and Thomsen-Friedenreich antigen (T antigen) as well as the expression of binding sites for these three markers in head and neck squamous cell carcinomas (HNSCCs) indicated that the epithelial tissues in HNSCC exhibited very significantly (P < 0.01 to P < 0. 0001) lower amounts of galectin-1, galectin-3, and T antigen and their respective binding sites in compared to normal counterparts.

The expression of the biomakers indicated above in tumors of the larynx differed very significantly in compared to all the other tumor types.

A loss of differentiation in the HNSCCs is accompanied first by the loss of expression of galectin-3 and galectin-3-reactive sites and then by that of the T antigen and its binding site(s). 

The loss of only galetins 3 expression is also an indication of distinguished the negative lymph node from the positive lymph node HNSCCs

T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation.

Over expression of galectin-# has been found to involve in numerous degenerative processes within the body, including cancer proliferation/ metastasis, heart failure, chronic inflammation, fibrosis and related organ failure.

After summarizing the expression of galetecins and its derivative in tumor aggression, Dr. Choufani G, the lead scientists said, "The decrease in the extent of expression of galectin-3 and galectin-3-reactive sites, T antigen and T antigen-binding sites, and, to a lesser extent, galectin-1 and galectin-1-reactive sites correlates significantly with an increasing level of clinically detectable HNSCC aggressiveness".

The information findings suggested that galetecins, a family of evolutionary conserved animal lectins not only have a therapeutic effect in reduced risk and treatment of head and neck cancer and may be considered as biomaker in determined the aggressiveness, stage and grade of the tumor site.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Galectins as modulators of tumor progression in head and neck squamous cell carcinomas by Saussez S1, Camby I, Toubeau G, Kiss R.(PubMed)
(2) Expression of galectins in head and neck squamous cell carcinoma by Gillenwater A1, Xu XC, el-Naggar AK, Clayman GL, Lotan R.(PubMed)
(3) The levels of expression of galectin-1, galectin-3, and the Thomsen-Friedenreich antigen and their binding sites decrease as clinical aggressiveness increases in head and neck cancers by Choufani G1, Nagy N, Saussez S, Marchant H, Bisschop P, Burchert M, Danguy A, Louryan S, Salmon I, Gabius HJ, Kiss R, Hassid S.(PubMed)

Food Therapy: Lentil Lectins in Optimization of Immune Function Against Pathogens

Herbal Therapy: Green Tea and Its Bioactive (-)-epigallocatechin-3-gallate (EGCG) in Attenuated Risk and Treatment of Nasal Polyps

Kyle J. Norton 

Green tea may have a therapeutic and positive effect in reduced risk and treatment of stomach polyps, some scientists suggested.

Green tea, is a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.

Nasal polyps are small clump of cells that form on the inside lining of tissue of nasal passages or sinuses. In most cases, the development do not exhibit any symptom to the patients.

In the evaluation of The anti oxidative effects of major catechin from green tea is (-)-epigallocatechin-3-gallate (EGCG) on nasal polyps, chronic inflammatory conditions characterized by myofibroblast differentiation and extracelluar matrix accumulation, researchers at the Korea University College of Medicine found that application of the bioactive compound at dose of concentrations of 10-20 µg/mL demonstrated a strong activity in inhibition of the expressions of α-smooth muscle actin (αSMA) used to identify pathologic fibroblasts such as polyps and plays a role in fibroblast contractility and collagen type I mRNA in contribution to over expression of collagen biosynthesis.through reduced α-SMA and collagen protein levels.

At the same concentration, green tea is (-)-epigallocatechin-3-gallate (EGCG) inhibited expression of TGF-β1 in exhibited nasal polyp cells profileration through cytotoxitic activity caused by reactive oxygen species (ROS) in initiated free radical chain reaction and production.

Dr. Kang JS,  the lead author said," the possibility that EGCG may be effective at inhibiting the development of nasal polyps through an anti-oxidant effect".

Additionally, the examine of the inhibitory effects of epigallocatechin-3-gallate (EGCG) on the synthesis of hypoxia-induced vascular endothelial growth factor (VEGF) in nasal polyp fibroblasts (NPFs)also agreed that application of green tea activated antioxidant expression in inhibited nasal polyp fibroblasts through suppressed production of VEGF via the level of hypoxia-inducible factor (HIF-1)α in respond to decreases in available oxygen in the cellular environment induced by cobalt chloride.

Vascular endothelial growth factor (VEGF) is a protein with function in promoted production of new blood vessel to provide nutrient and oxygen to nasal polyp fibroblasts to facilitate abnormal cell growth activated by hypoxia-inducible factor (HIF-1)α.

Further differentiation also found that combined administration of Foligomycin (a specific HIF-1 alpha inhibitor) and EGCG expressed a more profound inhibition of VEGF synthesis in compared to oligomycin or EGCG treatment alone. 

After taking into account of other con founders Dr. Lin SK, the lead author at the National Taiwan University Hospital said, "Nasal polyp fibroblasts contribute to the pathogenesis of nasal polyps by producing VEGF to promote angiogenesis under hypoxic conditions. Epigallocatechin-3-gallate substantially diminishes HIF-1 alpha and VEGF synthesis in NPFs".

In transforming growth factor beta 1 or TGF-β1 a secreted protein that performs many cellular functions, stimulated nasal polyp fibroblasts (NPFs) proliferation treated with or without EGCG, showed that application of green expressed an impressive effect in inhibited TGF-β1 activities in activation of α-smooth muscle actin (α-SMA) in initiated fibroblast contractility and migration, NADPH oxidase-4 (Nox-4) in stimulated over production of reactive oxygen species, intracellular superoxide and type I collagen production in developed nasal polyp-derived fibroblasts.

The findings suggested that green tea EGCG may be an effective in inhibited development and growth of nasal polyps through its antioxidant activities.

Taking altogether, green tea with major bioactive (-)-epigallocatechin-3-gallate (EGCG) may be considered as function food in reduced risk and treatment of polyps without inducing adverse effects. However, intake of green tea extract should be taken with special as acute liver toxicity has been reported in numbers of case.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women 

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Epigallocatechin-3-gallate inhibits collagen production of nasal polyp-derived fibroblasts by Kang JS1, Park IH, Cho JS, Hong SM, Kim TH, Lee SH, Lee HM.(PubMed)
(2) Hypoxia-stimulated vascular endothelial growth factor production in human nasal polyp fibroblasts: effect of epigallocatechin-3-gallate on hypoxia-inducible factor-1 alpha synthesis by Lin SK1, Shun CT, Kok SH, Wang CC, Hsiao TY, Liu CM.(PubMed)
(3) Green Tea Extract, (-)-epigallocatechin-3-gallate, Inhibits TGF-β1-stimulated Collagen Expression in Nasal Polyp Fibroblasts by H. Park, J. Cho, J. Kang, I. Park, H. Lee(The Journal of Allergy and Clinical immunology)

Alternative Therapy: Yoga Intervention In Prevented Risks and Complications in Pregnancy

Kyle J. Norton 

According to the published literature on PubMed, yoga, a home base exercise may have a positive and profound effect for a healthy and outcome in pregnancy.

Yoga, the ancient practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to ascertain the opinions, practices and knowledge about exercise, including yoga, during pregnancy, researchers after carefully examine the returned surveys, researchers indicated that exercise during pregnancy is considered as a most beneficial, particular pregnancy but 83% felt it was beneficial to start prior to pregnancy and yoga is considered as one of the home base exercise with progressive results.

Interestingly, observation based on BMI, also expressed that the rate of attending yoga lessons was substantially higher in non obese of 65% in compared to obese subjects.

Most women taking yoga therapy believed it is beneficial, and 40% of this group had attempted yoga before pregnancy.

Truly, yoga relaxation and meditation reduced the maternal stress by balanced and connected the mind and body, thus
* reducing risk of vessel tension or maternal hypertension through nitric oxide, is released by endothelial cells and inhibited production of vessel dilation hormones such as norepinephrine and epinephrine with over expression of  numbers of  beta-2 receptors.

* Bring back the presence by letting  go of event causing stress or dealing the stress in the profound way. There results increased the natural state of awareness of motherhood with love and care to the baby in change of life style and healthy eating which may have a strong impact in the stimulated the gastrointestinal function in absorbed nutrients, together with oxygen in the blood  to provide the normal growth and healthy of the baby. The orchestration of the mother facilitated a significant impact in decreasing many complications, including preeclampsia, gestational diabetes (GDM) and intrauterine growth restriction (IUGR), preterm birth,.....

Additionally, yoga by relaxed the central nervous system through reduced stress may also decreased production of prostaglandins in initiated uterus muscle contraction in contributed embryonic and fetal expulsion.

Yoga intervention also improved the immune response in ameliorated risk of intrauterine and uterus infection through stimulated production of antioxidants produced by the body and food intake in fighting against bacterial and viral invasion passing through the vagina and the cervix, the amniotic cavity to the fetus.

The activation of immune activities also protected the baby during the acute phase of infection by regulating production of anti inflammatory mytokines and pro inflammatory cytokines in ameliorated symptoms of inflammation without affecting the function of the immune function in protection of the body against foreign invasion in the infectious site.

Some researchers suggested that yoga intervention reduced stress also have a profound effect in inhibited nervous system sympathetically in production of hormone catecholamines to induce cytotoxic free radicals formation through induction of over production for antioxidants from healthy food sources and natural antioxidants from the body.

By review the information findings, it is safe to suggested that yoga practice may be beneficial physically and psychologically to both mother and the baby.

These results were supported by the review of literature published on 4 databases between January 2004 to February 2014 which indicated that yoga intervention demonstrated lower incidences of prenatal disorders (p ≤ 0.05), and small gestational age (p < 0.05), lower levels of pain and stress (p < 0.05), and higher score of relationship (p < 0.05), particularly in women with high-risk of depression or experienced lumbopelvic pain.

Dr. Jiang Q, the led author said, "yoga is a safe and more effective intervention during pregnancy".

And the Eastern Virginia Medical School in a study to evaluate the peripartum outcomes of yoga during pregnancy, including the postpartum period and lactationm based on review literature on PubMed database from January 1970 to January 2011, suggestion of yoga displayed a significant reduction in rates of preterm labor, intrauterine growth retardation, low birth weight, pregnancy discomforts, and perceived sleep disturbances and practicing yoga during pregnancy can significantly lower pain and discomfort perceived stress and improved quality of life in physical domains.

Taking together, in compared to other forms of therapy, yoga may be one of the safe and most effective in prevented risks, complications and enhanced birth outcome in pregnancy.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Exercise and yoga during pregnancy: a survey by Babbar S1, Chauhan SP.(PubMed)
(2) Effects of yoga intervention during pregnancy: a review for current status by Jiang Q1, Wu Z2, Zhou L1, Dunlop J3, Chen P1.(PubMed)
(3) Yoga during pregnancy: a review by Babbar S1, Parks-Savage AC, Chauhan SP.(PubMed)