Food Therapy: Common (Dried) Peas In Stimulated Immunomodulating Expression

Kyle J. Norton


Intake of common (dried) peas daily and regularly may have a potential effect in enhanced immunomodulating activity, scientists at some renowned institute studies suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Immunomodulation is an action with profound and positive effect in regulated immune response and function through activation of antibody formation or the inhibition of white blood cell activity.

In the evaluation of 173 LAB strains, including the strain NTM048 isolated from green peas having ability to induce IgA production using murine Peyer's patch cells, researchers at the Ishikawa Prefectural University, after taking account of other con founders suggested that

1. Strain NTM048 isolated from green peas demonstrated a higher immunomodulating activiy in compared to other straits.

2. The green pea strait also is well tolerated in gastrointestinal digestion and produce large amounts of exopolysaccharides, a high-molecular-weight polymers which has been used in conventional medicine for prospect of anticoagulant, antithrombotic, immunomodulation, anticancer and as bioflocculants.

3. Application of the strait also induced a significant increase in the faecal IgA content and plasma IgA levels in response to immunogen of BALB/cA mice

Further analysis of the function of strait isolated from green pea, researchers emphasized that the strait have a significant impact in stimulated immunomodulating activities through regulating the transforming growth factor-β in secretion of inflammatory cytokins which play an important role in control of cell growth, cell proliferation, cell differentiation and apoptosis.

The action of the strait in activation of immunomodurating activity was also attributed by stimulating Peyer's patch cells which are aggregated in lymphoid nodules, formed an important part of the immune system.

The information findings prompted Dr. Matsuzaki C, the lead author to suggested, "Strain NTM048 stimulates Peyer's patch cells to induce intestinal and systemic immune response, revealing the potential of NTM048 as a probiotic for enhancing the mucosal barrier function".

The collective information of NTM048 as a probiotic may be helpful to reduce symptoms and treatments of people with digestive disorder by including portions of green peas or dried peas in their daily diet.

Additionally, but in other field of study, researchers at the University of Ottawa launched an investigation of immunomodulating activity of enzymatic protein hydrolysates of yellow pea using in a murine model indicated that

1. Oral administration of Pea protein hydrolysate, after a 12 h pre-treatment, showed a significant inhibition of free radical NO production by activating increased mobile white blood cell by 20%.

The reduction of ROS may be a result of over expression of antioxidant production in stimulated immunomdulqating effect to protect against localized tissue and injure against infection and inflammation caused by foreign pathogens.

2. The injection also showed a strongly inhibited secretion of pro-inflammatory cytokines, TNF-α- and IL-6,in a range of 35 and 80%, respectively.

TNF-α, Tumor necrosis factor is a protein with function in initiated response in the acute phrase of inflammation

IL-6 (Interleukin 6) secreted by immune system to stimulate immune response, is an interleukin with duo functions in promoted either pro and anti inflammatory cytokins or mytokins respectively.
The inhibition of pro inflammatory substance of the pea protein may have a potential effect in reduced symptoms and complications such as reddened, swollen, hot, and often painful in the location of injury or infection.

3. The protein also stimulated the gut mucosa immune response.

Gut mucosa immune response against harmful intestinal organisms have a strong impact in reduced risk of digestive disorder, through regulating the function of lymphoid tissue located at the mucosa.

According to the article of mucosal immunology, "the mucosal immune system provides protection against pathogens but maintains a tolerance towards non-harmful commensal microbes and benign environmental substances".

4. The immunomodutating effect also found in increased number of IgA+ cells in the the small intestine lamina propria accompanied by an increase in the number of IL-4+, IL-10+ and IFN-γ+ cells.

In this case, the immunomodating effect through expression of production of  IgA+ cells in
protected the intestine lamina propria(based membrance) from pathogens, toxins and food antigens the basement remembrance of the intestine by increased the numbers of interleukin IL-4+, IL-10+ in inhibited production of pro inflammatory cytokins as well as increased function of IFN-γ+  cells in stimulated innate and adaptive immunity against viral, some bacterial and protozoal infections.

Further differentiation also suggested that the enhanced IL-6 secretion of small intestine epithelial cells (IEC) by the Pea protein hydrolysate in stimulation IgA-secretion, probably associated to numbers of mechanism, particularly in TLR2 and TLR4 function in pathogen recognition and activation of innate immunity.

Taking altogether, green peas or common peas may be considered as therapeutic treatment in enhanced mmunomodulating activity, particularly to aging adults and people with history of weakened immunity.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Immunomodulating activity of exopolysaccharide-producing Leuconostoc mesenteroides strain NTM048 from green peas by Matsuzaki C1, Kamishima K, Matsumoto K, Koga H, Katayama T, Yamamoto K, Hisa K.(PubMed)
(2)Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds by Ndiaye F1, Vuong T, Duarte J, Aluko RE, Matar C.(PubMed)
(3) Mucosal immunology by Nature.com

Food Therapy: Dried Peas, The Best in Prediction, Prevention and Treatment of Liver Diseases

Kyle J. Norton


Intake of dried peas daily and regularly may associate to reduce risk of liver diseases, scientists at some respectable institute studies suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Liver diseases are set of medical condition, ranging from Cirrhosis, or scarring of the liver. Inflammation (hepatitis) from infectious (hepatitis B, hepatitis C) to benign and malignant tumors.

In a hydroalcoholic extract (PE) of pea (Pisum sativum L.) by-product was investigate for its hepatoprotective against CCl4-induced oxidative stress and hepatic damage in rats, researchers at the Cairo University after taking account of existed con founders, found that
1. The by product displayed a significant effect in reduced ROS expression in induction of liver damamge through enhance antioxidant activity.
2. N-butanol fraction isolated from hydroalcoholic extract (PE) demonstrated stronger liver protective effect in compare to other petrochemicals.

The findings demonstrated that  hydroalcoholic extract (PE) of pea by-product can be utilized to obtain high value added products for therapeutic use in ameliorated risk and treatment liver diseases.

People who have a history of liver problems may consider to add portions of dried peas into their diet for preventive measure.

Further analysis the study also indicated that the by product also exert a significant antioxidant activity against the free radical expression and intimated a chain of harmful domino effect in inducing oxidative stress in the liver, which has been considered as a conjoint pathological mechanism.

Dr. Li S, the lead author at the University of Hong Kong, said, "(there is no surprise that) various factors that cause oxidative stress in liver and effects of antioxidants in the prevention and treatment of liver diseases ......".

In deed, application of antioxidants in animal studies has revealed a significant effect in prevented and cured liver diseases involving oxidative stress.

In the concerns of types of phytochemicals may have contributed to the hepatoprotective effect from peas, researchers at the Kyoto Pharmaceutical University launched an investigation to isolate some suspected chemical compounds from the young seedpods of garden peas, showed that

1. Not all chemicals isolated exerted similar in liver protection

2. Some compounds are more effective in compared to others

Further differentiation, researchers suggested, out of many components, Quercetin 3-sophorotrioside, was found to show clinical significantly protective effects on liver injury induced by D-galactosamine and lipopolysaccharide and by carbon tetrachloride in mice study, in compared those of ionone glucoside, pisumionoside, a phenethyl glycoside, sayaendoside, and two acylated flavonol oligoglycosides, pisumflavonosides.

More importantly, in support of the above analysis, researchers at the Changhai Hospital also conducted a study to evaluate the alpha-fetoprotein reactive to Pisum sativum agglutinin levels (AFP-R-PSA) of 24 patients with hepatocellular carcinoma (HCC) and 54 patients with benign liver diseases (BLD) showed that

1. Alpha-fetoprotein levels were higher in patient with liver cancer and suggested that the measured AFP-R-PSA level above 25% may be considered as a value in highly suggestive of HCC with a positive prediction value of 98% accuracy.
2. According to the sensitivity of the test, value of 74% in serum AFP level below 400 micrograms/L was found in 31 patients with a tumor size less than 5cm.
3. In the combined test of (AFP-R-PSA), the detection rate of small HCC was increased from 32% to 87%.

It is amazing that Pisum sativum lectin or agglutinin (PSA), another chemical compound isolated from peas also have a strong effect in prediction of the development and size benign liver diseases (BLD) and liver cancers.

With all information collected from the data of medical literature, we believed,  the efficacy of dried peas in reduced risk and treatment of liver diseases may be attributed to various unknown mechanisms, that are waiting to discover.

These effectiveness also does not assure that patients with liver disease can be cured by adding a significant portions of pea into their diet, because of the small sample sizes and only ingredients isolated from peas were used to perform these testing in all studies. 

But taking together, it is safe to conclude that intake of dried peas may have a profound and positive potency in induced hetapoprotective against liver diseases.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Bioassay-guided fractionation of a hepatoprotective and antioxidant extract of peaby-product by Seida AA1, El Tanbouly ND, Islam WT, Eid HH, El Maraghy SA, El Senousy AS.(PubMed)
(2) Medicinal foodstuffs. XXV. Hepatoprotective principle and structures of ionone glucoside, phenethyl glycoside, and flavonol oligoglycosides from young seedpods of garden peas, Pisum sativum L by Murakami T1, Kohno K, Ninomiya K, Matsuda H, Yoshikawa M.(PubMed)
(3) Alpha-fetoprotein reaction to Pisum sativum agglutinin in differentiation of benign liver diseases from hepatocellular carcinoma by Yin ZF1, Tu ZX, Cui ZF, Wu MC.(PubMed)
(4) The Role of Oxidative Stress and Antioxidants in Liver Diseases by Li S1, Tan HY2, Wang N3, Zhang ZJ4, Lao L5, Wong CW6, Feng Y7.(PubMed)

Food Therapy: Coffee, A linear Association to Reduced Risk and Progression of Parkinson's Disease

By Kyle J. Norton


Intake of coffee caffeine regularly are associated to a significantly attenuated risk of neurodegenerative conditions, particular in the onset of Parkinson's diseases, a recent study suggested.

Parkinson's disease is neuro degenerative disease caused by deficiency of the dopamine and.degeneration of the basal ganglia of the brain, affecting muscular normal function.

Dopamine acted as as a neurotransmitter and a precursor of other substances including epinephrine.
is a compound present in the body involved brain function in the roles of reward-motivated behavior.

The basal ganglia (or basal nuclei) having a strong interconnected with the cerebral cortex, thalamus, and brainstem, as well as several other brain areas, is a group of subcortical neurons, of varied origin, in the brains of vertebrates with function involved primarily processing movement related information such as emotions, motivations, and cognitive functions.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the Harvard School of Public Health, Boston, in compared population comprised 47,351 men and 88,565 women free of Parkinson's disease, stroke, or cancer at baseline, caffeine intake is associated to reduced risk and progression of PD, in compared the top and bottom one-fifth men participants. No effect is found for decaffeinate coffee intake regardless to numbers of cup consumed.

Caffeine, a chemical stimulant found abundantly in caffeinated products, including tea and coffee is a class of methylxanthine having a profound impact in central nervous system (CNS).

Interestingly, among women, numbers of caffeinated coffee intake daily have a strong implication in attenuated risk of PD linearly, in compared to lowest intake of moderated intake groups.

Further more, a case-control study conducted in western Washington State in 1992-2000. Incident PD cases (n = 210) and controls (n = 347) with frequency matched on gender and age identified from enrollees of the Group Health Cooperative health maintenance organization, returned questionnaires by participants indicated, consumption of 2 cups/day showed a strong expression in reduced risk of PD.

More importantly, in the review of twenty-six studies included: 7 cohort, 2 nested case-control, 16 case-control, and 1 cross-sectional study, the total relative odd ratio for the association between caffeine intake in low to moderate groups and PD was 0.75.

But, in cohort studies, reduced risk of PD significantly decreased if only women participants were considered.

Researchers, at above study revealed that PD risk is associated to a linear relation between levels of caffeine exposure of relative odd ratio of 0.76, per 300 mg caffeine intake.

Finally, some researchers addressed that, in the concerns of PD patients in expression a significant impairment of dopaminergic neuron transmission, caffeine acted as acts as a nonselective adenosine receptor antagonist may have a profound effect in treatment of PD through adenosine A2A receptors function in regulation of glutamate and dopamine release. 

Taking together, there is no doubt that risk of PD has an extremely inverse association to caffeine intake, particular in moderated drinkers.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Can coffee consumption lower the risk of Alzheimer's disease and Parkinson's disease? A literature review by Wierzejska R1.(PubMed)
92) Prospective study of caffeine consumption and risk of Parkinson's disease in men and women by Ascherio A1, Zhang SM, Hernán MA, Kawachi I, Colditz GA, Speizer FE, Willett WC.(PubMed)
(3) Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake by Checkoway H1, Powers K, Smith-Weller T, Franklin GM, Longstreth WT Jr, Swanson PD.(PubMed)
(4) Association of coffee and caffeine intake with the risk of Parkinson disease by Ross GW1, Abbott RD, Petrovitch H, Morens DM, Grandinetti A, Tung KH, Tanner CM, Masaki KH, Blanchette PL, Curb JD, Popper JS, White LR.(PubMed)

Food Therapy: Beet or Beetroot, A Functional Food in Reduced Risk and Treatment of Inflammatory Bowel Disease

Kyle J. Norton


Beet or Beetroot, may have a potential effect in ameliorated abnormal function of white blood cells such as neutrophils in reduced risk and treatment of inflammatory bowel disease.

Inflammation is a natural process of immune defense to remove injurious agents, cells and tissues from the body.

Inflammatory bowel disease is the boarder term of conditions characterized by chronic inflammation of intestines, including ulcerative colitis and Crohn disease.

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to the Poznan University of Medial Science, beetroot (Beta vulgaris var. rubra) products and their major component betanin exhibited antioxidant activities against abnormal neutrophils in modulated reactive oxygen species (ROS) production and DNA damage, in healthy subjects.

The efficacy of betanin in reduced reactive oxygen species (ROS) expression is the result of  exerting antioxidant free radical scavenging and neutralizing activities by slowed down or prevented initiation of free radical chain reaction.

Additionally, betanin, as a major phytochemical also ameliorated the elevated ROS expression in promoted oxidative stress which was found to have a strong implication to cause cellular DNA damage. Some researchers suggested that betanin reduced risk of cellular DNA damage.probably through inter influenced the pro apoptotic caspase-3 in the action of release of ROS and apoptotic cell death.

In deed, activities of betanin in attenuated risk of over expression of ROS in induction of DNA also may be an extrinsic way of the phytochemical in exerting anti-inflammatory and potentially cancer preventive activity.

Further analysis and taking into account of other con founders, researchers once again indicated that betanin with concentration of 100 μM for 24 h, inhibited pro inflammatory expression in ulcerative colitis (UC) and Crohn's disease (CD) patients by protecting the digestive tract that can be observed through action in decreased oxidative DNA damage and promoted apoptosis in neutrophils.

In fact, betaine and other phytochemical baicalein have shown to provide various health benefits to organism in many ways, including down-regulation of inflammation against colitis-associated colon tumorigenesis in tested animal.

In case of anti inflammation, both betaine and baicalein also found to demonstrate a magnificent impact in regulation of the pro inflammatory cytokins such as IL-1β, PGE2, and TNF-α in NF-ĸB activation beside activities in inhibited expression of ROS.

Interestingly, in patients with ulcerative colitis, arabino-oligosaccharides (AOS) derived from sugar beet pulp, stimulated Bifidobacterium spp. and Lactobacillus spp. accompanied by a high production of acetate in eliciting anti-inflammatory responses, thus attenuating inflammatory conditions in UC patients.

The observation illustrated that beet may have a potential in acting as prebiotic to enhance the growth of beneficial microorganisms in the intestines, thus reducing.risk of flare-ups in UC patients.

Furthermore, arabino-oligosaccharides (AOS) also showed to elevate the failure of local anaesthesia in inflamed tissues through lowering of intestinal pH

The findings of improved antioxidant in attenuated free radical in induction of DNA and promotion of abnormal expression of neutrophils, as well as acting as prebiotic suggested that beet may be considered as functional food in reduced risk of chronically digestive inflammatory diseases, particularly in inflammatory bowel disease.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) DNA damage and apoptosis in blood neutrophils of inflammatory bowel diseasepatients and in Caco-2 cells in vitro exposed to betanin by Zielińska-Przyjemska M1, Olejnik A2, Dobrowolska-Zachwieja A3, Łuczak M4, Baer-Dubowska W1.(PubMed)
(2) Modulation of Colitis-associated Colon Tumorigenesis by Baicalein and Betaine by Kim DH1, Sung B1, Chung HY1, Kim ND1.(PubMed)
(3) In vitro fermentation of sugar beet arabino-oligosaccharides by fecal microbiota obtained from patients with ulcerative colitis to selectively stimulate the growth of Bifidobacterium spp. and Lactobacillus spp by Vigsnæs LK1, Holck J, Meyer AS, Licht TR.(PubMed)
(4) Anti-inflammatory activity of baicalein in LPS-stimulated RAW264.7 macrophages via estrogen receptor and NF-κB-dependent pathways by Fan GW1, Zhang Y, Jiang X, Zhu Y, Wang B, Su L, Cao W, Zhang H, Gao X.(PubMed)

Food Therapy: Dried Peas (Legumes) in Reduced Risk and Treatment of Prostate Cancer

Kyle J. Norton


Intake of Legume, particular dried Peas daily and regularly may reduce risk and treatment of prostate cancer, some scientists suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Prostate cancer is medical condition characterized by irregular cell growth in the prostate. Over 11.4 million of men will be diagnosed with prostate cancer at some points during their lifetime, according to statistic.

According to the study at the Yamagata University School of Medicine, in the investigated effect of some flavonoids, isolated from fruits, vegetables, and peas in risk of prostate cancer, using human LNCaP prostate cancer cells researchers found that
1. Genistein, a member of group of flavonoids exerted a significant effect in cell cycle arrest at the G2/M phases, attributed to the suppression of cyclin B expression.

2. The suppression of genistein induced the cyclin-dependent kinase inhibitor p21 which plays an important role in cell cycle progression.

The effect of flavonoids to induce prostate cancer cells apoptosis was attributed to suppression of proteins in control the division of cells by activating gcyclin-dependent kinase (Cdk) enzymes in production p21 antibody.

This result may provide additional persuasion for holistic practitioners to ask their prostate problematic clients to add a portion of rich flavonoids foods into their daily diet.

In concerns of the progressive effect of dietary and lifestyle characteristics and implication of risk of prostate cancer, researchers at the Loma Linda University School of Medicine, conducted a study men of completed a detailed lifestyle questionnaire in 1976 with monitored for cancer incidence until the end of 1982. During the 6-year follow-up period, researchers indicated that  180 histologically confirmed prostate cancers were detected among some 78,000 man-years of follow-up.

Further analysis of the returned questionnaire from the subjects, researchers filed the following interesting results
1. Contrast to general belief, age was inversely associated to risk of prostate cancers
2. History of prostate "trouble" was associated with a 60% increase in risk of the cancer development
3. Increased intake of animal product consumption was also associated to increased risk of the cancer

More intrusively, researchers also emphasized that increasing consumption of beans, lentils and peas, ...........were all associated with significantly decreased prostate cancer risk.

The result of findings although suggested that legume may have a positive effect in reduced prostate cancer incidence, it doesn't mean that you can just eat a large portion of such foods everyday and expected the problem will go away. Negative dietary and life style habits sometimes have a strong implication of the outcome.

More importantly, in the study to confirm the effective of common constituents of seeds (rice, beans, and maize) in ameliorated risk of breast, colon, and skin cancers in animals, researchers suggested that antioxidant rich in seeds may play an important role in reduced oxidative stress and ionizing radiation in initiated cancer and cancer progression.

Dr. Thapa D. in response to the effect of antioxidant and risk of prostate cancer, said, "It has also been established that inflammation is a precursor in neoplastic transformation of the prostate". and "Although, a vast body of experimental and clinical evidence shows efficacy of antioxidants as preventive strategies for prostate cancer, there is a lack of consistent agreement in outcomes especially from recent large-scale randomized clinical trials".

The suggestion indicated that other components which have not been discovered may have a significant effect in reduced risk of prostate cancer beside legume antioxidant activities.

Most study of legume in attenuated risk of treatment of prostate cancer are in the experiment state with small sample size and contradiction are expected due to many factors including studied designed, sample chosen, race,  eating habits,......., therefore a large sample and cohost study, taking into account of other con founders are necessary to confirm this validation.

However, with the information findings, it is safe to suggested that adding some portions of legume, such as peas, into your diet may have an profound effect in reduced risk of prostate cancer.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effect of flavonoids on cell cycle progression in prostate cancer cells by Kobayashi T1, Nakata T, Kuzumaki T.(PubMed)
(2) Cohort study of diet, lifestyle, and prostate cancer in Adventist men by Mills PK1, Beeson WL, Phillips RL, Fraser GE.(PubMed)
(3) Protease inhibitors: possible anticarcinogens in edible seeds by Troll W, Wiesner R.(PubMed)
(4) Antioxidants for prostate cancer chemoprevention: challenges and opportunities by Thapa D1, Ghosh R.(PubMed)

Alternative Therapy: Yoga and Your Heart

Kyle J. Norton

Yoga may have a profound effect in improved heart rate regardless to patients precondition,some institution studies suggested

Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the study to examine the effects of an 8-week yoga program on heart rate variability and mood in generally healthy women (n=52) randomly assigned to a yoga(vcomprised a 60-minute session twice a week. Each session consisted of breathing exercises, yoga pose practice, and supine meditation/relaxation) group or a control group, in compared to control, yoga group expressed insignificant change in heart rate.

But after taking into account of other con founders, researchers insisted that long term yoga lessons may have a positive effect in heart rate in women with higher levels of stress and trait anxiety.

Other researchers in the concern of the effect of yoga in reduced high blood pressure but not heart rate launched an investigation of 26 male volunteers assigned either in yoga with assessment taken at 3 time points: Pre (5 minutes), during (15 minutes; for ANYB or BAW) and Post (5 minutes)
1. Yoga group expressed a significant decrease (repeated measures ANOVA) in systolic BP and respiration rate
2. Breath rate was found to be difference in all 3 intervals, measured by awareness (BAW) assay.

Further assessment, Dr. Telles S, the led author suggested that the vagal activity involved in heart rate regulation increased during and after ANYB, may contribute to the decrease in BP and changes in the HRV.

More importantly, in a randomized clinical trials (RCTs) in compared yoga against any type of control intervention in healthy individuals or patients with any medical condition, through searching the literature published online database wit 14 studies satisfied the criteria selected, researchers found that
1. Yoga intervention expressed in Ten RCTs showed favourable effects of yoga on various domains of HRV,
2. The meta-analysis (MA) of two trials did not show the favourable effects of yoga compared to usual care.

After taking into account of other influences, researchers suggested that there was no convincing evidence for the effectiveness of yoga in modulating HRV in patients or healthy subjects. 

The information finding, although showed a contradictory results of yoga in improved heart rate, some researchers insisted that long term intervention may prove the differences

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of Yoga on Heart Rate Variability and Mood in Women: A Randomized Controlled Trial by Chu IH1, Lin YJ1, Wu WL1, Chang YK2, Lin IM3.(PubMed)
(2) Blood pressure and heart rate variability during yoga-based alternate nostril breathing practice and breath awareness by Telles S1, Sharma SK1, Balkrishna A1.(PubMed)
(3) Yoga for Heart Rate Variability: A Systematic Review and Meta-analysis of Randomized Clinical Trials.by Posadzki P1, Kuzdzal A, Lee MS, Ernst E.(PubMed)

Food Therapy: Vegetables and Fruits Intake > 9 Servings Daily In Reduced Risk of Pancreatic cancer

Kyle J. Norton


Intake of Vegetables and Fruits daily and regularly may reduce risk of pancreatic cancer, some renowned institute studies suggested.


Pancreas cancer is a medical condition characterized by uncontrollable cells growth in the pancreas.
at the late stage, the cancer cells may travel to infect other organs and tissues distanced away from the original site. And it is considered as one of most devastating and rapidly fatal cancer.

According to the statistic, the risk of pancreatic cancer, in population is 1.4% with 44000 new cases

diagnosed every year in US alone.

In the investigate the data  of 532 cases of pancreatic cancer, in patients examined between 1995 and 1999 and to clarify the substantial risk of pancreatic cancer, in this group of subjects, the University of California San Franciscoconducted a population-based case-control study to determine the association between vegetables and fruits and pancreatic cancer, with matching 1,701 age- and sex controls. After considering other con founders, researchers filed the following results

1. Intake of more than 9 serving of vegetables and fruit daily showed a substantially reduced risk of pancreatic cancer,in compared to control group.

2. The relative prevalence of pancreatic cancer, was reduced to .49 

3. Intake of bean score a highest relative odd ration of .46 in compared to intake of other vegetables and fruits intake group.

Further analysis of the returned questionnaire, researchers also indicated that risk of pancreatic cancer, reduced substantially to group with intake of more than 9 severing daily in compared group consuming less than five servings per day of total vegetables and fruits.

In support of the above differentiation, researchers at the Mayo Clinic, also conducted a study to examine the risk of pancreas cancer in fruit, vegetable, fiber, and grain consumption of 384 rapidly ascertained cases and 983 controls (frequency matched on age (±5 years), race, sex, and residence), after analyzing the returned completed epidemiological surveys and 144-item food frequency questionnaires, researchers, after adjusting for diabetes or total sugar intake, indicated that in compare to highest to lowest quintiles, intake of citrus, melon, and berries, other fruits, dark green vegetables, deep yellow vegetables, tomato, other vegetables, dry bean and pea, insoluble fiber, soluble fiber daily had a strong effect in reduced risk of pancreatic cancer,.

Additionally the study also emphasized that increased intake of non-whole grains product is associated to positive risk of pancreatic cancer development. In other word, lower intake of fruits, vegetables, whole grains, and fiber is associated to pancreatic cancer risk.

Although the study did not directly address the health benefits of dried peas in reduced risk of pancreatic cancer, it is safe to suggested that as a member of bean group, dried peas may induce the same relative odd ratio in compare to control.

More interestingly, in a prospective study of fatal pancreas cancer among 34,000 California Seventh-day Adventists between 1976 and 1983(40 deaths from pancreatic cancer, occurred during the follow-up period) to evaluate whether raw fruits and vegetables consumption has been consistently associated with decreased risk of pancreatic cancer,. after analysis the dietary habits and medical history of all the patients record, researchers insisted that
1. Increasing consumption of vegetarian protein products, beans, lentils, and peas as well as dried fruit was associated with highly significant protective relationships to pancreatic cancer, risk.
2. Premedical condition also increase risk of pancreas cancer
3. Patients with history of surgery for peptic or duodenal ulcer were also at risk of pancreatic cancer development.

The findings suggested that regardless to medical condition and prehistory of surgery, intake of vegetables and fruits daily have a profound effect in reduced risk of cancer incidence in compare to non consuming group.

Dr. Mills PK, the lead author said, "the protective relationships associated with frequent consumption of vegetables and fruits high in protease-inhibitor content are more important than any increase in pancreas cancer risk attendant on frequent consumption of meat or other animal products".

Taking altogether, increasing intake of vegetables and fruits and reducing intake of meat and animal product  daily are necessary to ensure the less prevalence of risk of pancreatic cancer.

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Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Vegetable and fruit intake and pancreatic cancer in a population-based case-control study in the San Francisco bay area by Chan JM1, Wang F, Holly EA.(PubMed)
(2) Fruit and vegetable consumption is inversely associated with having pancreaticcancer by Jansen RJ1, Robinson DP, Stolzenberg-Solomon RZ, Bamlet WR, de Andrade M, Oberg AL, Hammer TJ, Rabe KG, Anderson KE, Olson JE, Sinha R, Petersen GM.(PubMed)
(3) Dietary habits and past medical history as related to fatal pancreas cancer risk among Adventists by Mills PK1, Beeson WL, Abbey DE, Fraser GE, Phillips RL.(PubMed)