Food Therapy: Beet or Beetroot, A Functional Food in Reduced Risk and Treatment of Inflammatory Bowel Disease

Kyle J. Norton


Beet or Beetroot, may have a potential effect in ameliorated abnormal function of white blood cells such as neutrophils in reduced risk and treatment of inflammatory bowel disease.

Inflammation is a natural process of immune defense to remove injurious agents, cells and tissues from the body.

Inflammatory bowel disease is the boarder term of conditions characterized by chronic inflammation of intestines, including ulcerative colitis and Crohn disease.

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to the Poznan University of Medial Science, beetroot (Beta vulgaris var. rubra) products and their major component betanin exhibited antioxidant activities against abnormal neutrophils in modulated reactive oxygen species (ROS) production and DNA damage, in healthy subjects.

The efficacy of betanin in reduced reactive oxygen species (ROS) expression is the result of  exerting antioxidant free radical scavenging and neutralizing activities by slowed down or prevented initiation of free radical chain reaction.

Additionally, betanin, as a major phytochemical also ameliorated the elevated ROS expression in promoted oxidative stress which was found to have a strong implication to cause cellular DNA damage. Some researchers suggested that betanin reduced risk of cellular DNA damage.probably through inter influenced the pro apoptotic caspase-3 in the action of release of ROS and apoptotic cell death.

In deed, activities of betanin in attenuated risk of over expression of ROS in induction of DNA also may be an extrinsic way of the phytochemical in exerting anti-inflammatory and potentially cancer preventive activity.

Further analysis and taking into account of other con founders, researchers once again indicated that betanin with concentration of 100 μM for 24 h, inhibited pro inflammatory expression in ulcerative colitis (UC) and Crohn's disease (CD) patients by protecting the digestive tract that can be observed through action in decreased oxidative DNA damage and promoted apoptosis in neutrophils.

In fact, betaine and other phytochemical baicalein have shown to provide various health benefits to organism in many ways, including down-regulation of inflammation against colitis-associated colon tumorigenesis in tested animal.

In case of anti inflammation, both betaine and baicalein also found to demonstrate a magnificent impact in regulation of the pro inflammatory cytokins such as IL-1β, PGE2, and TNF-α in NF-ĸB activation beside activities in inhibited expression of ROS.

Interestingly, in patients with ulcerative colitis, arabino-oligosaccharides (AOS) derived from sugar beet pulp, stimulated Bifidobacterium spp. and Lactobacillus spp. accompanied by a high production of acetate in eliciting anti-inflammatory responses, thus attenuating inflammatory conditions in UC patients.

The observation illustrated that beet may have a potential in acting as prebiotic to enhance the growth of beneficial microorganisms in the intestines, thus reducing.risk of flare-ups in UC patients.

Furthermore, arabino-oligosaccharides (AOS) also showed to elevate the failure of local anaesthesia in inflamed tissues through lowering of intestinal pH

The findings of improved antioxidant in attenuated free radical in induction of DNA and promotion of abnormal expression of neutrophils, as well as acting as prebiotic suggested that beet may be considered as functional food in reduced risk of chronically digestive inflammatory diseases, particularly in inflammatory bowel disease.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) DNA damage and apoptosis in blood neutrophils of inflammatory bowel diseasepatients and in Caco-2 cells in vitro exposed to betanin by Zielińska-Przyjemska M1, Olejnik A2, Dobrowolska-Zachwieja A3, Łuczak M4, Baer-Dubowska W1.(PubMed)
(2) Modulation of Colitis-associated Colon Tumorigenesis by Baicalein and Betaine by Kim DH1, Sung B1, Chung HY1, Kim ND1.(PubMed)
(3) In vitro fermentation of sugar beet arabino-oligosaccharides by fecal microbiota obtained from patients with ulcerative colitis to selectively stimulate the growth of Bifidobacterium spp. and Lactobacillus spp by Vigsnæs LK1, Holck J, Meyer AS, Licht TR.(PubMed)
(4) Anti-inflammatory activity of baicalein in LPS-stimulated RAW264.7 macrophages via estrogen receptor and NF-κB-dependent pathways by Fan GW1, Zhang Y, Jiang X, Zhu Y, Wang B, Su L, Cao W, Zhang H, Gao X.(PubMed)

Food Therapy: Dried Peas (Legumes) in Reduced Risk and Treatment of Prostate Cancer

Kyle J. Norton


Intake of Legume, particular dried Peas daily and regularly may reduce risk and treatment of prostate cancer, some scientists suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Prostate cancer is medical condition characterized by irregular cell growth in the prostate. Over 11.4 million of men will be diagnosed with prostate cancer at some points during their lifetime, according to statistic.

According to the study at the Yamagata University School of Medicine, in the investigated effect of some flavonoids, isolated from fruits, vegetables, and peas in risk of prostate cancer, using human LNCaP prostate cancer cells researchers found that
1. Genistein, a member of group of flavonoids exerted a significant effect in cell cycle arrest at the G2/M phases, attributed to the suppression of cyclin B expression.

2. The suppression of genistein induced the cyclin-dependent kinase inhibitor p21 which plays an important role in cell cycle progression.

The effect of flavonoids to induce prostate cancer cells apoptosis was attributed to suppression of proteins in control the division of cells by activating gcyclin-dependent kinase (Cdk) enzymes in production p21 antibody.

This result may provide additional persuasion for holistic practitioners to ask their prostate problematic clients to add a portion of rich flavonoids foods into their daily diet.

In concerns of the progressive effect of dietary and lifestyle characteristics and implication of risk of prostate cancer, researchers at the Loma Linda University School of Medicine, conducted a study men of completed a detailed lifestyle questionnaire in 1976 with monitored for cancer incidence until the end of 1982. During the 6-year follow-up period, researchers indicated that  180 histologically confirmed prostate cancers were detected among some 78,000 man-years of follow-up.

Further analysis of the returned questionnaire from the subjects, researchers filed the following interesting results
1. Contrast to general belief, age was inversely associated to risk of prostate cancers
2. History of prostate "trouble" was associated with a 60% increase in risk of the cancer development
3. Increased intake of animal product consumption was also associated to increased risk of the cancer

More intrusively, researchers also emphasized that increasing consumption of beans, lentils and peas, ...........were all associated with significantly decreased prostate cancer risk.

The result of findings although suggested that legume may have a positive effect in reduced prostate cancer incidence, it doesn't mean that you can just eat a large portion of such foods everyday and expected the problem will go away. Negative dietary and life style habits sometimes have a strong implication of the outcome.

More importantly, in the study to confirm the effective of common constituents of seeds (rice, beans, and maize) in ameliorated risk of breast, colon, and skin cancers in animals, researchers suggested that antioxidant rich in seeds may play an important role in reduced oxidative stress and ionizing radiation in initiated cancer and cancer progression.

Dr. Thapa D. in response to the effect of antioxidant and risk of prostate cancer, said, "It has also been established that inflammation is a precursor in neoplastic transformation of the prostate". and "Although, a vast body of experimental and clinical evidence shows efficacy of antioxidants as preventive strategies for prostate cancer, there is a lack of consistent agreement in outcomes especially from recent large-scale randomized clinical trials".

The suggestion indicated that other components which have not been discovered may have a significant effect in reduced risk of prostate cancer beside legume antioxidant activities.

Most study of legume in attenuated risk of treatment of prostate cancer are in the experiment state with small sample size and contradiction are expected due to many factors including studied designed, sample chosen, race,  eating habits,......., therefore a large sample and cohost study, taking into account of other con founders are necessary to confirm this validation.

However, with the information findings, it is safe to suggested that adding some portions of legume, such as peas, into your diet may have an profound effect in reduced risk of prostate cancer.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effect of flavonoids on cell cycle progression in prostate cancer cells by Kobayashi T1, Nakata T, Kuzumaki T.(PubMed)
(2) Cohort study of diet, lifestyle, and prostate cancer in Adventist men by Mills PK1, Beeson WL, Phillips RL, Fraser GE.(PubMed)
(3) Protease inhibitors: possible anticarcinogens in edible seeds by Troll W, Wiesner R.(PubMed)
(4) Antioxidants for prostate cancer chemoprevention: challenges and opportunities by Thapa D1, Ghosh R.(PubMed)

Alternative Therapy: Yoga and Your Heart

Kyle J. Norton

Yoga may have a profound effect in improved heart rate regardless to patients precondition,some institution studies suggested

Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the study to examine the effects of an 8-week yoga program on heart rate variability and mood in generally healthy women (n=52) randomly assigned to a yoga(vcomprised a 60-minute session twice a week. Each session consisted of breathing exercises, yoga pose practice, and supine meditation/relaxation) group or a control group, in compared to control, yoga group expressed insignificant change in heart rate.

But after taking into account of other con founders, researchers insisted that long term yoga lessons may have a positive effect in heart rate in women with higher levels of stress and trait anxiety.

Other researchers in the concern of the effect of yoga in reduced high blood pressure but not heart rate launched an investigation of 26 male volunteers assigned either in yoga with assessment taken at 3 time points: Pre (5 minutes), during (15 minutes; for ANYB or BAW) and Post (5 minutes)
1. Yoga group expressed a significant decrease (repeated measures ANOVA) in systolic BP and respiration rate
2. Breath rate was found to be difference in all 3 intervals, measured by awareness (BAW) assay.

Further assessment, Dr. Telles S, the led author suggested that the vagal activity involved in heart rate regulation increased during and after ANYB, may contribute to the decrease in BP and changes in the HRV.

More importantly, in a randomized clinical trials (RCTs) in compared yoga against any type of control intervention in healthy individuals or patients with any medical condition, through searching the literature published online database wit 14 studies satisfied the criteria selected, researchers found that
1. Yoga intervention expressed in Ten RCTs showed favourable effects of yoga on various domains of HRV,
2. The meta-analysis (MA) of two trials did not show the favourable effects of yoga compared to usual care.

After taking into account of other influences, researchers suggested that there was no convincing evidence for the effectiveness of yoga in modulating HRV in patients or healthy subjects. 

The information finding, although showed a contradictory results of yoga in improved heart rate, some researchers insisted that long term intervention may prove the differences

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of Yoga on Heart Rate Variability and Mood in Women: A Randomized Controlled Trial by Chu IH1, Lin YJ1, Wu WL1, Chang YK2, Lin IM3.(PubMed)
(2) Blood pressure and heart rate variability during yoga-based alternate nostril breathing practice and breath awareness by Telles S1, Sharma SK1, Balkrishna A1.(PubMed)
(3) Yoga for Heart Rate Variability: A Systematic Review and Meta-analysis of Randomized Clinical Trials.by Posadzki P1, Kuzdzal A, Lee MS, Ernst E.(PubMed)

Food Therapy: Vegetables and Fruits Intake > 9 Servings Daily In Reduced Risk of Pancreatic cancer

Kyle J. Norton


Intake of Vegetables and Fruits daily and regularly may reduce risk of pancreatic cancer, some renowned institute studies suggested.


Pancreas cancer is a medical condition characterized by uncontrollable cells growth in the pancreas.
at the late stage, the cancer cells may travel to infect other organs and tissues distanced away from the original site. And it is considered as one of most devastating and rapidly fatal cancer.

According to the statistic, the risk of pancreatic cancer, in population is 1.4% with 44000 new cases

diagnosed every year in US alone.

In the investigate the data  of 532 cases of pancreatic cancer, in patients examined between 1995 and 1999 and to clarify the substantial risk of pancreatic cancer, in this group of subjects, the University of California San Franciscoconducted a population-based case-control study to determine the association between vegetables and fruits and pancreatic cancer, with matching 1,701 age- and sex controls. After considering other con founders, researchers filed the following results

1. Intake of more than 9 serving of vegetables and fruit daily showed a substantially reduced risk of pancreatic cancer,in compared to control group.

2. The relative prevalence of pancreatic cancer, was reduced to .49 

3. Intake of bean score a highest relative odd ration of .46 in compared to intake of other vegetables and fruits intake group.

Further analysis of the returned questionnaire, researchers also indicated that risk of pancreatic cancer, reduced substantially to group with intake of more than 9 severing daily in compared group consuming less than five servings per day of total vegetables and fruits.

In support of the above differentiation, researchers at the Mayo Clinic, also conducted a study to examine the risk of pancreas cancer in fruit, vegetable, fiber, and grain consumption of 384 rapidly ascertained cases and 983 controls (frequency matched on age (±5 years), race, sex, and residence), after analyzing the returned completed epidemiological surveys and 144-item food frequency questionnaires, researchers, after adjusting for diabetes or total sugar intake, indicated that in compare to highest to lowest quintiles, intake of citrus, melon, and berries, other fruits, dark green vegetables, deep yellow vegetables, tomato, other vegetables, dry bean and pea, insoluble fiber, soluble fiber daily had a strong effect in reduced risk of pancreatic cancer,.

Additionally the study also emphasized that increased intake of non-whole grains product is associated to positive risk of pancreatic cancer development. In other word, lower intake of fruits, vegetables, whole grains, and fiber is associated to pancreatic cancer risk.

Although the study did not directly address the health benefits of dried peas in reduced risk of pancreatic cancer, it is safe to suggested that as a member of bean group, dried peas may induce the same relative odd ratio in compare to control.

More interestingly, in a prospective study of fatal pancreas cancer among 34,000 California Seventh-day Adventists between 1976 and 1983(40 deaths from pancreatic cancer, occurred during the follow-up period) to evaluate whether raw fruits and vegetables consumption has been consistently associated with decreased risk of pancreatic cancer,. after analysis the dietary habits and medical history of all the patients record, researchers insisted that
1. Increasing consumption of vegetarian protein products, beans, lentils, and peas as well as dried fruit was associated with highly significant protective relationships to pancreatic cancer, risk.
2. Premedical condition also increase risk of pancreas cancer
3. Patients with history of surgery for peptic or duodenal ulcer were also at risk of pancreatic cancer development.

The findings suggested that regardless to medical condition and prehistory of surgery, intake of vegetables and fruits daily have a profound effect in reduced risk of cancer incidence in compare to non consuming group.

Dr. Mills PK, the lead author said, "the protective relationships associated with frequent consumption of vegetables and fruits high in protease-inhibitor content are more important than any increase in pancreas cancer risk attendant on frequent consumption of meat or other animal products".

Taking altogether, increasing intake of vegetables and fruits and reducing intake of meat and animal product  daily are necessary to ensure the less prevalence of risk of pancreatic cancer.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Vegetable and fruit intake and pancreatic cancer in a population-based case-control study in the San Francisco bay area by Chan JM1, Wang F, Holly EA.(PubMed)
(2) Fruit and vegetable consumption is inversely associated with having pancreaticcancer by Jansen RJ1, Robinson DP, Stolzenberg-Solomon RZ, Bamlet WR, de Andrade M, Oberg AL, Hammer TJ, Rabe KG, Anderson KE, Olson JE, Sinha R, Petersen GM.(PubMed)
(3) Dietary habits and past medical history as related to fatal pancreas cancer risk among Adventists by Mills PK1, Beeson WL, Abbey DE, Fraser GE, Phillips RL.(PubMed)

Herbal Therapy: Green tea, in Reduced Risk and Treatment of Alzheimer's disease

Kyle J. Norton

Green tea may an integrated form of treatment for patient with Alzheimer's disease through many mechanisms, a recent study proposed.

Green tea, considered as a functional food, linking numbers of health benefit has been reported by several renowned research and studies. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But a slice of ginger in the drink will neutralize the yin over expression in green tea.

Alzheimer's disease is a neuro-degenerative condition of loss or decrease of cognitive and memory functions due to aging.

According to the Maternal and Infant Health, ASL NA 3 SUD, epigallocatechin and gallic acid, (-)-Epigallocatechin-3-Gallate (EGCG), found in green tea exerted a strong anti-inflammatory and anti oxidative properties in protection against neuronal damage and brain edema.

The study also stated that green tea may also contribute to reduced risk and treatment of AD by ameliorated chronic viral infection, one of the cause in responsible for AD's neuropathology.

Dr. Mandel SA. the lead author and expert in green tea study said, "tea drinking may decrease the incidence of dementia, AD, and PD. In particular, its main catechin polyphenol constituent (-)-epigallocatechin-3-gallate (EGCG) has been shown to exert neuroprotective/neurorescue activities in a wide array of cellular and animal models of neurological disorders".

Other researchers suggested that the efficacy of  epigallocatechin and gallic acid, (-)-Epigallocatechin-3-Gallate (EGCG) in reduced risk of AD may be attributed to
1. The antioxidant activity in ameliorate production of ROS in induced risk of oxidative stress which has been found to associate to production of lipid peroxidation, leading to abnormal deposition of amyloid β (Aβ) peptide

2. Free radical over expression in aging people also vulnerable to imbalance of antioxidant and ROS

may have a negatively direct interaction with proteins, nucleic acids, and other molecules and may also alter their structures and functions in inducing risk AD.

Indeed, as a single ingredient isolated from green tea, epigallocatechin and gallic acid, (-)-Epigallocatechin-3-Gallate (EGCG) have been found to cause toxicity in some cases in medical literature. Therefore taking the ingredient in long term and overdoses may have a implication of liver damage.

In a animal study to evaluate the efficacy of Caffeic acid in AD, mice rats randomly divided into three groups: i) control group, ii) AD model group and iii) caffeic acid group, mice fed with the phytochemical expressed a significant in increased learning deficit and cognitive function demonstrated by the Morris water maze task in compared control.

Additionally, fed mice also displayed of attenuated oxidative stress, inflammation, nuclear factor‑κB‑p65 protein expression involved inflammatory cytokins production and suppressed caspase‑3 activity induced cell death and other mechanisms in the rats with AD.

Interestingly, inflammatory process has shown to have an negative role in increased risk of AD, by causing neuroinflammation, including brain cells such as microglia and astrocytes and subsequently in promoted dysfunction and neuronal death. Therefore by suppressing production of inflammatory cytokins, caffeic acid expressed a significant reduction of AD risk.

The efficacy in contribution of cognitive improvement following caffeic acid application may be due to its antioxidant activity and restoration of cholinergic functions, as deficiency of cholinergic function has shown to effect cognition, behavior and activities of daily living

Taking altogether, there is no doubt that green process a neuro protective against the risk and progression of patients with Alzheimer's disease (AD) attributed to some of the major chemical constituents. But intake of single ingredient isolated from green tea should be taken with care.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) The efficacy of Epigallocatechin-3-gallate (green tea) in the treatment of Alzheimer's disease: an overview of pre-clinical studies and translational perspectives in clinical practice by Cascella M#1, Bimonte S#1, Muzio MR2, Schiavone V3, Cuomo A1.(PubMed)
(2) Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases by Mandel SA1, Amit T, Weinreb O, Reznichenko L, Youdim MB.(PubMed)
(3) Effects of caffeic acid on learning deficits in a model of Alzheimer's disease by Wang Y1, Wang Y2, Li J1, Hua L3, Han B1, Zhang Y1, Yang X3, Zeng Z3, Bai H3, Yin H1, Lou J3.(PubMed)
(4) Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats by Deshmukh R1, Kaundal M2, Bansal V2, Samardeep2(PubMed).

Food Therapy: Beet, The Best in Prevention and Treatment of Bladder Cancer

By Kyle J. Norton

Intake of function food beet root regularly not only lowers the early occurrence but also provides a natural treatment of  bladder cancer without inducing adverse effects.

Bladder cancer is a medical condition characterized by irregular cell growth and multiplied disorderly and uncontrollably in bladder tissues.

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to University of Urbino 'Carlo Bo', betaxanthins and betacyanins, isolated from beet root exerted a significant anti cancer effects in testing bladder cancer cell lines, through expression of antioxidant and pro apoptotic activities.

The anti cancer property of beet root also displayed a strong anti angiogenesis by blocking the cancer cell in established new blood vessel signalling.

When used combination with Vitexin-2-O-xyloside, an apigenin flavone glucoside, betaxanthins and betacyanins also exerted a strong antiproliferative activity in bladder cancer cell lines, intrinsically and extrinsically in expression of apoptosis.

The study also indicated that these combination when used conjunction in  the conventional chemotherapy not only enhanced the effectiveness of treatment in bladder cancer but also overcome the adverse effect of  toxicity and multidrug resistance of cancer cells.

Furthermore, in other study conducted by the same university, Betacyanins (BC) purified from beetroot (Beta vulgaris var. rubra L.) tested,alone or in combination with vitexin-2-O-xyloside (XVX) also isolated from the same vegetable enhanced the ability to reduce the proliferation rate in T24 bladder cancer cells, synergistically.by inhibition of protein of gene in promoted cell survival and enhanced cancer apoptosis.

Taking together, a diet enriched with these bioactive molecules of beet root could be used as function food in prevention and treatment of human bladder cancer.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)
(2) Betacyanins enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells by Scarpa ES1, Emanuelli M2, Frati A1, Pozzi V2, Antonini E1, Diamantini G1, Di Ruscio G3, Sartini D3, Armeni T3, Palma F1, Ninfali P1.(PubMed)
(3) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)

Alternative Therapy: Yoga In Regulation of Gene Expression of Related Diseases

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Yoga intervention may have a potential effect in regulated gene expression in some related diseases, researchers at the University of Oslo suggested.

Mutated gene expression included many factors, most common factors are
1. Gene mutation inherited from gene defect parents
2. Gene expression may be altered in the process of regulatory sequences and the transcription factors, cofactors, chromatin regulators and noncoding RNAs
3. Gene mutation is a natural process to protect existence of human beings. Unfortunately, the process in some cases may produce certain subgroups who are vulnerable and susceptible to some diseases.

Biologically, unnatural causes of gene expression due to prolonged exposure to certain harmful agents such as environment toxins, long term used of single or multi ingredients medication,... may also induce genetic change to the negative ways.

Diseases caused by mutated gene expression, include cancer, autoimmunity, neurological disorders, diabetes...

Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to investigate whether the effects on the mind-body system in increased wellness and supported the healing process from diseases, researchers found that yoga intervention not only improved psychological and physiological functioning but also may have regulated effect in gene expression profiling in circulating immune cells, particularly in the molecular level.

Indeed, yoga can improve immunity through a sequence of post in strengthening the body and relaxing the mind. Some believed that by strengthening the body and relaxing the mind, yoga acted as regulators of gene expression in innate and adaptive cell of immune system, through noncoding RNAs, thus reducing risk of inflammatory and auto immune diseases.

In further exploration of the yoga effect in gene expression in the molecular level, researcher at the joint study led by the Coventry University, postulated that mind-body interventions (MBIs) showed a significantly reverse expression of genes involved in inflammatory reactions induced by stress.

Yoga, a mind-body practice of physical poses, controlled breathing, and meditation or relaxation has been best known to reduce implication of stress in increased production of inflammatory cytokins in gene expression, including interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF alpha), thus reducing risk of inflammatory diseases.

And after examined the changes in gene expression that occur after MBIs and to explore how these molecular changes are related to health, through searching the data base of published literature from PubMed throughout September 2016, researcher indicated that over all studies selected indicated an association of gene changes in yoga intervention was a result downregulation of nuclear factor kappa B pathway.

Furthermore, MBI practices may lead to a reduced risk of inflammation-related diseases, through the reduced effects of chronic stress on gene expression.

Most interestingly, in the assessed possible rapid changes in global gene expression profiles in the peripheral blood mononuclear cells (PBMCs) in healthy people practiced either a comprehensive yoga program or a control regimen, researchers found that SK&P program has a more rapid and significantly greater effect on gene expression in PBMCs compared with the control regimen.

Peripheral blood mononuclear cell (PBMC) include lymphocytes (T cells, B cells, NK cells) ,monocytes and granulocytes which play an important role in improved immune system cellular function in fighting against infection and inflammation, enhanced tissue regeneration, restored function due to injure, .....

Truly, the impact of yoga in protection of gene expression of immune system may involve a complexity of simple gene regulatory networks (GRNs), including the gene expression in PBMCs and inflammatory cytokins

Taking altogether, Yoga intervention and related practices may have a profound effect in gene expression alterations through a complex networks of simple gene regulation in the immune system.

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Sources
(1) Regulation of gene expression by yoga, meditation and related practices: a review of recent studies by Saatcioglu F1(PubMed)
(2) Rapid gene expression changes in peripheral blood lymphocytes upon practice of a comprehensive yoga program by Qu S1, Olafsrud SM, Meza-Zepeda LA, Saatcioglu F.(PubMed)
(3) What Is the Molecular Signature of Mind-Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices by Buric I1,2, Farias M1, Jong J1, Mee C3, Brazil IA1,2,4,5.(PubMed)