The holistic Prevention, Management and Treatment of Dementia - Phytochemical Gallic acid

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                 Phytochemicals Against Dementia

Phytochemicals, the non nutritional parts are natural chemical constituents in plants to protect against diseases and to form color as well as other organoleptic properties. Study of Phytochemicals have emerged as a potential source to find a better treatment or cure some diseases with little or side effects or to create a synthetic equivalence for commercial profits.


Gallic acid is a phytochemical in the class of Phenolic acids, found abundantly in tea, mango, strawberries, rhubarb, soy, etc.
1. Cytotoxic and antioxidative activities(367)
Gallic acid showed to exert its antioxidant in inhibition of free radical effects against 2,2-diphenyl-1-picrylhydrazyl(DPPH), a stable free-radical molecules(354), nitric oxide (NO) and superoxide (SO) radicals(353)(355), probably through its chelation of ferrous ions(355). In bacteria, the phytochemical extract containing gallic acid also exhibited a strong anti microbial effect(357)(358) from species of Hypogymnia physodes and Cladonia foliacea(356); In cancers, gallic acid induced tumor cytotoxic effects(357), through antiproliferative induced apoptosis(359), cell cycle arrest(362) and suppression of cancer cell-mediated angiogenesis(360), such as mitochondrial dysfunction(361). Neurologically. gallic acid reduced oxidative stress and mitochondrial dysfunction causes of the pathology of secondary neuronal damage in induction of dementia(363); its anti-aggregating effect also inhibited α-synuclein (α-syn) causes of many neurological disorders including Parkinson's disease (PD), dementia with Lewy bodies(364).

2. Anti inflammatory activity(367)
Gallic acid showed to inhibit inflammation(366) through its scavenging of superoxide anions, inhibition of myeloperoxidase release and activity via mediation of inflammatory process(365).

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The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

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References
(353) Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. by Lee SJ1, Lee IS, Mar W.(353)
(354) 1,1-Diphenyl-2-picrylhydrazyl radical and superoxide anion scavenging activity of Rhizophora mangle (L.) bar by Janet Calero Sánchez, Roberto Faure García, and Ma. Teresa Mitjavila Cors1(PubMed)
(355) In vitro antioxidant capacity and free radical scavenging evaluation of active metabolite constituents of Newbouldia laevis ethanolic leaf extract by Josiah Bitrus Habu and Bartholomew Okechukwu Ibeh(PMC)
(356) The antimicrobial, mechanical, physical and structural properties of chitosan-gallic acid films Xiuxiu Sun Wayne State University Zhe Wang School of Biological and Agricultural Engineering, Jilin University, China Hoda Kadouh Wayne State University Kequan Zhou Wayne State University, kzhou@wayne.edu(Digital Common)
(357) Antibacterial activity and mode of action of ferulic and gallic acids against pathogenic bacteria by Celeste Simões
(358) Berry phenolics: antimicrobial properties and mechanisms of action against severe human pathogens by Nohynek LJ1, Alakomi HL, Kähkönen MP, Heinonen M, Helander IM, Oksman-Caldentey KM, Puupponen-Pimiä RH.(PubMed)
(359) Gallic Acid Induces the Apoptosis of Human Osteosarcoma Cells In Vitro and In Vivo via the Regulation of Mitogen-Activated Protein Kinase Pathways by Cheng-zhen Liang,1 Xin Zhang,1 Hao Li,1 Yi-qing Tao,1 Li-jiang Tao,1 Zi-ru Yang,1 Xiao-peng Zhou,1 Zhong-li Shi,2 andHui-min Tao(PMC)
(360) Gallic acid reduces cell viability, proliferation, invasion and angiogenesis in human cervical cancer cells by BING ZHAO and MENGCAI HU(PMC)
(361) Gallic acid suppresses cell viability, proliferation, invasion and angiogenesis in human glioma cell by Yong Lu,1,2 Feng Jiang,2 Hao Jiang,2 Kalina Wu,1 Xuguang Zheng,2 Yizhong Cai,3 Mark Katakowski,2 Michael Chopp,2,4 and Shing-Shun Tony To1(PMC)
(362) Antitumor effect of beta-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death. by Wang G1, Li X, Huang F, Zhao J, Ding H, Cunningham C, Coad JE, Flynn DC, Reed E, Li QQ.(PubMed)
(363) Puerarin attenuates cognitive dysfunction and oxidative stress in vascular dementia rats induced by chronic ischemia by Jing Zhang,1,2 Wenshi Guo,3 Buxian Tian,3 Menghan Sun,1 Hui Li,2 Lina Zhou,2 Xueping Liu4(PMC)
(364) The many faces of α-synuclein: from structure and toxicity to therapeutic target by Hilal A. Lashuel,1 Cassia R. Overk,2 Abid Oueslati,1 and Eliezer Masliah2,3(PMC)

(365) The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2 by N.A. Maioli,1 A.C. Zarpelon,1 S.S. Mizokami,1 C. Calixto-Campos,1 C.F.S. Guazelli,1 M.S.N. Hohmann,1 F.A. Pinho-Ribeiro,1 T.T. Carvalho,1 M.F. Manchope,1 C.R. Ferraz,1 R. Casagrande,2 and W.A. Verri, Jr1(PMC)
(366) Anti-inflammatory activity of gallic acid by Kroes BH1, van den Berg AJ, Quarles van Ufford HC, van Dijk H, Labadie RP.(PubMed)
(367) Antioxidant, anti-inflammatory, and antiproliferative activities of organic fractions from the Mediterranean brown seaweed Cystoseira sedoides by Mhadhebi L1, Laroche-Clary A, Robert J, Bouraoui A.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - Phytochemical Curcumin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                 Phytochemicals Against Dementia- Curcumin

Phytochemicals, the non nutritional parts are natural chemical constituents in plants to protect against diseases and to form color as well as other organoleptic properties. Study of Phytochemicals have emerged as a potential source to find a better treatment or cure some diseases with little or side effects or to create a synthetic equivalence for commercial profits.

Turmeric, principal curcuminoid of the popular Indian spice, is a rhizomatousherbaceous perennial plant of the ginger family, Zingiberaceae, native totropical South Asia, used in traditional herbal medicine as an anti-inflammatory agent and to treat gastrointestinal symptoms associated with irritable bowel syndrome and other digestive disorders(336). Curcumin, a phytochemical found abundant in the plant, in acidic solutions (pH <7.4) turns yellow, whereas in basic (pH > 8.6) solutions turns bright red.
1. Alzheimer's disease and Anti-inflammatory agent
a. Alzheimer's disease
Increased antioxidant and anti-inflammatory consumption such as curcumin may reduce risk of Alzheimer's disease (AD) caused by amyloid beta (Abeta) accumulation(338) through reversal of Abeta-induced cognitive deficits and neuropathology(339). The phytochemical is also found to disaggregate Abeta in preventing fibril and oligomer formation(338). According to YamagataUniversity, its synthesized curcumin analogues used pharmateutically in treatment of amyloid β aggregation also experience notable result(337). In vitro and animal models, curcumin was effective, in lowering oxidative damage, cognitive deficits, synaptic marker loss, and amyloid depositio in prevented onset of Alzheimer's disease(340).

b. Anti-inflammatory agent
Curcumin, an anti-inflammatory agent(341), in the pathogenesis of psoriasis and neurodegenerative diseases,, decreased the expression of pro-inflammatory cells signalling in response to inflammation(342)(343), in patients of ear infection and Parkinson's disease and Alzheimer'sdisease(344)(345), respectively.

2. Antioxidants
Curcumin also consisting anti-proliferative, anti-inflammatory and immunosuppressive activitie(346), in arthritis, strongly inhibited collagenase and stromely in expression at micromolar concentrations(346); in diabetes, scavenged free radicals and reduced LDL oxidation and cellular oxidative stress(347); in cancers, reduced accumulation of ROS causes of abnormal cells(348), through apoptosis(349); in neurodegenerative diseases, exerted autophagy-lysosomal activities, through removing damaged or dysfunctional proteins and cells with specific function(350) and regulating reactive oxygen species (ROS)(351)(352).
Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(336) Effects of different drying methods on the antioxidant properties of leaves and tea of ginger specie by E.W.C. Chan, Y.Y. Lim, , S.K. Wong, K.K. Lim, S.P. Tan, F.S. Lianto, M.Y. Yong(Science direct)
(337) Effects of repeated androgen treatments on metabolism and nuclear binding of androgen in the infant murine submandibular gland by Katsukawa H1, Ninomiya Y, Funakoshi M.(PubMed)
(338) Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo by Yang F1, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambegaokar SS, Chen PP, Kayed R, Glabe CG, Frautschy SA, Cole GM.(PubMed)
(339) Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology by Frautschy SA1, Hu W, Kim P, Miller SA, Chu T, Harris-White ME, Cole GM.(PubMed)
(340) Structure activity relationship study of curcumin analogues toward the amyloid-beta aggregation inhibitor by Endo H1, Nikaido Y1, Nakadate M1, Ise S1, Konno H2.(PubMed)
(341) Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation by Satoskar RR, Shah SJ, Shenoy SG.(PubMed)
(342) Curcumin inhibits imiquimod-induced psoriasis-like inflammation by inhibiting IL-1beta and IL-6 production in mice by Sun J1, Zhao Y, Hu J.(PubMed)
(343) Relevance of the anti-inflammatory properties of curcumin in neurodegenerative diseases and depression by Tizabi Y1, Hurley LL2, Qualls Z3, Akinfiresoye L4.(PubMed)
(344) Neuroprotective and neurorescue effects of a novel polymeric nanoparticle formulation of curcumin (NanoCurc™) in the neuronal cell culture and animal model: implications for Alzheimer's disease by Ray B1, Bisht S, Maitra A, Maitra A, Lahiri DK.(PubMed)
(345) Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line by Doggui S1, Sahni JK, Arseneault M, Dao L, Ramassamy C.(PubMed)
(346) The antioxidants curcumin and quercetin inhibit inflammatory processes associated with arthritis by Jackson JK1, Higo T, Hunter WL, Burt HM.(PubMed)
(347) In vitro antidiabetic and inhibitory potential of turmeric (Curcuma longa L) rhizome against cellular and LDL oxidation and angiotensin converting enzyme by Lekshmi PC1, Arimboor R1, Nisha VM1, Menon AN1, Raghu KG1.(PubMed)
(348) Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells by Chen J1, Wanming D, Zhang D, Liu Q, Kang, J.(PubMed)
(349) ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma by Thayyullathil F1, Rahman A1, Pallichankandy S1, Patel M1, Galadari S2.(PubMed)
(350) Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease. by Giordano S1, Darley-Usmar V1, Zhang J2.(PubMed)
(351) Dietary curcumin ameliorates aging-related cerebrovascular dysfunction through the AMPK/uncoupling protein 2 pathway by Pu Y1, Zhang H, Wang P, Zhao Y, Li Q, Wei X, Cui Y, Sun J, Shang Q, Liu D, Zhu Z.(PubMed)
(352) Curcumin nanoparticles attenuate neurochemical and neurobehavioral deficits in experimental model of Huntington's disease by Sandhir R1, Yadav A, Mehrotra A, Sunkaria A, Singh A, Sharma S.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - Phytochemical Tangeritin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                 Phytochemicals Against Dementia- Tangeritin

Phytochemicals, the non nutritional parts are natural chemical constituents in plants to protect against diseases and to form color as well as other organoleptic properties. Study of Phytochemicals have emerged as a potential source to find a better treatment or cure some diseases with little or side effects or to create a synthetic equivalence for commercial profits.

Tangeritin, one of the flavones, is found in tangerine and many citrus peels.
1. Neuroprotective effects
Natural antioxidant tangeretin, may be used as neuroprotective agent, for its significant effects on protection of striato-nigral integrity and functionality in patients with Parkinson's disease(327), probably through its anti-neuroinflammatory activity(328) via mitochondrial depolarization(329) in attenuated reactive oxygen species generation.

2. Antioxidants
Mature and immature calamondin (Citrus mitis Blanco) peel, containingtangeretin showed to exhibit its antioxidant(331) effects in enhancing the highest oxygen radical absorbance capacity (ORAC) and superoxide scavenging effect(330), as well as ameliorating oxidative stress causes of DNA damage(332), mammary carcinoma(333)(334) and diabetes(335).
Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(327) Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in a rat model of Parkinson's disease by Datla KP1, Christidou M, Widmer WW, Rooprai HK, Dexter DT.(PubMed)
(328) Tangeretin exerts anti-neuroinflammatory effects via NF-κB modulation in lipopolysaccharide-stimulated microglial cells by Shu Z1, Yang B1, Zhao H2, Xu B1, Jiao W1, Wang Q1, Wang Z1, Kuang H3.(PubMed)
(329) Mild mitochondrial depolarization is involved in a neuroprotective mechanism of Citrus sunki peel extract by Wu JJ1, Cui Y, Yang YS, Jung SC, Hyun JW, Maeng YH, Park DB, Lee SR, Kim SJ, Eun SY.(PubMed)
(330) Antioxidant activity and effective compounds of immature calamondin peel by Yu MW1, Lou SN, Chiu EM, Ho CT.(PubMed)
(331) Polymethoxylated flavones, flavanone glycosides, carotenoids, and antioxidants in different cultivation types of tangerines ( Citrus reticulata Blanco cv. Sainampueng) from Northern Thailand by Stuetz W1, Prapamontol T, Hongsibsong S, Biesalski HK.(PubMed)
(332) Tangeretin ameliorates oxidative stress in the renal tissues of rats with experimental breast cancer induced by 7,12-dimethylbenz[a]anthracene by Lakshmi A1, Subramanian SP2.(PubMed)
(333) Chemotherapeutic effect of tangeretin, a polymethoxylated flavone studied in 7, 12-dimethylbenz(a)anthracene induced mammary carcinoma in experimental rats. by Lakshmi A1, Subramanian S2.(PubMed)
(334) Tangeretin, a citrus pentamethoxyflavone, exerts cytostatic effect via p53/p21 up-regulation and suppresses metastasis in 7,12-dimethylbenz(α)anthracene-induced rat mammary carcinoma by Arivazhagan L1, Sorimuthu Pillai S2.(PubMed)
(335) Effect of tangeretin, a polymethoxylated flavone on glucose metabolism in streptozotocin-induced diabetic rats. by Sundaram R1, Shanthi P2, Sachdanandam P3.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - Phytochemical Naringenin

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                 Phytochemicals Against Dementia- Naringenin

Phytochemicals, the non nutritional parts are natural chemical constituents in plants to protect against diseases and to form color as well as other organoleptic properties. Study of Phytochemicals have emerged as a potential source to find a better treatment or cure some diseases with little or side effects or to create a synthetic equivalence for commercial profits.

Naringenin, a flavanone, belonging to the red, blue, purple pigments of Flavonoids (polyphenols) found predominantly in citrus fruits is considered as one of powerful antioxidant with many health benefits.
1. Antioxidant, free radical scavenging
Naringin showed to reduce DNA damage through its antioxidant capacities in scavenging free radicals hydroxyl and superoxide(317). Cognitively,naringenin ameliorated Alzheimer's disease (AD)-type neurodegeneration(318) by improving learning and memory ability of patient with early onset of the diseases(319). Pharmacologically, the phytochemical was found to be a potential anticancer, antimutagenic, anti-inflammatory, antiproliferative and antiatherogenic agent(320).

2. Anti-inflammatory effects(320)
Neuroinflammation is considered as a constant event in Alzheimer's disease (AD), with no evidences for its direct involvement in development(322). In diabetic mice model, naringenin exhibited its anti inflammatory activity in lowering blood glucose and urea nitrogen, increasing insulin level and
creatinine clearance(321), probably through inhibition of iNOS protein and anti inflammatory pathways(323).

3. Immunity
Adaptive and innate immune deficit were shown to associate with cognitive dysfunction in patients with AD and mild cognitive impairment (MCI)(325).Naringenin, stimulated the production T cells in regulation of the immune system, and in suppression of allergies and autoimmune diseases(324) which are considered as Alzheimer's and Parkinson's disease variants(326).
Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References

The holistic Prevention, Management and Treatment of Dementia - Phytochemical Gingerole

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                 Phytochemicals Against Dementia- Gingerole

Phytochemicals, the non nutritional parts are natural chemical constituents in plants to protect against diseases and to form color as well as other organoleptic properties. Study of Phytochemicals have emerged as a potential source to find a better treatment or cure some diseases with little or side effects or to create a synthetic equivalence for commercial profits.

Gingerole, is also known as gingerol, a phytochemical of flavonoids (polyphenols) found in fresh ginger. and in variety of other plants. The herb has been used for treatment of nausea and vomiting of pregnancy, motion sickness, rheumatoid arthritis, relieve migraine, etc. in folk medicine.
1. Antioxidant and anti-inflammatory effects
Chemical constituents of Zingiber officinale Rosc.(Zingiberaceae) showed to attenuate oxidative stress, through its scavenging, and inhibiting superoxide and hydroxyl radicals of ROS species(310), via nephroprotective effect on mediation of oxidative stress, inflammatory processes, and renal dysfunction(311).

2. Dementia
Ginger(70% aqueous/methanolic extract of dried ginger (Zo.Cr)) besides induced spasmolytic activity in stomach fundus in treating dementia in South Asia, it also inhibited butyrylcholinesterase (BuChE) in improvement of cognitive performance patients with dementia(315) and vascular dementia(VaD)(315), probably through cholinergic anti-inflammatory pathway in reduced production of amyloid-β(316).
Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(314) Muscarinic, Ca(++) antagonist and specific butyrylcholinesterase inhibitory activity of dried ginger extract might explain its use in dementia by Ghayur MN1, Gilani AH, Ahmed T, Khalid A, Nawaz SA, Agbedahunsi JM, Choudhary MI, Houghton PJ.(PubMed)
(315) [Effect of AChE and BuChE inhibition by rivastigmin in a group of old-old elderly patients with cerebrovascular impairment (SIVD type)].[Article in Italian] by Servello A1, Andreozzi P, Bechini F, De Angelis R, Pontecorvo ML, Vulcano A, Cerra E, Vigliotta MT, Artini M, Selan L, Ettorre E.(PubMed)
(316) Selective acetyl- and butyrylcholinesterase inhibitors reduce amyloid-β ex vivo activation of peripheral chemo-cytokines from Alzheimer's disease subjects: exploring the cholinergic anti-inflammatory pathway by Reale M, Di Nicola M, Velluto L, D'Angelo C, Costantini E, Lahiri DK, Kamal MA, Yu QS, Greig NH1.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - Phytochemicals Rosemarinol

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                 Phytochemicals Against Dementia- Rosemarinol

Phytochemicals, the non nutritional parts are natural chemical constituents in plants to protect against diseases and to form color as well as other organoleptic properties. Study of Phytochemicals have emerged as a potential source to find a better treatment or cure some diseases with little or side effects or to create a synthetic equivalence for commercial profits.

C.1. Rosemarinol
Rosemarinol is a phytochemical monophenols, found in essential oil of labiate herbs like rosemary and in variety of other plants.
1. Retard autoxidation
Rosemary extract rich in carnosic acid showed a significantly retarded autoxidation, in the fish oil undergoes microencapsulation process(307).

2. Anti-inflammatory effects
The extract of rosemary leaves from supercritical fluid extraction showed a high inhibitory effect on lipid peroxidation, through suppression of the LPS-induced production of nitric oxide (NO)(308) and maintaining oxidative stability(313)

3. Antioxidant defences
Rosemary extract enhanced antioxidant defences and improved antioxidant status in aged rats in attenuation of lipid peroxidation and ROS levels through its antioxidant enzyme activity(309). The extract also showed to exhibit its antioxidant effect against the proliferation of irregular cell growth such as human leukemia and breast carcinoma cells(312).
Chinese Food Therapy
The Best Way to prevent, treat your disease, including dementia 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

References
(307) Chemical stabilization of oils rich in long-chain polyunsaturated fatty acids during storage by Pop F1.(PubMed)
(308) Anti-inflammatory effects of supercritical carbon dioxide extract and its isolated carnosic acid from Rosmarinus officinalis leaves by Kuo CF1, Su JD, Chiu CH, Peng CC, Chang CH, Sung TY, Huang SH, Lee WC, Chyau CC.(PubMed)
(309) Protective effect of supercritical fluid rosemary extract, Rosmarinus officinalis, on antioxidants of major organs of aged rats by Posadas SJ1, Caz V, Largo C, De la Gándara B, Matallanas B, Reglero G, De Miguel E.(PubMed)
(310) Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol by Dugasani S1, Pichika MR, Nadarajah VD, Balijepalli MK, Tandra S, Korlakunta JN.(PubMed)
(311) Gingerol fraction from Zingiber officinale protects against gentamicin-induced nephrotoxicity. by Rodrigues FA1, Prata MM, Oliveira IC, Alves NT, Freitas RE, Monteiro HS, Silva JA, Vieira PC, Viana DA, Libório AB, Havt A.(PubMed)
(312) Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis by Cheung S1, Tai J.(PubMed)
(313) Effects of "nitrendipine" on nitrous oxide anesthesia, tolerance, and physical dependence by Dolin SJ1, Little HJ.(PubMed)

The holistic Prevention, Management and Treatment of Dementia - Common antioxidants (scavengers) Vitamin E

Kyle J. Norton (Scholar) 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                 Dementia

Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.

                 Common antioxidants (scavengers) Vitamin E

The expression of added to a mixture in order to remove or de-activate impurities and unwanted oxygen in the cellular level for reduced risk of oxidative stress defence in plants and animals.

b. Vitamin C
Vitamin C, presencted in aqueous compartments (e.g. cytosol, plasma, and other body fluids)(292) plays an important role in synthesis of collagen, carnitine, catecholamine and the neurotransmitter norepinephrine(293). As an water soluble vitamin, vitamin C can be easily carried in blood, operated in many parts of body. By recycling vitamin E, vitamin C also helps to fight against forming of free radicals(294). By enhancing the immune system(295)(296), it promotes against the microbial and viral(298) and irregular cell growth causes of infection and inflammation(297).
Vitamin C also is a free radical scavenger in inhibiting pollution cause of oxidation(299).

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References
(301) Vitamin E: action, metabolism and perspectives by Herrera E1, Barbas C.(PubMed)
(302) Polymeric films loaded with vitamin E and aloe vera for topical application in the treatment of burn wounds by Pereira GG1, Guterres SS1, Balducci AG2, Colombo P2, Sonvico F3.(PubMed)
(303) Function of vitamin E in physical exercise: a review by Gerster H1.(PubMed)
(304) Oxidative stress and damage induced by abnormal free radical reactions and IgA nephropathy by Chen JX1, Zhou JF, Shen HC.(PubMed)
(305) Effects of vitamin E on cognitive performance during ageing and in Alzheimer's disease by La Fata G1, Weber P2, Mohajeri MH3.(PubMed)
(306) Redox modulation of cellular stress response and lipoxin A4 expression by Coriolus versicolor in rat brain: Relevance to Alzheimer's disease pathogenesis. by Trovato A1, Siracusa R2, Di Paola R2, Scuto M1, Fronte V1, Koverech G1, Luca M1, Serra A3, Toscano MA1, Petralia A3, Cuzzocrea S2, Calabrese V4.(PubMed)