Most Common Diseases of elder: The Clinical Trials and Studies of Musculo-Skeletal disorders: Osteoporosis: The Splendid and Preventive foods by herbal and TCM medicine specialists

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                Osteoporosis

Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and often associated with senescence in vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(6).

                               The Treatment

B. In herbal  and traditional Chinese medicine perspective

4. The Preventive foods
4.1. Dry plum
Dry plum is best known for its natural laxative sorbitol used for treatment of constipation and considered as a best candidate for treatment against osteoporosis and osteopenia due to the presence of antioxidants hydroxycinnamic acids(434) and anthocyanins(435).
Some studies of the bone-protective properties of dried plum suggested that the fruit significantly increased the BMD of the ulna and spine through its antioxidant effects on increased RANKL and osteoprotegerin (OPG) levels in comparison with the control group(436). In postmenopausal women, daily intake of dried plum (100 g/d) significantly increased BMD of ulna and spine through suppressed rate of bone turn over in comparison with the same intake as of apple(437), according to
the Florida State University

Dr. Hooshmand S. and the research team at the San Diego State University and Florida State University suggested ".... the positive effects of dried plum on bone are in part due to the suppression of RANKL production, the promotion of OPG and the inhibition of sclerostin..." of that have a direct control on bone formation via the production of sclerostin and bone resorption(438).

4.2. Apple
Apple, one of the most widely cultivated tree fruit for its nutrients, is the pomaceous fruit of the apple tree, a species of the rose family Rosaceae, originated in Central Asia. The fruit has long been known for its benefits in cardiovascular protective effects(439).  Dihydrochalcone phloretin, an antioxidant found in apple tree leaves, exert protective effect against estrogen deficiency-induced osteoclastogenic resorption, through its activities involved RANKL-differentiatiation in mature osteoclasts(440). According to Unité des Maladies Métaboliques et Micronutriments, phloridzin, an other apple antioxidant polyphenol improved aging and sex hormones deficiency causes of inflammatory and oxidant conditions, inducing pathogenesis of osteoporosis, through promoting inflammation markers and bone resorption(441).

4.3. Tomato
Tomato is a red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of the recent discovery of its antioxidant, such as lycopene in reduced risk of prostate(442) and cancers(443) and cardiovascular disease(443), tomato is grown world wide for commercial purpose and often in green house.

Dr. Sołtysiak P and Dr. Folwarczna J. in the assessement of the effectiveness of carotenoid pigment, lycopene suggested that the phytochemical exhibit a favorable affect the skeletal system such as osseous tissue through inhibited bone resorption(444), the formation of ROS-secreting osteoclasts(445), formation of tartrate-resistant acid phosphatase  + multinucleated osteoclasts(445) of that can result in reduced risk of osteoporosis.

In animal model, lycopene decreased oxidative stress of which has a inversely correlated with BMD and improved BMD through facilitated bone formation and inhibited bone resorption(446).

4.4. Dairy and calcium fortified products

Intake regularly of Dairy(The prevention and management: the Diet-1) and calcium fortified products(The prevention and management: the Diet-5) are both recommended by herbal medicine  for its benefits in induced calcium absorption because of the presence of vitamin D3, but not in traditional Chinese medicine. TCM views dairy products with a extreme dampness presentation(446a) of which induce production of phlegm(446b) causes of many forms of diseases.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) Osteoporosis(Life extension)
(4) Hormone and bone by Francisco Bandeira1, Marise Lazaretti-Castro2, John P. Bilezikian3
(5) Growth hormone and bone by Ohlsson C1, Bengtsson BA, Isaksson OG, Andreassen TT, Slootweg MC.(PubMed)

(6) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)

(434) Oral administration of phytocomponent p-hydroxycinnamic acid prevents bone loss in ovariectomized rats by Yamaguchi M1, Lai YL, Uchiyama S, Nakagawa T.(PubMed)

(435) Nutraceutical and antioxidant effects of a delphinidin-rich maqui berry extract Delphinol®: a review by Watson RR1, Schönlau F.(PubMed)

(436) The effect of dried plum on serum levels of receptor activator of NF-κB ligand, osteoprotegerin and sclerostin in osteopenic postmenopausal women: a randomised controlled trial by Hooshmand S1, Brisco JR1, Arjmandi BH2.(PubMed)

(437) Comparative effects of dried plum and dried apple on bone in postmenopausal women by Hooshmand S1, Chai SC, Saadat RL, Payton ME, Brummel-Smith K, Arjmandi BH.(PubMed)

(438) The effect of dried plum on serum levels of receptor activator of NF-κB ligand, osteoprotegerin and sclerostin in osteopenic postmenopausal women: a randomised controlled trial by Hooshmand S1, Brisco JR1, Arjmandi BH2.(PubMed)

(439) Daily apple versus dried plum: impact on cardiovascular disease risk factors in postmenopausal women by Chai SC1, Hooshmand S, Saadat RL, Payton ME, Brummel-Smith K, Arjmandi BH.(PubMed)

(440) Phloretin promotes osteoclast apoptosis in murine macrophages and inhibits estrogen deficiency-inducedosteoporosis in mice by Lee EJ1, Kim JL1, Kim YH1, Kang MK1, Gong JH1, Kang YH2.(PubMed)

(441) Prevention of bone loss by phloridzin, an apple polyphenol, in ovariectomized rats under inflammation conditions by Puel C1, Quintin A, Mathey J, Obled C, Davicco MJ, Lebecque P, Kati-Coulibaly S, Horcajada MN, Coxam V.(PubMed)

(442) Lycopene/tomato consumption and the risk of prostate cancer: a systematic review and meta-analysis of prospective studies by Chen J1, Song Y, Zhang L.(PubMed)

(443) Role of antioxidant lycopene in cancer and heart disease by Rao AV1, Agarwal S.(PubMed)

(444) [Effects of lycopene on the skeletal system].[Article in Polish by Sołtysiak P1, Folwarczna J1.(PubMed)

(445) Lycopene I--effect on osteoclasts: lycopene inhibits basal and parathyroid hormone-stimulated osteoclast formation and mineral resorption mediated by reactive oxygen species in rat bone marrow cultures by Rao LG1, Krishnadev N, Banasikowska K, Rao AV.(PubMed)

(446) Lycopene intake facilitates the increase of bone mineral density in growing female rats by Iimura Y1, Agata U, Takeda S, Kobayashi Y, Yoshida S, Ezawa I, Omi N.(PubMed)

(446a) The Chinese Medicine Diet, Article by Margaret. May 1, 2010

Most Common Diseases of elder: The Clinical Trials and Studies of Musculo-Skeletal disorders: Osteoporosis: The Marvelous Supplements , according herbal and TCM medicine specialist

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                Osteoporosis

Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and often associated with senescence in vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(6).

                               The Treatment

B. In herbal  and traditional Chinese medicine perspective

5. The Supplements for osteoporosis
5.1. Phyto-estrogens(women only)
Phyto-estrogens found in plants weaker types of estrogen hormone with estrogenic or/and antiestrogenic effects in comparison to natural estrogen hormones(447). In perimenopausal or postmenopausal womenwomen intake of phytoestrogen is found to associate to vasomotor symptoms relief(448). Genistein, one of the best known phytoestrogen exhibited anti-resorptive effects on bone metabolism, anti bone loss by enhanced osteoblastic production of osteoprotegerin (OPG)(450).
Dr. Malinova M. said" phytoetrogens and vitamin D administered in a dose-dependent manner effectively prevents bone loss in postmenopausal women and reduces the incidence of fractures"(449). In fact, the effects of phytochemical in reduced risk of osteoporosis may also be depended on genetic influence.  According to the Nanchang University, the effects of dietary phytoestrogens on bone mineral density (BMD)postmenopausal women may be varied with ERα gene(451).

5.2. Glucosamine

Glucosamine, a compound of the simple sugar glucose and the amino acid glutamine, is a precursor for glycosaminoglycans(194,452), a major component of joint cartilage(195,453). As a Collagen peptides, glucosamine has produced a favorable effect on bone health and cartilage tissue(454).
According to the study by the Queen's University, oral administration of glucosamine at 200-mg/kg dose for 6 months showed a significant preventive effects on mineral content and some biomechanical properties(455) of which improve bone and joint disorder. Dr. Anastassiades T and the research team said" N-butyryl glucosamine (GlcNBu) can be positioned between nutriceuticals and pharmaceuticals for the prevention and treatment of osteoporosis"(455).

In senescence-accelerated OXYS rats as model of osteoporosis, glucosamine alendronate (GA) alone or/and icombination with dihydroquercetin (DHQ) increased BMD and the level of osteocalcin, according to the study by Institute of Cytology & Genetics of the Siberian Branch of Russian Academy of Sciences(456)

 In deed, treatment of glucosamine sulfate, chondroitin sulfate, hyaluronic acid, collagen hydrolysate, or nutrients, such as antioxidants and omega-3 fatty acids showed to prevent cartilage degeneration in patient with bone and joint disorder , according to study(195, 457).

5.3. Chondroitin
Sulfated glycosaminoglycan (GAG), found in cartilage around joints in the body is a chemical composed of alternating sugars (N-acetylgalactosamine and glucuronic acid).
Chondroitin sulfate (CS), a glycosaminoglycan (GAG) and functional component in proteoglycans of cartilaginous tissues may be a nutraceutical ingredient commonly utilized in fighting against arthritis, osteoarthrosis, and sometimes osteoporosis(458), probably through activation of Cathepsin K (CatK), a major lysosomal collagenase produced by osteoclasts, in bone resorption.and promoted efficient collagen degradation(459). Given all the positive information of Cathepisn K in bone health, Dr. Li Z and the research team said" targeting cathepsin K complex formation would be an effective and specific treatment for diseases with excessive bone resorption such as osteoporosis'(460).
Dr. Watanabe R and Okazaki R. said" Cathepsin K,.....markedly reduced bone resorption with a transient reduction in bone formation, thus resulted in a robust increase in both trabecular and cortical BMD in osteoporotics"(461).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) Osteoporosis(Life extension)
(4) Hormone and bone by Francisco Bandeira1, Marise Lazaretti-Castro2, John P. Bilezikian3
(5) Growth hormone and bone by Ohlsson C1, Bengtsson BA, Isaksson OG, Andreassen TT, Slootweg MC.(PubMed)

(6) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)

(447) Phytoestrogens in Functional Foods edited by Fatih Yildiz, 2005, 336 pages, CRC Press, Boca Raton, FL by Alison M Duncan( American Society for Clinical Nutrition)
(448) Phytoestrogens for menopausal vasomotor symptoms by Lethaby A1, Marjoribanks J, Kronenberg F, Roberts H, Eden J, Brown J.(PubMed)
(449) [PHYTOESTROGENS AND VITAMIN D FOR BONE HEALTH IN MENOPAUSAL TRANSITION].[Article in Bulgarian] by Malinova M.(PubMed)

(450) Phytoestrogen genistein stimulates the production of osteoprotegerin by human trabecular osteoblasts by Viereck V1, Gründker C, Blaschke S, Siggelkow H, Emons G, Hofbauer LC.(PubMed)

(451) Association between dietary phytoestrogen intake and bone mineral density varied with estrogen receptor alpha gene polymorphisms in southern Chinese postmenopausal women by Luo D1, Liu Y, Zhou Y, Chen Z, Yang L, Liu Y, Xu Q, Xu H, Kuang H, Huang Q, He M, Peng W.(PubMed)

(452)
(453)
(454)[Bone and Nutrition. Functional foods for bone and cartilage tissues : Evidence for the action of collagen peptides].[Article in Japanese]by Kimira Y1, Mano H.(PubMed)
(455) N-acylated glucosamines for bone and joint disorders: effects of N-butyryl glucosamine on ovariectomized rat bone by Anastassiades T1, Rees-Milton K, Xiao H, Yang X, Willett T, Grynpas M.(PubMed)
(456) Efficacy of glucosamine alendronate alone & in combination with dihydroquercetin for treatment of osteoporosisin animal model by Muraleva NA1, Ofitserov EN, Tikhonov VP, Kolosova NG.(PubMed)
(457)

(458) Medical Gains of Chondroitin Sulfate upon Fucosylation by Pomin VH1.(PubMed)

(459) Chondroitin sulfate promotes activation of cathepsin K by Lemaire PA1, Huang L2, Zhuo Y2, Lu J3, Bahnck C1, Stachel SJ4, Carroll SS1, Duong LT5.(PubMed)(460) Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate by Li Z1, Hou WS, Escalante-Torres CR, Gelb BD, Bromme D.(PubMed)
(461) [Reducing bone resorption by cathepsin K inhibitor and treatment of osteoporosis].[Article in Japanese]by Watanabe R1, Okazaki R.(PubMed)

Most Common Diseases of elder: The Clinical Trials and Studies of Musculo-Skeletal disorders: Osteoporosis: The effectiveness of Oilve oil, according herbal and TCM medicine specialist

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                Osteoporosis

Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and often associated with senescence in vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(6).

                               The Treatment

B. In herbal  and traditional Chinese medicine perspective

3. Nuts and seeds Olive
Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil.

Olive Oil: Fat Content
1. Saturated fats
a. Palmitic acid
b. Stearic acid
c. Arachidic acid
d. ehenic acid
e. Myristic acid
f. Lignoceric acid
2. Unsaturated fat3. Monounsaturated fats
a. Oleic acid
b. Palmitoleic acid
3. Polyunsaturated fats
a. Linoleic acid
b. Linolenic acid

Monounsaturated fatty acids found abundantly in olive oil, has found to regulate adipose tissue inflammation by altering adipocyte signalling pathways and the secretion of proinflammatory cytokines(422) of that may induced risk of osteoporosis as mentioned.

The richest source of oleoyl serin of olive oil may contribute to lowered prevalence of osteoporosis if consumed in high amount, Dr Bradshaw HB and Leishman E. suggested(423).

In vertebra and tibia in ovariectomized rats, black olive hydroalcoholic extract effectively lower the quantitative changes of the bone structure and prevented bone loss in this osteoporosis animal model, through decreased osteoclast cells in vertebra and tibia(424) and increased in the cortical bone thickness (CBT) and the trabecular bone thickness (TBT)(425).

In deed, according to the study by the Xiamen University, the effectiveness of olive oil in exhibition of anti-osteoporosis is due to its function in significantly increased BMD and decreased phosphatase, alkaline phosphatase, IL-6, MDA, and nitrate levels(426).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) Osteoporosis(Life extension)
(4) Hormone and bone by Francisco Bandeira1, Marise Lazaretti-Castro2, John P. Bilezikian3
(5) Growth hormone and bone by Ohlsson C1, Bengtsson BA, Isaksson OG, Andreassen TT, Slootweg MC.(PubMed)

(6) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)

(422) SCD1 mediates the influence of exogenous saturated and monounsaturated fatty acids in adipocytes: Effects on cellular stress, inflammatory markers and fatty acid elongation by Ralston JC1, Metherel AH2, Stark KD3, Mutch DM4.(PubMed)

(423) Levels of bioactive lipids in cooking oils: olive oil is the richest source of oleoyl serine by Bradshaw HB, Leishman E.(PubMed)

(424) Stereological study of the effect of black olive hydroalcoholic extract on osteoporosis in vertebra and tibia in ovariectomized rats by Noorafshan A1, Dabbaghmanesh MH, Tanideh N, Koohpeyma F, Rasooli R, Hajihoseini M, Bakhshayeshkaram M, Hosseinabadi OK.(PubMed)

(425) Olive oil effectively mitigates ovariectomy-induced osteoporosis in rats by Saleh NK1, Saleh HA.(PubMed)

(426) Olive oil in the prevention and treatment of osteoporosis after artificial menopause by Liu H1, Huang H1, Li B1, Wu D1, Wang F1, Zheng Xh1, Chen Q1, Wu B1, Fan X1.(PubMed)

Most Common Diseases of elder: The Clinical Trials and Studies of Musculo-Skeletal disorders: Osteoporosis: The miracle of Salmon according herbal and TCM medicine specialist

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                Osteoporosis

Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and often associated with senescence in vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(6).

                               The Treatment

B. In herbal  and traditional Chinese medicine perspective

2. The miracle of Salmon
Salmon is the common name for Salmonidae. They are anadromous, born in fresh water, migrate to the ocean, then travel thousands of miles in the deep sea cold water throughout their life cycle and within to five years returning to the exacted location where they were born to reproduce and die.

Nutrients
1. Protein
2. Omega-3 fatty acids
3. B vitamins
4. Vitamin D
5. Astaxanthin
is a potent antioxidant that stimulates the development of healthy fish nervous systems and enhances the fish's fertility and growth rate.
6. Selenium
7. Tryptophan
8. Magnesium
9. Phosphorus
10. Etc.

Intake of salmon calcitonin, a hormone produced by the thyroid gland of salmon or a synthetic polypeptide of the same sequence found in salmon(360,415) has shown to reduce vertebral crush fractures and bone pain and considered for prevention and treatment of postmenopausal osteoporosis(416). In a randomized trial of  men with idiopathic osteoporosis, nasal spray salmon calcitonin exhibited a significantly pronounced suppression of bone resorption markers by increasing lumbar BMD and reducing bone turnover in men with idiopathic osteoporosis(417) and affecting serum and synovial fluid bone formation and resorption markers in osteoporosis patients(418). Dr Dexue L and Dr. Yueyue Z. said" salmon calcitonin of 50 IU each time, subcutaneous injection 1 time every 3 days, for 3 months is a reasonable solution may be effective for treatment of elderly women with type 2 diabetes and osteoporosis"(419).
Further more, in a randomized, placebo-controlled trial, treatment with salmon calcitonin increased lumbar spine BMD and improved low bone mass and reduced fracture risk in postmenopausal women(420).

The high amount of Omega 3 fatty acid also make salmon of the dietary nutrients for skeleton health including prevention reduced risk of progression of osteoporosis(421).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) Osteoporosis(Life extension)
(4) Hormone and bone by Francisco Bandeira1, Marise Lazaretti-Castro2, John P. Bilezikian3
(5) Growth hormone and bone by Ohlsson C1, Bengtsson BA, Isaksson OG, Andreassen TT, Slootweg MC.(PubMed)
(6) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)

(360)

(416) Salmon calcitonin (Miacalcic) nasal spray in prevention and treatment of osteoporosis by Gennari C1.(PubMed)

(417) A randomized trial of nasal spray salmon calcitonin in men with idiopathic osteoporosis: effects on bone mineral density and bone markers by Trovas GP1, Lyritis GP, Galanos A, Raptou P, Constantelou E.(PubMed)

(418) Effects of salmon calcitonin treatment on serum and synovial fluid bone formation and resorption markers inosteoporosis patients by Atbinici H1, Sipahioğlu S2, Aksoy N3, Baykara İ2, Işıkan UE2.(PubMed)

(419) Salmon calcitonin in the treatment of elderly women with type 2 diabetes complicated with osteoporosis by Dexue L1, Yueyue Z2.(PubMed)

(420) Efficacy and safety of oral recombinant calcitonin tablets in postmenopausal women with low bone mass and increased fracture risk: a randomized, placebo-controlled trial by Binkley N1, Bone H, Gilligan JP, Krause DS.(PubMed)

(421) A systematic review of omega-3 fatty acids and osteoporosis by Tonya S. Orchard,1 Xueliang Pan,2 Fern Cheek,3 Steven W. Ing,4 and Rebecca D. Jackson4(PMC)

Most Common Diseases of elder: The Clinical Trials and Studies of Musculo-Skeletal disorders: Osteoporosis: Top foods to reduce risk of inflammation, according herbal and TCM medicine specialist

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                Osteoporosis

Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and often associated with senescence in vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(6).

                               The Treatment

B. In herbal  and traditional Chinese medicine perspective

B.2. Diet modification according herbal and TCM medicine specialist

1. Top foods to reduce risk of inflammation
Epidemiological studiesin human and animal have insisted of pro-inflammatory cytokines as primary mediators of the accelerated bone loss at menopause in which interfering the activation of osteoclasts and stimulators of osteoclastic bone resorption(391).

According to the study lead by the St Vincent's University Hospital Dublin, osteoporosis is found to associate to abnormal bone turnover, systemic inflammation and ultimately increased bone loss and fractures(392)

Dr. Jakob F. and research team at the Universität Würzburg said "....impaired inosteoporosis and during aging. Bone resorption is enhanced by chronic inflammation while bone formation is altered by rising levels of inhibitors in the aging organism,.."(393)

1. 1. Garlic
Garlic, one of the top food with property on modulation of the pro-inflammatory cytokines associated to postmenopausal bone loss(394) due to aging in reduced production of estrogen. The recent study by the Presidency College, suggested that oil extract of garlic promotes and preserve skeletal health in attenuate bone loss by expression of estrogenic effects through reduced oxidative stress of peritoneal macrophages, lymphocytes and serum interleukins(395) and enhanced intestinal transference of calcium(396).
In ovariectomized rat model, garlic oil in comparison with lovastatin exhibited anti bone loss its reflected onhigher bone densities and higher bone mineral contents(397) as well as induced positively in suppressing ovariectomy-bone resorption(398)..

1.2. Turmeric
Turmeric with the similar property as garlic in enhancing immune system fighting against inflammation caused by either free radicals and foreign invasion(399)(400). Used in tradition medicine to relieve menopausal symptoms, the antioxidant also promoted production of bone structural genes, increased the osteoprotegerin to RANKL ratio and supported mineralization more efficiently, according to the Mahidol University(401), as well as reduced trabecular bone loss and prevented deterioration of bone microarchitecture by suppressing the rate of bone turnover(402) probably due to its phytoestrogenic effects(401). DR. Shishodia S and the research team at the The University of Texas M. D. Anderson Cancer Center said " The efficacy, pharmacologic safety, and cost effectiveness of curcuminoids prompt us to "get back to our roots.""(403) due to its effects for treatment of several diseases(403).

1.3. Green tea
Green tea, a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years, is considered as one the top antioxidants and anti inflammatory agent (404)(405). Epidemiological studies suggested that green tea benefited body composition and improved bone microstructure and strength(406), exhibited osteogenic differentiation(407) and reduced risk of osteoporosis(408).

1.4. Shiitake mushrooms
Shiitake mushroom is an edible mushroom with anti inflammatory activity through activated the immune effects and enhance cell resistance to bacterial infections(409).

According to the study by the College of Veterinary Medicine, D3 found in mushroom improved osteoporosis-like symptoms through it effects on improved bone mineralization by inducing the expression of calcium-absorbing genes found in the duodenum and kidney(410).

1.5. Onion

Onion, with the same properties as of garlic, also consisted the anti osteoporosis property through its effects on increased bone density in perimenopausal and postmenopausal women 50 years and older(411). The Universitätsspital/Inselspital Bern. on the expression of Osteoporosis diet suggested that intake of vegetables from onion family inhibits bone resorption in a dose-dependent manner(412). Dr. Tang CH and the research team at the China Medical University said "water solution of onion crude powder inhibits osteoclastogenesis from co-cultures of bone marrow stromal cells and macrophage cells via attenuation of RANKL-induced ERK, p38 and NF-kappaB activation"(413).

Arthritis Is Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)

(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)

(3) Osteoporosis(Life extension)

(4) Hormone and bone by Francisco Bandeira1, Marise Lazaretti-Castro2, John P. Bilezikian3

(5) Growth hormone and bone by Ohlsson C1, Bengtsson BA, Isaksson OG, Andreassen TT, Slootweg MC.(PubMed)

(6) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)

(391) Osteoporosis and inflammation by Mundy GR1.(PubMed)

(392) An association between abnormal bone turnover, systemic inflammation, and osteoporosis in patients with chronic pancreatitis: a case-matched study by Duggan SN1, Purcell C1, Kilbane M2, O'Keane M2, McKenna M2, Gaffney P3, Ridgway PF1, Boran G3, Conlon KC4.(PubMed)

(393) [Regulation of bone metabolism in osteoporosis : Novel drugs for osteoporosis in development].[Article in German]by Jakob F1, Genest F2, Baron G2, Stumpf U3, Rudert M2, Seefried L2.(PubMed)

(394) The effect of garlic tablet on pro-inflammatory cytokines in postmenopausal osteoporotic women: a randomized controlled clinical trial by Mozaffari-Khosravi H1, Hesabgar HA, Owlia MB, Hadinedoushan H, Barzegar K, Fllahzadeh MH.(PubMed)

(395) Role of peritoneal macrophages and lymphocytes in the development of hypogonadal osteoporosis in an ovariectomized rat model: possible phytoestrogenic efficacy of oil extract of garlic to preserve skeletal health by Mukherjee M1, Das AS, Das D, Mukherjee S, Mitra S, Mitra C.(PubMed)

(396) Role of oil extract of garlic (Allium sativum Linn.) on intestinal transference of calcium and its possible correlation with preservation of skeletal health in an ovariectomized rat model of osteoporosis by Mukherjee M1, Das AS, Das D, Mukherjee S, Mitra S, Mitra C.(PubMed)

(397) Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison with the effects of lovastatin and 17beta-estradiol by Mukherjee M1, Das AS, Das D, Mukherjee S, Mitra S, Mitra C.(PubMed)

(398) Prevention of bone loss by oil extract of garlic (Allium sativum Linn.) in an ovariectomized rat model ofosteoporosis by Mukherjee M1, Das AS, Mitra S, Mitra C.(PubMed)

(399) Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa) by Chainani-Wu N1.(PubMed)

(400) Antioxidant and anti-inflammatory properties of curcumin by Menon VP1, Sudheer AR.(PubMed)

(401) A diarylheptanoid phytoestrogen from Curcuma comosa, 1,7-diphenyl-4,6-heptadien-3-ol, accelerates human osteoblast proliferation and differentiation by Tantikanlayaporn D1, Robinson LJ, Suksamrarn A, Piyachaturawat P, Blair HC.(PubMed)

(402) Bone sparing effect of a novel phytoestrogen diarylheptanoid from Curcuma comosa Roxb. in ovariectomized rats by Tantikanlayaporn D1, Wichit P, Weerachayaphorn J, Chairoungdua A, Chuncharunee A, Suksamrarn A, Piyachaturawat P.(PubMed)

(403) Curcumin: getting back to the roots by Shishodia S1, Sethi G, Aggarwal BB.(PubMed)

(404) The acute effects of green tea and carbohydrate coingestion on systemic inflammation and oxidative stress during sprint cycling by Suzuki K1, Takahashi M1, Li CY2, Lin SP3, Tomari M1, Shing CM4, Fang SH5.(PubMed)

(405) Green tea polyphenols change the profile of inflammatory cytokine release from lymphocytes of obese and lean rats and protect against oxidative damage by Molina N1, Bolin AP1, Otton R2.(PubMed)

(406) Green tea supplementation benefits body composition and improves bone properties in obese female rats fed with high-fat diet and caloric restricted diet by Shen CL1, Han J2, Wang S3, Chung E4, Chyu MC5, Cao JJ6(PubMed)

(407) Epigallocatechin-3-gallate (EGCG) as a pro-osteogenic agent to enhance osteogenic differentiation of mesenchymal stem cells from human bone marrow: an in vitro study by Jin P1, Wu H, Xu G, Zheng L, Zhao J.(PubMed)

(408) Dietary patterns and osteoporosis risk in postmenopausal korean women by Park SJ1, Joo SE, Min H, Park JK, Kim Y, Kim SS, Ahn Y.(PubMed)

(409) A natural formulation (imoviral™) increases macrophage resistance to LPS-induced oxidative and inflammatorystress in vitro by Menghini L1, Leporini L1, Pintore G2, Ferrante C1, Recinella L1, Orlando G1, Vacca M1, Brunetti L1.(PubMed)

(410) Dietary calcium and vitamin D2 supplementation with enhanced Lentinula edodes improves osteoporosis-like symptoms and induces duodenal and renal active calcium transport gene expression in mice by Lee GS1, Byun HS, Yoon KH, Lee JS, Choi KC, Jeung EB.(PubMed)

(411) The association between onion consumption and bone density in perimenopausal and postmenopausal non-Hispanic white women 50 years and older by Matheson EM1, Mainous AG 3rd, Carnemolla MA.(PubMed)

(412) [Osteoporosis diet].[Article in German] by Morselli B1, Neuenschwander B, Perrelet R, Lippuner K.(PubMed)

(413) Water solution of onion crude powder inhibits RANKL-induced osteoclastogenesis through ERK, p38 and NF-kappaB pathways by Tang CH1, Huang TH, Chang CS, Fu WM, Yang RS.(PubMed)

Most Common Diseases of elder: The Clinical Trials and Studies of Musculo-Skeletal disorders: Osteoporosis Treatment : Life style modification herbal and traditional Chinese medicine perspective

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                Osteoporosis

Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and often associated with senescence in vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(6).

                               The Treatment

B. In herbal  and traditional Chinese medicine perspective
B.1. Life style modification according herbal and TCM medicine specialist
Life style modification has shown to be beneficiary for patients with osteoarthritis, osteoporosis and rheumatoid arthritis to improve musculoskeletal and bone health and reduce disability, according to the University of Tasmania(383). Modern herbal and TCM medicine specialists may suggest the following
1. Maintain proper weight
Lean women and women with abnormal weight change are found to associate the risk factors and risk of proximal femur bone loss(384).
According to the joint study lead by the David Geffen School of Medicine at University of California, Los Angeles, Postmenopausal weight change such as weight gain, weight loss, and intentional weight loss are associated with increased incidence of fracture, including upper limbs, lower limbs, and central body; hip fracture,...(385). 

2. Physical activity
Exercise, today is less popular leisure-time activity in many countries throughout the Western world, especially in the youth due to promotion of information collection through mobile phone. According to study, moderate exercise, has found to prevent and ameliorated the risk of osteoporosis(389). A physically active women has found to associate to reduce risk of osteoporosis (384) in compared with physically inactive women(386). According to the Federal University of São Paulo, physical exercise is an important stimulus for osteoporosis, as it improves bone microarchitecture, bone density and bone strength, as well as increasing physical function(387), through the stimulation of bone tissue, muscle strength and muscle contraction(387).

6-month whole body vibration training, in older women reduced risk factors for falls and fractures, the Faculteit Lichamelijke Opvoeding en Kinesitherapie suggested(388).

Exercise training showed to  reduce bone turnover, improve hip bonemineral density despite decline in bone-active hormones in in obese hormone decreased aging adults(390).

3. Stop smoking

Smoking, a behavioral risk factor has long been known for its negative effects on over health, causing 3.3 billions pounds of unnecessary burden to the health care system on UK alone(428).

The 2003/2004 South African Demographic and Health Survey, suggested that smoking is positively associated with osteoporosis and lifetime use of both snuff and cigarettes may increase risk osteoporosis among women who are 40 years and older(429). DR. Kim KH, and the research team at the Seoul National University College of Medicine in the study of second hand smoke said " postmenopausal never-smoking Korean women, exposure to SHS was positively associated with osteoporosis". Postmenopausal Women who are exposured to SMS are found to associate to increased occurrences for lumbar and femoral neck osteoporosis if hercohabitant smokers consumed ≥20 cigarettes/day(430). 

In fact, the researchers at the Catholic University of Korea in the study of smoking relationship between smoking and bone mineral density (BMD) showed that urinary continence level is directly related to the BMD at femur neck, total femur, and lumbar spine among postmenopausal females in dose depend-manner(431).

4. Alcoholism
Moderate alcohol drinking has long been associated to over all health and longevity. In dose depent-manner, alcohol intake among menopausal women are highly significant correlated with osteoporosis, causing the quantity and quality of BMD declines gradually or even rapidly(432). A radiographic survey of 96 fully ambulatory male patient with chronic alcoholism between age ranged from 24 to 62 year showed that osteoporosis is found in most of the patient regardless of age. Bone loss has also found in patient relatively young from age 31 to 45 years(427).
The joint study lead by State University of Sao Paulo also insisted that chronic alcoholism may affect bones in general through induced apoptosis of osteoblasts and osteocytes and bone cells(433).

Arthritis Is Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)

(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)

(3) Osteoporosis(Life extension)

(4) Hormone and bone by Francisco Bandeira1, Marise Lazaretti-Castro2, John P. Bilezikian3

(5) Growth hormone and bone by Ohlsson C1, Bengtsson BA, Isaksson OG, Andreassen TT, Slootweg MC.(PubMed)

(6) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)

(383) Lifestyle modifications to improve musculoskeletal and bone health and reduce disability--a life-course approach by Jones G1, Winzenberg TM2, Callisaya ML3, Laslett LL4.(PubMed)

(384) Bone loss, physical activity, and weight change in elderly women: the Dubbo Osteoporosis Epidemiology Study by Nguyen TV1, Sambrook PN, Eisman JA.(PubMed)

(385) Postmenopausal weight change and incidence of fracture: post hoc findings from Women's Health Initiative Observational Study and Clinical Trials by Crandall CJ1, Yildiz VO2, Wactawski-Wende J3, Johnson KC4, Chen Z5, Going SB6, Wright NC7, Cauley JA8.(PubMed)

(386) Independent predictors of all osteoporosis-related fractures among healthy Saudi postmenopausal women: the CEOR Study by Rouzi AA1, Al-Sibiani SA, Al-Senani NS, Radaddi RM, Ardawi MS.(PubMed)

(387) Physical exercise and osteoporosis: effects of different types of exercises on bone and physical function ofpostmenopausal women by Moreira LD1, Oliveira ML1, Lirani-Galvão AP1, Marin-Mio RV1, Santos RN1, Lazaretti-Castro M1.(PubMed)

(388) Effect of 6-month whole body vibration training on hip density, muscle strength, and postural control inpostmenopausal women: a randomized controlled pilot study by Verschueren SM1, Roelants M, Delecluse C, Swinnen S, Vanderschueren D, Boonen S.(PubMed)

(389) Physical activity in the prevention and amelioration of osteoporosis in women : interaction of mechanical, hormonal and dietary factors by Borer KT1.(PubMed)

(390) Exercise training in obese older adults prevents increase in bone turnover and attenuates decrease in hip bonemineral density induced by weight loss despite decline in bone-active hormones by Shah K1, Armamento-Villareal R, Parimi N, Chode S, Sinacore DR, Hilton TN, Napoli N, Qualls C, Villareal DT.(PubMed)

(391) Osteoporosis and inflammation by Mundy GR1.(PubMed)

(392) An association between abnormal bone turnover, systemic inflammation, and osteoporosis in patients with chronic pancreatitis: a case-matched study by Duggan SN1, Purcell C1, Kilbane M2, O'Keane M2, McKenna M2, Gaffney P3, Ridgway PF1, Boran G3, Conlon KC4.(PubMed)

(393) [Regulation of bone metabolism in osteoporosis : Novel drugs for osteoporosis in development].[Article in German]by Jakob F1, Genest F2, Baron G2, Stumpf U3, Rudert M2, Seefried L2.(PubMed)

(394) The effect of garlic tablet on pro-inflammatory cytokines in postmenopausal osteoporotic women: a randomized controlled clinical trial by Mozaffari-Khosravi H1, Hesabgar HA, Owlia MB, Hadinedoushan H, Barzegar K, Fllahzadeh MH.(PubMed)

(395) Role of peritoneal macrophages and lymphocytes in the development of hypogonadal osteoporosis in an ovariectomized rat model: possible phytoestrogenic efficacy of oil extract of garlic to preserve skeletal health by Mukherjee M1, Das AS, Das D, Mukherjee S, Mitra S, Mitra C.(PubMed)

(396) Role of oil extract of garlic (Allium sativum Linn.) on intestinal transference of calcium and its possible correlation with preservation of skeletal health in an ovariectomized rat model of osteoporosis by Mukherjee M1, Das AS, Das D, Mukherjee S, Mitra S, Mitra C.(PubMed)

(397) Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison with the effects of lovastatin and 17beta-estradiol by Mukherjee M1, Das AS, Das D, Mukherjee S, Mitra S, Mitra C.(PubMed)

(398) Prevention of bone loss by oil extract of garlic (Allium sativum Linn.) in an ovariectomized rat model ofosteoporosis by Mukherjee M1, Das AS, Mitra S, Mitra C.(PubMed)

(399) Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa) by Chainani-Wu N1.(PubMed)

(400) Antioxidant and anti-inflammatory properties of curcumin by Menon VP1, Sudheer AR.(PubMed)

(401) A diarylheptanoid phytoestrogen from Curcuma comosa, 1,7-diphenyl-4,6-heptadien-3-ol, accelerates human osteoblast proliferation and differentiation by Tantikanlayaporn D1, Robinson LJ, Suksamrarn A, Piyachaturawat P, Blair HC.(PubMed)

(402) Bone sparing effect of a novel phytoestrogen diarylheptanoid from Curcuma comosa Roxb. in ovariectomized rats by Tantikanlayaporn D1, Wichit P, Weerachayaphorn J, Chairoungdua A, Chuncharunee A, Suksamrarn A, Piyachaturawat P.(PubMed)

(403) Curcumin: getting back to the roots by Shishodia S1, Sethi G, Aggarwal BB.(PubMed)

(404) The acute effects of green tea and carbohydrate coingestion on systemic inflammation and oxidative stress during sprint cycling by Suzuki K1, Takahashi M1, Li CY2, Lin SP3, Tomari M1, Shing CM4, Fang SH5.(PubMed)

(405) Green tea polyphenols change the profile of inflammatory cytokine release from lymphocytes of obese and lean rats and protect against oxidative damage by Molina N1, Bolin AP1, Otton R2.(PubMed)

(406) Green tea supplementation benefits body composition and improves bone properties in obese female rats fed with high-fat diet and caloric restricted diet by Shen CL1, Han J2, Wang S3, Chung E4, Chyu MC5, Cao JJ6(PubMed)

(407) Epigallocatechin-3-gallate (EGCG) as a pro-osteogenic agent to enhance osteogenic differentiation of mesenchymal stem cells from human bone marrow: an in vitro study by Jin P1, Wu H, Xu G, Zheng L, Zhao J.(PubMed)

(408) Dietary patterns and osteoporosis risk in postmenopausal korean women by Park SJ1, Joo SE, Min H, Park JK, Kim Y, Kim SS, Ahn Y.(PubMed)

(409) A natural formulation (imoviral™) increases macrophage resistance to LPS-induced oxidative and inflammatorystress in vitro by Menghini L1, Leporini L1, Pintore G2, Ferrante C1, Recinella L1, Orlando G1, Vacca M1, Brunetti L1.(PubMed)

(410) Dietary calcium and vitamin D2 supplementation with enhanced Lentinula edodes improves osteoporosis-like symptoms and induces duodenal and renal active calcium transport gene expression in mice by Lee GS1, Byun HS, Yoon KH, Lee JS, Choi KC, Jeung EB.(PubMed)

(411) The association between onion consumption and bone density in perimenopausal and postmenopausal non-Hispanic white women 50 years and older by Matheson EM1, Mainous AG 3rd, Carnemolla MA.(PubMed)

(412) [Osteoporosis diet].[Article in German] by Morselli B1, Neuenschwander B, Perrelet R, Lippuner K.(PubMed)

(413) Water solution of onion crude powder inhibits RANKL-induced osteoclastogenesis through ERK, p38 and NF-kappaB pathways by Tang CH1, Huang TH, Chang CS, Fu WM, Yang RS.(PubMed)

(360)

(416) Salmon calcitonin (Miacalcic) nasal spray in prevention and treatment of osteoporosis by Gennari C1.(PubMed)

(417) A randomized trial of nasal spray salmon calcitonin in men with idiopathic osteoporosis: effects on bone mineral density and bone markers by Trovas GP1, Lyritis GP, Galanos A, Raptou P, Constantelou E.(PubMed)

(418) Effects of salmon calcitonin treatment on serum and synovial fluid bone formation and resorption markers inosteoporosis patients by Atbinici H1, Sipahioğlu S2, Aksoy N3, Baykara İ2, Işıkan UE2.(PubMed)

(419) Salmon calcitonin in the treatment of elderly women with type 2 diabetes complicated with osteoporosis by Dexue L1, Yueyue Z2.(PubMed)

(420) Efficacy and safety of oral recombinant calcitonin tablets in postmenopausal women with low bone mass and increased fracture risk: a randomized, placebo-controlled trial by Binkley N1, Bone H, Gilligan JP, Krause DS.(PubMed)

(421) A systematic review of omega-3 fatty acids and osteoporosis by Tonya S. Orchard,1 Xueliang Pan,2 Fern Cheek,3 Steven W. Ing,4 and Rebecca D. Jackson4(PMC)

(422) SCD1 mediates the influence of exogenous saturated and monounsaturated fatty acids in adipocytes: Effects on cellular stress, inflammatory markers and fatty acid elongation by Ralston JC1, Metherel AH2, Stark KD3, Mutch DM4.(PubMed)

(423) Levels of bioactive lipids in cooking oils: olive oil is the richest source of oleoyl serine by Bradshaw HB, Leishman E.(PubMed)

(424) Stereological study of the effect of black olive hydroalcoholic extract on osteoporosis in vertebra and tibia in ovariectomized rats by Noorafshan A1, Dabbaghmanesh MH, Tanideh N, Koohpeyma F, Rasooli R, Hajihoseini M, Bakhshayeshkaram M, Hosseinabadi OK.(PubMed)

(425) Olive oil effectively mitigates ovariectomy-induced osteoporosis in rats by Saleh NK1, Saleh HA.(PubMed)

(426) Olive oil in the prevention and treatment of osteoporosis after artificial menopause by Liu H1, Huang H1, Li B1, Wu D1, Wang F1, Zheng Xh1, Chen Q1, Wu B1, Fan X1.(PubMed)

(427) Chronic alcoholism. Frequently overlooked cause of osteoporosis in men by Spencer H, Rubio N, Rubio E, Indreika M, Seitam A.(PubMed)

(428) The economic burden of ill health due to diet, physical inactivity, smoking, alcohol and obesity in the UK: an update to 2006-07 NHS costs by Scarborough P1, Bhatnagar P, Wickramasinghe KK, Allender S, Foster C, Rayner M.(PubMed)

(429) Epidemiological association between osteoporosis and combined smoking and use of snuff among South African women by Ayo-Yusuf OA1, Olutola BG.(PubMed)

(430) Secondhand smoke exposure and osteoporosis in never-smoking postmenopausal women: the Fourth Korea National Health and Nutrition Examination Survey by Kim KH1, Lee CM, Park SM, Cho B, Chang Y, Park SG, Lee K.(PubMed)

(431) Dose-related effect of urinary cotinine levels on bone mineral density among Korean females by Myong JP1, Kim HR, Choi SE, Koo JW.(PubMed)

(432) Prevalence and risk factors associated with osteoporosis in women attending menopause clinic at Hat Yai Regional Hospital by Jarupanich T1.(PubMed)
(433) Alcoholic and isocaloric diet, but not ovariectomy, influence the apoptosis of bone cells within the alveolar bone crest of rats by Marchini AM1, Gonçalves LL2, Salgado MC1, do Prado RF1, Marchini L3, Carvalho YR1, da Rocha RF1.(PubMed)