Wednesday, 7 June 2023

#Healthyfood #RedCabbage #HydroalcoholicExtract Improves Sleep Quality in Elderly, Researchers Show

By Kyle J. Norton

Most of us experience sleep disturbance sometimes. However, chronic sleep disorders are the changes in the way that you sleep.
Sleep disorders can be acute or chronic. Acute sleep disorder caused by specific or nonspecific events can resolve quickly in short times after the event is addressed.

Ignoring sleep disorders have been found to induce poor health, poor mood, and lethargy, and sometimes have a negative impact on motivation, relationships, and job performance in daily life.

Some people who use over the counter medicine or herbal medicine without consulting the experts may experience side effects and in some cases, worsening sleep problems.

Most people with chronic sleep disorder experience symptoms of excessive daytime sleepiness, irregular breathing or increased movement during sleep, and difficulty falling asleep.

Sleep quality can be measured by examing the.way that you sleep, including the time period that you need to fall to sleep and how many times you have awakened and drifted back to sleep during night sleep.

The National Sleep Foundation’s inaugural Sleep Health Index showed, 45 % of Americans have poor or insufficient sleep that affects their daily activities at least once in the past seven days.

Depending on the types of sleep disorder, the most common causes of chronic sleep disorder are caffeine consumption, lack of regular exercise, poor stress management and the increase in aging.

Dr. Keisuke Suzuki, the lead scientist at the Dokkyo Medical University in the investigation of sleep disorders in the elderly wrote, "Compared with younger people, elderly people show age‐related sleep changes, including an advanced sleep phase and decreased slow‐wave sleep, which results in fragmented sleep and early awakening".

And, "Multiple etiologies contribute to insomnia in the elderly, consistent with the observation that elderly people are likely to have comorbid conditions and medications".

Red cabbage is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.

In finding the potent compound for the improvement of sleep quality, researchers investigated the effect of the hydroalcoholic extract of red cabbage and its fractions on sleeping behavior in mice.

According to the tested analysis, the extract increased sleep duration at doses of 50–200mg/kg (P < 0.001), comparable to that of diazepam (3mg/kg) and those of the control group.

The extract decreased sleep latency was attributed to the ethyl acetate fraction LD50 value in the red cabbage extract of 2.4g/kg.

Most importantly, no toxic effect on the viability of cultured neuronal cells (PC12) was found in the tested hydroalcoholic extract.

Collectively, researchers said, "Red cabbage potentiates pentobarbital hypnosis without any toxic effect. The main component(s) responsible for this effect is most likely to be an intermediate polar agent(s) such as flavonoids, which are found in the ethyl acetate fraction of this plant".

Taken altogether, red cabbage may be considered a functional food for the promotion of sleep quality, pending the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Hypnotic Effect of Red Cabbage (Brassica oleracea) on Pentobarbital-Induced Sleep in Mice by Azar Hosseini, Mohammad-Ali Sobhanifar,1 Fatemeh Forouzanfar,1 Azita Aghaee, and Hassan Rakhshandeh. (PMC)
(2) Sleep disorders in the elderly: Diagnosis and management by Keisuke Suzuki, MD, Ph.D. Masayuki Miyamoto, MD, Ph.D., and Koichi Hirata, MD, Ph.D. (PMC)

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