Friday 9 June 2023

#Healthyfood #Asparagus Exhibits Anti-#LiverCancer, in Vitros and Vivos, According to Scientists

By Kyle J. Norton

Asparagus is a flowering plant belonging to species of the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, northwest Germany, northern Africa, and western Asia. Asparagus has been used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties. 

Cancer is a class of diseases in which a group of cells growing and multiplying in disordered and uncontrollable ways in our body, have become progressively worse and damage other healthy tissues, sometimes spreading to other organs in the body via lymph or blood and results may be in death.

Liver Cancer is defined as a condition of the abnormal proliferation of cells in the liver.

Its chemical constituents include essential oils, asparagine, arginine, tyrosine, flavonoids (kaempferol, quercetin, and rutin), resin, and tannin.

Asparagus may be one of the potential herbs used in the future to treat liver cancers as its chemical constituents exert their anti-cancer properties in many studies.

Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies in the world, but deproteinized asparagus polysaccharide exerts potent selective cytotoxicity against hepatocellular carcinoma Hep3B and HepG2 cells. in vitro and in vivo, according to the researcher's team led by Dr. Xiang J. Others in the analysis of Shatavari IV isolated from ethyl acetate insoluble fraction (AR-2B) of chloroform: methanol (2:1) (AR-2) extract of A. racemosus roots, indicated that Shatavari exhibits significant anticancer activity in both in vitro and in vivo experimental models. 

In fact, intakes of celery, mushrooms, allium vegetables, composite vegetables (including asparagus lettuce and garland chrysanthemum), legumes, and legume products were widely known to associate with reduced liver cancer risk.

Reference
(1) Chemical constituents of Asparagus J. S. Negi, P. Singh, [...], and V. K. Bisht (PubMed)
(2) Anticancer effects of deproteinized asparagus polysaccharide on hepatocellular carcinoma in vitro and in vivo. by Xiang J, Xiang Y, Lin S, Xin D, Liu X, Weng L, Chen T, Zhang M.(PubMed)
(3) Shatavarins (containing Shatavarin IV) with anticancer activity from the roots of Asparagus racemosus. by Mitra SK, Prakash NS, Sundaram R.(PubMed)
(4) Vegetable-based dietary pattern and liver cancer risk: results from the Shanghai women's and men's health studies. by Zhang W, Xiang YB, Li HL, Yang G, Cai H, Ji BT, Gao YT, Zheng W, Shu XO.(PubMed)

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