Peyronie's disease is a rare condition caused by plaque, that forms inside the penis, leading to a bent erect penis, depending on where the plaque is located.
Patients with Peyronie's disease have been found to affect sexual desire due to a physical condition associated with painful sexual intercourse and erectile dysfunction.
Researchers do not know the exact causes of Peyronie's disease. However, according to epidemiological studies, researchers suggested that injury that causes bleeding inside the penis may induce the build-up of scars, particularly in men with the genetic preposition of certain genes.
Most cases of pain in Peyronie’s disease are mild and often do not require treatment, however, over counter medicine may be needed occasionally.
Believe it or not, most mild cases of men with Peyronie's disease do not require treatment as the condition has been found to go away within a year. In severe cases, surgery may be necessary to remove the scar tissues in the penis that cause the condition.
Bilberry is a species of low-growing shrub in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as an herb in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
Researchers on finding a natural compound for the treatment of Peyronie's disease investigated various antioxidants, including bilberry in PD treatment with a significant increase in the likelihood of therapeutic success.
By comparing the effects of silymarin, ginkgo biloba, vitamin E, bilberry, topical diclofenac sodium, and pentoxifylline (PTX) in patients with PD, researchers found that by administration of a single oral antioxidant; two oral antioxidants; three oral antioxidants; five oral antioxidants + local diclofenac; and five oral antioxidants + local diclofenac + PTX achieve better results when combining more than one agent.
According to the tested assays, the combination of more than a single compound reduced the symptoms in patients with PD, including the improvement and disappearance of penile pain; percentage of reduction in the volume of penile plaque; reduction in penile curvature; recovery of erectile function in patients with erectile dysfunction; increase in the International Index of Erectile Function score; and reduction of psychosexual impact.
Particularly, treatment of combined therapy including oral treatment with more than one antioxidant is greater when topical use of diclofenac gel and perilesional injection of PTX, compared to those of single conventional medicine.
In other words, combining natural or dietary antioxidants such as bilberry into the diet of patients with PD is more effective in inhibiting the symptoms compared to the use alone of any single ingredient therapy.
The final outcome of 6 months of treatment showed that combined antioxidant therapy is effective in treating PD.
Dr. Paulis G, the lead scientist, after taking other factors into account wrote in the final report, " Although several articles have already been published reporting the effectiveness of combined treatment in PD, this is the first study clearly proving how, as the number of substances used in treatment rises, a proportionally greater therapeutic effect is achieved."
Taken altogether, bilberry combined with other antioxidants or conventional medicines may be considered function remedies for the treatment of Peyronie's disease (PD), pending the validation of a larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Rationale of combination therapy with antioxidants in the medical management of Peyronie's disease: results of clinical application by Paulis G1,2, Paulis A3, Romano G4, Barletta D5, Fabiani A. (PubMed)
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