Tuesday 23 April 2019

Whole Food Ginger Enhances the Chance of Conception in Vivo

By Kyle J. Norton

Fertility is a natural process to ensure the survival of human species. Through natural selection, we produce many offsprings when the reproductive system works at its peak in a suitable environment.

In other words, female fertility is the ability of women to conceive a biological child before menopause compared to male fertility which generally relies on the quantity and quality of the sperms.

But regardless of all factors, most women are capable of conceiving during their menstrual cycle before reaching the stage of menopause.

Infertility is a condition characterized by the inability of a couple to conceive after 12 months of unprotected sexual intercourse or can not carry the pregnancy to term.

The condition affects over 5 million couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from a professional specialist.

Epidemiologically, the rate of pregnancy statistics shows that before:

* The age of 31, 73% of women will get pregnant within one year, and 90% within four years.

* The age of 36, 65% of women will get pregnant within one year, and 82% within four years.

* The age of 41, 40% of women will get pregnant within one year, and 60% within four years.

You can see the rate of pregnancy goes down with age.

Although women can get pregnant anytime during their menstrual cycle, the best days to get pregnant are 2 days before and after ovulation because the sperm can only survive 2-3 days(sperm may survive up to 6 days) in the uterus after ejaculating into the vagina.

In the Western world, most cases of infertility are associated with no explanation.

Unexplained causes of infertility may be the reasons which drive many couples to seek help from alternative medicine.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Researchers on finding a natural ingredient for the treatment of female infertility examined the effects of ginger powder on ovarian folliculogenesis and implantation in an animal model.

Selected rats for the study were divided into 2 groups. 7 rats included in each in 5 days (one estrous cycle) treatment was given 100 mg ginger powder, 200 mg ginger powder and or distilled water respectively.

In the 10 days treatment group, same doses were given for 10 days (two estrous cycles) to the three subgroups each also containing seven rats.

According to results from the tested assay at the end of the 5th day, the 5-day treatment group with 100 mg ginger subgroup exerted a significantly higher antral follicle count and ovarian stromal VEGF, an indication of increased blood in the ovaries, compared to other subgroups.

Observation at the end of the 10th days, the 10 days treatment groups with 100 mg ginger showed a significantly higher endometrial VEGF and ovarian stromal eNOS, compared to the other groups.

In other words, ginger at doses of 100mg improved the function of ovaries secretion of mature follicles and endometrial function in facilitating conception by increasing blood flow to the reproductive organs.

Interestingly, at 200 mg ginger dose produced no statistically significant difference in both 5-day and 10-day treatment groups.

The finding strongly suggested that ginger improved female fertility in doses dependent manner. The optimized doses to induce fertility are 100mg.

Researchers in the final report wrote, "The increases in the antral follicle count and ovarian stromal VEGF in the 100 mg/5-day treatment subgroup indicate that ginger has positive effects on folliculogenesis in short term with a low dose. Additionally, ginger may enhance implantation in rats in the long term with low dose".

Taken altogether, ginger may be considered a functional remedy for the improvement of female fertility, pending to the confirmation of larger sample sized and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Ginger (zingiber officinale) might improve female fertility: A rat model by Nafiye Banu SevenaHakan,Timura Ayçağ,Yorgancıa Hasan, Ali İnalb Müberra, Namlı,Kalemc, Ziya Kalemd, ÖzgeHane, Banu Bilezikçie (Science Direct)

Manuka Honey improves the Cellular Antioxidant Defense Enzymes

By Kyle J. Norton

On seeking natural therapy with no side effects, scientists may have a herbal remedy for the treatment of diseases associated with oxidative stress, according to studies.

Free radical or reactive oxygen species are unstable atoms with unpaired electrons on the outermost ring that are ready to donate or intercept an electron from other atoms, leading to a chain reaction which can not be stopped until they all electrons on the outermost ring are paired or inhibited by antioxidants.

On the other hand, antioxidants are stable atoms which inhibit oxidation caused by free radicals.

In healthy individuals, antioxidant enzymes produced by the liver are good enough to balance the free radical produced by the cell metabolism and external sources such as the air we breathe and the food we eat.

However, in people with a weakened immune system such as infants, children and the elderly, dietary sources from supplements, fruits and vegetables may be needed.

Oxidative stress is a result of an imbalance of the ration of free radical and antioxidant in the body. A prolonged period of oxidative stress has been found to cause proteins and lipid damage and alteration of cell DNA inducing chronic diseases such as CVD, diabetes, and cancer.

Believe it or not, free radicals also play a critical role in maintaining a certain body function. The Journal of Physiology showed that free radicals act as signal substances that cause the heart to beat with the correct force.

In other words, Dr. says Håkan Westerblad said, ""Free radicals play an important role since they contribute to the heart being able to pump more blood in stress-filled situations."

And "On the other hand, persistent stress can lead to heart failure, and chronically increased levels of free radicals may be part of the problem here."

Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers.

The liquid is considered one of the healthy food for replacing the use of white sugar and artificial sweetener by many people.

With an aim to find a natural ingredient which enhances the cellular antioxidant defense system against diseases, researchers examined Manuka honey effects in the genotoxic and genoprotective properties in cells activity against free radicals in the ranging from 25-1000 μg/mL.

In a modest decrease of H2O2-induced cellular DNA damage, Manuka honey displayed a stronger potential to attenuate damaged cells at all tested concentrations, particularly in the concentrations of 25 and 100 μg/mL.

More precisely, Manuka honey protected DNA of whole blood cells from oxidative damage induced by hydrogen peroxide in vitro.

Furthermore, Manuka honey exerted a similar activity against free radical overexpression, compared to buckwheat honey which has higher contents of sugars, proteins, and total phenols but a lower content of MGO.

Additionally, Manuka honey also exhibited a strong cellular antioxidant and antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa,, compared to those of buckwheat honey.

Where buckwheat honey is considered to have great nutritional and commercial potentials

Taken altogether, Manuka honey may be considered anti hypertension functional remedy for the enhancement of the cellular antioxidant defense system with no side effects, pending to the confirmation of large sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Biochemical properties, antibacterial and cellular antioxidant activities of buckwheat honey in comparison to manuka honey by Deng J1, Liu R2, Lu Q3, Hao P1, Xu A1, Zhang J2, Tan J. (PubMed)
(2) Manuka honey attenuates oxidative damage induced by H2O2 in human whole blood in vitro by Živković L1, Bajić V2, Dekanski D3, Čabarkapa-Pirković A4, Giampieri F5, Gasparrini M5, Mazzoni L6, Potparević BS. (PubMed)
(3)  Mitochondrial production of reactive oxygen species contributes to the beta-adrenergic stimulation of mouse cardiomycytes. by Daniel C Andersson, Jérémy Fauconnier, Takashi Yamada, Alain Lacampagne, Shi-Jin Zhang, Abram Katz & Håkan Westerblad (The Journal of Physiology)

Turmeric Protects Your Skin Against Photo-Damage

By Kyle J. Norton

Photodamage is a type of skin damage caused by long-term exposure to the sunlight or tanning bed.

Photodamage skin is one most common form of skin damage in the US, due to misunderstanding the benefits and adverse effects on light exposure.

Believe it or not, a quarter of lifetime sun exposure occurs before the end of the teenage years. Most cases of photo skin damage can also stimulate some unwanted skin conditions, including advanced aging or wrinkling, uneven skin, hyperpigmentation, telangiectasias, actinic keratoses liver, and age spots.

In severe cases, long-term photodamage skin can also lead to skin cancer. More people in the US are diagnosed with skin cancer each year than all other cancers combined.

According to the statistic, 1 in 5 Americans will develop skin cancer by the age of 70.

Conventionally, most cases of early-stage and mild damage of skin are treated by topical Levulan that remove scaly patches of actinic keratoses from your skin.

However, Laser surgery may be necessary, if the topical fails.

Dr. Jee SH, the lead scientist in the examination of the risk of photodamage skin in the risk of skin cancer wrote, "Some workers in paraquat manufacturing, exposed to bipyridines, have developed pigmentation and keratosis on sun-exposed skin".

And, "This pathologic study proves that all the lesions showed either photodamage or skin cancer. The strong trend in the correlation between the severity of photodamage and exposure to bipyridine leads to the speculation about the synergistic role of bipyridine exposure and the solar effect in causing these malignant and premalignant skin lesions".

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

In the concerns of Ultraviolet B (UVB) irradiation in inducing skin photo-damage associated with the onset of a sunburn, erythema, photoaging, and photocarcinogenesis, researchers evaluated the protective effects of curcumin against acute photo-damage.

In hairless mice, topical application of curcumin exerted a kin protective effect by significantly inhibiting acute UVB (540 mJ cm-2 , for 3 successive days)-induced inflammatory cells, collagen accrementition derangement, and lipid peroxidation.

Additionally, the topical cream with curcumin also stimulated the NF-E2-related factor 2 (Nrf2) nuclear accumulation involved in skin defense on uncovered (Uncv) hairless mice skin.

In vitro, treatment of HaCaT cells with curcumin significantly attenuated acute UVB (300 mJ cm-2 ) tissue damage in releasing lactate dehydrogenase release (LDH) into the bloodstream.


Levels of intracellular reactive oxygen species production and DNA damage are also inhibited by the injection of curcumin by activating the expression of phase II detoxifying enzymes and promoting DNA repair activity. 

Additional analysis of the skin protective activity of curcumin, researchers found that The photoprotective effect provided by curcumin was potentially associated with modulation of Nrf2-factor associated with antioxidant defense.

In order to reveal more information about the effects of turmeric anti skin damage, researchers looked into the turmeric and turmeric-containing polyherbal combination tablets versus placebo on facial redness.

The prospective, double-blind, randomized pilot study included 33 healthy participants were recruited from the dermatology clinic at the University of California, Davis and nearby community from 2016 to 2017 receive one of three interventions (placebo, turmeric or polyherbal combination tablets) and were told to take the intervention tablets by mouth twice daily for 4 weeks.

According to the results, the polyherbal combination group had a significant decrease in redness of 40% compared to baseline (P = 0.03) compared to that of placebo and turmeric groups with no statistically significant changes in image analysis-based facial redness.

Based on the findings, researchers said, "Polyherbal combination tablet supplementation improved facial redness compared to the turmeric or placebo".

Taken altogether, turmeric processed a high amount of bioactive compound curcumin used alone or combined with other phytochemical may be used for the prevention of skin photo-damage, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective Effect of Curcumin Against Acute Ultraviolet B Irradiation-induced Photo-damage by Li H1, Gao A1, Jiang N1, Liu Q1, Liang B1, Li R1, Zhang E1, Li Z1, Zhu H. (PubMed)
(2) Dietary supplementation with turmeric polyherbal formulation decreases facial redness: a randomized double-blind controlled pilot study by Vaughn AR1, Pourang A2, Clark AK2, Burney W2, Sivamani RK. (PubMed)
(3) Photodamage and skin cancer among paraquat workers by Jee SH1, Kuo HW, Su WP, Chang CH, Sun CC, Wang JD. (PubMed)

Monday 22 April 2019

Contrast to General Belief, Bilberry Can Not Improve Night Vision in Healthy Individuals

By Kyle J. Norton


Vision is a process of detecting light patterns from the outside world and projecting them into images that allow us to see.

Reduced vision is the partial loss of vision, either temporary or permanent. 

Night vision is the ability to see in low-light conditions, particularly at the night time

There are some risk factors associated with a reduced night vision, including vitamin A deficiency, people with cataracts, a condition of clouding of the lens in the eye, people with diabetes and eye surgery complications.

Some researchers suggested that people with certain gene inherited from the parent may have better night vision compared to those without.

According to the Scripps Research Institute in the examination of how a particular gene makes night vision possible, published in the August 10, 2011 edition of The Journal of Neuroscience, nyctalopin coordinates the assembly and precise delivery to the synapse of the macromolecular complex consisting of mGluR6, a neurotransmitter receptor protein, which directly communicates with rod photoreceptors and TRPM1, a protein channel that generates the response, making vision possible.

These may be the reason that some people can see better than others in a low light condition


Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.


The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.

Searching the list of natural compounds for the treatment of poor night vision, researchers reviewed placebo-controlled trials of V. myrtillus-extracted anthocyanosides for evidence of positive effects on night vision.

According to the standard guidelines and criteria, 30 trials with outcome measures relevant to vision in reduced light were selected for the review.

According to healthy subjects with normal or above average eyesight tested in 11 of the 12 trials, injection of V. myrtillus anthocyanosides improves normal night vision.

However, due to the lack of rigorous research into the effects of the extract on subjects suffering impaired night vision due to pathological eye conditions, researchers suggested that further trials of V. myrtillus anthocyanosides in subjects with impaired night vision.

In a study included 6 young normal volunteers randomly assigned to one of four different regimens of single oral administrations of 12, 24 and 36 mg of anthocyanosides, and a placebo, with a 2 week washout period between doses.

According to the 3-night vision tests: full-field scotopic retinal threshold (SRT), dark adaptation rate (DAR) and mesopic contrast sensitivity (MCS) conducted by the Assaf Harofeh Medical Center, a single oral administration of 12, 24 or 36 mg anthocyanosides after 24 hours.

These results that single oral administration of 12-36 mg of anthocyanosides does not have a significant effect on militarily relevant night vision tests.

Taken altogether, bilberry although showed a significant improvement of the eyesights caused by visual degeneration and diabetic complication, however, it can not improve night vision in healthy individuals.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision--a systematic review of placebo-controlled trials by Canter PH1, Ernst E. (PubMed)
(2) The effect of anthocyanosides on night vision by Levy Y1, Glovinsky Y. (PubMed)
(3) How a particular gene makes night vision possible by Scripps Research Institute. (Science Daily)

Whole Food Ginger, the Best for the Treatment of Gastroesophageal Reflux Disease (GERD)

By Kyle J. Norton

Scientists may have found a natural ingredient for the treatment of gastroesophageal reflux disease, with no side effects, according to study.

Gastroesophageal reflux disease (GERD) is a digestive disorder caused by the relaxation of the low end of the esophageal sphincter muscle which connects with the stomach at the wrong times, leading to return of the stomach's contents back up into the esophagus.

Under normal digestion, the lower esophageal sphincter (LES) closed after opening to allow food to pass into the stomach.

People with GERD may have symptoms of heartburn, a burning sensation in your chest usually after eating, chest pain, regurgitation of food or acid liquid.

In serious cases, patients may experience symptoms of difficulty swallowing.

Most cases of GERD symptoms can be managed by lifestyle changes and over-the-counter medications. However, some people may need surgery to ease symptoms.

Unmanaged GERD has been found to damage the esophageal tissue and dysfunctional valve at the top of the stomach and bottom of the esophagus in some patients.

The exact causes of GERD are unidentified. Being overweight and obesity, intake of certain medications, being a smoker and exposed to second-hand smoke are some factors associated with the prevalent risk of the condition.

Out of many risk factors, some researchers suggested aging may be a common risk of GERD in the elderly.

Dr. David A. Johnson, said, "The prevalence of erosive esophagitis and other complications of gastroesophageal reflux disease increase with age. Additionally, among all people with GERD, older adults are more likely to suffer severe complications, such as Barrett esophagus and esophageal carcinoma, than are younger people".

And, "Older age was associated independently with increasing acid exposure (P<0.0001), decreases in intra-abdominal LES length (P<0.001), increases in esophageal dysmotility, and increasingly ineffective peristalsis".

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

In the urgency to find a natural compound for the treatment of gastroesophageal reflux disease (GERD) and bile reflux gastritis (BRG) which are common gastrointestinal (GI) disorders with unmet medical needs, researchers evaluated the ginger-containing formula Wendan decoction (WDD) targets homeostatic disturbances.

The Wendan decoction (WDD) has been used for thousands of year in traditional Chinese medicine for the treatment of syndromes characterized by "reflux" and "gut-juice exposure" problems.

After reviewing medical data online, 33 studies involved 3253 participants (1351 vs. 1035 of the BRG in 20 publications, 449 vs. 418 of the GERD in 13 studies, and 194 vs. 159 of relapse rate in 6 trials) was selected.

According to the pooled data, application of WDD showed a consistent therapeutic efficacy on BRG (OR = 6.00, 95%C = 4.68-7.69) and GERD (OR = 4.39, 95%CI = 2.72-7.07).

The relapse rate was 12.4% for WDD which significantly lower than 44.0% in the conventional therapies (OR = 0.14, 95%CI = 0.08-0.26).

After taking into account co and confounders, researchers wrote on the final report, "The consistent therapeutic efficacy of the single TCM formula on GERD and BRD indirectly indicates reflux as common pathogenesis in reflux-associated GI disorders".


Take all together, ginger used alone or combined with other herbal medicines may be considered the functional alternatives for the treatment of GERD and BRD, pending to the confirmation of large sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Consistent Efficacy of Wendan Decoction for the Treatment of Digestive Reflux Disorders by Ling W1, Huang Y1,2, Xu JH1,3, Li Y1,4, Huang YM1, Ling HB1,5, Sui Y6, Zhao HL. (PubMed)
(2) GERD and Aging by David A. Johnson, MD reviewing Lee J et al. Clin Gastroenterol Hepatol 2007 Dec. (NEJM Journal Watch)

Herbal Turmeric Protects the Heart Against Cardiac Toxicity

By Kyle J. Norton

Cardiac toxicity is a condition in which the heart has been damage to some extents caused by harmful chemicals, including toxins induced by the treatment of chemotherapy.

Depending on the cells of the areas of the heart  that have been damaged, cardiac toxicity includes

* Cardiomyopathy is a disorder caused a weaken or damage of heart muscle, affecting the heart rhythm or inducing the risk of heart failure.

* Myocarditis is a condition of inflammation of the heart, that can lead to changes in heart rhythm or heart failure.

* Pericarditis is a condition caused by the inflammation of the sac surrounding the heart, inducing chest pain or heart failure.

* Acute coronary syndromes that affect the blood flow due to blood vessel damage.

* Congestive heart failure is a result that affects the function of the heart in pumping blood throughout the body. 

Conventionally, treatment of cardiac toxicity include medication to control fluids, high blood pressure, and medications which improve the hear functioning. If all aforementioned medications fail, a heart transplant may be necessary.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On finding a natural compound for the treatment of cardiac toxicity scientists launched an investigation to determine whether curry intake reduces blood levels of heavy metals, according to the Korean National Health and Nutrition Examination Survey 2013 data.

 1,350 participants selected to the study were randomly divided into either curry intake group with the consumption of a curry dish more than once a month over the previous year, or a non-curry intake group (n = 747).

According to the heavy metal analysis, the curry intake group showed significantly lower heavy metal blood concentrations (Pb, Hg, and Cd).

Furthermore, the levels of heavy metals in patients with hypertension (HTN) were significantly lower in curry intake group compared to the nonhypertension group.

The levels of blood concentrations of heavy metals induced toxicity associated with the induction of hypertension were significantly lower compared to the placebo.

The results confirmed the correlation between blood heavy metal levels and HTN.

In other words, turmeric has a potential effect on reducing cardiac toxicity in the induction of abnormally blood pressure.

In order to obtain turmeric detoxed activity, researchers examined the protective effect of turmeric extract against doxorubicin (DOX)-induced cardiac toxicity in rats. 

According to the tested assays, turmeric extract exerted multiple therapeutic activities that ameliorate the effect of DOX-induced cardiac toxicity.

Additionally, turmeric extract inhibited the DOX-induced increase in plasma cholesterol, LDH, associated with the increased risk of cardiovascular disease.

Dr. Mohamad RH, the lead scientist said, "The present findings conclude that the turmeric extract has multiple therapeutic activities that block the cardiac,.....toxicities".

Taken altogether, turmeric processed a high amount of bioactive compound curcumin may be considered supplements for the prevention of cardiac toxicity, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Reduction in Prevalence of Hypertension and Blood Heavy Metals among Curry-Consumed Korean by Choi JW1, Oh C2, Shim SY1,3, Jeong S4, Kim HS5, Kim MS. (PubMed)
(2)The role of Curcuma longa against doxorubicin (adriamycin)-induced toxicity in rats by Mohamad RH1, El-Bastawesy AM, Zekry ZK, Al-Mehdar HA, Al-Said MG, Aly SS, Sharawy SM, El-Merzabani MM. (PubMed)

Phytochemical Alliin Suppresses the Onset of Hypercholesterolemia

By Kyle J. Norton

Hypercholesterolemia is a chronic condition associated with abnormally high blood cholesterol in the blood

In other words, hypercholesterolemia is a result of overexpression of low-density lipoprotein compared low levels of high-density lipoprotein.

Low-density cholesterol also is known as bad cholesterol produced by the liver or dietary saturated and trans fat in moderate amount plays  a critical role in building a strong cell wall, production of steroid hormones and vitamin D and aiding the gastrointestinal tract in the absorption of nutrients.

However, high levels of bad cholesterol have been found to induce hypercholesterolemia, a leading cause of heart disease and stroke.

High-density lipoprotein or good cholesterol, on the other hand, returns the amount of excess cholesterol back to the liver for future use.

High-density lipoprotein is also produced by the liver and dietary sources found mostly in nut and fish.
The healthy ratio of LDL/HDL is any numbers less than 4.

Although there are many risk factors that cause the onset of hypercholesterolemia, some researchers suggested the introduction of a high-fat diet in North American over the past few decades may accelerate the rise of the condition.

Dr. Cole TG, the lead scientist, in a randomized controlled parallel-designed intervention study to evaluate the effects of a diet with less than 20 g carbohydrates per day (LCHF) on plasma low density lipoprotein cholesterol (LDL-C) in young and healthy adults wrote, "There was a significant increase in apolipoprotein B, total cholesterol, high-density lipoprotein cholesterol, free fatty acids, uric acid and urea in the LCHF group versus controls".


Alliin (S-allyl-L-cysteine-S-oxide) is a phytochemical compound sulfoxide,. a derivative of the amino acid cysteine, belonging to the class of sulfur compounds, found abundantly in fresh garlic and onion.

On finding a natural compound for the treatment of hypercholesterolemia, researchers investigated
the effect of Lichtwer garlic powder (containing 1.3% alliin equivalent to 0.6% allicin) on the serum cholesterol, triglyceride in rats fed with a high cholesterol diet.

Rats selected to the study were randomly dived into experimental rats fed with a 2% high cholesterol diet with and without garlic powder for 6 weeks and control rats fed with normal diet daily.

High cholesterol-fed animals had a significant increase in serum cholesterol compared to the control group of rats fed on a normal diet.

However, in the rat group fed with a high cholesterol diet mixed with garlic powder, researchers found that there was a significant reduction in their serum cholesterol levels compared to other groups.

Lichtwer garlic powder (containing 1.3% alliin equivalent to 0.6% allicin) also lowered the serum triglyceride levels compared to control and high cholesterol diet group rats without affecting the serum glucose and protein.

The finding clearly suggested that Lichtwer garlic powder (containing 1.3% alliin equivalent to 0.6% allicin) is beneficial in reducing blood cholesterol, triglycerides levels in hypercholesterolemic rats.

In order to reveal more information about alliin anti-high blood cholesterol activity, researchers evaluated the capacity of Allium ursinum (wild garlic) leaf lyophilisate (WGLL; alliin content: 0.261%) to mitigate cardiovascular damage in hypercholesterolemic rabbits.

The selected New Zealand rabbits were divided into three groups: (i) cholesterol-free rabbit chow (control); (ii) rabbit chow containing 2% cholesterol (hypercholesterolemic, HC); (iii) rabbit chow containing 2% cholesterol + 2% WGLL (hypercholesterolemic treated, HCT); for eight weeks.

During the study, WGLLtreated group showed a decrease in aortic atherosclerotic plaque coverage, plasma ApoB, a protein in atherogenic lipoprotein particles associated heart disease associated with reduced blood cholesterol.

Furthermore, the activity of LDH and CK (creatine kinase) in plasma is also found to lower compared to other treatment groups.

The plasma LDL was also significantly reduced in WGLL-treated group.

Taken altogether, alliin may be considered supplements for the prevention and treatment of hypercholesterolemia, pending to the confirmation of the larger sample size and multicenter human study.

Intake of alliin in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-Atherogenic Properties of Allium ursinum Liophylisate: Impact on Lipoprotein Homeostasis and Cardiac Biomarkers in Hypercholesterolemic Rabbits by Bombicz M1,2, Priksz D3,4, Varga B5,6, Gesztelyi R7, Kertesz A8, Lengyel P9, Balogh P10, Csupor D11, Hohmann J12, Bhattoa HP13, Haines DD14, Juhasz B. (PubMed)
(2) Effect of garlic on lipid profile and psychopathologic parameters in people with mild to moderate hypercholesterolemia by Peleg A1, Hershcovici T, Lipa R, Anbar R, Redler M, Beigel Y. (PubMed)
(3) Effect of low carbohydrate high fat diet on LDL cholesterol and gene expression in normal-weight, young adults: A randomized controlled study by Retterstøl K1, Svendsen M2, Narverud I3, Holven KB. (PubMed)