Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia due to aging depletion of Kidney Essence - Herbal Du Zhong(Eucommia Bark)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
3. Du Zhong(Eucommia bark)
Du Zhong, the sweet, slightly acrid, and warm, is also known as eucommia bark, used in traditional Chinese medicine as anti stress(1325)(1326), anti diuretic(1336), anti inflammatory(1327)(1328), anti infectious(1329), sedative and anesthesia and anti-aging(1336) agents and to treat hypertension(1330)(1331), chronic pain in lower back and knees(1332)(1336), lack of strength, dizziness, impotence(1337), irregular menses and frequent urination(1336) and protect against unstable pregnancy(1336),.... by enhancing the functions of liver and kidney channels(1333).
Phytochemicals
1. Eucommiol
2. Eucommioside
3. Eucommioside-I
4. Cpmoferom
5. Dehydrodiconife4ryl alcohol-4
6. Gamma'-di-O0betta-D-glucopyranoside
7. Liriodendrin
8. (+) -syringaresinol-di-O-Beta-D-glucopyranoside
9. (+)-syringa resinol O-Beta-D-glucopyranoside
10. (+)-syringaresinol monoglucoside
11. syringin
12. Etc.
1. In learning and memory
In scopolamine-induced learning and memory impairments by a single intracerebroventricular (i.c.v.) injection of Aβ(25-35) mice models, oral administration of aqueous extract of Eucommia bark or the whole herb significantly reversed learning and memory deficits, through inhibition of acetylcholinesterase (AChE)(1335) and thiobarbituric acid reactive substance (TBARS) activities in the hippocampus and frontal cortex in a dose-dependent manner(1334)(1335).
2. In Alzheimer's disease (AD)
In hydrogen peroxide (H(2)O(2))-induced neuronal cell death in human SH-SY5Y neuroblastoma cells, eucommia ulmoides Oliv. Bark. (EUE), increased cell viability and inhibited cytotoxicity and DNA condensation, through attenuated the increase in ROS production and MMP involved increased risk of dementia reduction(1337).
3. In neuroprotective effects
In PC-12 cells injury mediated by Aβ(25-35) eucommia ulmoides Oliv. (EUO)bark and leaf's phytochemicals, geniposidic acid and chlorogenic acid, significantly protected PC-12 cells against the cytotoxicity(1338). In amyloid beta(25-35) (Aβ(25-35))-induced learning and memory impairments mice model, the herb laso exhibited neuroprotective effects through inhibition of acetylcholinesterase (AChE) activity in the hippocampus and frontal cortex(1235).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(1325) Eucommia ulmoides Oliv. bark. attenuates 6-hydroxydopamine-induced neuronal cell death through inhibition of oxidative stress in SH-SY5Y cells by Kwon SH1, Ma SX1, Hong SI1, Kim SY2, Lee SY1, Jang CG3.(PubMed)
(1326) Constituents and pharmacological effects of Eucommia and Siberian ginseng by Deyama T1, Nishibe S, Nakazawa Y.(PubMed)
(1327) Elucidation of anti-inflammatory potencies of Eucommia ulmoides bark and Plantago asiatica seeds by Kim BH1, Park KS, Chang IM.(PubMed)
(1328) Eucommia ulmoides Oliv. bark aqueous extract inhibits osteoarthritis in a rat model of osteoarthritis by Xie GP1, Jiang N2, Wang SN3, Qi RZ4, Wang L5, Zhao PR6, Liang L7, Yu B8.(PubMed)
(1329) Eucommia ulmoides Oliv.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine by He X1, Wang J2, Li M3, Hao D1, Yang Y4, Zhang C1, He R1, Tao R5.(PubMed)
(1330) A clinical trial testing the safety and efficacy of a standardized Eucommia ulmoides Oliver bark extract to treat hypertension by Greenway F1, Liu Z, Yu Y, Gupta A.(PubMed)
(1331) Antihypertensive effect of Eucommia ulmoides Oliv. extracts in spontaneously hypertensive rats by Luo LF1, Wu WH, Zhou YJ, Yan J, Yang GP, Ouyang DS.(PubMed)
(1332) Eucommia bark pain (PubMed)
(1333) Du Zhong(Complementary and Alternative Healing University)
(1334) Inhibitory Effects of Eucommia ulmoides Oliv. Bark on Scopolamine-Induced Learning and Memory Deficits in Mice. by Kwon SH1, Ma SX1, Joo HJ1, Lee SY1, Jang CG1.(PubMed)
(1335) Neuroprotective effects of Eucommia ulmoides Oliv. Bark on amyloid beta(25-35)-induced learning and memory impairments in mice by Kwon SH1, Lee HK, Kim JA, Hong SI, Kim SY, Jo TH, Park YI, Lee CK, Kim YB, Lee SY, Jang CG.(PubMed)
(1336) Eucommia ulmoides Oliv. Bark. protects against hydrogen peroxide-induced neuronal cell death in SH-SY5Y cells by Kwon SH1, Kim MJ, Ma SX, You IJ, Hwang JY, Oh JH, Kim SY, Kim HC, Lee SY, Jang CG.(PubMed)
(1337) Eucommia ulmoides Oliv.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine by He X1, Wang J2, Li M3, Hao D1, Yang Y4, Zhang C1, He R1, Tao R5.(PubMed)
(1338) Protective effects of Eucommia ulmoides Oliv. bark and leaf on amyloid β-induced cytotoxicity by Zhou Y1, Liang M, Li W, Li K, Li P, Hu Y, Yang Z.(PubMed)
Saturday 25 February 2017
Friday 24 February 2017
The holistic Prevention, Management and Treatment of Dementia due to aging depletion of Kidney Essence -TCM Herbal Shi Hu(Dendrobium)
Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia due to aging depletion of Kidney Essence - Herbal Shi Hu(Dendrobium)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
2. Shi Hu(Dendrobium)
The sweet, bland, slightly cold herb, is also known as Dendrobiu, used in traditional Chinese medicine as anti diabetic(1315)(1316), anti-hyperglycemic((1317)(1318))and anti microbial(1319)(1320) agents caused by yin deficiency and to treat thirsty(1315)(1316), thromboangitis obliterans, chronic throat infection, blurry vision(1321)(1322), weak lower back,... by enhancing the lung, stomach channels(1323).
Phytochemicals
1. Ophiopogonin
2. Ruscogenin
3. β-sitosterol β
4. Stigmasterol
5. Dendrobine
6. Nobilonine
7. 6-hydroxydendrobine
8. Etc.
According to Zunyi Medical College, alkaloids enriched extract fromDendrobium Nobile Lindl. (EDNLA), inhibited paired helical filaments of hyperphosphorylation of tau protein, in neurofibrillary tangles, a pathological feature of Alzheimer's disease (AD)(1324). In rat model administrated intragastrically with different doses of DNLA (20, 40 mg/kg), attenuated lipopolysaccharide (LPS, 100 μg) injecting into the bilateral ventricle, induced hyperphosphorylation of tau protein in hippocampus and protected against LPS-induced apoptosis in brain(1325).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(1311) Qigong for Wellbeing in Dementia and Aging by Stephen Rath
(1312) Chinese Medical Psychiatry: A Textbook & Clinical Manual : Including ... By Bob Flaws, James Lake
(1315) Dendrobium chrysotoxum Lindl. alleviates diabetic retinopathy by preventing retinal inflammation and tight junction protein decrease by Yu Z1, Gong C1, Lu B1, Yang L1, Sheng Y2, Ji L1, Wang Z1.(PubMed)
(1316) Ethanol extract of Dendrobium chrysotoxum Lindl ameliorates diabetic retinopathy and its mechanism. by Gong CY1, Yu ZY1, Lu B1, Yang L1, Sheng YC2, Fan YM1, Ji LL3, Wang ZT1.(PubMed)
(1317) [Studies on anti-hyperglycemic effect and its mechanism of Dendrobium candidum].[Article in Chinese] by Wu HS1, Xu JH, Chen LZ, Sun JJ.(PubMed)
(1318) [Studies on anti-hyperglycemic effect and its mechanism of Clinopodium chinense].[Article in Chinese] by Tian DN1, Wu FH, Ma SC, Li D, Dai Y.(PubMed)
(1319) Antimicrobial activity of endophytic fungi isolated from Dendrobium species in southwestern China by Cui J1, Wang Y, Xing Y, Guo S, Xiao P, Wang M.(PubMed)
(1320) Antimicrobial activity and biodiversity of endophytic fungi in Dendrobium devonianum and Dendrobium thyrsiflorum from Vietnam by Xing YM1, Chen J, Cui JL, Chen XM, Guo SX.(PubMed)
(1321) [Experimental study on preclinical quality control, urgent poison and irritation of Dendrobium aurantiacum eye drops, a class I new drug against diabetic cataract].[Article in Chinese] by Yi YQ1, Yang QH, Su JF, Chen J, Qi H, Chen D, Wei XY.(PubMed)
(1322) [Observation on therapeutic effect of runmushu oral liquid in treating xerophthalmia in postmenopausal women].[Article in Chinese] by Wei D1, Li YH, Zhou WY.(PubMed)
(1323)Shi hu(Complementary and Alternative Healing University)
(1324) Alkaloids enriched extract from Dendrobium nobile Lindl. attenuates tau protein hyperphosphorylation and apoptosis induced by lipopolysaccharide in rat brain by Yang S1, Gong Q1, Wu Q1, Li F1, Lu Y1, Shi J2.(PubMed)
(1325) Eucommia ulmoides Oliv. bark. attenuates 6-hydroxydopamine-induced neuronal cell death through inhibition of oxidative stress in SH-SY5Y cells by Kwon SH1, Ma SX1, Hong SI1, Kim SY2, Lee SY1, Jang CG3.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia due to aging depletion of Kidney Essence - Herbal Shi Hu(Dendrobium)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
2. Shi Hu(Dendrobium)
The sweet, bland, slightly cold herb, is also known as Dendrobiu, used in traditional Chinese medicine as anti diabetic(1315)(1316), anti-hyperglycemic((1317)(1318))and anti microbial(1319)(1320) agents caused by yin deficiency and to treat thirsty(1315)(1316), thromboangitis obliterans, chronic throat infection, blurry vision(1321)(1322), weak lower back,... by enhancing the lung, stomach channels(1323).
Phytochemicals
1. Ophiopogonin
2. Ruscogenin
3. β-sitosterol β
4. Stigmasterol
5. Dendrobine
6. Nobilonine
7. 6-hydroxydendrobine
8. Etc.
According to Zunyi Medical College, alkaloids enriched extract fromDendrobium Nobile Lindl. (EDNLA), inhibited paired helical filaments of hyperphosphorylation of tau protein, in neurofibrillary tangles, a pathological feature of Alzheimer's disease (AD)(1324). In rat model administrated intragastrically with different doses of DNLA (20, 40 mg/kg), attenuated lipopolysaccharide (LPS, 100 μg) injecting into the bilateral ventricle, induced hyperphosphorylation of tau protein in hippocampus and protected against LPS-induced apoptosis in brain(1325).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(1311) Qigong for Wellbeing in Dementia and Aging by Stephen Rath
(1312) Chinese Medical Psychiatry: A Textbook & Clinical Manual : Including ... By Bob Flaws, James Lake
(1315) Dendrobium chrysotoxum Lindl. alleviates diabetic retinopathy by preventing retinal inflammation and tight junction protein decrease by Yu Z1, Gong C1, Lu B1, Yang L1, Sheng Y2, Ji L1, Wang Z1.(PubMed)
(1316) Ethanol extract of Dendrobium chrysotoxum Lindl ameliorates diabetic retinopathy and its mechanism. by Gong CY1, Yu ZY1, Lu B1, Yang L1, Sheng YC2, Fan YM1, Ji LL3, Wang ZT1.(PubMed)
(1317) [Studies on anti-hyperglycemic effect and its mechanism of Dendrobium candidum].[Article in Chinese] by Wu HS1, Xu JH, Chen LZ, Sun JJ.(PubMed)
(1318) [Studies on anti-hyperglycemic effect and its mechanism of Clinopodium chinense].[Article in Chinese] by Tian DN1, Wu FH, Ma SC, Li D, Dai Y.(PubMed)
(1319) Antimicrobial activity of endophytic fungi isolated from Dendrobium species in southwestern China by Cui J1, Wang Y, Xing Y, Guo S, Xiao P, Wang M.(PubMed)
(1320) Antimicrobial activity and biodiversity of endophytic fungi in Dendrobium devonianum and Dendrobium thyrsiflorum from Vietnam by Xing YM1, Chen J, Cui JL, Chen XM, Guo SX.(PubMed)
(1321) [Experimental study on preclinical quality control, urgent poison and irritation of Dendrobium aurantiacum eye drops, a class I new drug against diabetic cataract].[Article in Chinese] by Yi YQ1, Yang QH, Su JF, Chen J, Qi H, Chen D, Wei XY.(PubMed)
(1322) [Observation on therapeutic effect of runmushu oral liquid in treating xerophthalmia in postmenopausal women].[Article in Chinese] by Wei D1, Li YH, Zhou WY.(PubMed)
(1323)Shi hu(Complementary and Alternative Healing University)
(1324) Alkaloids enriched extract from Dendrobium nobile Lindl. attenuates tau protein hyperphosphorylation and apoptosis induced by lipopolysaccharide in rat brain by Yang S1, Gong Q1, Wu Q1, Li F1, Lu Y1, Shi J2.(PubMed)
(1325) Eucommia ulmoides Oliv. bark. attenuates 6-hydroxydopamine-induced neuronal cell death through inhibition of oxidative stress in SH-SY5Y cells by Kwon SH1, Ma SX1, Hong SI1, Kim SY2, Lee SY1, Jang CG3.(PubMed)
Thursday 23 February 2017
The holistic Prevention, Management and Treatment of Dementia under The Microscope of Conventional Medicine: TCM treatment for Dementia due to aging depletion of Kidney Essence
Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia due to aging depletion of Kidney Essence
Based on Chinese ancient medical records, causes of dementia are the results of (*)
1. Dong Chong Cao(Cordyceps)
Dong Chong Cao, the sweet and warm herb, is also known as cordyceps, used in traditional Chinese medicine as anti-arrhythmia, anti-rejection in cornea transplant, antimicrobal effects and to attenuate contraction of smooth muscles, protect against toxins induced kedney and liver diseases, treat chronic lower back pain, impotence, chronic cough and wheezing, blood in phlegm,... as its tonifies lung yin and kidney yang by enhancing the functions of lung and kidney channels(1313).
Phtochemicals
1. Cordyceps polysaccharide
2. Ergosterol
3. Cordycepic acid
4. Lysine
5. Aspartic acid
6. Threonine
7. Taurine
8. Etc.
In ivitro and in vivo model of Alzheimer's disease, methanol extracts of dong chon cao, prevented the beta-amyloid((25-35) induced neuro cell death(1314) and in rat model of ADs, its phytochemical ophioglossoides significantly prevented spatial memory loss by intracranial injection of Abeta(1314), probably through its free radical scavenging activity(1314)
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(1311) Qigong for Wellbeing in Dementia and Aging by Stephen Rath
(1312) Chinese Medical Psychiatry: A Textbook & Clinical Manual : Including ... By Bob Flaws, James Lake
(1313) Dong chong xia cao(Complementary and Alternative Healing University)
(1314) Mycelial extract of Cordyceps ophioglossoides prevents neuronal cell death and ameliorates beta-amyloid peptide-induced memory deficits in rats by Jin DQ1, Park BC, Lee JS, Choi HD, Lee YS, Yang JH, Kim JA.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia due to aging depletion of Kidney Essence
Based on Chinese ancient medical records, causes of dementia are the results of (*)
1. Dong Chong Cao(Cordyceps)
Dong Chong Cao, the sweet and warm herb, is also known as cordyceps, used in traditional Chinese medicine as anti-arrhythmia, anti-rejection in cornea transplant, antimicrobal effects and to attenuate contraction of smooth muscles, protect against toxins induced kedney and liver diseases, treat chronic lower back pain, impotence, chronic cough and wheezing, blood in phlegm,... as its tonifies lung yin and kidney yang by enhancing the functions of lung and kidney channels(1313).
Phtochemicals
1. Cordyceps polysaccharide
2. Ergosterol
3. Cordycepic acid
4. Lysine
5. Aspartic acid
6. Threonine
7. Taurine
8. Etc.
In ivitro and in vivo model of Alzheimer's disease, methanol extracts of dong chon cao, prevented the beta-amyloid((25-35) induced neuro cell death(1314) and in rat model of ADs, its phytochemical ophioglossoides significantly prevented spatial memory loss by intracranial injection of Abeta(1314), probably through its free radical scavenging activity(1314)
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(1311) Qigong for Wellbeing in Dementia and Aging by Stephen Rath
(1312) Chinese Medical Psychiatry: A Textbook & Clinical Manual : Including ... By Bob Flaws, James Lake
(1313) Dong chong xia cao(Complementary and Alternative Healing University)
(1314) Mycelial extract of Cordyceps ophioglossoides prevents neuronal cell death and ameliorates beta-amyloid peptide-induced memory deficits in rats by Jin DQ1, Park BC, Lee JS, Choi HD, Lee YS, Yang JH, Kim JA.(PubMed)
Wednesday 22 February 2017
The holistic Prevention, Management and Treatment of Dementia Induced by toxins - TCM Herbal Shui Fei Zi or Milk thistle
Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia Induced by toxins - Shui Fei Zi or Milk thistle (Silybum marianum)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
B.5. Chinese Herbal medicine for toxins elimination
3. Da Suan(Garlic)
Da Suan(Garlic) used in the treatment of symptoms of dementia(1283)(1284)(1285), including Alzheimer's pathophysiology(1288)(1289) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals aged garlic extract and S-allyl-L-cysteine and extracts(1284) in oxidative stress inhibition(1284) and anti progression involved association of degeneration and neuro inflammatory activity(1286) through neuro protection against amyloid-beta peptide-induced apoptosis(1285) and toxicity(1287).
3.1. In Alzheimer's disease
Strong evidences suggested that deposited amyloid-beta(Abeta) has shown to associate to the progression in Alzheimer's disease (AD)(1290)(1291)(1292). In mouse model induced by neurotoxic amyloid beta protein (Aβ), ethyl acetate fractions of garlic extract exhibited high levels of radical scavenging activity involved cognitive impairment against Aβ-induced neuronal deficit and Aβ-induced learning and memory deficits in vivo(1293). According to Indiana University School of Medicine, the extracts also attenuated synaptic degeneration and neuroinflammatory pathways associated with AD, through major phytochemical S-allyl-L-cysteine (SAC) (1294), including oxidative insults to neurons(1295). In Alzheimer's transgenic model Tg2576, dietary aged garlic extract (AGE) (2%) exhibited anti-amyloidogenic, anti-inflammatory and anti-tangle effects also through its phytochemicals S-allyl-cysteine (SAC) (20 mg/kg) and di-allyl-disulfide (DADS)(1296) without interfering with its antibiotic activity in ameliorate gentamicin (GM)(1297).
3.2. In Parkinson disease
Olfactory dysfunction(1298)(1299) in non-motor functioning and hyposmia(1300)(1301)/anosmia(1302)(1303) are common manifestation in some neurodegenerative disorders caused by oxidative stress (OS) and inflammatory insults(1305), including Parkinson disease. Dietary supplement S-methyl-L-cysteine, a substrate in the catalytic antioxidant system mediated by MSRA showed to protect cells from oxidative damage through its antioxidative effect(1304) when used conjunction with methionine sulfoxide reductase A in Parkinson's-like symptoms(1304).
3.3. In Cognitive impairment
In early cognitive deficits caused by gradual accumulation of beta-amyloid peptide (Abeta) oligomers of Abeta42 species, aged garlic extract, in mice model, prevented progressive behavioral impairment, slowed plaque development, through protection against deterioration of hippocampal based memory(1306), In Alzheimer's disease induced mice model, S-allyl cysteine, a component of aged garlic extract, ameliorated cognitive deficits and oxidative damage in the hippocampus of intracerebroventricular streptozotocin (ICV-STZ)(1308). According to Gyeongsang National University, the effectiveness of aged garlic extracts, in neurodegenerative disorders, notably Alzheimer's disease(AD), may be due to its antioxidant activities in improvement of cognitive impairment against Aβ-induced neuronal deficit(1307).
3.4. In learning and memory
Acute and chronic oral administration of aged garlic extract, in mice using step down latency (SDL) by passive avoidance response and transfer latency (TL) using elevated plus maze, improved learning and memory probably due to cortical acetylcholinesterase (AchE) and reduced glutathione (GSH) levels activities and anti-oxidant property(1309). In oxidative damage and spatiallearning and memory deficits induced mice model, S-allylcysteine exerted its protective effect against reactive oxygen species. Abeta(25-35)-induced hippocampal toxicity and learning deficits, through its free radical scavenging and ameliorated lipid peroxidation activities(1310).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(1283) S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type. by Javed H1, Khan MM, Khan A, Vaibhav K, Ahmad A, Khuwaja G, Ahmed ME, Raza SS, Ashafaq M, Tabassum R, Siddiqui MS, El-Agnaf OM, Safhi MM, Islam F.(PubMed)
(1284) Oxidative insults to neurons and synapse are prevented by aged garlic extract and S-allyl-L-cysteine treatment in the neuronal culture and APP-Tg mouse model by Ray B1, Chauhan NB, Lahiri DK.(PubMed)
(1285) Neuroprotective effect of garlic compounds in amyloid-beta peptide-induced apoptosis in vitro by Peng Q1, Buz'Zard AR, Lau BH.(PubMed)
(1286) The "aged garlic extract:" (AGE) and one of its active ingredients S-allyl-L-cysteine (SAC) as potential preventive and therapeutic agents for Alzheimer's disease (AD) by Ray B1, Chauhan NB, Lahiri DK.(PubMed)
(1287) Neuroprotective effects of garlic a review by Mathew B1, Biju R.(PubMed)
(1288) Garlic extract exhibits antiamyloidogenic activity on amyloid-beta fibrillogenesis: relevance to Alzheimer's disease. by Gupta VB1, Indi SS, Rao KS.(PubMed)
(1289)Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576. by Chauhan NB1.(PubMed)
(1290) Biochemical stages of amyloid-β peptide aggregation and accumulation in the human brain and their association with symptomatic and pathologically preclinical Alzheimer's disease. by Rijal Upadhaya A1, Kosterin I, Kumar S, von Arnim CA, Yamaguchi H, Fändrich M, Walter J, Thal DR.(PubMed)
(1291) Simple in vitro assays to identify amyloid-beta aggregation blockers for Alzheimer's disease therapy. by Guo JP1, Yu S, McGeer PL.(PubMed)
(1292) Inhibition of amyloid-β aggregation in Alzheimer's disease. by Wang Q, Yu X, Li L, Zheng J1.(PubMed)
(1293) Ameliorating effects of aged garlic extracts against Aβ-induced neurotoxicity and cognitive impairment by Jeong JH, Jeong HR, Jo YN, Kim HJ, Shin JH, Heo HJ1.(PubMed)
(1294) The "aged garlic extract:" (AGE) and one of its active ingredients S-allyl-L-cysteine (SAC) as potential preventive and therapeutic agents for Alzheimer's disease (AD) by Ray B1, Chauhan NB, Lahiri DK.(PubMed)
(1295) Oxidative insults to neurons and synapse are prevented by aged garlic extract and S-allyl-L-cysteine treatment in the neuronal culture and APP-Tg mouse model by Ray B1, Chauhan NB, Lahiri DK.(PubMed)
(1296) Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576 by Chauhan NB1.(PubMed)
(1297) Aged garlic extract, garlic powder extract, S-allylcysteine, diallyl sulfide and diallyl disulfide do not interfere with the antibiotic activity of gentamicin. by Maldonado PD1, Chánez-Cárdenas ME, Pedraza-Chaverrí J.(PubMed)
(1298) Olfactory performance and resting state functional connectivity in non-demented drug naïve patients with Parkinson's disease by Sunwoo MK1, Cha J, Ham JH, Song SK, Hong JY, Lee JM, Sohn YH, Lee PH.(PubMed)
(1299) Olfactory performance acts as a cognitive reserve in non-demented patients with Parkinson's disease by Lee JE1, Cho KH1, Ham JH1, Song SK2, Sohn YH1, Lee PH3.(PubMed)
(1300) A population-based study on combined markers for early Parkinson's disease. by Tunc S1, Graf J, Tadic V, Brüggemann N, Schmidt A, Al-Khaled M, Wolff S, Vollstedt EJ, Lorwin A, Hampf J, Piskol L, Klein C, Hagenah J, Kasten M.(PubMed)
(1301) Evolution of prodromal clinical markers of Parkinson disease in a GBA mutation-positive cohort by Beavan M1, McNeill A1, Proukakis C1, Hughes DA2, Mehta A2, Schapira AH1.(PubMed)
(1302) Association of anosmia with autonomic failure in Parkinson disease by Goldstein DS1, Sewell L, Holmes C.(PubMed)
(1303) Association of anosmia with autonomic failure in Parkinson disease by Burke WJ.(PubMed)
(1304) Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms by Wassef R1, Haenold R, Hansel A, Brot N, Heinemann SH, Hoshi T.(PubMed)
(1305) A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects by Youdim KA1, Joseph JA.(PubMed)
(1306) Amelioration of early cognitive deficits by aged garlic extract in Alzheimer's transgenic mice. by Chauhan NB1, Sandoval J.(PubMed)
(1307) Ameliorating effects of aged garlic extracts against Aβ-induced neurotoxicity and cognitive impairment by Jeong JH, Jeong HR, Jo YN, Kim HJ, Shin JH, Heo HJ1.(PubMed)
(1308) S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type by Javed H1, Khan MM, Khan A, Vaibhav K, Ahmad A, Khuwaja G, Ahmed ME, Raza SS, Ashafaq M, Tabassum R, Siddiqui MS, El-Agnaf OM, Safhi MM, Islam F.(PubMed)
(1309) Learning and memory promoting effects of crude garlic extract by Mukherjee D1, Banerjee S1.(PubMed)
(1310) S-Allylcysteine prevents amyloid-beta peptide-induced oxidative stress in rat hippocampus and ameliorates learning deficits by Pérez-Severiano F1, Salvatierra-Sánchez R, Rodríguez-Pérez M, Cuevas-Martínez EY, Guevara J, Limón D, Maldonado PD, Medina-Campos ON, Pedraza-Chaverrí J, Santamaría A.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia Induced by toxins - Shui Fei Zi or Milk thistle (Silybum marianum)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
B.5. Chinese Herbal medicine for toxins elimination
3. Da Suan(Garlic)
Da Suan(Garlic) used in the treatment of symptoms of dementia(1283)(1284)(1285), including Alzheimer's pathophysiology(1288)(1289) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals aged garlic extract and S-allyl-L-cysteine and extracts(1284) in oxidative stress inhibition(1284) and anti progression involved association of degeneration and neuro inflammatory activity(1286) through neuro protection against amyloid-beta peptide-induced apoptosis(1285) and toxicity(1287).
3.1. In Alzheimer's disease
Strong evidences suggested that deposited amyloid-beta(Abeta) has shown to associate to the progression in Alzheimer's disease (AD)(1290)(1291)(1292). In mouse model induced by neurotoxic amyloid beta protein (Aβ), ethyl acetate fractions of garlic extract exhibited high levels of radical scavenging activity involved cognitive impairment against Aβ-induced neuronal deficit and Aβ-induced learning and memory deficits in vivo(1293). According to Indiana University School of Medicine, the extracts also attenuated synaptic degeneration and neuroinflammatory pathways associated with AD, through major phytochemical S-allyl-L-cysteine (SAC) (1294), including oxidative insults to neurons(1295). In Alzheimer's transgenic model Tg2576, dietary aged garlic extract (AGE) (2%) exhibited anti-amyloidogenic, anti-inflammatory and anti-tangle effects also through its phytochemicals S-allyl-cysteine (SAC) (20 mg/kg) and di-allyl-disulfide (DADS)(1296) without interfering with its antibiotic activity in ameliorate gentamicin (GM)(1297).
3.2. In Parkinson disease
Olfactory dysfunction(1298)(1299) in non-motor functioning and hyposmia(1300)(1301)/anosmia(1302)(1303) are common manifestation in some neurodegenerative disorders caused by oxidative stress (OS) and inflammatory insults(1305), including Parkinson disease. Dietary supplement S-methyl-L-cysteine, a substrate in the catalytic antioxidant system mediated by MSRA showed to protect cells from oxidative damage through its antioxidative effect(1304) when used conjunction with methionine sulfoxide reductase A in Parkinson's-like symptoms(1304).
3.3. In Cognitive impairment
In early cognitive deficits caused by gradual accumulation of beta-amyloid peptide (Abeta) oligomers of Abeta42 species, aged garlic extract, in mice model, prevented progressive behavioral impairment, slowed plaque development, through protection against deterioration of hippocampal based memory(1306), In Alzheimer's disease induced mice model, S-allyl cysteine, a component of aged garlic extract, ameliorated cognitive deficits and oxidative damage in the hippocampus of intracerebroventricular streptozotocin (ICV-STZ)(1308). According to Gyeongsang National University, the effectiveness of aged garlic extracts, in neurodegenerative disorders, notably Alzheimer's disease(AD), may be due to its antioxidant activities in improvement of cognitive impairment against Aβ-induced neuronal deficit(1307).
3.4. In learning and memory
Acute and chronic oral administration of aged garlic extract, in mice using step down latency (SDL) by passive avoidance response and transfer latency (TL) using elevated plus maze, improved learning and memory probably due to cortical acetylcholinesterase (AchE) and reduced glutathione (GSH) levels activities and anti-oxidant property(1309). In oxidative damage and spatiallearning and memory deficits induced mice model, S-allylcysteine exerted its protective effect against reactive oxygen species. Abeta(25-35)-induced hippocampal toxicity and learning deficits, through its free radical scavenging and ameliorated lipid peroxidation activities(1310).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(1283) S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type. by Javed H1, Khan MM, Khan A, Vaibhav K, Ahmad A, Khuwaja G, Ahmed ME, Raza SS, Ashafaq M, Tabassum R, Siddiqui MS, El-Agnaf OM, Safhi MM, Islam F.(PubMed)
(1284) Oxidative insults to neurons and synapse are prevented by aged garlic extract and S-allyl-L-cysteine treatment in the neuronal culture and APP-Tg mouse model by Ray B1, Chauhan NB, Lahiri DK.(PubMed)
(1285) Neuroprotective effect of garlic compounds in amyloid-beta peptide-induced apoptosis in vitro by Peng Q1, Buz'Zard AR, Lau BH.(PubMed)
(1286) The "aged garlic extract:" (AGE) and one of its active ingredients S-allyl-L-cysteine (SAC) as potential preventive and therapeutic agents for Alzheimer's disease (AD) by Ray B1, Chauhan NB, Lahiri DK.(PubMed)
(1287) Neuroprotective effects of garlic a review by Mathew B1, Biju R.(PubMed)
(1288) Garlic extract exhibits antiamyloidogenic activity on amyloid-beta fibrillogenesis: relevance to Alzheimer's disease. by Gupta VB1, Indi SS, Rao KS.(PubMed)
(1289)Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576. by Chauhan NB1.(PubMed)
(1290) Biochemical stages of amyloid-β peptide aggregation and accumulation in the human brain and their association with symptomatic and pathologically preclinical Alzheimer's disease. by Rijal Upadhaya A1, Kosterin I, Kumar S, von Arnim CA, Yamaguchi H, Fändrich M, Walter J, Thal DR.(PubMed)
(1291) Simple in vitro assays to identify amyloid-beta aggregation blockers for Alzheimer's disease therapy. by Guo JP1, Yu S, McGeer PL.(PubMed)
(1292) Inhibition of amyloid-β aggregation in Alzheimer's disease. by Wang Q, Yu X, Li L, Zheng J1.(PubMed)
(1293) Ameliorating effects of aged garlic extracts against Aβ-induced neurotoxicity and cognitive impairment by Jeong JH, Jeong HR, Jo YN, Kim HJ, Shin JH, Heo HJ1.(PubMed)
(1294) The "aged garlic extract:" (AGE) and one of its active ingredients S-allyl-L-cysteine (SAC) as potential preventive and therapeutic agents for Alzheimer's disease (AD) by Ray B1, Chauhan NB, Lahiri DK.(PubMed)
(1295) Oxidative insults to neurons and synapse are prevented by aged garlic extract and S-allyl-L-cysteine treatment in the neuronal culture and APP-Tg mouse model by Ray B1, Chauhan NB, Lahiri DK.(PubMed)
(1296) Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576 by Chauhan NB1.(PubMed)
(1297) Aged garlic extract, garlic powder extract, S-allylcysteine, diallyl sulfide and diallyl disulfide do not interfere with the antibiotic activity of gentamicin. by Maldonado PD1, Chánez-Cárdenas ME, Pedraza-Chaverrí J.(PubMed)
(1298) Olfactory performance and resting state functional connectivity in non-demented drug naïve patients with Parkinson's disease by Sunwoo MK1, Cha J, Ham JH, Song SK, Hong JY, Lee JM, Sohn YH, Lee PH.(PubMed)
(1299) Olfactory performance acts as a cognitive reserve in non-demented patients with Parkinson's disease by Lee JE1, Cho KH1, Ham JH1, Song SK2, Sohn YH1, Lee PH3.(PubMed)
(1300) A population-based study on combined markers for early Parkinson's disease. by Tunc S1, Graf J, Tadic V, Brüggemann N, Schmidt A, Al-Khaled M, Wolff S, Vollstedt EJ, Lorwin A, Hampf J, Piskol L, Klein C, Hagenah J, Kasten M.(PubMed)
(1301) Evolution of prodromal clinical markers of Parkinson disease in a GBA mutation-positive cohort by Beavan M1, McNeill A1, Proukakis C1, Hughes DA2, Mehta A2, Schapira AH1.(PubMed)
(1302) Association of anosmia with autonomic failure in Parkinson disease by Goldstein DS1, Sewell L, Holmes C.(PubMed)
(1303) Association of anosmia with autonomic failure in Parkinson disease by Burke WJ.(PubMed)
(1304) Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms by Wassef R1, Haenold R, Hansel A, Brot N, Heinemann SH, Hoshi T.(PubMed)
(1305) A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects by Youdim KA1, Joseph JA.(PubMed)
(1306) Amelioration of early cognitive deficits by aged garlic extract in Alzheimer's transgenic mice. by Chauhan NB1, Sandoval J.(PubMed)
(1307) Ameliorating effects of aged garlic extracts against Aβ-induced neurotoxicity and cognitive impairment by Jeong JH, Jeong HR, Jo YN, Kim HJ, Shin JH, Heo HJ1.(PubMed)
(1308) S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type by Javed H1, Khan MM, Khan A, Vaibhav K, Ahmad A, Khuwaja G, Ahmed ME, Raza SS, Ashafaq M, Tabassum R, Siddiqui MS, El-Agnaf OM, Safhi MM, Islam F.(PubMed)
(1309) Learning and memory promoting effects of crude garlic extract by Mukherjee D1, Banerjee S1.(PubMed)
(1310) S-Allylcysteine prevents amyloid-beta peptide-induced oxidative stress in rat hippocampus and ameliorates learning deficits by Pérez-Severiano F1, Salvatierra-Sánchez R, Rodríguez-Pérez M, Cuevas-Martínez EY, Guevara J, Limón D, Maldonado PD, Medina-Campos ON, Pedraza-Chaverrí J, Santamaría A.(PubMed)
Tuesday 21 February 2017
The holistic Prevention, Management and Treatment of Dementia induced by Toxins - TCM Herbal Xiu Hui Xiang (Fennel)
Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia Induced by toxins - Shui Fei Zi or Milk thistle (Silybum marianum)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
B.5. Chinese Herbal medicine for toxins elimination
2. Xiu Hui Xiang (Fennel)
Xiu Hui Xiang, the acrid and warm herb, is also known as fennel, native to Mediterranean, used in traditional Chinese medicine as anti microbal(1232)(1233), antioxidant(1234)(1235), emmenagogue(1236), estrogenic(1244) and androgenic(1245) agents and to prevent bone loss in postmenopausal osteoporosis(1237)(1238), treat hepatic fibrosis(1239), gastro intestine disorder(1240)(1241), decrease hair thickness(1243) and increase flow of breast milk(1242) by enhancing function of liver, kidney, spleen, stomach channels(1231).
Phytoshemicals
1. Linoleic acid
2. Palmitic acid
3. Arachidic acid
4. Behenic acid
5. Quercetin
6. Phytosteryl b-fructofuranoside
7. 7-hydroxycoumarin
8. 6,7-dihydroxycoumarin
9. Oleanolic acid
10. Sitosterol
11. Fenchone
12. α-pinene
13. Limonene
14. β-Pinene
15. β-Myrcene
16. α-Phellandrene
17. P-Cymol
18. Etc.
Xiu Hui Xiang (Fennel) used in the treatment of symptoms of neurodegenerative disorder, including age-related mental problems of Alzheimer's disease(1246)) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals in acetylcholinesterase inhibition(1246) and anti inflammation(1247) through suppression of the nuclear factor-kappaB activation pathway(1247) involved stress, cell signaling, free radicals, oxidized LDL activities(1248)(1249)(1250)(1251).
2.1. In anxiolytic activity
Anxiety is a condition of neurodisorder of unpleasant state of inner turmoil with fear of the presence and future, according to Diagnostic and Statistical Manual of Mental Disorders American Psychiatric Association, effecting patients with dementia, included familial Alzheimer's disease(1252) and other neuropsychiatric disorders(1254). Fennel, a medical herb used in many cultures, has shown effectively in treating anxiety, epidemiologically. In adult Swiss albino male mice, oral administration 100 and 200 mg/kg doses of fennel essential oil significantly increased percent number of entries and time spent in open arms in elevated plus maze (EPM) test(1255).
2.2. In learning and memory
Fennels, the most widely used herbal plant in the world(1256) used in traditional Iranian medicine and modern phytotherapy for memoryenhancing(1257). In Alzheimer's disease, induced a decline of cognitive abilities in mice model, fennel extract successfully ameliorated the amnesic effect of scopolamine (0.4 mg/kg) and aging- induced memory deficits in 8 days in dose-depend manner, through increased step-down latency and acetylcholinesterase inhibition(1258).
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia Induced by toxins - Shui Fei Zi or Milk thistle (Silybum marianum)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
B.5. Chinese Herbal medicine for toxins elimination
2. Xiu Hui Xiang (Fennel)
Xiu Hui Xiang, the acrid and warm herb, is also known as fennel, native to Mediterranean, used in traditional Chinese medicine as anti microbal(1232)(1233), antioxidant(1234)(1235), emmenagogue(1236), estrogenic(1244) and androgenic(1245) agents and to prevent bone loss in postmenopausal osteoporosis(1237)(1238), treat hepatic fibrosis(1239), gastro intestine disorder(1240)(1241), decrease hair thickness(1243) and increase flow of breast milk(1242) by enhancing function of liver, kidney, spleen, stomach channels(1231).
Phytoshemicals
1. Linoleic acid
2. Palmitic acid
3. Arachidic acid
4. Behenic acid
5. Quercetin
6. Phytosteryl b-fructofuranoside
7. 7-hydroxycoumarin
8. 6,7-dihydroxycoumarin
9. Oleanolic acid
10. Sitosterol
11. Fenchone
12. α-pinene
13. Limonene
14. β-Pinene
15. β-Myrcene
16. α-Phellandrene
17. P-Cymol
18. Etc.
Xiu Hui Xiang (Fennel) used in the treatment of symptoms of neurodegenerative disorder, including age-related mental problems of Alzheimer's disease(1246)) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals in acetylcholinesterase inhibition(1246) and anti inflammation(1247) through suppression of the nuclear factor-kappaB activation pathway(1247) involved stress, cell signaling, free radicals, oxidized LDL activities(1248)(1249)(1250)(1251).
2.1. In anxiolytic activity
Anxiety is a condition of neurodisorder of unpleasant state of inner turmoil with fear of the presence and future, according to Diagnostic and Statistical Manual of Mental Disorders American Psychiatric Association, effecting patients with dementia, included familial Alzheimer's disease(1252) and other neuropsychiatric disorders(1254). Fennel, a medical herb used in many cultures, has shown effectively in treating anxiety, epidemiologically. In adult Swiss albino male mice, oral administration 100 and 200 mg/kg doses of fennel essential oil significantly increased percent number of entries and time spent in open arms in elevated plus maze (EPM) test(1255).
2.2. In learning and memory
Fennels, the most widely used herbal plant in the world(1256) used in traditional Iranian medicine and modern phytotherapy for memoryenhancing(1257). In Alzheimer's disease, induced a decline of cognitive abilities in mice model, fennel extract successfully ameliorated the amnesic effect of scopolamine (0.4 mg/kg) and aging- induced memory deficits in 8 days in dose-depend manner, through increased step-down latency and acetylcholinesterase inhibition(1258).
Herbal medicine for Heart Qi deficiency
The Best Way to prevent, treat your disease, including dementia
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(1232) Benefit of supplements in functional dyspepsia after treatment of Helicobacter pylori. by Pellicano R1, Ribaldone DG, Saracco GM, Leone N, De Angelis C, Arrigoni A, Morello E, Sapone N, Cisarò F, Astegiano M.(PubMed)
(1233) Antimicrobial activity of plant essential oils against bacterial and fungal species involved in food poisoning and/or food decay. by Lixandru BE1, Drăcea NO, Dragomirescu CC, Drăgulescu EC, Coldea IL, Anton L, Dobre E, Rovinaru C, Codiţă I.(PubMed)
(1234) Antioxidant and anticarcinogenic effects of methanolic extract and volatile oil of fennel seeds (Foeniculum vulgare).by Mohamad RH1, El-Bastawesy AM, Abdel-Monem MG, Noor AM, Al-Mehdar HA, Sharawy SM, El-Merzabani MM.(PubMed)
(1235) Assessment of free radical scavenging potential and oxidative DNA damage preventive activity of Trachyspermum ammi L. (carom) and Foeniculum vulgare Mill. (fennel) seed extracts. by Goswami N1, Chatterjee S1.(PubMed)
(1236) Medicinal properties of Foeniculum vulgare Mill. in traditional Iranian medicine and modern phytotherapy. by Rahimi R1, Ardekani MR.(PubMed)
(1237) Potent inhibitory effect of Foeniculum vulgare Miller extract on osteoclast differentiation and ovariectomy-induced bone loss. by Kim TH1, Kim HJ, Lee SH, Kim SY.(PubMed)
(1238) Effects of Foeniculum vulgare ethanol extract on osteogenesis in human mecenchymal stem cells by Mahmoudi Z1, Soleimani M2, Saidi A1, Khamisipour G3, Azizsoltani A4.(PubMed)
(1239) [Antioxidant effects of the Uygur herb, Foeniculum Vulgare Mill, in a rat model of hepatic fibrosis].[Article in Chinese] by Zhang ZG1, Lu XB, Xiao L, Tang L, Zhang LJ, Zhang T, Zhan XY, Ma XM, Zhang YX.(PubMed)
(1240) Anti-inflammatory and cytoprotective effects of selected Pakistani medicinal plants in Helicobacter pylori-infected gastric epithelial cells by Zaidi SF1, Muhammad JS, Shahryar S, Usmanghani K, Gilani AH, Jafri W, Sugiyama T.(PubMed)
(1241) Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum, Foeniculum vulgare, Sambucus nigra, and Cassia augustifolia for chronic constipation. by Picon PD1, Picon RV, Costa AF, Sander GB, Amaral KM, Aboy AL, Henriques AT.(PubMed)
(1242) Fennel and anise as estrogenic agents by Albert-Puleo M.(PubMed)
(1243) The effect of fennel (Foeniculum vulgare) gel 3% in decreasing hair thickness in idiopathic mild to moderate hirsutism, A randomized placebo controlled clinical trial by Akha O1, Rabiei K2, Kashi Z1, Bahar A1, Zaeif-Khorasani E1, Kosaryan M3, Saeedi M4, Ebrahimzadeh MA5, Emadian O6.(PubMed)
(1244)
(1245) Antihirsutism activity of Fennel (fruits of Foeniculum vulgare) extract. A double-blind placebo controlled study. by Javidnia K1, Dastgheib L, Mohammadi Samani S, Nasiri A.(PubMed)(1246) Cholinergic basis of memory-strengthening effect of Foeniculum vulgare Linn. by Joshi H1, Parle M(PubMed)
(1247) Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning by Aggarwal BB1, Shishodia S.(PubMed)
(1248) Introduction to NF-
B: players, pathways, perspectives by T D Gilmore1(Oncogene)
(1249) The NF-κB regulatory network by Allan R. Brasier(Springer link)
(1250) The Rel/NF-kappaB signal transduction pathway: introduction. by Gilmore TD1.(PubMed)
(1251) Integrating cell-signalling pathways with NF-κB and IKK function by Neil D. Perkins(Nature view)
(1252) Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network by Ringman JM1, Liang LJ2, Zhou Y3, Vangala S2, Teng E4, Kremen S3, Wharton D3, Goate A5, Marcus DS6, Farlow M7, Ghetti B8, McDade E9, Masters CL10,Mayeux RP11, Rossor M12, Salloway S13, Schofield PR14, Cummings JL15, Buckles V6, Bateman R6, Morris JC6; Dominantly Inherited Alzheimer Network.(PubMed)
(1253) The course of neuropsychiatric symptoms in dementia: a 3-year longitudinal study. by Brodaty H1, Connors MH2, Xu J2, Woodward M3, Ames D4; PRIME study group.(PubMed)
(1254) Neuropsychiatric symptoms, APOE ε4, and the risk of incident dementia: a population-based study. by Pink A1, Stokin GB1, Bartley MM1, Roberts RO1, Sochor O1, Machulda MM1, Krell-Roesch J1, Knopman DS1, Acosta JI1, Christianson TJ1, Pankratz VS1,Mielke MM1, Petersen RC1, Geda YE2.(PubMed)
(1255) Evaluation of anxiolytic activity of the essential oil of the aerial part of Foeniculum vulgare Miller in mice by Mesfin M, Asres K, Shibeshi W1.(PubMed)
(1256) Foeniculum vulgare Mill: a review of its botany, phytochemistry, pharmacology, contemporary application, and toxicology by Badgujar SB1, Patel VV1, Bandivdekar AH1.(PubMed)
(1257) Medicinal properties of Foeniculum vulgare Mill. in traditional Iranian medicine and modern phytotherapy by Rahimi R1, Ardekani MR.(PubMed)
The Best Way to prevent, treat your disease, including dementia
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(1232) Benefit of supplements in functional dyspepsia after treatment of Helicobacter pylori. by Pellicano R1, Ribaldone DG, Saracco GM, Leone N, De Angelis C, Arrigoni A, Morello E, Sapone N, Cisarò F, Astegiano M.(PubMed)
(1233) Antimicrobial activity of plant essential oils against bacterial and fungal species involved in food poisoning and/or food decay. by Lixandru BE1, Drăcea NO, Dragomirescu CC, Drăgulescu EC, Coldea IL, Anton L, Dobre E, Rovinaru C, Codiţă I.(PubMed)
(1234) Antioxidant and anticarcinogenic effects of methanolic extract and volatile oil of fennel seeds (Foeniculum vulgare).by Mohamad RH1, El-Bastawesy AM, Abdel-Monem MG, Noor AM, Al-Mehdar HA, Sharawy SM, El-Merzabani MM.(PubMed)
(1235) Assessment of free radical scavenging potential and oxidative DNA damage preventive activity of Trachyspermum ammi L. (carom) and Foeniculum vulgare Mill. (fennel) seed extracts. by Goswami N1, Chatterjee S1.(PubMed)
(1236) Medicinal properties of Foeniculum vulgare Mill. in traditional Iranian medicine and modern phytotherapy. by Rahimi R1, Ardekani MR.(PubMed)
(1237) Potent inhibitory effect of Foeniculum vulgare Miller extract on osteoclast differentiation and ovariectomy-induced bone loss. by Kim TH1, Kim HJ, Lee SH, Kim SY.(PubMed)
(1238) Effects of Foeniculum vulgare ethanol extract on osteogenesis in human mecenchymal stem cells by Mahmoudi Z1, Soleimani M2, Saidi A1, Khamisipour G3, Azizsoltani A4.(PubMed)
(1239) [Antioxidant effects of the Uygur herb, Foeniculum Vulgare Mill, in a rat model of hepatic fibrosis].[Article in Chinese] by Zhang ZG1, Lu XB, Xiao L, Tang L, Zhang LJ, Zhang T, Zhan XY, Ma XM, Zhang YX.(PubMed)
(1240) Anti-inflammatory and cytoprotective effects of selected Pakistani medicinal plants in Helicobacter pylori-infected gastric epithelial cells by Zaidi SF1, Muhammad JS, Shahryar S, Usmanghani K, Gilani AH, Jafri W, Sugiyama T.(PubMed)
(1241) Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum, Foeniculum vulgare, Sambucus nigra, and Cassia augustifolia for chronic constipation. by Picon PD1, Picon RV, Costa AF, Sander GB, Amaral KM, Aboy AL, Henriques AT.(PubMed)
(1242) Fennel and anise as estrogenic agents by Albert-Puleo M.(PubMed)
(1243) The effect of fennel (Foeniculum vulgare) gel 3% in decreasing hair thickness in idiopathic mild to moderate hirsutism, A randomized placebo controlled clinical trial by Akha O1, Rabiei K2, Kashi Z1, Bahar A1, Zaeif-Khorasani E1, Kosaryan M3, Saeedi M4, Ebrahimzadeh MA5, Emadian O6.(PubMed)
(1244)
(1245) Antihirsutism activity of Fennel (fruits of Foeniculum vulgare) extract. A double-blind placebo controlled study. by Javidnia K1, Dastgheib L, Mohammadi Samani S, Nasiri A.(PubMed)(1246) Cholinergic basis of memory-strengthening effect of Foeniculum vulgare Linn. by Joshi H1, Parle M(PubMed)
(1247) Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning by Aggarwal BB1, Shishodia S.(PubMed)
(1248) Introduction to NF-
B: players, pathways, perspectives by T D Gilmore1(Oncogene)(1249) The NF-κB regulatory network by Allan R. Brasier(Springer link)
(1250) The Rel/NF-kappaB signal transduction pathway: introduction. by Gilmore TD1.(PubMed)
(1251) Integrating cell-signalling pathways with NF-κB and IKK function by Neil D. Perkins(Nature view)
(1252) Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network by Ringman JM1, Liang LJ2, Zhou Y3, Vangala S2, Teng E4, Kremen S3, Wharton D3, Goate A5, Marcus DS6, Farlow M7, Ghetti B8, McDade E9, Masters CL10,Mayeux RP11, Rossor M12, Salloway S13, Schofield PR14, Cummings JL15, Buckles V6, Bateman R6, Morris JC6; Dominantly Inherited Alzheimer Network.(PubMed)
(1253) The course of neuropsychiatric symptoms in dementia: a 3-year longitudinal study. by Brodaty H1, Connors MH2, Xu J2, Woodward M3, Ames D4; PRIME study group.(PubMed)
(1254) Neuropsychiatric symptoms, APOE ε4, and the risk of incident dementia: a population-based study. by Pink A1, Stokin GB1, Bartley MM1, Roberts RO1, Sochor O1, Machulda MM1, Krell-Roesch J1, Knopman DS1, Acosta JI1, Christianson TJ1, Pankratz VS1,Mielke MM1, Petersen RC1, Geda YE2.(PubMed)
(1255) Evaluation of anxiolytic activity of the essential oil of the aerial part of Foeniculum vulgare Miller in mice by Mesfin M, Asres K, Shibeshi W1.(PubMed)
(1256) Foeniculum vulgare Mill: a review of its botany, phytochemistry, pharmacology, contemporary application, and toxicology by Badgujar SB1, Patel VV1, Bandivdekar AH1.(PubMed)
(1257) Medicinal properties of Foeniculum vulgare Mill. in traditional Iranian medicine and modern phytotherapy by Rahimi R1, Ardekani MR.(PubMed)
Monday 20 February 2017
The holistic Prevention, Management and Treatment of Dementia due to Blood Stasis -TCM Herbal Polygonum multiflorum (He shou wu)
Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia Induced by Blood Stasis -TCM Herbal Polygonum multiflorum (He shou wu)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
B.4. Dementia due to Blood Stasis
According to Chinese medical literaure over 3000 years of history, blood stasis may be caused by spleen qi deficiency, but in most cases, it is due to heart qi deficiency cause of inability in transport nutrients to the body organs and cells, including the brain. Prolong period of malnutrition of brain cells may induce abnormal function of brain's cells in information transmitting or death of neurons, cognitive impairments(844), including learning and memory deficits(842) and changes in brain tissues and behavior patterns(843)(842). Blood statsis induced by cold(1142), emotional disorder(1143), aging(1144),chronic illnesses and consumptive disease(1145), can overload the heart capacity, contributing to long-term hypertension(1146) due to decreased or impeded blood flow(1147) causes of hypo-perfusion in cerebral blood flow or acute focal stroke in memory-related cerebral parenchyma induced progression of cognitive decline(*).
2. Polygonum multiflorum (He shou wu)
He Shu Wu or Ye Jiao Teng or Shu Wu is also known as Fleece flower root or Fo-ti.
a. The prepared herb is astringent with some sweetness, mildly warm
b. The raw herb is bitter, sweet and neutral
used in TCM to treatment of hyperlipemia(1173), neurasthenia(1174), split personality(1174), promoted hair grown(1175) and prevent hair loss(1176) due to aging, skin rash due to inflammation(1177), etc., as it tonifies and benefits the essence and blood, expels toxins, moistens the intestines, etc. by enhancing the (The prepared herb) liver and kidney channels and (The raw herb) liver, heart and large intestine channels(1178).
Phytochemicals
1. Polygoacetophenoside
2. Chrysophanol
3. Emodin
4. Rhein
5. Emodin-6
6. Physcion
7. Chrysophanic acid
8. Anthrone
9. beta-sitosterol
10. 2,3,5,4′-tetrahydroxystibene-2O-b-D-glucoside
11. Quercetin-3-O-galactoside
12. Querctin-3-O-arabinoside
13. Lecithin
14. Etc.
2.1. In Alzheimer's disease
Polygonum multiflorum extract, significantly improved AD patients with total effective rate of 93.33% in clinical trial, according to Third XiangyaHospital(1179). In rat model, induced Alzheimer's disease by injecting Abeta 1-40, the herb exhibited improvement of learning and memory ability, through expression of the fluidity of mitochondria membrane and the activity of mitochondrial COX(1180) and ameliorated hippocampal synapses count and synaptophysin expression(1181). In cognitive deficits induced by Abeta25-35,Polygonum multiflorum water extract, also significantly ameliorated the cognitive deficits, probably due to its antioxidant properties(1182).
2.2. In Parkinson disease
Strong evidences suggested that agricultural chemicals and environment toxins, such as dithiocarbamate fungicides, impacted dopamine systems has shown to associate to the development of Parkinson's disease,(1184)(1185). In nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice model, ethanol-soluble PME (PME-I) water extracts from Polygonum multiflorum, improved locomotor activity, motor incoordination, and declines of dopamine level, probably through phytochemicals, in the ethanol-soluble fraction(1183).
2.3. In neuroprotective effects
In focal cerebral ischemia mice, hexane extracts of Polygonum multiflorum, exhibited its neuroprotective effects though significantly decreased infarct size and improved neurological and motor function, (1186) and attenuated glutamate-induced neurotoxicity in a concentration-dependent manner and prevented apoptosis of cortical neurons(1187), in HT22 hippocampal cells(1188), probably through it antioxidant activity. According to Xuanwu Hospital of Capital Medical University, 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) extract from Polygonum multiflorum, also improved mitochondrial function, decreased oxidative stress and inhibited apoptosis against induced cytotoxicity in human dopaminergic neuroblastoma SH-SY5Y cells(1188).
2.4. In learning and memory
Dietary supplementation with either ethanol or water extracts of Polygonummultiflorum have shown to reduce brain pathological changes and promote learning and memory ability(1191)(1192). In male Sprague-Dawley rats, injected with beta amyloid (Aβ), tetrahydroxystilbene glucoside, an active chemical constituent of extract from Polygonum multiflorum, significantly improved the learning and memory, through protecting synaptic structure and function(1189) and learning and/or memory ability of aged rats by increasedBeta-secretase 1 (BACE1), a beta-site amyloid precursor protein cleaving enzyme 1 and decreased ADAM10 (metallopeptidase domain 10), a protein associated to the development of Alzheimer's disease(1190).
B.5. According to TCM philosophy, dementia is also to be induced by the combination/or of Kidney essence vacuity and toxin (turbid phlegm).
C.5.1. Dementia due to toxins accumulation
Toxins accumulation in internal organs disturbed the balance of immunity(1213)(1214) may cause impairment of food intake regulation(1215), exhibition of phlegm(1208)(1208)(1210), retention of fluid(1211)(1212) and blood statsis(1209) induced early the onset of dementia, in aging population with depletion of kidney-essence(1208)(1209), according to traditional Chinese medicine.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(842) Folate deficiency in rat pups during weaning causes learning and memory deficits. by Berrocal-Zaragoza MI1, Sequeira JM1, Murphy MM2, Fernandez-Ballart JD2, Abdel Baki SG3, Bergold PJ3, Quadros EV1.(PubMed)
(843) Changes in brain tissue and behavior patterns induced by single short-term fasting in mice. by Hisatomi Y1, Asakura K, Kugino K, Kurokawa M, Asakura T, Nakata K.(PubMed)
(844) Combined low calcium and lack magnesium is a risk factor for motor deficit in mice. by Taniguchi R1, Nakagawasai O, Tan-no K, Yamadera F, Nemoto W, Sato S, Yaoita F, Tadano T.(PubMed)
(1173) [Blood lipid-regulation of stilbene glycoside from polygonum multiflorum].[Article in Chinese] by Gao X1, Hu YJ, Fu LC.(PubMed)
(1174) Polygonum multiflorum extracts improve cognitive performance in senescence accelerated mice by Chan YC1, Wang MF, Chang HC.(PubMed)
(1175) In vivo hair growth-stimulating effect of medicinal plant extract on BALB/c nude mice by Begum S1, Gu LJ, Lee MR, Li Z, Li JJ, Hossain MJ, Wang YB, Sung CK.(PubMed)
(1176) [Impact of 2, 3-dihydrocyclopentacoumarins to growth of transgenic hairy roots of Polygonum multiflorum and accumulation of stilbene glucosides].[Article in Chinese] by Liu L1, Zhou L, Zhang M, Yu R.(PubMed)
(1177) [Treatment of chronic primary glomerulopathy patients of Shen deficiency and dampness heat syndrome by yishen qingli granule combined low-dose Tripterygium wilfordii multiglycoside tablet: a clinical efficacy observation].[Article in Chinese] by Sheng MX1, Sun W2, Xing CY3, Yuan FH4, Tang SF5, Xiong PH6, Ma JP7, Zhou D2, Gao K2, Jiang Y2, Chen JH2, Mao HJ3, Mou J4, Luo YZ5, Wei MG6, Liu CX7.(PubMed)
(1178) HE SHOU WU (Complementary and Alternative Healing University)
(1179) [Effect of compound Polygonum multiflorum extract on Alzheimer's disease].[Article in Chinese] by Chen L1, Huang J, Xue L.(PubMed)
(1180) Effect of polygonum multiflorum on the fluidity of the mitochondria membrane and activity of COX in the hippocampus of rats with Abeta 1-40-induced Alzheimer's disease. by Hou DR1, Wang Y, Xue L, Tian Y, Chen K, Song Z, Yang QD.(PubMed)
(1181) Changes in hippocampal synapses and learning-memory abilities in age-increasing rats and effects of tetrahydroxystilbene glucoside in aged rats by Wang R1, Tang Y, Feng B, Ye C, Fang L, Zhang L, Li L.(PubMed)
(1182) Protective effect of Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 induced cognitive deficits in mice by Um MY1, Choi WH, Aan JY, Kim SR, Ha TY.(PubMed)
(1183) Neuroprotective effects of Polygonum multiflorum on nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice by Li X1, Matsumoto K, Murakami Y, Tezuka Y, Wu Y, Kadota S.(PubMed)
(1184) The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease by Thiruchelvam M1, Richfield EK, Baggs RB, Tank AW, Cory-Slechta DA(PubMed)
(1185) Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models? by Cicchetti F1, Drouin-Ouellet J, Gross RE.(PubMed)
(1186) Hexane extracts of Polygonum multiflorum improve tissue and functional outcome following focal cerebral ischemia in mice by Lee SV1, Choi KH1, Choi YW2, Hong JW1, Baek JU1, Choi BT1, Shin HK1.(PubMed)
(1187) Hexane extract from Polygonum multiflorum attenuates glutamate-induced apoptosis in primary cultured cortical neurons by Jang JY1, Kim HN, Kim YR, Choi YW, Choi YH, Lee JH, Shin HK, Choi BT.(PubMed)
(1188) Tetrahydroxystilbene glucoside protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity by Sun FL1, Zhang L, Zhang RY, Li L.(PubMed)
(1189) Tetrahydroxystilbene glucoside improves the learning and memory of amyloid-β(₁₋₄₂)-injected rats and may be connected to synaptic changes in the hippocampus by Zhou L1, Hou Y, Yang Q, Du X, Li M, Yuan M, Zhou Z.(PubMed)
(1190) Tetrahydroxystilbene glucoside improves learning and (or) memory ability of aged rats and may be connected to the APP pathway by Hou Y1, Yang Q, Zhou L, Du X, Li M, Yuan M, Zhou Z, Li Z.(PubMed)
(1191) Beneficial effects of different Polygonum multiflorum Thunb. extracts on memory and hippocampus morphology by Chan YC1, Cheng FC, Wang MF.(PubMed)
(1192) Polygonum multiflorum extracts improve cognitive performance in senescence accelerated mice. by Chan YC1, Wang MF, Chang HC.(PubMed)
(1193) Milk thistle (Silybum marianum) for the therapy of liver disease by Flora K1, Hahn M, Rosen H, Benner K.(PubMed)
(1194) Milk thistle in liver diseases: past, present, future by Abenavoli L1, Capasso R, Milic N, Capasso F.(PubMed)
(1195) Silymarin inhibits cell cycle progression and mTOR activity in activated human T cells: therapeutic implications for autoimmune diseases. by Gharagozloo M1, Javid EN, Rezaei A, Mousavizadeh K.(PubMed)
(1196) Silibinin reverses drug resistance in human small-cell lung carcinoma cells by Sadava D1, Kane SE.(PubMed)
(1197) Silibinin inhibits accumulation of myeloid-derived suppressor cells and tumor growth of murine breast cancer. by Forghani P1, Khorramizadeh MR, Waller EK.(PubMed)
(1198) Silymarin induces cell cycle arrest and apoptosis in ovarian cancer cells. by Fan L1, Ma Y1, Liu Y1, Zheng D2, Huang G3.(PubMed)
(1199) Immunosuppressive effect of silymarin on mitogen-activated protein kinase signalling pathway: the impact on T cell proliferation and cytokine production by Gharagozloo M1, Jafari S, Esmaeil N, Javid EN, Bagherpour B, Rezaei A.(PubMed)
(1200) Analysis of silibinin in rat plasma and bile for hepatobiliary excretion and oral bioavailability application by Wu JW1, Lin LC, Hung SC, Chi CW, Tsai TH.(PubMed)
(1201) Possible involvement of nitric oxide in antidepressant-like effect of silymarin in male mice. by Khoshnoodi M1, Fakhraei N, Dehpour AR.(PubMed)
(1202) Effects and tolerance of silymarin (milk thistle) in chronic hepatitis C virus infection patients: a meta-analysis of randomized controlled trials by Yang Z1, Zhuang L2, Lu Y1, Xu Q1, Chen X1.(PubMed)
(1203) Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial by Fried MW1, Navarro VJ, Afdhal N, Belle SH, Wahed AS, Hawke RL, Doo E, Meyers CM, Reddy KR; Silymarin in NASH and C Hepatitis (SyNCH) Study Group.(PubMed)
(1204) Shui fei ji(Complementary and Alternative Healing University)
(1205) The clinical utility of milk thistle (Silybum marianum) in cirrhosis of the liver by Boerth J1, Strong KM.(PubMed)
(1206) Immunosuppressive effect of silymarin on mitogen-activated protein kinase signalling pathway: the impact on T cell proliferation and cytokine production by Gharagozloo M1, Jafari S, Esmaeil N, Javid EN, Bagherpour B, Rezaei A.(PubMed)
(1207) Systematic review of the efficacy of herbal galactogogues by Mortel M1, Mehta SD.(PubMed)
(1208) Effect of reinforcing kidney-essence, removing phlegm, and promoting mental therapy on treating Alzheimer'sdisease. by Liu P1, Kong M, Liu S, Chen G, Wang P.(PubMed)
(1209) Effects of Chinese medicine for tonifying the kidney and resolving phlegm and blood stasis in treating patients with amnestic mild cognitive impairment: a randomized, double-blind and parallel-controlled trial by Miao YC1, Tian JZ, Shi J, Mao M.(PubMed)
(1210) Effects of acupuncture on Chinese medicine syndromes of vascular dementia. by Shi GX1, Liu CZ, Guan W, Wang ZK, Wang L, Xiao C, Li ZG, Li QQ, Wang LP.(PubMed)
(1211) Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: a cross-validation study against amyloid positron emission tomography by Palmqvist S1, Zetterberg H2, Blennow K2, Vestberg S3, Andreasson U2, Brooks DJ4, Owenius R5, Hägerström D6, Wollmer P7, Minthon L8, Hansson O8.(PubMed)
(1212) Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease by Lautner R1, Palmqvist S2, Mattsson N3, Andreasson U1, Wallin A1, Pålsson E1, Jakobsson J1, Herukka SK4, Owenius R5, Olsson B1, Hampel H6, Rujescu D7,Ewers M8, Landén M9, Minthon L2, Blennow K1, Zetterberg H10, Hansson O2; Alzheimer’s Disease Neuroimaging Initiative.(PubMed)
(1213) Immunity factors for two related tRNAGln targeting killer toxins distinguish cognate and non-cognate toxic subunits by Klassen R1, Kast A, Wünsche G, Paluszynski JP, Wemhoff S, Meinhardt, F. (PubMed)
(1214) Non structural protein of avian influenza A (H11N1) virus is a weaker suppressor of immune responses but capable of inducing apoptosis in host cells. by Mukherjee S1, Majumdar S, Vipat VC, Mishra AC, Chakrabarti AK.(PubMed)
(1215) The anorexia of aging in humans by Hays NP1, Roberts SB.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia Induced by Blood Stasis -TCM Herbal Polygonum multiflorum (He shou wu)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
B.4. Dementia due to Blood Stasis
According to Chinese medical literaure over 3000 years of history, blood stasis may be caused by spleen qi deficiency, but in most cases, it is due to heart qi deficiency cause of inability in transport nutrients to the body organs and cells, including the brain. Prolong period of malnutrition of brain cells may induce abnormal function of brain's cells in information transmitting or death of neurons, cognitive impairments(844), including learning and memory deficits(842) and changes in brain tissues and behavior patterns(843)(842). Blood statsis induced by cold(1142), emotional disorder(1143), aging(1144),chronic illnesses and consumptive disease(1145), can overload the heart capacity, contributing to long-term hypertension(1146) due to decreased or impeded blood flow(1147) causes of hypo-perfusion in cerebral blood flow or acute focal stroke in memory-related cerebral parenchyma induced progression of cognitive decline(*).
2. Polygonum multiflorum (He shou wu)
He Shu Wu or Ye Jiao Teng or Shu Wu is also known as Fleece flower root or Fo-ti.
a. The prepared herb is astringent with some sweetness, mildly warm
b. The raw herb is bitter, sweet and neutral
used in TCM to treatment of hyperlipemia(1173), neurasthenia(1174), split personality(1174), promoted hair grown(1175) and prevent hair loss(1176) due to aging, skin rash due to inflammation(1177), etc., as it tonifies and benefits the essence and blood, expels toxins, moistens the intestines, etc. by enhancing the (The prepared herb) liver and kidney channels and (The raw herb) liver, heart and large intestine channels(1178).
Phytochemicals
1. Polygoacetophenoside
2. Chrysophanol
3. Emodin
4. Rhein
5. Emodin-6
6. Physcion
7. Chrysophanic acid
8. Anthrone
9. beta-sitosterol
10. 2,3,5,4′-tetrahydroxystibene-2O-b-D-glucoside
11. Quercetin-3-O-galactoside
12. Querctin-3-O-arabinoside
13. Lecithin
14. Etc.
2.1. In Alzheimer's disease
Polygonum multiflorum extract, significantly improved AD patients with total effective rate of 93.33% in clinical trial, according to Third XiangyaHospital(1179). In rat model, induced Alzheimer's disease by injecting Abeta 1-40, the herb exhibited improvement of learning and memory ability, through expression of the fluidity of mitochondria membrane and the activity of mitochondrial COX(1180) and ameliorated hippocampal synapses count and synaptophysin expression(1181). In cognitive deficits induced by Abeta25-35,Polygonum multiflorum water extract, also significantly ameliorated the cognitive deficits, probably due to its antioxidant properties(1182).
2.2. In Parkinson disease
Strong evidences suggested that agricultural chemicals and environment toxins, such as dithiocarbamate fungicides, impacted dopamine systems has shown to associate to the development of Parkinson's disease,(1184)(1185). In nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice model, ethanol-soluble PME (PME-I) water extracts from Polygonum multiflorum, improved locomotor activity, motor incoordination, and declines of dopamine level, probably through phytochemicals, in the ethanol-soluble fraction(1183).
2.3. In neuroprotective effects
In focal cerebral ischemia mice, hexane extracts of Polygonum multiflorum, exhibited its neuroprotective effects though significantly decreased infarct size and improved neurological and motor function, (1186) and attenuated glutamate-induced neurotoxicity in a concentration-dependent manner and prevented apoptosis of cortical neurons(1187), in HT22 hippocampal cells(1188), probably through it antioxidant activity. According to Xuanwu Hospital of Capital Medical University, 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) extract from Polygonum multiflorum, also improved mitochondrial function, decreased oxidative stress and inhibited apoptosis against induced cytotoxicity in human dopaminergic neuroblastoma SH-SY5Y cells(1188).
2.4. In learning and memory
Dietary supplementation with either ethanol or water extracts of Polygonummultiflorum have shown to reduce brain pathological changes and promote learning and memory ability(1191)(1192). In male Sprague-Dawley rats, injected with beta amyloid (Aβ), tetrahydroxystilbene glucoside, an active chemical constituent of extract from Polygonum multiflorum, significantly improved the learning and memory, through protecting synaptic structure and function(1189) and learning and/or memory ability of aged rats by increasedBeta-secretase 1 (BACE1), a beta-site amyloid precursor protein cleaving enzyme 1 and decreased ADAM10 (metallopeptidase domain 10), a protein associated to the development of Alzheimer's disease(1190).
B.5. According to TCM philosophy, dementia is also to be induced by the combination/or of Kidney essence vacuity and toxin (turbid phlegm).
C.5.1. Dementia due to toxins accumulation
Toxins accumulation in internal organs disturbed the balance of immunity(1213)(1214) may cause impairment of food intake regulation(1215), exhibition of phlegm(1208)(1208)(1210), retention of fluid(1211)(1212) and blood statsis(1209) induced early the onset of dementia, in aging population with depletion of kidney-essence(1208)(1209), according to traditional Chinese medicine.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(842) Folate deficiency in rat pups during weaning causes learning and memory deficits. by Berrocal-Zaragoza MI1, Sequeira JM1, Murphy MM2, Fernandez-Ballart JD2, Abdel Baki SG3, Bergold PJ3, Quadros EV1.(PubMed)
(843) Changes in brain tissue and behavior patterns induced by single short-term fasting in mice. by Hisatomi Y1, Asakura K, Kugino K, Kurokawa M, Asakura T, Nakata K.(PubMed)
(844) Combined low calcium and lack magnesium is a risk factor for motor deficit in mice. by Taniguchi R1, Nakagawasai O, Tan-no K, Yamadera F, Nemoto W, Sato S, Yaoita F, Tadano T.(PubMed)
(1173) [Blood lipid-regulation of stilbene glycoside from polygonum multiflorum].[Article in Chinese] by Gao X1, Hu YJ, Fu LC.(PubMed)
(1174) Polygonum multiflorum extracts improve cognitive performance in senescence accelerated mice by Chan YC1, Wang MF, Chang HC.(PubMed)
(1175) In vivo hair growth-stimulating effect of medicinal plant extract on BALB/c nude mice by Begum S1, Gu LJ, Lee MR, Li Z, Li JJ, Hossain MJ, Wang YB, Sung CK.(PubMed)
(1176) [Impact of 2, 3-dihydrocyclopentacoumarins to growth of transgenic hairy roots of Polygonum multiflorum and accumulation of stilbene glucosides].[Article in Chinese] by Liu L1, Zhou L, Zhang M, Yu R.(PubMed)
(1177) [Treatment of chronic primary glomerulopathy patients of Shen deficiency and dampness heat syndrome by yishen qingli granule combined low-dose Tripterygium wilfordii multiglycoside tablet: a clinical efficacy observation].[Article in Chinese] by Sheng MX1, Sun W2, Xing CY3, Yuan FH4, Tang SF5, Xiong PH6, Ma JP7, Zhou D2, Gao K2, Jiang Y2, Chen JH2, Mao HJ3, Mou J4, Luo YZ5, Wei MG6, Liu CX7.(PubMed)
(1178) HE SHOU WU (Complementary and Alternative Healing University)
(1179) [Effect of compound Polygonum multiflorum extract on Alzheimer's disease].[Article in Chinese] by Chen L1, Huang J, Xue L.(PubMed)
(1180) Effect of polygonum multiflorum on the fluidity of the mitochondria membrane and activity of COX in the hippocampus of rats with Abeta 1-40-induced Alzheimer's disease. by Hou DR1, Wang Y, Xue L, Tian Y, Chen K, Song Z, Yang QD.(PubMed)
(1181) Changes in hippocampal synapses and learning-memory abilities in age-increasing rats and effects of tetrahydroxystilbene glucoside in aged rats by Wang R1, Tang Y, Feng B, Ye C, Fang L, Zhang L, Li L.(PubMed)
(1182) Protective effect of Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 induced cognitive deficits in mice by Um MY1, Choi WH, Aan JY, Kim SR, Ha TY.(PubMed)
(1183) Neuroprotective effects of Polygonum multiflorum on nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice by Li X1, Matsumoto K, Murakami Y, Tezuka Y, Wu Y, Kadota S.(PubMed)
(1184) The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease by Thiruchelvam M1, Richfield EK, Baggs RB, Tank AW, Cory-Slechta DA(PubMed)
(1185) Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models? by Cicchetti F1, Drouin-Ouellet J, Gross RE.(PubMed)
(1186) Hexane extracts of Polygonum multiflorum improve tissue and functional outcome following focal cerebral ischemia in mice by Lee SV1, Choi KH1, Choi YW2, Hong JW1, Baek JU1, Choi BT1, Shin HK1.(PubMed)
(1187) Hexane extract from Polygonum multiflorum attenuates glutamate-induced apoptosis in primary cultured cortical neurons by Jang JY1, Kim HN, Kim YR, Choi YW, Choi YH, Lee JH, Shin HK, Choi BT.(PubMed)
(1188) Tetrahydroxystilbene glucoside protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity by Sun FL1, Zhang L, Zhang RY, Li L.(PubMed)
(1189) Tetrahydroxystilbene glucoside improves the learning and memory of amyloid-β(₁₋₄₂)-injected rats and may be connected to synaptic changes in the hippocampus by Zhou L1, Hou Y, Yang Q, Du X, Li M, Yuan M, Zhou Z.(PubMed)
(1190) Tetrahydroxystilbene glucoside improves learning and (or) memory ability of aged rats and may be connected to the APP pathway by Hou Y1, Yang Q, Zhou L, Du X, Li M, Yuan M, Zhou Z, Li Z.(PubMed)
(1191) Beneficial effects of different Polygonum multiflorum Thunb. extracts on memory and hippocampus morphology by Chan YC1, Cheng FC, Wang MF.(PubMed)
(1192) Polygonum multiflorum extracts improve cognitive performance in senescence accelerated mice. by Chan YC1, Wang MF, Chang HC.(PubMed)
(1193) Milk thistle (Silybum marianum) for the therapy of liver disease by Flora K1, Hahn M, Rosen H, Benner K.(PubMed)
(1194) Milk thistle in liver diseases: past, present, future by Abenavoli L1, Capasso R, Milic N, Capasso F.(PubMed)
(1195) Silymarin inhibits cell cycle progression and mTOR activity in activated human T cells: therapeutic implications for autoimmune diseases. by Gharagozloo M1, Javid EN, Rezaei A, Mousavizadeh K.(PubMed)
(1196) Silibinin reverses drug resistance in human small-cell lung carcinoma cells by Sadava D1, Kane SE.(PubMed)
(1197) Silibinin inhibits accumulation of myeloid-derived suppressor cells and tumor growth of murine breast cancer. by Forghani P1, Khorramizadeh MR, Waller EK.(PubMed)
(1198) Silymarin induces cell cycle arrest and apoptosis in ovarian cancer cells. by Fan L1, Ma Y1, Liu Y1, Zheng D2, Huang G3.(PubMed)
(1199) Immunosuppressive effect of silymarin on mitogen-activated protein kinase signalling pathway: the impact on T cell proliferation and cytokine production by Gharagozloo M1, Jafari S, Esmaeil N, Javid EN, Bagherpour B, Rezaei A.(PubMed)
(1200) Analysis of silibinin in rat plasma and bile for hepatobiliary excretion and oral bioavailability application by Wu JW1, Lin LC, Hung SC, Chi CW, Tsai TH.(PubMed)
(1201) Possible involvement of nitric oxide in antidepressant-like effect of silymarin in male mice. by Khoshnoodi M1, Fakhraei N, Dehpour AR.(PubMed)
(1202) Effects and tolerance of silymarin (milk thistle) in chronic hepatitis C virus infection patients: a meta-analysis of randomized controlled trials by Yang Z1, Zhuang L2, Lu Y1, Xu Q1, Chen X1.(PubMed)
(1203) Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial by Fried MW1, Navarro VJ, Afdhal N, Belle SH, Wahed AS, Hawke RL, Doo E, Meyers CM, Reddy KR; Silymarin in NASH and C Hepatitis (SyNCH) Study Group.(PubMed)
(1204) Shui fei ji(Complementary and Alternative Healing University)
(1205) The clinical utility of milk thistle (Silybum marianum) in cirrhosis of the liver by Boerth J1, Strong KM.(PubMed)
(1206) Immunosuppressive effect of silymarin on mitogen-activated protein kinase signalling pathway: the impact on T cell proliferation and cytokine production by Gharagozloo M1, Jafari S, Esmaeil N, Javid EN, Bagherpour B, Rezaei A.(PubMed)
(1207) Systematic review of the efficacy of herbal galactogogues by Mortel M1, Mehta SD.(PubMed)
(1208) Effect of reinforcing kidney-essence, removing phlegm, and promoting mental therapy on treating Alzheimer'sdisease. by Liu P1, Kong M, Liu S, Chen G, Wang P.(PubMed)
(1209) Effects of Chinese medicine for tonifying the kidney and resolving phlegm and blood stasis in treating patients with amnestic mild cognitive impairment: a randomized, double-blind and parallel-controlled trial by Miao YC1, Tian JZ, Shi J, Mao M.(PubMed)
(1210) Effects of acupuncture on Chinese medicine syndromes of vascular dementia. by Shi GX1, Liu CZ, Guan W, Wang ZK, Wang L, Xiao C, Li ZG, Li QQ, Wang LP.(PubMed)
(1211) Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: a cross-validation study against amyloid positron emission tomography by Palmqvist S1, Zetterberg H2, Blennow K2, Vestberg S3, Andreasson U2, Brooks DJ4, Owenius R5, Hägerström D6, Wollmer P7, Minthon L8, Hansson O8.(PubMed)
(1212) Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease by Lautner R1, Palmqvist S2, Mattsson N3, Andreasson U1, Wallin A1, Pålsson E1, Jakobsson J1, Herukka SK4, Owenius R5, Olsson B1, Hampel H6, Rujescu D7,Ewers M8, Landén M9, Minthon L2, Blennow K1, Zetterberg H10, Hansson O2; Alzheimer’s Disease Neuroimaging Initiative.(PubMed)
(1213) Immunity factors for two related tRNAGln targeting killer toxins distinguish cognate and non-cognate toxic subunits by Klassen R1, Kast A, Wünsche G, Paluszynski JP, Wemhoff S, Meinhardt, F. (PubMed)
(1214) Non structural protein of avian influenza A (H11N1) virus is a weaker suppressor of immune responses but capable of inducing apoptosis in host cells. by Mukherjee S1, Majumdar S, Vipat VC, Mishra AC, Chakrabarti AK.(PubMed)
(1215) The anorexia of aging in humans by Hays NP1, Roberts SB.(PubMed)
Sunday 19 February 2017
The holistic Prevention, Management and Treatment of Dementia due to Blood Stasis -TCM Herbal Safflower (Hong Hua)
Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia Induced by Blood Stasis -TCM Herbal Safflower (Hong Hua)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
B.4. Dementia due to Blood Stasis
According to Chinese medical literaure over 3000 years of history, blood stasis may be caused by spleen qi deficiency, but in most cases, it is due to heart qi deficiency cause of inability in transport nutrients to the body organs and cells, including the brain. Prolong period of malnutrition of brain cells may induce abnormal function of brain's cells in information transmitting or death of neurons, cognitive impairments(844), including learning and memory deficits(842) and changes in brain tissues and behavior patterns(843)(842). Blood statsis induced by cold(1142), emotional disorder(1143), aging(1144),chronic illnesses and consumptive disease(1145), can overload the heart capacity, contributing to long-term hypertension(1146) due to decreased or impeded blood flow(1147) causes of hypo-perfusion in cerebral blood flow or acute focal stroke in memory-related cerebral parenchyma induced progression of cognitive decline(*).
1. Wolfberry (Gou qi)
Gou Qi, the sweet and neutral herb is also known as wolfberry, used in TCM as anti cancers(1148)(1149), antioxidative(1150)(1151) and anti aging(1156)(1157) agent and to treat back, leg, and stomach pain(1152), hypopigmentation(1154), improve vision(1153)(1154), diabetes(1155), premature aging(1156), enhance immune system(1157), lower blood lipids(1158), elevate level of testosterone(1159), simulate estrogen and anti estrogen effect through different estrogen receptor mechanisms(1160) etc., as it nourishes and tonifies Liver and Kidneys, moistens the Lungs, etc., by enhancing the functions of liver, lung and kidney channels(1161).
Phytochemicals
1. Betaine
2. β-sitosterol
3. Linoleic acid
4. Physalien
5. Cryptoxanthin
6. Atropine
7. Hyoscyamine
8. Scopoletin
9. Amino acids
10. Physalein
11. Zeaxanthin
12. Dipalmitate
13. Carotene
14. Etc.
1.1. In Alzheimer's disease(AD)
Elevated plasma homocysteine (Hcy) levels have shown to associate to increased the risk of Alzheime's disease (AD), epidemiologically and clinically. Polysaccharides, phytochemicals derived from wolfberry (LBA) not only inhibited Abeta accumulation but also reduced risk of other factors induced AD(1162). According to the University of Hong Kong, the chemical olysaccharides, also ameliorated glutamate excitotoxicity involved in many neurodegenerative diseases including Alzheimer's disease (AD)(1163). The herbal alkaline extract was found to exhibit neuroprotection, through inhibiting Abeta-peptides induced apoptosis and neuronal cell death(1164).
1.2. In neuroprotective effects
Lycium barbarum polysaccharide (LBP), on focal cerebral ischemic injury in mice model, inhibited neuronal morphological damage and attenuated the neuronal apoptosis through mitochondrial apoptosis pathway(1165). In ischemia-reperfusion-induced damage, chemical Lycium barbarum polysaccharides (LBP), reduced apoptosis and decreasednumber of viable cells in the ganglion cell layer (GCL) and inner nuclear layer (INL), through its antioxidant activity(1166), In PC12 cell, Lycium arbarum extracts inhibited neurotoxin induced Parkinson's disease-like syndrome, through increased intracellular Ca (2+) level and significantly cell viability and cellular ATP levels(1167).
1.3. In cognitive impairment
In prenatal stress-induced cognitive impairment of offspring rats, Lyciumbarbarum showed to inhibit brain oxidative mitochondrial damage andcognitive dysfunction, through its scavenged hydroxyl and superoxide radicals(1168). Kyung-Ok-Ko (KOK), a traditional herbal prescription, containing Lycium, showed to enhance neuroprotective effects in attenuation of memory impairment, probably through its anti-inflammatory activities(1169).
1.4. In learning and memory
Lycium barbarum polysaccharides, scopolamine (SCO-induced cognitive and memory deficits in rats model, ameliorated and suppressed oxidative stress in hippocampus, and neurons apoptosis(1170). On transgenic mouse model of Alzheimer's disease, Gou qi extracts at 10 mg/kg improved the performance of the learning and the memory in rieval phases of tested models, through reduced levels of Aβ(1-42) in hippocampal tissue(1171). According toKyung Hee University, Lycium chinense fruit, in trimethyltin (TMT)-induced neuronal and cognitive impairment rats model, improved learning and memory deficit in impaired learning and memory scores(1172).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(842) Folate deficiency in rat pups during weaning causes learning and memory deficits. by Berrocal-Zaragoza MI1, Sequeira JM1, Murphy MM2, Fernandez-Ballart JD2, Abdel Baki SG3, Bergold PJ3, Quadros EV1.(PubMed)
(843) Changes in brain tissue and behavior patterns induced by single short-term fasting in mice. by Hisatomi Y1, Asakura K, Kugino K, Kurokawa M, Asakura T, Nakata K.(PubMed)
(844) Combined low calcium and lack magnesium is a risk factor for motor deficit in mice. by Taniguchi R1, Nakagawasai O, Tan-no K, Yamadera F, Nemoto W, Sato S, Yaoita F, Tadano T.(PubMed)
(1142) Network-based biomarkers for cold coagulation blood stasis syndrome and the therapeutic effects of shaofu zhuyu decoction in rats by Su S1, Duan J, Cui W, Shang E, Liu P, Bai G, Guo S, Qian D, Tang Y.(PubMed)
(1143) Blood, Blood Stasis, and Blood Path Disorders by Heiner Fruehauf(Classical Chinese medicine)
(1144) Aging & Blood Stasis: A New Tcm Approach to Geriatrics = Shuai Lao Ho Yu Hsueh
by Te-Hsin Yen, Te-Hsin Yen(Good reads)
(1145) A Look at Blood Stasis by Ronald Koh DVM, MS, CVA, CVCH, CVFT. FL USA(Chi Institute)
(1146) Constructing protein-protein interaction network of hypertension with blood stasis syndrome via digital gene expression sequencing and database mining by Lian YH1, Fang MX1, Chen LG2.(PubMed)
(1147) Blood stasis syndrome of coronary heart disease: A perspective of modern medicine. by Yu G1, Wang J.(PubMed)
(1148) Characterization of Lycium barbarum polysaccharide and its effect on human hepatoma cells. by Zhang M1, Tang X, Wang F, Zhang Q, Zhang Z.(PubMed)
(1149) [Inhibition the growth of human leukemia cells by Lycium barbarum polysaccharide].[Article in Chinese] by Gan L1, Wang J, Zhang S.(PubMed)
(1150) Supercritical fluid extract of Lycium chinense Miller root inhibition of melanin production and its potential mechanisms of action. by Huang HC, Huang WY, Tsai TC, Hsieh WY, Ko WP, Chang KJ, Chang TM1.(PubMed)
(1151) Three New Dimers and Two Monomers of Phenolic Amides from the Fruits of Lycium barbarum and Their Antioxidant Activities. by Gao K1, Ma D, Cheng Y, Tian X, Lu Y, Du X, Tang H, Chen J.(PubMed)
(1152) Anti-inflammatory effect of Lycium Fruit water extract in lipopolysaccharide-stimulated RAW 264.7 macrophage cells. by Oh YC1, Cho WK, Im GY, Jeong YH, Hwang YH, Liang C, Ma JY.(PubMed)
(1153) Reversal of the Caspase-Dependent Apoptotic Cytotoxicity Pathway by Taurine from Lycium barbarum (Goji Berry) in Human Retinal Pigment Epithelial Cells: Potential Benefit in Diabetic Retinopathy. by Song MK1, Roufogalis BD, Huang TH.(PubMed)(1154) Goji berry effects on macular characteristics and plasma antioxidant levels. by Bucheli P1, Vidal K, Shen L, Gu Z, Zhang C, Miller LE, Wang J.(PubMed)
(1155) Practical Application of Antidiabetic Efficacy of Lycium barbarum Polysaccharide in Patients with Type 2 Diabetes by Cai H, Liu F, Zuo P, Huang G, Song Z, Wang T, Lu H, Guo F, Han C, Sun G1.(PubMed)
(1156) wolfberry aging (PubMed)
(1157) An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides. by Cheng J1, Zhou ZW2, Sheng HP3, He LJ4, Fan XW5, He ZX6, Sun T7, Zhang X8, Zhao RJ9, Gu L10, Cao C2, Zhou SF11.(PubMed)
(1158) Anti-obesity and hypolipidemic effects of Lycium chinense leaf powder in obese rats. by Kang MH1, Park WJ, Choi MK.(PubMed)
(1159) Antagonistic effects of Lycium barbarum polysaccharides on the impaired reproductive system of male rats induced by local subchronic exposure to 60Co-γ irradiation by Luo Q1, Cui X, Yan J, Yang M, Liu J, Jiang Y, Li J, Zhou Y.(PubMed)
(1160) Lycium barbarum inhibits growth of estrogen receptor positive human breast cancer cells by favorably altering estradiol metabolism. by Li G1, Sepkovic DW, Bradlow HL, Telang NT, Wong GY.(PubMed)
(1161) Qi zi(Complementary and Alternative Healing University)
(1162) Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons. by Ho YS1, Yu MS, Yang XF, So KF, Yuen WH, Chang RC.(PubMed)
(1163) Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons by Ho YS1, Yu MS, Yik SY, So KF, Yuen WH, Chang RC.(PubMed)
(1164) Characterizing the neuroprotective effects of alkaline extract of Lycium barbarum on beta-amyloid peptide neurotoxicity. by Ho YS1, Yu MS, Lai CS, So KF, Yuen WH, Chang RC.(PubMed)
(1165) Lycium barbarum polysaccharide prevents focal cerebral ischemic injury by inhibiting neuronal apoptosis in mice by Wang T1, Li Y2, Wang Y1, Zhou R1, Ma L3, Hao Y1, Jin S1, Du J1, Zhao C4, Sun T3, Yu J5.(PubMed)
(1166) Activation of the Nrf2/HO-1 antioxidant pathway contributes to the protective effects of Lycium barbarum polysaccharides in the rodent retina after ischemia-reperfusion-induced damage by He M1, Pan H1, Chang RC2, So KF3, Brecha NC4, Pu M1.(PubMed)
(1167) Neuroprotective effects of Lycium chinense Miller against rotenone-induced neurotoxicity in PC12 cells by Im AR1, Kim YH, Uddin MR, Chae S, Lee HW, Kim YS, Lee MY.(PubMed)
(1168) A milk-based wolfberry preparation prevents prenatal stress-induced cognitive impairment of offspring rats, and inhibits oxidative damage and mitochondrial dysfunction in vitro by Feng Z1, Jia H, Li X, Bai Z, Liu Z, Sun L, Zhu Z, Bucheli P, Ballèvre O, Wang J, Liu J.(PubMed)
(1169) Neuroprotective effects of a traditional herbal prescription on transient cerebral global ischemia in gerbils by Cai M1, Shin BY, Kim DH, Kim JM, Park SJ, Park CS, Won do H, Hong ND, Kang DH, Yutaka Y, Ryu JH.(PubMed)
(1170) Lycium barbarum polysaccharides prevent memory and neurogenesis impairments in scopolamine-treated rats by Chen W1, Cheng X2, Chen J3, Yi X2, Nie D4, Sun X5, Qin J2, Tian M2, Jin G2, Zhang X2.(PubMed)
(1171) The effects of Gouqi extracts on Morris maze learning in the APP/PS1 double transgenic mouse model of Alzheimer's disease by Zhang Q1, DU X, Xu Y, Dang L, Xiang L, Zhang J.(PubMed)
(1172) Neuroprotective Effect of Lucium chinense Fruit on Trimethyltin-Induced Learning and Memory Deficits in the Rats by Park HJ1, Shim HS, Choi WK, Kim KS, Bae H, Shim I.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Dementia
Dementia is defined as neuro degeneration syndrome among elder, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement over 47 millions
of worldwide population, mostly in the West. The evaluation of the syndrome by holistic medicine has been lacking, especially through conventional medicine research and studies.
TCM Treatment of Dementia Induced by Blood Stasis -TCM Herbal Safflower (Hong Hua)
Based on Chinese ancient medical records, causes of dementia are the results of (*)
B.4. Dementia due to Blood Stasis
According to Chinese medical literaure over 3000 years of history, blood stasis may be caused by spleen qi deficiency, but in most cases, it is due to heart qi deficiency cause of inability in transport nutrients to the body organs and cells, including the brain. Prolong period of malnutrition of brain cells may induce abnormal function of brain's cells in information transmitting or death of neurons, cognitive impairments(844), including learning and memory deficits(842) and changes in brain tissues and behavior patterns(843)(842). Blood statsis induced by cold(1142), emotional disorder(1143), aging(1144),chronic illnesses and consumptive disease(1145), can overload the heart capacity, contributing to long-term hypertension(1146) due to decreased or impeded blood flow(1147) causes of hypo-perfusion in cerebral blood flow or acute focal stroke in memory-related cerebral parenchyma induced progression of cognitive decline(*).
1. Wolfberry (Gou qi)
Gou Qi, the sweet and neutral herb is also known as wolfberry, used in TCM as anti cancers(1148)(1149), antioxidative(1150)(1151) and anti aging(1156)(1157) agent and to treat back, leg, and stomach pain(1152), hypopigmentation(1154), improve vision(1153)(1154), diabetes(1155), premature aging(1156), enhance immune system(1157), lower blood lipids(1158), elevate level of testosterone(1159), simulate estrogen and anti estrogen effect through different estrogen receptor mechanisms(1160) etc., as it nourishes and tonifies Liver and Kidneys, moistens the Lungs, etc., by enhancing the functions of liver, lung and kidney channels(1161).
Phytochemicals
1. Betaine
2. β-sitosterol
3. Linoleic acid
4. Physalien
5. Cryptoxanthin
6. Atropine
7. Hyoscyamine
8. Scopoletin
9. Amino acids
10. Physalein
11. Zeaxanthin
12. Dipalmitate
13. Carotene
14. Etc.
1.1. In Alzheimer's disease(AD)
Elevated plasma homocysteine (Hcy) levels have shown to associate to increased the risk of Alzheime's disease (AD), epidemiologically and clinically. Polysaccharides, phytochemicals derived from wolfberry (LBA) not only inhibited Abeta accumulation but also reduced risk of other factors induced AD(1162). According to the University of Hong Kong, the chemical olysaccharides, also ameliorated glutamate excitotoxicity involved in many neurodegenerative diseases including Alzheimer's disease (AD)(1163). The herbal alkaline extract was found to exhibit neuroprotection, through inhibiting Abeta-peptides induced apoptosis and neuronal cell death(1164).
1.2. In neuroprotective effects
Lycium barbarum polysaccharide (LBP), on focal cerebral ischemic injury in mice model, inhibited neuronal morphological damage and attenuated the neuronal apoptosis through mitochondrial apoptosis pathway(1165). In ischemia-reperfusion-induced damage, chemical Lycium barbarum polysaccharides (LBP), reduced apoptosis and decreasednumber of viable cells in the ganglion cell layer (GCL) and inner nuclear layer (INL), through its antioxidant activity(1166), In PC12 cell, Lycium arbarum extracts inhibited neurotoxin induced Parkinson's disease-like syndrome, through increased intracellular Ca (2+) level and significantly cell viability and cellular ATP levels(1167).
1.3. In cognitive impairment
In prenatal stress-induced cognitive impairment of offspring rats, Lyciumbarbarum showed to inhibit brain oxidative mitochondrial damage andcognitive dysfunction, through its scavenged hydroxyl and superoxide radicals(1168). Kyung-Ok-Ko (KOK), a traditional herbal prescription, containing Lycium, showed to enhance neuroprotective effects in attenuation of memory impairment, probably through its anti-inflammatory activities(1169).
1.4. In learning and memory
Lycium barbarum polysaccharides, scopolamine (SCO-induced cognitive and memory deficits in rats model, ameliorated and suppressed oxidative stress in hippocampus, and neurons apoptosis(1170). On transgenic mouse model of Alzheimer's disease, Gou qi extracts at 10 mg/kg improved the performance of the learning and the memory in rieval phases of tested models, through reduced levels of Aβ(1-42) in hippocampal tissue(1171). According toKyung Hee University, Lycium chinense fruit, in trimethyltin (TMT)-induced neuronal and cognitive impairment rats model, improved learning and memory deficit in impaired learning and memory scores(1172).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
References
(842) Folate deficiency in rat pups during weaning causes learning and memory deficits. by Berrocal-Zaragoza MI1, Sequeira JM1, Murphy MM2, Fernandez-Ballart JD2, Abdel Baki SG3, Bergold PJ3, Quadros EV1.(PubMed)
(843) Changes in brain tissue and behavior patterns induced by single short-term fasting in mice. by Hisatomi Y1, Asakura K, Kugino K, Kurokawa M, Asakura T, Nakata K.(PubMed)
(844) Combined low calcium and lack magnesium is a risk factor for motor deficit in mice. by Taniguchi R1, Nakagawasai O, Tan-no K, Yamadera F, Nemoto W, Sato S, Yaoita F, Tadano T.(PubMed)
(1142) Network-based biomarkers for cold coagulation blood stasis syndrome and the therapeutic effects of shaofu zhuyu decoction in rats by Su S1, Duan J, Cui W, Shang E, Liu P, Bai G, Guo S, Qian D, Tang Y.(PubMed)
(1143) Blood, Blood Stasis, and Blood Path Disorders by Heiner Fruehauf(Classical Chinese medicine)
(1144) Aging & Blood Stasis: A New Tcm Approach to Geriatrics = Shuai Lao Ho Yu Hsueh
by Te-Hsin Yen, Te-Hsin Yen(Good reads)
(1145) A Look at Blood Stasis by Ronald Koh DVM, MS, CVA, CVCH, CVFT. FL USA(Chi Institute)
(1146) Constructing protein-protein interaction network of hypertension with blood stasis syndrome via digital gene expression sequencing and database mining by Lian YH1, Fang MX1, Chen LG2.(PubMed)
(1147) Blood stasis syndrome of coronary heart disease: A perspective of modern medicine. by Yu G1, Wang J.(PubMed)
(1148) Characterization of Lycium barbarum polysaccharide and its effect on human hepatoma cells. by Zhang M1, Tang X, Wang F, Zhang Q, Zhang Z.(PubMed)
(1149) [Inhibition the growth of human leukemia cells by Lycium barbarum polysaccharide].[Article in Chinese] by Gan L1, Wang J, Zhang S.(PubMed)
(1150) Supercritical fluid extract of Lycium chinense Miller root inhibition of melanin production and its potential mechanisms of action. by Huang HC, Huang WY, Tsai TC, Hsieh WY, Ko WP, Chang KJ, Chang TM1.(PubMed)
(1151) Three New Dimers and Two Monomers of Phenolic Amides from the Fruits of Lycium barbarum and Their Antioxidant Activities. by Gao K1, Ma D, Cheng Y, Tian X, Lu Y, Du X, Tang H, Chen J.(PubMed)
(1152) Anti-inflammatory effect of Lycium Fruit water extract in lipopolysaccharide-stimulated RAW 264.7 macrophage cells. by Oh YC1, Cho WK, Im GY, Jeong YH, Hwang YH, Liang C, Ma JY.(PubMed)
(1153) Reversal of the Caspase-Dependent Apoptotic Cytotoxicity Pathway by Taurine from Lycium barbarum (Goji Berry) in Human Retinal Pigment Epithelial Cells: Potential Benefit in Diabetic Retinopathy. by Song MK1, Roufogalis BD, Huang TH.(PubMed)(1154) Goji berry effects on macular characteristics and plasma antioxidant levels. by Bucheli P1, Vidal K, Shen L, Gu Z, Zhang C, Miller LE, Wang J.(PubMed)
(1155) Practical Application of Antidiabetic Efficacy of Lycium barbarum Polysaccharide in Patients with Type 2 Diabetes by Cai H, Liu F, Zuo P, Huang G, Song Z, Wang T, Lu H, Guo F, Han C, Sun G1.(PubMed)
(1156) wolfberry aging (PubMed)
(1157) An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides. by Cheng J1, Zhou ZW2, Sheng HP3, He LJ4, Fan XW5, He ZX6, Sun T7, Zhang X8, Zhao RJ9, Gu L10, Cao C2, Zhou SF11.(PubMed)
(1158) Anti-obesity and hypolipidemic effects of Lycium chinense leaf powder in obese rats. by Kang MH1, Park WJ, Choi MK.(PubMed)
(1159) Antagonistic effects of Lycium barbarum polysaccharides on the impaired reproductive system of male rats induced by local subchronic exposure to 60Co-γ irradiation by Luo Q1, Cui X, Yan J, Yang M, Liu J, Jiang Y, Li J, Zhou Y.(PubMed)
(1160) Lycium barbarum inhibits growth of estrogen receptor positive human breast cancer cells by favorably altering estradiol metabolism. by Li G1, Sepkovic DW, Bradlow HL, Telang NT, Wong GY.(PubMed)
(1161) Qi zi(Complementary and Alternative Healing University)
(1162) Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons. by Ho YS1, Yu MS, Yang XF, So KF, Yuen WH, Chang RC.(PubMed)
(1163) Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons by Ho YS1, Yu MS, Yik SY, So KF, Yuen WH, Chang RC.(PubMed)
(1164) Characterizing the neuroprotective effects of alkaline extract of Lycium barbarum on beta-amyloid peptide neurotoxicity. by Ho YS1, Yu MS, Lai CS, So KF, Yuen WH, Chang RC.(PubMed)
(1165) Lycium barbarum polysaccharide prevents focal cerebral ischemic injury by inhibiting neuronal apoptosis in mice by Wang T1, Li Y2, Wang Y1, Zhou R1, Ma L3, Hao Y1, Jin S1, Du J1, Zhao C4, Sun T3, Yu J5.(PubMed)
(1166) Activation of the Nrf2/HO-1 antioxidant pathway contributes to the protective effects of Lycium barbarum polysaccharides in the rodent retina after ischemia-reperfusion-induced damage by He M1, Pan H1, Chang RC2, So KF3, Brecha NC4, Pu M1.(PubMed)
(1167) Neuroprotective effects of Lycium chinense Miller against rotenone-induced neurotoxicity in PC12 cells by Im AR1, Kim YH, Uddin MR, Chae S, Lee HW, Kim YS, Lee MY.(PubMed)
(1168) A milk-based wolfberry preparation prevents prenatal stress-induced cognitive impairment of offspring rats, and inhibits oxidative damage and mitochondrial dysfunction in vitro by Feng Z1, Jia H, Li X, Bai Z, Liu Z, Sun L, Zhu Z, Bucheli P, Ballèvre O, Wang J, Liu J.(PubMed)
(1169) Neuroprotective effects of a traditional herbal prescription on transient cerebral global ischemia in gerbils by Cai M1, Shin BY, Kim DH, Kim JM, Park SJ, Park CS, Won do H, Hong ND, Kang DH, Yutaka Y, Ryu JH.(PubMed)
(1170) Lycium barbarum polysaccharides prevent memory and neurogenesis impairments in scopolamine-treated rats by Chen W1, Cheng X2, Chen J3, Yi X2, Nie D4, Sun X5, Qin J2, Tian M2, Jin G2, Zhang X2.(PubMed)
(1171) The effects of Gouqi extracts on Morris maze learning in the APP/PS1 double transgenic mouse model of Alzheimer's disease by Zhang Q1, DU X, Xu Y, Dang L, Xiang L, Zhang J.(PubMed)
(1172) Neuroprotective Effect of Lucium chinense Fruit on Trimethyltin-Induced Learning and Memory Deficits in the Rats by Park HJ1, Shim HS, Choi WK, Kim KS, Bae H, Shim I.(PubMed)
Subscribe to:
Posts (Atom)