Monday 22 May 2023

The Anti-#BloodGlucoseImpairment Activity of #Antioxidant #SFN Found in #CruciferousVegetables, Scientists Say

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.
In other words, diabetes occurs when cells in the pancreas die off or receptor sites are clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.

Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.

Untreated hyperglycemia has been found to induce ketoacidosis characterized by the symptoms of shortness of breath, breath that smells fruity and gastrointestinal discomforts such as nausea, vomiting, and dry mouth.

The most common forms of diabetes are type 1 and type 2 diabetes.

In contrast to type II diabetes, type 1 diabetes is not associated with dietary intake or an unhealthy lifestyle that can cause an increase in glucose levels in the blood.

According to Diabetes Canada, patients with type 1 diabetes should be aware of the number of insulin injections that are needed per day; the timing of insulin injections, and the dose of insulin that is needed with each injection

Impaired fasting glucose and glucose tolerance are 2 types of prediabetes,

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding a potential compound for the prevention and treatment of diabetes, researchers examined chronic sulforaphane, a potent inducer of antioxidant enzymes present in cruciferous vegetables oral treatment in blood glucose impairment.

On obesity and insulin resistance induced by a highly palatable (HP) diet in male Wistar SFN showed much-lowering glucose tolerance, compared to the HP diet groups.

Furthermore, the group treated with SFN demonstrated a lower level of liver triacylglycerols but no differences in serum lipids, and hepatic and kidney markers in both HP and SFN groups.

Moreover, SFN. also decreased the expression of GLUT3 associated with the uptake of glucose into the neuron in the cortex and hypothalamus in the HP diet group.

Collectively, researchers wrote, " SFN at the specific dose was able to accentuate glucose intolerance and may affect GLUT3 expression in the cerebral cortex and hypothalamus".

Taken altogether, cruciferous vegetables processed with a high amount of SFN may be considered functional foods for the prevention of blood glucose impairment, pending the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Chronic sulforaphane oral treatment accentuates blood glucose impairment and may affect GLUT3 expression in the cerebral cortex and hypothalamus of rats fed with a highly palatable diet by Souza CG1, Riboldi BP, Hansen F, Moreira JD, Souza DG, de Assis AM, Brum LM, Perry ML, Souza DO. (PubMed)

hypertension
(1) Fruit and vegetable intake and the risk of hypertension in middle-aged and older women by Lu Wang, MD, PhD, JoAnn E. Manson, MD, DrPH, J. Michael Gaziano, MD, MPH, Julie E. Buring, ScD, and Howard D. Sesso, ScD, MPH. (PubMed)
(2) A Tasty Fruit That is Similar to Those of Clonidine, Guanfacine and Metabolite of Methyldopa for Treatment of Hypertension, With No Side Effects by Kyle J. Norton

#Herbal Fennel Extract Inhibits the Symptoms of #PainfulPrimaryDysmenorrhea, According to Studies

By Kyle J. Norton

Adding a portion of fennel in your daily diet may have a potential and positive effect in reduced pain caused by sensory neurons stimulus in women with primary dysmenorrhea, some scientists suggested.

Antinociceptive activity is an action or process of blocking the painful or injurious stimulus by sensory neurons.

The results of the investigation were carried out by numbers of respectable institutes, including the Babol University of Medical Sciences and Health Services and details of the experiment were published on an online medical library.

Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as a warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

In order to compare the effect of the combination of fennel extract/vitamin E with ibuprofen on the intensity of pain in primary dysmenorrhea among the students of Tabriz city in 2007-2009, researchers of the joint study led by the Kosar Department of Shahid Motahhary Hospital carried out an investigation of 68 students from Medical and Tabriz universities, who were living in the dormitory, suffering from primary dysmenorrhea.

All participants were randomly divided into two groups of 34 students each (the two groups used a combination of fennel extract/vitamin E and ibuprofen cross-over form in the 2 months).

Application of the combination displayed a mean of peak pain intensity in the first, second, third, sixth, and forty-eight hours in the group was significantly lower than the group that had used ibuprofen.

Also, a combination of fennel extract/vitamin E was more effective than ibuprofen in the first hour (P < 0.03) and second hour (P < 0.04), according to the Visual Analogue Scale (VAS) tool for ranking the intensity of the pain.

These results suggested that fennel and vitamin E combination was more efficacy in blocking the neuron in transmitting pain caused by overexpression prostaglandin hormone in the induction of abdominal muscle constriction in comparison to conventional medicine ibuprofen.

Dr. Nasehi M, the lead author, after taking into account other co and confounders said, "Combination of fennel extract/vitamin E is effective on decreasing the intensity of pain of primary dysmenorrhea, and it is advised to those who cannot use chemical drugs".

In a separate study to investigate the effect of fennel used alone on primary dysmenorrhea symptoms and menorrhea duration, 80 female students satisfied the criteria, and guidelines were randomly divided into two groups of intervention (n = 40) and control (n = 40).

The intervention group was given one soft capsule Fennel (30 mg) every 4 hours, 3 days before menstruation till the 5th day and continued for 3 months. The control group received no medication.


According to the result of the experiments, the fennel-treated group exerted a significant decrease in the mean of nausea intensity and weakness from 1.93, and 2.88 after 3 months, in comparison to the control group from 2.37, and 6.65 in the control group.

Also in compared to the control group, the fennel group reduced the duration of a menstrual period after two and three months of use.


Moreover, Fennel treated group demonstrated a strong improvement of quality and feelings of well-being after 1 and 3 months.

Taken together, fennel may be considered as a functional food for the treatment of Primary Dysmenorrhea without inducing adverse effects.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio Science, ISSN 0975-6299.

Sources
(1) The effect of fennel on pain quality, symptoms, and menstrual duration in primary dysmenorrhea by Ghodsi Z1, Asltoghiri M2. (PubMed)
(2) Comparison of the effectiveness of a combination of fennel extract/vitamin E with ibuprofen on the pain intensity in students with primary dysmenorrhea by Nasehi M1, Sehhatie F2, Zamanzadeh V3, Delazar A4, Javadzadeh Y5, Chongheralu BM6.(PubMed)

#Phytochemical #Indicaxanthin Exerts a Strong Vascular Protective Activity Against the Onset of #CHD, Researcher Say

By Kyle J. Norton

Blood vessels formed part of the circulatory system that transports blood throughout the body. Arteries and veins are the types of blood vessels that carry blood away from or toward the heart, respectively.
The 3 main types of blood vessels are arteries that deliver oxygen-rich blood from the heart to the tissues and organs of the body.

Damage of arteries may induce coronary artery disease associated with the narrowing or blockage of the coronary arteries due to plaques accumulated in the arterial wall.

Most cases of coronary artery disease are associated with cholesterol building up on the arterial wall found in patients with hypercholesterolemia.

The veins carry blood toward the heart. Chronic venous insufficiency (CVI) is a common condition associated with a disease of the veins that affects up to 20 percent of adults.

The capillaries or the smallest blood vessels that have been found to induce systemic capillary leak syndrome (SCLS) is a rare acquired disorder.


Vasoprotection is the process to improve the function of the blood vessels, including the use of herbal and natural remedies.

Vascular dysfunction associated with dysfunction of large arteries, the microcirculation, and endothelium have been found to induce a substantial risk of cardiovascular disease.


Vascular inflammation that causes reduced blood flow to the body due to the changes in the blood vessel walls, including thickening, weakening, narrowing, or scarring is also one of the most common cardiovascular risk factors associated with patients with atherosclerosis and hypertension.

Indicaxanthin is a phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains found abundantly in beets, chard, etc.

On finding a potential compound that processes protective vascular effects, researchers examined the effect of Indicaxanthin, a natural chemo-active and chemo-preventive agent anti-inflammatory activity, against oxLDL-induced endothelial dysfunction.

According to the results of human umbilical vein cord cells (HUVEC) induced human oxLDL, pretreatment of indicaxanthin in a range between 5 and 20 μM, showed significant inhibition of oxLDL-induced cytotoxicity in a concentration-dependent manner.

Circulating vascular cell adhesion molecule-1 (VCAM-1), and intercellular adhesion molecule-1 (ICAM-1) to serve as molecular markers of atherosclerosis and predictors of incident CHD were a significant increase and ABCA1gened associated with the regulation of cellular cholesterol was significantly decreased in the human oxLDL group compared to pretreatment group.

In other words, the phytochemical exerted protective vascular effects against the incidence of atherosclerosis caused by ox-LDL through its antioxidants and anti-inflammatory expression.

Based on the findings, researchers said, "indicaxanthin as a novel, dietary phytochemicals, able to exert significant protective vascular effects in vitro, at nutritionally relevant concentrations".

Taken altogether, indicaxanthin may be considered a protective vascular remedy, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Indicaxanthin from Opuntia ficus indica (L. Mill) Inhibits Oxidized LDL-Mediated Human Endothelial Cell Dysfunction through Inhibition of NF-κB Activation by Attanzio A1, Frazzitta A1, Busa' R1, Tesoriere L1, Livrea MA1, Allegra M. (PubMed)

#Healthyfood #Carrots inhibit the Heavy Metals and Chemical Toxicity in the Body, Researchers Find

By Kyle J. Norton

Carrots may have a profound and positive effect on expelling heavy metal and chemical toxins from our body through the gastrointestinal tract, some scientists suggested.
The digestive system, includes the salivary glands, mouth, esophagus, stomach, liver, gallbladder, pancreas, small intestine, colon, and rectum. is a system responsible for extracting the nutrients and fluids from the food intake to provide energy for the body's needs and expelling feces from the body?

Some people with digestive problems may experience symptoms of acid reflux and GERD with burning sensation, gas, bloating, constipation, diarrhea, and indigestion. In serious cases, the condition can also cause gallstones, irritable bowel syndrome, hemorrhoids,...

Some researchers suggested that eating 7 or more servings of fruits and vegetables daily, replacing refined grain products with whole grain products, reducing intake of processed food and red meat, and engaging in daily physical activity are the best to optimize digestive health.

Including vitamin D and calcium in the diet are also helpful.

Carrot, a root vegetable with an orange color is a sub-species of Daucus carota, belonging to the family Apiaceae, native to Asia and Europe.

Concerns about the damage of heavy metal damage to the body, researchers at Northwest A&F University, launched an investigation to examine whether insoluble dietary fiber from carrot pomace effect in exerting the protection of the digestive tract,

Researchers found that using the ultra-micro grinding process, the insoluble dietary fiber exerts far better potential in inhibited levels of glucose-, nitrite-, and lead ion- compared to the raw insoluble dietary fiber.

Truly, the ultra-micro grinding process could significantly decrease the particle size of carrot insoluble dietary fiber and increase its Brunauer-Emmett-Teller surface area from 0.374 to 1.835 m(2) g(-1).
The method also improved the water-holding capacity, swelling capacity and oil-holding capacity increased by 62.09%, 49.25%, and 45.45%, respectively.

These may be the reasons the insoluble dietary fiber from carrot pomace treated with an ultra-micro grinding process displays a significant effect in the protection of the digestive system through absorption of the far greater level of heavy and toxic metals.

The processed application also effectively protects Caco-2 cells from lead ion damage, according to the apoptosis assessment by AO/EB, compared to the raw contents

At the concentration of 10.0 mg, carrot insoluble dietary fiber has no toxicity for Caco-2 cells, the MTT assay showed.

The results of this study highlighted the potential of the ultra-micro grinding process to produce a high-added-value fiber ingredient from carrot residue with the function of protecting the gastrointestinal tract against heavy and toxic chemicals.

Taken together, carrot's insoluble dietary fiber may be used as a functional food in improving digestive function by absorbing heavy and toxic chemicals before causing harm to the body tissue and organs.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Physicochemical properties and intestinal protective effect of ultra-micro ground insoluble dietary fibre from carrot pomace by Ma S1, Ren B, Diao Z, Chen Y, Qiao Q, Liu X(PubMed)

#Antioxidant #Bromelain Inhibits the Onset of Parameters That Cause Cancer, Researchers Say

By Kyle J. Norton

Cancer is a class of chronic and medical conditions caused by the alternation of cell DNA.
Most cases of cancer start in the cells on the surface of the inner lining of specific tissues and organs.

At the early stage due to the very small size of the tumor, most cancers are asymptomatic. However, at the advanced stage, cancer only can induce general symptoms such as gastrointestinal discomfort, unintended weight loss, fatigue, and loss but also lead to specific symptoms, such as localized bleeding and pain, depending on the location of the cancer.

Also, at this stage, primary cancer cells can travel a distance away from the original site to infect other healthy tissues and organs, leading to secondary metastasis through the circulation of blood and fluids.

According to the statistic provided by the American Cancer Society, in the US in 2019, approximately 1,762,450 new cancer cases will be diagnosed and 606,880 deaths are cancer.

Furthermore, in the age perspective, older adults although accounted for only 8% of all cases diagnosed in the US, have a 17% mortality rate compared to other age groups.

The 5 years survival rate is totally depending on the stage of cancer diagnosed. The early diagnosed stage has the highest survival rate compared to other later stages.

Many risk factors such as aging, tobacco, sun exposure, toxic exposure, viruses, and bacteria, use of hormone therapy, family history of cancer, alcohol, poor diet, lack of physical activity, or being overweight have been found to increase the risk of cancer, epidemiologically.

However, most people with some of the aforementioned risk factors have never developed cancer.

Some researchers in the examination of the risk of obesity in risk cancer wrote, "The prevalence of overweight and obesity is increasing worldwide, and the evidence base for a link between obesity and cancer is growing... Recent research has found that as the body mass index increases by 5 kg/m2, cancer mortality increases by 10%".

Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus), has been used in traditional medicine as an inflammatory agent to treat pains, strains, muscle aches, and pains and ease back pain, chronic joint pain, skin diseases, etc.

The research team at the University of Oxford on finding a potential compound for cancer treatment with no side effects examined the bromelain capacity against cancers in past and present studies.

Evidence derived from clinical observations, mouse- and cell-based models suggested that bromelain, a 95%-mixture of proteases acts systemically, affecting multiple cellular and molecular targets.

The most recent study found that bromelain has the capacity to inhibit cell malignancy by modulating the critical pathways associated with cell differentiation.

Other studies suggested the anti-cancer activity of bromelain consists of the direct impact on cancer cells and their microenvironment by modulating immune, inflammatory, and hemostatic systems.

Additionally, in the study to reaffirm the use of bromelain (BL) as an anti-cancer phytotherapeutic agent, researchers examined the Oral administration of bromelain (BL) in anti-cancer drugs encapsulated in Poly(lactic-co-glycolic acid) (PLGA) to formulate nanoparticles (NPs).

NPs enhanced the function of cytotoxicity in the induction of cancer cell death in the significant dose advantage (-7-10 folds) that reduces the IC50 values, compared to free BL.

NPs induced cellular uptake of MCF-7, HeLa, and Caco-2 cells monolayer by several folds compared to free BL.

NPs also modulated the expression of marker proteins associated with apoptosis and cell death and suppression (P53, P21, Bcl2, Bax).

Furthermore, in Swiss albino mice, NPs injection not only reduced the tumor burden of Ehrlich ascites carcinoma (EAC) but also increased their lifespan (160.0 ± 5.8%) compared to free BL.

In other words, NPs enhanced anti-carcinogenic potential through a number of mechanisms, including the generation of reactive oxygen species, induction of apoptosis, and impaired mitochondrial membrane potential.

Taken altogether, bromelain used alone or encapsulated in Poly(lactic-co-glycolic acid) (PLGA) may be considered supplements for the prevention and treatment of cancer, pending the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Bromelain's activity and potential as an anti-cancer agent: Current evidence and perspectives by Chobotova K1, Vernallis AB, Majid FA. (PubMed)
(2) Anti-cancer activity of bromelain nanoparticles by oral administration by Bhatnagar P, Patnaik S, Srivastava AK, Mudiam MK, Shukla Y, Panda AK, Pant AB, Kumar P, Gupta KC. (PubMed)
(3) Obesity and Cancer Risk: Recent Review and Evidence by Karen Basen-Engquist and Maria Chang. (PMC)

Comparing the #Antioxidant Contents of Organic and Conventional Growth #Onion

By Kyle J. Norton

Antioxidants are molecules that inhibit oxidation. In other words, Antioxidants donate or intercept the lone electron in the outermost ring of free radicals before they can cause damage to the protein, lipid, and cell damage.

Free radicals are reactive oxidative species or ROS that are chemically reactive atoms containing oxygen

In other words, ROS includes a number of reactive molecules and free radicals derived from molecular oxygen, including peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen.

Free radicals are unstable molecules. Therefore, in order for them to maintain stability, free radicals must intercept or donate an electron to or from the stable atoms respectively, leading to a domino's effect that can not be stopped until all outermost ring electrons are paired or inhibited by antioxidants.

Long-term overexpression of free radicals compared to antioxidants can result in oxidative stress, a leading cause of protein, lipid and cellular damage.

In a healthy individual, antioxidant enzymes produced by the body are good enough to neutralize the levels of free radicals in the body. However, people with a weakened immune system may need an additional dietary source of antioxidants.

The most common risk factors associated with oxidative stress are antioxidant deficiency in the body caused by demographic, physical, lifestyle, or nutritional factors.


Some researchers suggested people who smoke may be at an increased risk of oxidative stress.

Hydroxyl radical (OH•) is the most common and very dangerous free radical form of the hydroxide ion (OH–). It is produced from the decomposition of hydroperoxides (ROOH) by the reaction of an elevation in energy level above an arbitrary baseline energy state molecular oxygen with water.

The hydroxyl radical is highly reactive and has a very short in vivo half-life of approx. 10−9 s Hydroxyl radical cannot be eliminated by an enzymatic reaction and can damage virtually all types of macromolecules: carbohydrates, nucleic acids (mutations), lipids (lipid peroxidation), and amino acids.

Believe it or not, free radical levels in a moderate amount are necessary to enhance the body functioning, including vascular relaxation.

By balancing the ratio of free radicals and antioxidants may be the best way to avoid the development of chronic illness associated with oxidative stress.


The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

On finding a potential compound that processed significant antioxidants researchers differentiated the antioxidant compounds in the 'Hyskin' and 'Red Baron' onions.

By comparing the levels of antioxidants in conventional and organic growth onion, researchers found that
* Total flavonoids were higher in 'Red Baron' and when onions were grown under organic soil treatment.

* There are no differences among the total anthocyanins, individual flavonols, and individual anthocyanins in both methods of cultivation.

Based on the findings, organically cultivated onion may have a stronger antioxidant activity compared to those of conventional growth due to the higher content of total flavonoids.
Further differentiation of the methods of cultivation, researchers wrote, "Differences were primarily due to different soil management practices used in organic agriculture rather than pesticide/ herbicide application".

Moreover, based on the results of the effect of conventional, organic, and mixed cultivation practices on the content of total phenolics, total flavonoids, and antioxidant activity in the same in two varieties of onion grown over 4 years in a split-plot factorial systems comparison trial, researchers also found that

* Levels of total phenolics and total flavonoids process a significant year-on-year variation.

* Levels of antioxidants were also significantly different between organic and conventional production systems.

* Fully organic onion processed a high antioxidant content compared to those of fully conventional growth


Taken altogether, onion cultivated organically processed higher levels of antioxidants compared to conventional cultivation, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Higher Antioxidant Activity, Total Flavonols, and Specific Quercetin Glucosides in Two Different Onion (Allium cepa L.) Varieties Grown under Organic Production: Results from a 6-Year Field Study by Ren F1,2, Reilly K1, Kerry JP2, Gaffney M1, Hossain M1, Rai DK. (PubMed)
(2) Evaluation of polyphenolic content and antioxidant activity in two onion varieties grown under organic and conventional production systems by Ren F1,2, Reilly K1, Gaffney M1, Kerry JP2, Hossain M1, Rai DK. (PubMed).
(3) Antioxidants - Most Common Types of Free Radicals by Kyle J. Norton

#Herbal #Andrographis in the Promotion of Anti #NonSmallCellLungCancer #NSCLC Activites, Researchers Suggest

By Kyle J. Norton

Andrographis may be used as a possible therapeutic herbal medicine for the prevention and treatment of Lung cancer, a Taiwan study suggested.

Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,...

Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. Most common forms of primary lung cancers are derived from epithelial cells. In the US, Lung cancer is the leading cause of cancer deaths of 158,683 people, including 88,329 men and 70,354 women, according to the 2007 statistic.

According to the National Chung Hsing University, andrographolide, one of the major diterpene lactones found in Andrographis paniculata exhibited anti pulmonary cancer effects in a lung tumor mouse.

Dr. Tung YT, the lead author of the study said, "Andrographolide treatment on the overexpression of VEGF can arrest the cell cycle, which induced pulmonary tumors in transgenic mice".

In non-small-cell lung cancer, intake of andrographolide significantly enhanced the function of HLJ1, a novel tumor suppressor in used as a druggable target for non-small-cell lung cancer (NSCLC).



Furthermore, andrographolide also affected the genes expression involved in the cell cycle, apoptosis and adhesion-related biological signaling, leading to inhibition of the development and progression of non-small cell lung cancer.

Other study insisted that the inhibition of andrographolide on non-small cell lung cancer (NSCLC) A549 cell migration and invasion is also attributed to other mechanisms beside gene expression, such as phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway in regulating the cell cycle, VEGF pathway in regulating of tumor angiogenesis,, etc.


There is no doubt that andrographolide may be a promising new anticancer agent used in suppressed tumor growth and invasion in NSCLC, but more studies are necessary to confirm the validation.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Sources
(1) Therapeutic Potential of Andrographolide Isolated from the Leaves of Andrographis paniculata Nees for Treating Lung Adenocarcinomas by Tung YT1, Chen HL, Tsai HC, Yang SH, Chang YC, Chen CM.(PubMed)
(2) The HLJ1-targeting drug screening identified Chinese herb andrographolide that can suppress tumour growth and invasion in non-small-cell lung cancer by Lai YH1, Yu SL, Chen HY, Wang CC, Chen HW, Chen JJ.(PubMed)
(3) Andrographolide down-regulates hypoxia-inducible factor-1α in human non-small cell lung cancer A549 cells by Lin HH1, Tsai CW, Chou FP, Wang CJ, Hsuan SW, Wang CK, Chen JH.(PubMed)
(4) Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway by Lee YC1, Lin HH, Hsu CH, Wang CJ, Chiang TA, Chen JH(PubMed)