Cruciferous vegetables Inhibit Oral Cancer in Vitro

By Kyle J. Norton

Oral cancer is a medical condition characterized by irregular cell growth in the oral cavity. In the early stage, the abnormal cells only appear in the surface lining of the cavity. However, in the late stage, the infectious cells may travel a distance away from the original site to invade other cells and tissue.

Early diagnosed oral cancer may have a close to 100% recovery.

Most cases of oral cancer begin in the cells on the surface of the inner lining of oral tissue.

However, at the advanced stage, oral cancer cells can travel a distance away to infect other healthy tissue and organs, leading to secondary metastasis.

According to the statistic provided by the American Cancer Society, in 2018, approximately 51,540 people were diagnosed with oral cavity or oropharyngeal cancer. The disease causes the death of an estimated 10,030 people.

The 5-year survival rate of oral cancer is 66%, including all stages.

Family history, smoking, alcohol drinking, infection by the HPV virus, poor hygiene, and genetic preposition are some of the risk factors associated with the disease.

According to the cancer society, the 5 survival rate of oral cancer is about 60% plus without taking into consideration the stage of cancer.

The early symptoms of oral cancer include lip or mouth sores and persistent pain,... Check with a dentist, if you experience the above unexplained or persistent symptoms, particularly, if the sore mouth does not heal in 2 weeks.

Cruciferous vegetables are a group of vegetables, belongings of the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding potential and natural foods for the prevention and treatment of cancer, researchers investigated the effect of sulforaphane, a predominant isothiocyanate in Brassica oleracea, a family of cruciferous vegetables on oral carcinoma cell lines.

According to the tested analysis. sulforaphane showed strong growth inhibition of oral carcinoma cell lines by blocking the cancer cell migration and invasion activities.

Based on the Multiplex protein analysis kits, the impairment of the migration and invasion induced by sulforaphane were attributed to associated with the anti-orchestration in the secretion of metalloprotease levels including MMP-1 and MMP-2.

In other words, sulforaphane demonstrated a therapeutic potency as an inhibitor of metastasis in oral carcinoma cell lines.

Taken altogether, cruciferous vegetables processed abundantly sulforaphane, may be considered functional remedies for the prevention of oral cancer, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Sulforaphane inhibits oral carcinoma cell migration and invasion in vitro by Jee HG1, Lee KE, Kim JB, Shin HK, Youn YK. (PubMed)

Phytochemical Beta-Sitosterol Alleviates the Progression of Fatty Liver in Vivo

By Kyle J. Norton

The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.

The liver also produces cholesterol, a waxy substance that aids digestion, builds cell membranes, and produces vitamin D and steroid hormones.

Liver disease is a class of medical conditions characterized by reducing partly or completely the function of the liver, including liver failure.

A fatty liver is a liver condition associated with the accumulation of excess fat in the liver.

There are two main types of fatty liver disease:
* Nonalcoholic fatty liver disease is a medical condition characterized by fat accumulated in the liver tissue other than excessive consumption of alcohol.
According to the American liver foundation, Nonalcoholic Fatty Liver Disease is one of the most common causes of liver disease, and approximately 30% (100 million) individuals in the United States are estimated to have nonalcoholic fatty liver disease.

The causes of Nonalcoholic Fatty Liver Disease are unknown. Also, as of today researchers do not understand why some people are susceptible to liver fat accumulation while others are not.

The disease can be classified into the types of non-inflammatory fatty liver (NAFL) and inflammatory nonalcoholic steatohepatitis (NASH) and acute fatty liver of pregnancy (AFLP), a relatively rare disorder that happens only during pregnancy.

* Alcoholic fatty liver diseases is a condition caused by lifelong heavy alcohol use.

In other words, substances found in alcohol damage liver cells, promote inflammation and weaken your body's natural defenses. More precisely, the more alcohol that you drink, the more you damage your liver.

Alcoholic fatty liver disease is the earliest stage of alcohol-related liver disease.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

In finding a potential phytochemical for the prevention and treatment of liver diseases, researchers elucidated the effects of stigmasterol and β-sitosterol on a high-fat Western diet (HFWD)-induced nonalcoholic fatty liver disease (NAFLD).

According to the results after 33 weeks of treatment* stigmasterol and β-sitosterol were effective in protecting the liver against HFWD-induced NAFLD.

* The parameters that contributed to the onset of NAFLD are triacylglycerols (TGs), phosphatidylcholines, cholesteryl esters, diacylglycerols, and free fatty acids (FFAs).

* The efficacy of stigmasterol and β-sitosterol in the alleviation of NAFLD was mainly associated with decreases in hepatic cholesterol, TGs with polyunsaturated fatty acids, and alterations of free hepatic FFA.

Based on the findings, researchers said, "phytosterols, at a dose comparable to that suggested for humans by the FDA for the reduction of plasma cholesterol levels, are shown to protect against NAFLD in this long-term (33-week) study".

Beta-Sitosterol may be considered a remedy for the prevention and treatment of NAFLD, pending the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of Stigmasterol and β-Sitosterol on Nonalcoholic Fatty Liver Disease in a Mouse Model: A Lipidomic Analysis by Feng S1,2,3, Gan L1, Yang CS2, Liu AB2, Lu W4, Shao P1, Dai Z5, Sun P1, Luo Z. (PubMed)

Fermented Soy Shows Lowering Blood Cholesterol Property, Clinical Diagnosis Suggests

By Kyle J. Norton

Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.

Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques to build up on the arterial wall, the major cause of heart disease and stroke.

More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.

In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).

The most common diseases associated with high cholesterol are cardiovascular disease, including coronary heart disease, stroke, and peripheral vascular disease.

Most patients with high cholesterol also have diabetes and high blood pressure.

Hyperlipidemia is a condition of abnormally high levels of cholesterol in the bloodstream.

High blood cholesterol is the most common cause of hyperlipidemia.

According to statistics provided by the CDC, more than 12% of adults age 20 and older are living with high blood cholesterol with a total cholesterol higher than 240 mg/dL. and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.

In other words, hyperlipidemia has a high prevalent ratio that affects over 100 million Americans and the condition is increasing at an alarming rate due to overweight and obesity.

Believe it or not, only half of the people with high blood cholesterol benefits from taking the lowering blood cholesterol medicine.

Fermented soy products are diverse varieties of soy food that are made from fermented soybeans, including miso, natto, tempeh, and soy sauce.

On finding a potential plant that processes high blood cholesterol activity researchers examined the health benefits of QCAN® Plus-an easily available fermented soy drink.

According to the results of the analysis of the study that was performed on lean (n = 10) and obese (n = 10) subjects during pre-soy (weeks -2, -1, and 0), on-soy (weeks 1, 2, 3, and 4), and post-soy (weeks 6, 8, 10, and 12) periods,* Total cholesterol and low-density lipoprotein (LDL) cholesterol levels were significantly reduced in both lean and obese individuals during on-soy (P ≤ .05).

* Furthermore, cytokines such as platelet-derived growth factor (PDGF) AA and AB/BB were significantly lowered on-soy compared with pre-soy (P ≤ .05) in lean subjects, and PDGF AA, IL-1RA, and GMCSF were significantly reduced on-soy (P ≤ .05) in obese subjects.

* The product is safe.

In other words, QCAN® Plus-an easily available fermented soy drink. showed a strong effect on the inhibition of high blood cholesterol and lipid oxidation.

Collectively, researchers said, "Our preliminary study on Q-CAN Plus ensures its safety for consumption and highlights its hypolipidemic and suppressive effect on certain cytokines ".

Taken altogether, fermented soy may be considered a functional food for the prevention and treatment of high blood cholesterol, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Fermented Soy Beverage Q-CAN Plus Consumption Improves Serum Cholesterol and Cytokines by Arumugam S1, Dioletis E1, Paiva R1, Fields MR2, Weiss TR2, Secor ER3, Ali A, (PubMed)

Beta-Sitosterol Inhibits the Onset of Insulin Resistance In Vivo

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.

In other words, diabetes occurs when cells in the pancreas die off or receptor sites are clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Insulin resistance is a condition in which cells that convert glucose to energy in the muscles, body fat, intestine, and liver ignore the signal of the hormone insulin signaling.

In other words, patients with insulin resistance are hyperglycemic. The syndrome is a hallmark of type 2 diabetes.

Other hallmarks of diabetes are hyperglycemia, a medical condition of abnormally high blood glucose, which is a major concern, in people with both type 1 and type 2 diabetes.

Epidemiologically, people with insulin resistance are associated with an increased risk of prediabetes, type 2 diabetes, and chronic conditions such as heart attacks, strokes, and cancer.

Most cases of insulin resistance in the Western world are involved in the clogged-up insulin receptors.
As the signals of the hormone insulin are blocked, insulin resistance develops, leading to more production of insulin by the body.

Over time insulin resistance leads to damage to the beta cell in the pancreas, an early condition of prediabetes and types 2 diabetes.

According to statistics, over 100 million Americans are living with insulin resistance. Approximately 1 in 3, including half of those age 60 and older have a silent blood sugar problem known as insulin resistance.

There are no single causes of insulin resistance, Epidemiologically, aging, ethnicity, overweight or obesity, too much belly fat, physical inactivity, smoking, and certain medical conditions such as Cushing’s disease or polycystic ovary disease are some of the prevalent factors that induce the risk of the condition.

However, most people with some of the aforementioned risk factors have never developed insulin resistance.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of diabetes, researchers investigated the anti-diabetic activity of β-sitosterol (BSS) isolated from Acacia nilotica (L.) Delile on diabetic complications.

According to the results from of experiment with ANL orally administrated (50 and 200mg/kg) to alloxanized mice (blood glucose > 200mg/dL) for 20days,

* ANL lowered (65%, P< 0.001) systemic glucose load in diabetic mice, which was otherwise 398% higher than control.

* ANL lowered (35%) insulin resistance, without any significant effect on insulin sensitivity (P> 0.05).

* Anti-hyperglycemic properties of ANL were further supported by lowering of HbA1c (34%; P< 0.001) and improved glucose utilization (OGTT).

* Hepatic (ALT, AST) and renal (creatinine, BUN) injury markers associated with the onset of diabetic complications were also lowered by the administration of ANL.

* ANL also exerted a normalization of dyslipidemia.

* The levels of oxidative stress markers MDA in the liver, kidney, and skeletal muscle were lowered through the herbal medicine antioxidant activity.

The efficacy of ANL in inhibiting insulin resistance was attributed mostly to the parts of high phenolic and flavonoid content, tocopherol, catechol, and β-sitosterol that enhance the levels of antioxidant defense protein Nrf2.

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of insulin resistance, pending the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Acacia nilotica leaf improves insulin resistance and hyperglycemia associated acute hepatic injury and nephrotoxicity by improving systemic antioxidant status in diabetic mice by Saha MR1, Dey P2, Sarkar I3, De Sarker D4, Haldar B5, Chaudhuri TK6, Sen A. (PubMed)

Yoga Practices Show to Decrease Labor Pain and Improve Delivery Outcome, Studies Suggest

Kyle J. Norton

Yoga therapy may be considered as a secondary intervention combined with standard application in improved labor pain and delivery outcome and reduced risk of pregnancy complication.

Yoga, the accident technique practice for harmonized external and internal body well-being, through breath control, meditation, bodily movement, and gesture..... has been well known for people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes and supported by health advocates.

In a randomized control trial conducted with sixty primiparous women, aged 18-35 years old, randomly assigned to either an antenatal yoga program consisted of a 1-h supervised yoga class, three times a week, starting at 26 weeks gestation or control groups, researchers after taking into account of risk factors found that at the delivery stage
1. Yoga group experienced less intensive pain, and at 2 h after the first and the second measurements in compared to control.

2. Natural delivery was found more in the yoga intervention group compared to more percentage of cesarean section in control.

3. Yoga group also demonstrated a decreased frequency of labor induction.

4. And a shorter duration of the second and third stages of labor.

With all information collected, Dr. Jahdi F, the lead author said, "Yoga during pregnancy may contribute to a reduction pain of labor and improved adequacy of childbirth".


Another study in support of the above analysis, conducted by the Prince of Songkla University, in examining the effects of a yoga program involving six, 1-h sessions at prescribed weeks of gestation during pregnancy, on maternal comfort, labor pain, and birth outcomes. also suggested that
1. Yoga group expressed higher levels of maternal comfort during labor and 2h post-labor and
2. Less labor pain
3. Although both groups experienced the same pain increase and maternal comfort at the beginning, the yoga group showed decreased pain and discomfort as labor progressed.
4. Lastly, women in yoga class had a shorter duration of the first stage of labor and a total time of labor.

More importantly, In a total of 335 women between 18 and 20 weeks of pregnancy, attending the antenatal clinic at Gunasheela Surgical and Maternity Hospital in Bangalore, India, enrolled in a prospective, matched, observational study with 169 women in the yoga group and 166 women in the control group, researchers emphasized that women participated in yoga lesson illustrated fewer complications such as preterm labor, isolated intrauterine growth retardation and pregnancy-induced hypertension at the day of delivery in comparison to those in control.

Taking all together, yoga intervention not only improved labor pain and delivery outcome but also reduced the risk of pregnancy complications, therefore yoga may be recommended to pregnant women as a preventive measurement, particularly in high-risk groups.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Yoga during pregnancy: The effects on labor pain and delivery outcomes (A randomized controlled trial). by Jahdi F1, Sheikhan F2, Haghani H3, Sharifi B4, Ghaseminejad A5, Khodarahmian M6, Rouhana N7.(PubMed)
(2) Yoga during pregnancy: effects on maternal comfort, labor pain, and birth outcomes. by Chuntharapat S1, Petpichetchian W, Hatthakit U.(PubMed)
(3) Efficacy of yoga on pregnancy outcome by Narendran S1, Nagarathna R, Narendran V, Gunasheela S, Nagendra HR.(PubMed)

Omega-3 Fatty Acids Inhibit Parameters induced by Diabetes in Vivo

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Most common types of diabetes are

* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

As of today, there is no cure for type 1 diabetes. Treatment is focusing on managing blood sugar levels with insulin injection, diet, and lifestyle change.

* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cell in pancreas dying off or receptor sites clogged up by fat and cholesterol.

The most common symptoms of type 2 diabetes are an increased thirst that won't stop with water intake, increased hunger (especially after eating), dry mouth, frequent urination, and unintentional weight loss.

* Gestational diabetes is a form of diabetes that can occur during pregnancy, affecting between 3% and 20% of pregnant women.

Women with gestational diabetes are at an increased risk of type 2 diabetes in later life.

Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of diseases associated with oxidative stress, researchers examined the antioxidant activity of Omega 3 fatty acid used in a combination with metformin (Met) in diabetic rats.

The study included 50 rats induced diabetes by the administration of streptozotocin, 15 min after the administration of nicotinamide with ten animals per group divided into the following: Control; Diabetic untreated; Diabetic + ω-3; Diabetic + metformin (metfm) and Diabetic + ω-3 + metf groups for 28 days.

Diabetes rats before treatment showed a significant increase of calcium to phosphorus ratio, tartrate-resistant acid phosphatase (TRAP), glucose and insulin resistance, and decrease of parathyroid hormone(PTH), phosphorus, total antioxidant capacity (TAC), and hepatic glycogen.

ω-3 or metformin single treatment caused significant elevations in hepatic glycogen, total alkaline phosphatase (TALP), osteocalcin, PTH, estradiol, and calcium; however, significant decreases in TRAP and glucose.

Co-administration of ω-3 and metformin caused more desirable effects on TALP, c-terminal telopeptide of type 1 collagen, estradiol, and calcium to phosphorus ratio compared to the single administration.

In other words, co-administration restored the parameter changes induced by the injection of streptozotocin-induced diabetes in tested rats.

Based on the findings, researchers said, "the combined but not the single administration of ω-3 and metformin could be preferably used in the management of bone health in the diabetic state"

Taken altogether, Omega-3 fatty acids used in a combination with other conventional medicines may be considered a functional food for the prevention and treatment of type 2 diabetes, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Co-administration of omega-3 fatty acids and metformin showed more desirable effects than the single therapy on indices of bone mineralisation but not gluco-regulatory and antioxidant markers in diabetic rats by Adeyemi WJ1, Olayaki LA2, Abdussalam TA3, Fabiyi TO2, Raji TL2, Adetunji AA. (PubMed)

Healthy Food Coffee May Normalize Sex Hormones Androgen and Estrogen Naturally, Reveal by Scientists

By Kyle J. Norton

Coffee, a popular and social beverage, is a drink made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.

A recent study suggested that coffee may have a direct effect on the influence of sex hormone steroid-binding globulin(SSBG) in stimulated production of estrogen and androgen depending on levels in the host.

Sex hormones are a class of hormones, that affect sexual development and reproduction. Steroid-binding globulin(SSBG), is a sex hormone, having a direct effect on androgen and estrogen.

In sex hormones and sexual differentiation, the most influential hormone in human sexual desire is testosterone.

Low levels of estrogen in women can also reduce sex drive caused by vaginal dryness that can lead to painful intercourse

Mentally, women with low levels of estrogen also experience unstable moods and sleep patterns that can have a strong impact on sexual desire.

However, sexual motivation is influenced by a set of hormones, including testosterone, estrogen, progesterone, oxytocin, and vasopressin...... Altogether, they control the ability to engage in sexual behaviors.

The actual causes of abnormal levels of sex hormones are debatable. But all researchers agree that aging plays an important role in the production of the sex hormone steroid-binding globulin(SSBG).


Diseases, also the risk factors associated with abnormal levels of serum of SHBG concentrations include obesity, insulin resistance, type 2 diabetes hypothyroidism, Cushing syndrome, nonalcoholic fatty liver disease, hypertension, ....... and androgen steroid use

The normal ranges for serum of SHBG concentrations in adults are:
* Males: 10 to 57 nanomoles per liter (nmol/L)
*Females (nonpregnant): 18 to 144 nmol/L

In an 8-week parallel-arm randomized controlled trial with Healthy adults (n = 42) recruited from the Boston community, including regular coffee consumers, nonsmokers, and overweight, randomized to five 6-ounce cups of caffeinated or decaffeinated instant coffee or water per day, at 4 weeks, researchers surprisingly found that
* Decaffeinated coffee drinking was associated with borderline significantly increased levels of SHBG in women, but not in men.

*. At week 4, decaffeinated coffee decreased total and free testosterone and caffeinated coffee decreased only total testosterone in women.

*. In contrast to women participants, men's consumption of caffeinated coffee displayed a significantly increased total testosterone and decreased total and free estradiol hormones.

*. The study also indicated that caffeinated coffee consumption does not exert any effect on SHBG in either men or women.

These results suggested that intake of coffee may have a strong impact in maintained normal levels of SHBG, thus reducing the risk of low levels of SHBG induced higher testosterone levels in overweight women, causing androgenization and development of polycystic ovarian syndrome.

And in men, normal levels of testosterone may also have a significant contribution to a healthy libido, building muscle mass, and maintaining energy levels.

Some researchers suggested that increased testosterone levels for middle-aged (30 to 50 years old) and older males may also improve the physical energy, strength, stamina, mental aggressiveness which were lost in the aging population.

In contrast to the above differentiation, in type 2 diabetic patients, coffee and coffee caffeine showed an elevated effect as a mediator of sex hormone-binding globulin in both androgen and estrogen particularly in women compared to healthy young adults.

Dr. Eric L. Ding and colleagues in the study to evaluate "Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men" said, " Among women, higher plasma levels of sex hormone–binding globulin were prospectively associated with a lower risk of type 2 diabetes and " the predicted odds ratio of type 2 diabetes per standard-deviation increase in the plasma level of sex hormone-binding globulin was 0.28 (95% CI, 0.13 to 0.58) among women and 0.29 (95% CI, 0.15 to 0.58) among men".

The analysis strongly suggested that coffee regardless of type has a negative correlation with the risk of diabetes through increasing levels of SHBG.

Additionally, according to the cross-sectional study of 2377 nondiabetic pre- and postmenopausal women from the E3N cohort study in a multivariate adjusted model, intake of more than 3 cups of coffee daily coffee and caffeine ≥265 mg/day was associated with an increased SHBG level distribution (<46.3 nmol/L), in compared to no risk association of decaffeinated coffee subgroup.

In other words, in low levels of SHBG nondiabetic pre- and postmenopausal in compared to healthy women, injection of caffeinated coffee increased levels of sex hormones estrogen and testosterone

The above analysis was supported by the examination of the study during a median follow-up of 10 years of 359 postmenopausal women with newly diagnosed type 2 diabetes matched with 359 control subjects by age, race, duration of follow-up, and time of blood draw, coffee and caffeine were associated to increased levels of fee and total testosterone among postmenopausal women.

In Summary, the evidence indicated that coffee and caffeine have an extreme effect on the exhibition of the sex hormone estrogen and testosterone through the increased lower level of SHBG in menopausal women and prevented the onset of type 2 diabetes without affecting the serum in healthy individuals.

Decaffeinated coffee decreased total and free testosterone through significantly increased levels of SHBG in overweight women who are at risk of diseases associated with overexpression of testosterone.

And caffeinated coffee displayed a significantly increased total testosterone and decreased total and free estradiol in men.

Altogether, coffee may be considered as a function food in mediated production of sex hormone estrogen and testosterone against diseases and syndromes caused by low levels of SSBG.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) The effects of caffeinated and decaffeinated coffee on sex hormone-binding globulin and endogenous sex hormone levels: a randomized controlled trial by Wedick NM1, Mantzoros CS, Ding EL, Brennan AM, Rosner B, Rimm EB, Hu FB, van Dam RM.(PubMed)
(2) Cross-sectional association of coffee and caffeine consumption with sex hormone-binding globulin in healthy nondiabetic women by Pihan-Le Bars F1,2, Gusto G3,4,5, Boutron-Ruault MC3,4,5, Fagherazzi G3,4,5, Bonnet F1,2,3.(PubMed)
(3) Coffee and caffeine consumption in relation to sex hormone-binding globulin and risk of type 2 diabetes in postmenopausal women by Goto A1, Song Y, Chen BH, Manson JE, Buring JE, Liu S.(PubMed)