Herbal Cayenne, the Natural Remedy for Reducing the Risk of Metabolic Dysregulation

 By Kyle J. Norton

Cayenne may be the next herbal medicine in reduced risk and treatment of metabolic dysregulation, recent study suggested

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum Annuum, the family Solanaceae, native to subtropical and tropical regions. It has been used in traditional medicine to increases metabolism, enhance the circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.

Metabolic dysregulation refers to abnormal function of the body in regulation of glucose tolerance, fasting glucose, insulin resistance, dyslipidemia,...., leading to insulin resistance, type 2 diabetes, and fatty liver disease.

Capsaicin, the major chemical compound used dietary supplement attenuated metabolic dysregulation in genetically obese diabetic mice by enhancing expression of modulation of glucose and lipid metabolism involving its receptors.

In obesity-induced inflammation and the development of obesity-related metabolic disorders, cayenne capsaicin suppressed inflammatory responses in inducing glucose intolerance and enhancing fatty acid oxidation in fat tissues, affecting insulin resistance.


The chemical compound involvement in reduced visceral adipose fat, also lowered serum levels of fasting glucose, total cholesterol, and triglycerides, probably through limited fat accumulation in adipose tissues and reduced inflammation, and increased insulin sensitivity.


Dr. Leung FW. said," Clinical evidence supports the role of capsaicin as an anti-obesity agent. Both oral and gastrointestinal exposure to capsaicin increase satiety and reduce energy and fat intake and reduction in visceral abdominal fat" and "Thermogenesis and lipid metabolism-related proteins are altered upon capsaicin treatment in white adipose tissue".

Intake of cayenne for weight loss treatment-induced reduction in visceral abdominal fat may also improve metabolic regulation. Quality of doses should only be given by specialists to prevent toxicity.


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Sources
(1) Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic mice by Kang JH1, Tsuyoshi G, Le Ngoc H, Kim HM, Tu TH, Noh HJ, Kim CS, Choe SY, Kawada T, Yoo H, Yu R.(PubMed)
(2) Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet by Kang JH1, Goto T, Han IS, Kawada T, Kim YM, Yu R.(PubMed)
(3) Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet-induced obese mice by Lee GR1, Shin MK, Yoon DJ, Kim AR, Yu R, Park NH, Han IS.(PubMed)

Herbal Alfalfa May Process Anti-Microbial Activity

By Kyle J. Norton

Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, cultivated all over the world as hay for cattle feeding, and used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance the digestive system, bleeding disorder, kidney, and urinary tract infection, etc. North American Aboriginals have used Alfalfa seeds as food, such as making bread and mush.

Alfalfa may be a potential antimicrobial agent used for the treatment of infection or infectious related diseases.

According to the Via Orabona 4, Università, chemical compound saponins found in the alfalfa family exhibited antimicrobial activities in a selection of medically important yeasts, Gram-positive and negative bacteria.

Dr. Avato P, the lead author said, "(The antimicrobial) Activity (of alfalfa)was especially high against Gram-positive bacteria (Bacillus cereus, B. Subtilis, Staphylococcus aureus, and Enterococcus Faecalis) with M. arabica being the species showing a broader spectrum of action. Discrete antifungal activity was also observed, mainly against Saccharomyces cerevisiae".

Furthermore, in the study of 40 steers fed either a sainfoin (hay or silage) or Alfalfa (hay or silage) diet over a 9-week period, in vitro, the alfalfa fed group showed a decline in fecal E. coli numbers marginally.

The study also suggested the result of the decline of anti-E. Coli number is due to the presence of phytochemical phenolics in alfalfa.


In fact, The Karunya University in the investigation of Antimicrobial Alfalfa(Medicago sativa) in various bacterial strains showed a positive effect of alfalfa seed extract in the inhibition of five bacterial strains namely Bacillus Licheniformis, Pseudomonas Aeruginosa, Lactococcus lactis, Klebsiella pneumonia. The efficacy also depends on the concentration of extract with the maximum inhibition was seen in 300µg/ml concentration of extract.

There is no doubt that intake of alfalfa regularly may be beneficial in reducing the risk and treatment of microbial infection and diseases. But further human trials are necessary.


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Sources
(1) Antimicrobial activity of saponins from Medicago sp.: structure-activity relationship by Avato P1, Bucci R, Tava A, Vitali C, Rosato A, Bialy Z, Jurzysta M.(PubMed)
(2) Potential to reduce Escherichia coli shedding in cattle feces by using sainfoin (Onobrychis viciifolia) forage, tested in vitro and in vivo by Berard NC1, Holley RA, McAllister TA, Ominski KH, Wittenberg KM, Bouchard KS, Bouchard JJ, Krause DO. (PubMed)
(3) Antimicrobial screening of Alfalfa(Medicago sativa) in various bacterial strains by G.SHEELA JOY1, and Dr.PHILOMENA GEORGE2 *. *Professor, 1B.Tech. student Department Biotechnology, Karunya University, Coimbatore, Tamil Nadu, India 641114(IJPDA)

Kidney Bean, the Potential anti-human immunodeficiency virus (anti-HIV) Natural Whole Food

By Kyle J. Norton

Kidney beans may process potential beneficial health effects in anti-human immunodeficiency virus (anti-HIV), the recent joint study suggested.
Kidney bean is a popular food, with kidney shape, strong flavor, and color in reddish-brown in nature used often as an excellent dietary selection because of enormous health benefits with a good source of protein and minerals.

Human immunodeficiency virus(HIV) is the viral cause of acquired immunodeficiency syndrome overtime, if infected.

According to the Chinese University of Hong Kong, Lectins, a class of sugar-binding proteins found abundantly in all beans, including kidney beans exhibited antiviral effects against HIV-1-RT activity.

Dr. Ng TB, the lead author in the study of inhibitory effects of antifungal proteins on human immunodeficiency virus type 1 said, "(Kidney beans exert the ability to inhibit human immunodeficiency virus type I (HIV-1) reverse transcriptase(, an enzyme regulated the formation of RNA from a DNA), protease(an enzyme that breaks down proteins and peptides) and integrase (produced by HIV virus), enzymes essential to the life cycle of HIV-1".

The study also indicated that the efficacy of all leguminous antifungal proteins with potential in inhibited HIV-1 to some extent is attributed to activities of reverse enzyme function.

Some researchers insisted that Kidney beans also exerted immunomodulatory activity in regulated presences of B and T cell immune response directed against the glycine-rich cell wall protein (GRP) in patients with different autoimmune disorders, including immune dysfunction in patients with human immunodeficiency virus (HIV) infection.

Taking all together, the Kidney beans may process anti-viral property against human immunodeficiency virus causing acquired immunodeficiency syndrome through the expression of reserve function of the certain enzyme and induced immunomodulatory exhibition in regulated B and T cell in an autoimmune response.

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Sources
(1) Phaseolus vulgaris Lectins: A Systematic Review of Characteristics and Health Implications by He S1,2,3, Simpson BK3, Sun H1, Ngadi MO4, Ma Y2, Huang T5. (PubMed)
(2) A lectin with anti-HIV-1 reverse transcriptase, antitumor, and nitric oxide inducing activities from seeds of Phaseolus vulgaris cv. extralong autumn purple bean by Fang EF1, Lin P, Wong JH, Tsao SW, Ng TB. (PubMed)
(3) Inhibitory effects of antifungal proteins on human immunodeficiency virus type 1 reverse transcriptase, protease, and integrase by Ng TB1, Au TK, Lam TL, Ye XY, Wan DC. (PubMed)
(4) A hemagglutinin from northeast red beans with immunomodulatory activity and anti-proliferative and apoptosis-inducing activities toward tumor cells by Chan YS1, Wong JH, Fang EF, Pan W, Ng TB(PubMed)
(5) Glycine-rich cell wall proteins act as specific antigen targets in autoimmune and food allergic disorders by Lunardi C1, Nanni L, Tiso M, Mingari MC, Bason C, Oliveri M, Keller B, Millo R, De Sandre G, Corrocher R, Puccetti A.(PubMed)
(6) HIV and autoimmunity by Zandman-Goddard G1, Shoenfeld Y.(PubMed)

Omega -3 Fatty Acids Inhibits the Risk and Onset of Coronary Artery Disease

By Kyle J. Norton

Cardiovascular diseases (CVD) are a group of conditions associated with blood vessels and the heart.

According to the statistics provided by the World Health Organization, cardiovascular diseases are the number 1 cause of death globally. Approximately, 17.9 million people died from CVDs in 2016, representing 31% of all global deaths.

The most common risk factors associated with CVD are an unhealthy diet, physical inactivity, smoking, and excessive alcohol drinking.

Patients with CVD mostly were found to have some intermediate conditions such as high blood pressure, cholesterol, and glucose and being overweight and obese.

Most common CVD are coronary heart disease, which is a condition of narrowing coronary arteries that lead to blockage of the blood flow in the arteries as a result of hardening arterial wall, cholesterol building up in the arteries, chemicals, such as cadmium clog up arteries, etc. affecting the small blood vessels that supply blood and oxygen to the heart. 

Coronary heart disease (CHD) is the leading cause of death in the United States.

According to statistics, coronary artery disease is the most common type of heart disease that causes the death of over 370,000 people every year, representing 28% of all death in the United States.

Sadly, according to the Centers for Disease Control and Prevention, approximately, 735,000 Americans have a heart attack each year.

What causes plaques building up on the arterial is debatable. However, researchers suggested that the Western diet is associated with a significantly increased risk of coronary artery disease.

The most common symptoms of coronary artery disease are angina, the condition characterized by chest pain or discomfort and shortness of breath as a result of the weakening of heart muscle which can not pump enough blood to the body's needs.

Over time, the prolonged weakened heart muscle can lead to complications of heart failure, irregular heartbeat, or arrhythmia.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of heart diseases, researchers examined the effects of Omega-3 polyunsaturated fatty acids on coronary artery disease.

According to the tested analysis,
* Omega-3 polyunsaturated fatty acids showed a protective activity associated with a decreased risk for myocardial infarction in populations with high marine food intake, as well as on lipid metabolism, thrombosis, and inflammation.

* Omega-3 fatty acids decrease triglyceride levels and also compete as substrates for enzymes involved in the biosynthesis of lipid mediators.

* The balance between omega-3-derived specialized pro-resolving mediators and pro-inflammatory lipid mediators from arachidonic acid metabolism against atherosclerosis, the early stage of coronary artery disease.

Collectively, researchers said, " The results of experimental, observational and randomized studies of omega-3 fatty acids are somewhat variable and should be interpreted in view of the models used and the populations studied".

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the prevention and treatment of coronary artery disease, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 fatty acids in atherosclerosis and coronary artery disease by Bäck M. (PubMed)
(2) The balance of omega-3 polyunsaturated fatty acids for -reducing residual risks in patients with coronary artery disease by Nishizaki Y1, Shimada K1, Daida H. (PubMed)

Elevated Levels Alpha-Tocopherols May Be Associated with Increasing the Risk of Uterine Fibroids

By Kyle J. Norton

Fibroids, also known as Fibromyoma uteri or leiomyoma uteri, are benign tumors originating from the muscle tissue that adhere to either the inner or outer of the uterine wall.

According to the statistic from National Uterine Fibroid Foundations, approximately 80% of all women have uterine fibroids with the majority usually have no symptoms. Every 10 minutes, 12 hysterectomies are performed in the United States alone.

If you are experiencing certain symptoms of Uterine bleeding, pelvic pressure, painful periods and sexual intercourse,  abdominal discomfort or bloating and painful defecation, it is advised that you should check with your doctor for fibroids.

After taking the family history and physical exam, diagnosis for uterine fibroids, including
* Pelvic examination
Pelvic examination when there is no menstruation and advised not to have sex for at least 24 hours, is the type of complete physical exam of a woman pelvic organ by a medical instrument to detect any infection, abnormal cells growth such as cysts, fibroid, Etc. The pap test usually is also taken. If your doctor found any abnormal cells growth or suspected uterine cancer, further tests may be suggested, including

* Pelvic ultrasound
Ultrasound allows your doctor to visualize the kidneys and around structures and to assess blood flow to the uterus as well as looking for any abnormal cells growth mass, including fibroids.

* Pelvic MRI
MRI (magnetic resonance imaging) is one of much-advanced technology used to visualize internal structures cross-sectional imaging of your body.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of females reproductive diseases, researchers examined the effect of Alpha-Tocotrienol (AT) against uterine fibroids (UFs).

According to a retrospective cohort study performed in a university teaching hospital with a total of 162 patients divided into 2 groups: with UFs and controls, the mean AT serum concentrations were 11.66 ± 4.97 μg/ml and 7.83 ± 3.13 μg/ml (medians 10.56 μg/ml and 7.42 μg/ml) in patients with UFs and controls, respectively.

In other words, women with elevated levels of mean AT serum concentrations are associated with a  factor for the onset of UTs, compared to women without UFs, particularly in Caucasian women.

Moreover, higher BMI, positive family history, and low parity were found to be major risk factors for UFs. 

Collectively, researchers said, "the development of UFs is determined by several factors, but steroids (estrogen and progesterone) and their receptors seem to play a major role in this process".

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Alpha-Tocopherol Serum Levels Are Increased in Caucasian Women with Uterine Fibroids: A Pilot Study by Ciebiera M1, Szymańska-Majchrzak J2, Sentkowska A3, Kilian K3, Rogulski Z4, Nowicka G5, Jakiel G1, Tomaszewski P6,7, Włodarczyk M. (PubMed)

Beta-Sitosterol Processes Anti Endometriosis in Vivo

By Kyle J. Norton

The endometrium is the inner lining of the mammalian uterus that is very susceptible to hormone change, particularly in the menstrual cycle.

The endometrium is also a reproductive organ where the implantation takes place. In the absence of periodic hormonal influence, before puberty or following menopause, this tissue has a constant morphology and thickness.

Endometriosis is a painful disorder characterized by endometrial cells that grow in another area in the reproductive organs, such as ovaries, fallopian tubes,..... and the tissue lining your pelvis, outside of the uterus.

The causes of endometriosis are debatable. Some researchers suggested that normally a layer of the endometrial lining in the inside of the uterus is expelled through menstruation, during the last stage of the menstrual cycle, instead, some of the endometrial tissues grow somewhere else in the body, causing endometriosis.

According to the stage of severity, endometriosis can be classified into, 

* Minimal stage:
The top surface, few in number. Commonly they are found in the inside wall of uterus, ligaments, and ovary.

*  Mild stage:
Deeper implants, greater numbers are presented. Commonly found in the same area as a minimal stage.

* Moderate stage:
Many implants, endometrial cysts present, affecting ovary function, causing scar tissues and adhesion is also present.

* Severe stage:
Intensive peritoneal implants, large endometromas present and dense adhesion.

Each woman experiences differently from endometriosis. Some women may have extensive endometrial tissues in their body but feel little or no pain at all, while other women may only be in the early stage of endometriosis but have excessive pain.

Beta-Sitosterol is a phytochemical in the class of phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of reproductive diseases in women, researchers examined the effects of Anthemis austriaca Jacq. flowers in gynecological disorders, on the rat endometriosis model.

According to the results of the administration of the extracts from n-hexane, ethyl acetate (EtOAc), and methanol (MeOH) isolated from the Anthemis austriaca Jacq. flowers,
* The MeOH extract reduced the adhesion scores and endometrial foci areas from 3.1 to 1.1 (p < 0.01) and from 86.4 to 40.5 (p < 0.01), respectively

* Furthermore, the MeOH extract reduced tumor necrosis factor (TNF)-α, vascular endothelial growth factor (VEGF), and interleukin (IL)-6 levels of the peritoneal fluids from 13.7 to 3.8 (p < 0.01), from 28.4 to 16.3 (p < 0.05) and from 50.2 to 24.3 (p < 0.01), respectively.

* Interestingly, After the MeOH extract was fractionated, the obtained subfractions A and C of the MeOH extract displayed statistically significant activity on the endometriosis rat model, particularly the compound β-sitosterol-3-O-β-D-glucopyranoside.

Based on the findings, researchers said, "flavonoids and sterols of the plant were detected as the possible compounds responsible for the activity".

Beta-Sitosterol, a major compound of sterols may be considered a remedy for the prevention and treatment of endometriosis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Promising activity of Anthemis austriaca Jacq. on the endometriosis rat model and isolation of its active constituents by Ilhan M1,2,3, Ali Z3, Khan IA3, Taştan H4, Küpeli Akkol E. (PubMed)

Tocopherols, the Potential Phytochemical That Protects Diabetics Against Diabetics Nephropathy

By Kyle J. Norton
Diabetic nephropathy (diabetic kidney disease) is a complication of kidney damage caused by diabetes.

Long-term unmanaged hyperglycemia can damage parts of the kidneys, thus reducing the kidney function in filtering waste from the blood filters, leading to 'leaky' syndrome that allows protein into your urine.

Diabetic nephropathy is the 3 stages of kidney change in patients with diabetes. In this stage, patients may experience symptoms of abnormally elevated urinary albumin excretion, compared to the 15 and 300 μg/min in the baseline situation.

The progression of diabetic nephropathy that leads to an increased rate in albumin excretion is higher in patients with increased blood pressure.

More importantly, if high blood pressure is left untreated, diabetic nephropathy can induce persistent proteinuria >0.5 g/ 24 h that furtherly declines the renal function with the mean fall rate being around 1 ml/min/mo.

Epidemiologically, diabetic nephropathy is also associated with cardiovascular disease and increased the mortality of diabetic patients.

Metabolic and hemodynamic alterations, oxidative stress, and activation of the renin-angiotensin system are some of the risk factors that have been found in patients with Dn.

Inflammation is a natural defense of the immune system that protects the body against the insult from the foreign invasion.

Acute inflammation occurs quickly or within the hours and lasts a few days or weeks and the damaged tissues are healed itself after all pathogens are killed off.

However, if the immune system can not completely destroy all invaders in the acute phase of infection, it will compromise, leading to chronic low-grade inflammation, a major cause of cardiovascular disease, arthritis, and diabetes.

Tocopherols are phytochemicals of which many have vitamin E activity, belongings to the group of lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of chronic disease complications, researchers examined the effect of tocopherol against diabetics nephropathy.

According to the analysis,
* The intraperitoneally administered d-α-tocopherol (vitamin E, αToc) induces an amelioration of DN in vivo through the activation of DGKα and the prevention of podocyte loss involved in renal damage.

Where diacylglycerol kinase (DGK) that regulates numerous cellular responses can attenuate protein kinase C (PKC) activity and diacylglycerol (DAG) initiated by hyperglycemia.

* Oral administration of αToc on DN induced by streptozocin-induced diabetic mice also significantly ameliorated the symptoms of DN by preventing the loss of podocytes, associated with chronic renal diseases through normalizing the levels of protein kinase C (PKC).

Taken altogether, tocopherols may be considered adjunct therapies in the prevention and treatment of diabetics nephropathy, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Amelioration of diabetic nephropathy by oral administration of d-α-tocopherol and its mechanisms by Hayashi D1, Ueda S1, Yamanoue M1, Ashida H1, Shirai Y. (PubMed)