Herbal Angelica Protects Diabetics Against Renal Damage

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

There are 2 major types of diabetes

Most common types of diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cell in pancreas dying off or receptor sites clogged up by fat and cholesterol.

The kidneys formed part of the secretary system are two bean-shaped organs located against the back muscles in the upper abdominal area.

The kidneys play a critical role in filtering wastes from the breakdown of active muscle and the food you eat and removing extra water from the blood through urinary secretion.

Furthermore, the kidneys also maintain the fluid in the body by secreting extra water through urinary secretion.

Kidney dysfunction reduces the body's ability to clean and filter extra water from your blood, leading to fluid retention and high blood pressure in the early stage. Believe it or not, people with a kidney function of 10% do not show signs of kidney dysfunction and symptoms.

In other words, kidney disease often has no symptoms until at a very advanced stage.

Diabetic kidney damage is a type of kidney injury caused by diabetes.

Kidney damage caused by diabetes usually occurs slowly, over many years. The injury can also lead to other health problems, including high blood pressure and glomerulonephritis,, an inflammation of the kidney's filtering units.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a natural compound for the treatment of kidney diseases, the researchers examined the effects of an arabinoglucan (AG) isolated from Angelica Sinensis on diabetic nephropathy (DN) induced in rats by streptozotocin.

The rats intraperitoneally treated with AG for 8 weeks induced Diabetes exhibited renal dysfunction, as evidenced by reduced creatinine clearance, increased blood urea nitrogen and proteinuria, along with the marked enhanced mesangial expansion.

Overproliferation of glomerular mesangial cells (GMCs) that remove trapped residues and aggregated protein halted by AG treatment

Furthermore, AG treatment rats also inhibited the and inflammation mediators associated with inflammatory cytokines.

Moreover, AG also significantly inhibited the expression of nuclear factor-κB (NF-κB) against inflammation and receptor for advanced glycation end products (RAGE) induced oxidative stress by interacting and binding to RAGE,  both in diabetic kidneys and in high glucose-induced GMCs.

Based on the findings, researchers said, " AG, acting as a RAGE antagonist, is a promising agent for the prevention and treatment of DN".

Taken altogether, Herbal Angelica may protect the diabetics kidney against DN, pending to larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A branched arabinoglucan from Angelica sinensis ameliorates diabetic renal damage in rats by Sui Y1, Liu W1,2, Tian W3, Li XQ3,4, Cao W. (PubMed)

Dandelion (Taraxacum officinale), the Potential Anti-HIV-1 Infection Functional Remedy

By Kyle J. Norton

Human immunodeficiency virus -1 (HIV-1) is one of 2 types of HIV precipitated of acquired immunodeficiency syndrome (AIDS), transmitted through direct contact with HIV-infected body fluids, including blood, semen, and genital secretions,...

Acquired immunodeficiency syndrome (AIDS) is a chronic condition caused by the infection of the human immunodeficiency virus (HIV).

According to epidemiological studies, people who have serval sexual partners are the most at risk of HIV infection.

However, the virus can also transmit through infected blood transfusion, infected mother to children.

People in the early stage infected by the virus may experience some acute symptoms caused by the immune response, including fever sore throat, rash, muscle and joint aches and pains, headache,...

If untreated, the virus will slowly multiply and destroy the cells of the immune system, leading to chronic signs and symptoms of fever, fatigue, swollen lymph nodes,...

In the late stage, HIV-1 may severely damage the immune system, making the infected host vulnerable to a variety of life-threatening diseases and cancers. If an infected individual has the numbers of T-cell count below 200, the person is considered to have AIDs.

According to the statistic, AIDS is the fifth leading cause of death in the US.

People between ages 25 and 44 in the United States are at substantially higher risk compared to other age groups.

Approximately 36.7 million people worldwide living with HIV/AIDS in 2016, including, 2.1 million children less than 15 years of age.

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the Taraxacum officinale (dandelion) anti-HIV-1 activity.

According to the tested differentiation, in vitro, compared to control values obtained from cells infected without treatment, treatment of dandelion showed a low level of HIV-1 replication.

Furthermore, the treatment of dandelion also exerted a strong effect on the viral transcriptase activity in a dose-dependent manner.

In other words, the dandelion extract has potent inhibitory activity against HIV-1 replication and reverse transcriptase activity to induce infection.

Based on the results, researchers suggest, " These findings provide additional support for the potential therapeutic efficacy of Taraxacum officinale. Extracts from this plant may be regarded as another starting point for the development of antiretroviral therapy with fewer side effects".

Taken altogether, Dandelion may be considered a remedy for the protection against HIV-1 infection, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Inhibitory effect of aqueous Dandelion extract on HIV-1 replication and reverse transcriptase activity by Han H1, He W, Wang W, Gao B. (PubMed)

Common Fig or Fig (Ficus carica) Gobbles Up Glioblastoma GBM Cells in Vitro

By Kyle J. Norton



The brain and spinal cord made up the nervous system. Brain and Spinal Cord tumors originating are not very common. Most primary tumors are caused by abnormal cell growth that surrounds and supports neurons, with a small number may be caused by gene defect from exposure to radiation or toxic chemicals. Benign tumors are noncancerous, and malignant tumors are cancerous.

More than 190.000 people in the US are diagnosed with a brain tumor each year alone.

Brain cancer is a medical and chronic condition characterized by cell growth disorderly in the brain tissue.

Glioblastoma or glioblastoma (also called GBM) caused mostly by the abnormal astrocytic cells and dead cells (necrosis) is considered one of the most aggressive cancers induced by the alternation of cells originated from the brain, including the cerebral hemispheres.

Most patients with GBM experience symptoms of brain swelling caused by the overexpression of the fluid surrounding the tumor.

Conventionally, due to the nature of rapid growth, surgery is necessary to relieve the brain pressure and remove the tumor as much as possible, followed by radiation and chemotherapy.

According to the statistics, in the US, the incidence affects mostly in the elderly with the diagnosed rate of 3.19 per 100,000 persons. The disease is rare in children.

GBM is deadly, patients with GBM have a median survival of less than one year and less than 2% of patients survive three years or more.

Fig is a species of F. Carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.

On finding natural compounds for the treatment of neurological diseases, researchers examined the cancer suppressive effect of Ficus carica (fig) latex (FCL) on glioblastoma (GBM).

On T98G, U-138 MG, and U-87 MG GBM cell lines treated by the combination of FCL and  FCL-temozolomide (TMZ), according to the tested differentiation,

* FCL causes cell death in GBM cells with different responses to FCL-temozolomide (TMZ), an oral chemotherapy drug.

* The cell death was attributed synergistically increased in combination with TMZ

* More importantly, the effect of FCL on the modulation of let-7d expression by suppressing proliferation and cell migration may be an important underlying mechanism of the anti-invasive effect of this extract.

Taken altogether, common fig or fig (Ficus carica)  used in a combination with chemo drug may be considered a remedy for the treatment of glioblastoma (GBM), pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Ficus carica latex prevents invasion through induction of let-7d expression in GBM cell lines by Tezcan G1, Tunca B, Bekar A, Yalcin M, Sahin S, Budak F, Cecener G, Egeli U, Demir C, Guvenc G, Yilmaz G, Erkan LG, Malyer H, Taskapilioglu MO, Evrensel T, Bilir A. (PubMed)

Broccoli, the Natural Antioxidants

By Kyle J. Norton

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

However, in people with a weakened immune system, intake dietary sources of antioxidants may be necessary.

There are 3 main types of antioxidants found in nature, including
* Antioxidant enzymes produced by the host, including superoxide dismutase (SOD), glutathione peroxidase, glutathione reductase, and catalases.

* Antioxidants vitamins, that may be injected from the dietary sources such as fruits and vegetables, including vitamins A, C, D, and E. Most antioxidant vitamins are considered free radical scavengers that gobble up free radicals before they can induce a cascade of damage.

* Antioxidant Phytochemicals found in the plant including second metabolites.

Antioxidants keep our bodies functioning properly by reducing the risk of diseases associated with oxidative stress.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.

This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.

Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.

With an aim to find a natural food for the prevention and treatment of diseases associated with oxidative stress, researchers examined the phytochemical composition of 3 different purple sprouting broccoli varieties according to with their production cycle: EEP (Extra Early), EP (Early), and LP (Late) antioxidant activity.

The leaves of EP variety seems the richest in total phenolic acids, whereas the number of anthocyanins was higher in LP variety.

The levels of glucosinolates were higher in purple broccoli than in green cultivars and also higher than other purple broccolis grown under different climate conditions.

Additionally, EEP, EP, and LP purple sprouting broccoli varieties grown under the Mediterranean climate. showed a number of health-promoting nutrients and natural antioxidants.

The vitamin C, phenolic compounds, and glucosinolates in these purple varieties were higher than in traditionally grown green broccoli and other purple broccolis grown under different climate conditions.

Taken altogether, broccoli varieties may be considered antioxidant supplements for the prevention of oxidative stress disease, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Natural antioxidants in purple sprouting broccoli under Mediterranean climate by Rodríguez-Hernández Mdel C1, Moreno DA, Carvajal M, García-Viguera C, Martínez-Ballesta Mdel C. (PubMed)

Beta-Sitosterol Reduces the Onset of Gouty Arthritis in Vivo

By Kyle J. Norton

Arthritis is a general form of the inflammatory disease associated with the inflammation of one or more joints.

The most common symptoms are joint pain and stiffness found mostly in the aging population.

The most common caused of arthritis is a joint injury that did not heal properly, metabolic abnormalities caused by overexpression of uric acid and infection-induced bacteria or virus.

However, there are some cases of arthritis caused by autoimmunity, a condition in which the immune system mistakenly attacks the joint tissues, such as in rheumatoid arthritis and systemic lupus erythematosus.

According to the information provided by the Arthritis Foundation, in the US, approximately 54 million adults are living with the condition.

Believe it or not, almost 300,000 babies and children have arthritis or a rheumatic condition.

Gout, a painful and recurrent condition mostly affected one joint is a type of arthritis caused by uric acid building up in the blood that induces joint inflammation.

Epidemiologically, high levels of uric acid found in the body that leads to the forming of crystals are the culprit, caused by the inability of the kidney to get rid of uric acid.

Most cases of gout are found in patients who follow the diet with a high intake of meats and seafood and foods containing higher levels of purine such as alcoholic beverages, especially beer, and drinks sweetened with fruit sugar (fructose).

Reduced intake of the aforementioned products has been found to reduce the onset of recurrence of the condition in many previous patients.

Believe it or not, most patients with gout and recurrent gout also associated with medical conditions of hypertension, renal insufficiency, and hypertriglyceridemia.

Gouty arthritis is a form of inflammatory arthritis associated with high levels of uric acid in the blood that lead to sudden, severe episodes of pain, tenderness, redness, warmth, and swelling of the joints.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of arthritis, researchers examined the effects of ethanolic extract of L. trichocarpha, its ethyl acetate fraction and its main bioactive compounds on gouty arthritis by countering hyperuricemia and inflammation.

According to the results of an experimental model of gouty arthritis,
* Crude ethanolic extract and its ethyl acetate fraction showed significant urate-lowering effects.

* LTE was also able to significantly inhibit liver xanthine oxidase (XOD) activity in vivo at the dose of 250mg/kg.

\
* LTE, LTA, lupeol, β-sitosterol, lychnopholide, eremantholide, luteolin, and apigenin showed strong inhibitory activity against monosodium urate crystals-induced paw edema in mice.

Based on the findings, researchers said, "Ethanolic extract of Lychnophora trichocarpha and some of its bioactive compounds may be promising agents for the treatment of gouty arthritis since they possess both anti-hyperuricemic and anti-inflammatory properties.".

Taken altogether, beta-Sitosterol found abundantly in Lychnophora trichocarpha may be considered a supplement for the prevention and treatment of gouty arthritis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis: anti-hyperuricemic and anti-inflammatory effects of its extract, fraction and constituents by de Souza MR1, de Paula CA, Pereira de Resende ML, Grabe-Guimarães A, de Souza Filho JD, Saúde-Guimarães DA. (PubMed)

Omega-3 Fatty Acids, the Potent Lipid Inflammatory Mediators in Vitro and Vivo

By Kyle J. Norton


Inflammation is a natural response by the immune system to protect the body against the invasion of stimuli or foreign pathogens.

Acute inflammation is a short-term condition caused by tissue injury, leading to pain, redness, swelling, and heat to the affected area. depending on the size of the injury. Some patients with acute inflammation may also experience the symptom of loss of function.

In acute inflammation, the white blood cells on the first line of defense of the immune system after sensing the danger of an infection in the body through a message from the brain stimulate the production of platelets to cover the site of injury or damage and inflammatory cytokines to kill off all pathogens before they can cause harm to the body.

Most cases of infection are stopped at the acute phase. The wound or injury is slowly recovered.

However, people with a weakened immune system, acute inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, which may lead to low-grade chronic inflammation.

Lipids mediators, derived from the omega-6 polyunsaturated fatty acids (PUFA) are potent enhancers of innate and adaptive immune activation in numerous inflammatory disorders.

Dr. Bennett M, the lead scientist in the examing "Lipid Mediators in Inflammation" wrote, "Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), each lipid displays unique properties, thus making their role in inflammation distinct from that of other lipids derived from the same PUFA".

In other words, each individual acid arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), each lipid displays unique properties which are derived from polyunsaturated fatty acids (PUFAs), plays a selective role in maintaining cellular process depending on the types of fatty acid.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of inflammatory diseases, researchers examined the effects of n3-PUFA DHA and its derived specialized pro-resolving lipid mediators (SPMs) MaR1, RvD1, and RvD2, on TNF-α inhibition of intestinal sugar and glutamine uptake.

Based on the differentiation,

* DHA blocked TNF-α-induced inhibition of α-methyl-D-glucose (αMG) uptake, an analog of glucose and SGLT1, a glucose transporter, expression in the apical membrane of Caco-2 cells.

* Compared to DHA, SPMs showed the same preventive effect at concentrations 1000 times lower.

* In diet-induced obese (DIO) mice, oral gavage of SPMs, MaR1 reversed the up-regulation of pro-inflammatory cytokines found in the intestinal mucosa of these mice without inducing a reduced intestinal transport of αMG and SGLT1 expression in the DIO mice.

* In Caco-2 cells, EPA, DHA, and the DHA-derived SPMs. also prevent the TNF-α in the inhibition of glutamine uptake.

Collectively, scientists said, " DHA and its SPMs as promising biomolecules to restore intestinal nutrients transport during intestinal inflammation".

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the treatment of diseases associated with the impaired lipid inflammatory mediators, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) DHA and its derived lipid mediators MaR1, RvD1 and RvD2 block TNF-α inhibition of intestinal sugar and glutamine uptake in Caco-2 cells by Castilla-Madrigal R1, Gil-Iturbe E1, López de Calle M2, Moreno-Aliaga MJ3, Lostao MP. (PubMed)

Beta-Sitosterol Inhibits the Parameters Associated with the Risk of Diabetes

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

There are 2 major types of diabetes,

* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cell in pancreas dying off or receptor sites clogged up by fat and cholesterol.

The most common symptoms of type 2 diabetes are an increased thirst that won't stop with water intake, increased hunger.

Diabetic complications are any diseases associated with hyperglycemia if the blood glucose is not managed properly. Patients with diabetes may induce a number of complications including cardiovascular disease, neuropathy, nephropathy, retinopathy, and foot ulcer.

By managing your blood glucose properly and daily, the risk of diabetic complications can be reduced in diabetics by
*Taking your medication as directed.

*Keeping tight control of your blood sugar or managing the blood glucose in the required range

* Eating healthy with moderate exercise to protect your weight, blood pressure and cholesterol. Overweight, blood pressure and cholesterol are some of the conditions associated with increased risk of diabetes complications.

* Get regular checkups

* Quit smoking

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention of chronic diseases involved in oxidative stress, researchers investigated the anti-diabetes activity of beta-sitosterol (β-sitosterol) on insulin signaling molecules and glucose oxidation.

According to the differentiation of the adipose tissue of high-fat diet and sucrose-induced type-2 diabetic experimental rats given the dose of β-sitosterol (20 mg/kg b.wt, orally for 30 days), β-sitosterol normalized the altered levels of blood glucose, serum insulin in the tested rats.


Furthermore, the hormone testosterone, lipid profile, oxidative stress markers, antioxidant enzymes, insulin receptor (IR), and glucose transporter 4 (GLUT4) proteins associated with glucose uptake were also inhibited by the application of beta-sitosterol.

In other words, most parameters associated with the characteristics of diabetes were inhibited by the injection of the bioactive compound.

Based on the findings, researchers aid, "β-sitosterol improves glycemic control through activation of IR and GLUT4 in the adipose tissue of high fat and sucrose-induced type-2 diabetic rats".

Taken altogether, beta-Sitosterol may be considered a supplement for the treatment of diabetes, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) In silico and in vivo analysis to identify the antidiabetic activity of beta sitosterol in adipose tissue of high fat diet and sucrose induced type-2 diabetic experimental rats by Ponnulakshmi R1, Shyamaladevi B2, Vijayalakshmi P3, Selvaraj J. (PubMed).