Saturday, 25 April 2020

Cranberry, the Prebiotic and Anti-Bacterial Functional Food

By Kyle J. Norton

Compared to probiotics, prebiotics are compound in food that induces the growth or activity of beneficial microorganisms in the gut.

In other definition, they are special forms of dietary fiber that act as fertilizers to promote the growth of good bacteria in your gut.

In the gastrointestinal tract, prebiotics can alter the composition of organisms in the gut microbiome.

In other words, prebiotics raises the levels of healthy bacteria against bad bacteria.

Gut microbiota is a complex community with over trillion microorganisms that live in our digestive tracts.

In healthy individuals, the ratio of good and bad microorganisms is balanced. In other words, healthy gut microbiota levels maintain the structure and function of the gastrointestinal tract.

In fact, a balanced ratio of gut microbiota plays a critical role in the digestion of certain foods that the stomach and small intestine have not been able to digest, in the production vitamins, improvement of digestive functioning and modulation of the immune function.

The use of antibiotics has been found to damage the gut ecosystem, leading to certain chronic illnesses such as inflammatory bowel disease, obesity, cancer, and autism.

Further, the unbalanced ratio of gut microbiota functions also alters immune homeostasis, leading to the onset of autoimmune disorders which in turn can induce intestinal and systemic autoimmune diseases.

On finding a potential compound for the treatment of digestive diseases researchers investigated the cranberry prebiotic or antimicrobial effect on gut microbiota.

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

According to the results of the analysis, cranberry extracts and whole cranberry powder showed a strong activity that broadly modulates the gut microbiota by reducing the abundance of Enterobacteriaceae and increasing the abundance of Bacteroidaceae.

In other words, cranberry extracts and whole cranberry powder improved the ratio of gut microbiota by increasing the population of good bacteria and reducing the numbers of bad bacteria.

In a gut simulator, more precisely, salicylate found in cranberry showed a major contribution to reduce levels of Enterobacteriaceae and elevated Bacteroidaceae in a dose-dependent manner.

Taken altogether, cranberry combined with other herbal medicine may be considered a prebiotic and antimicrobial remedy for the treatment of digestive diseases, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cranberry extracts promote growth of Bacteroidaceae and decrease abundance of Enterobacteriaceae in a human gut simulator model by O'Connor K1, Morrissette M1, Strandwitz P1, Ghiglieri M1, Caboni M1, Liu H2, Khoo C2, D'Onofrio A1, Lewis K. (PubMed)

Green Peas (Pisum Sativum) Improves Insulin Sensitivity in Vivo

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.


Insulin sensitivity is a term to measure how sensitive the body's cells are in response to insulin. 

In other words, in insulin resistance subject, signals sent out by the hormone insulin was ignored by the cell of the muscles, body fat, and liver that process the function to convert glucose into energy.

Epidemiologically, people with insulin resistance are associated with an increased risk of prediabetes, type 2 diabetes and chronic conditions such as heart attacks, strokes, and cancer.


Insulin resistance is considered a hallmark of type II diabetes and a condition in the cluster of metabolic syndrome.

There is no single cause of insulin resistance. Medical conditions, being extreme overweight, ethnicity, genetic proposition, and physical inactivity are some of the prevalent risks of insulin resistance.

Most cases of insulin resistance in the Western world are involved in the clogged up insulin receptors.
As the signals of hormone insulin are blocked, insulin resistance develops, leading to more production of insulin by the pancreas.

Over time insulin resistance that leads to damage to the beta cell in the pancreas, an early condition of prediabetes and types 2 diabetes.

According to the US statistics, approximately, 60 to 70 million individuals are affected by insulin resistance with 40% of individuals older than 50 years may be at risk for insulin resistance.

Green peas are species of Pisum Sativum belongings to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalaya Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.

On finding a potent ingredient for the treatment of diabetes, researchers investigated the total RNA extracted from livers of rats fed a high-fat diet (HFD) or HFD + pea hulls (PH) diet.

According to the tested analysis,
* PH group showed a significant increase in the intermediaries of β-oxidation: C16-OH and C16:1 acylcarnitines (>50%, p < 0.05) and 3-hydroxybutyrate (100%, p < 0.05), a catabolic process that fatty acid molecules are broken down, compared with the HFD group.

Where increased 3-hydroxybutyrate levels are associated with insulin sensitivity and reduced demand for insulin.

* mRNA of Hadha, a gene involved in β-oxidation, was significantly reduced by 53% (p < 0.005) in the PH group compared with the HFD group,

* Levels of peroxisome-proliferator-activated receptor alpha (PPAR-α) associated with lipid metabolism in the liver were no different in both groups.

Based on the results, scientists said, " feeding PH alters lipid metabolism in the liver, which may contribute to improved glucose tolerance in insulin-resistant rats".

Taken altogether, green peas may be considered a functional food for the treatment of insulin resistance,  pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Improved glucose tolerance in insulin-resistant rats after pea hull feeding is associated with changes in lipid metabolism-targeted transcriptome by Chan CB1, Gupta J, Kozicky L, Hashemi Z, Yang K. (PubMed)

Friday, 24 April 2020

Healthy Food Cabbage Protects the Cells Integrity Against Oxidative Stress

By Kyle J. Norton

Oxidative stress is a condition caused by an imbalance of the ratio of free radicals and antioxidants in the body.

In other words, oxidative stress is either caused by overexpression of free radical or depletion of antioxidant enzymes in the body.

Some researchers suggested that oxidative stress may also arise due to the chain reaction of free radicals in which free radicals donate or intercept an electron from other stable molecules.

Long-term oxidative stress presented in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including cardiovascular disease, diabetes, and cancer.

More precisely, exogenous factors, such as cigarette smoke, and endogenous factors, such as the oxidative burst from activated macrophages are some of the factors involved in the risk of oxidative stress.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.

Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.

This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.

On findings a natural wholefood for the prevention and treatment of diseases associated with oxidative stress, researchers investigated the effects of red cabbage anthocyanin (RCA)-enriched extract on H₂O₂ expression on HepG2 cells.

According to chemical analysis, all derivatives of cyanidin (268 ± 2 μg/mg) found in RCA, mainly with 19% nonacylated, 51% monoacylated, and 31% diacylated structures with ferulic, sinapic, p-coumaric, and caffeic acids exerted antioxidant activity against the oxidative stress induced by the injection of H₂O₂.

Furthermore, the application of RCA extracts markedly ameliorated cell apoptosis and improved viability.

Moreover, in another study, cabbage extract protected against H2O2-induced cell death and did not elicit any cytotoxic effects by suppressing ROS production and increasing the expression of antioxidant proteins (SOD-1, catalase, and GPx) produced by the host.

In oxidative stress-exposed H9c2 cells, the protective effects of cabbage extract also inhibited apoptotic responses and activation of MAPK proteins (ERK1/2, JNK, and p-38) involved in the resistance of apoptosis by preserving mitochondrial functions.

Based on the results, researchers wrote, "cabbage extract protects against oxidative stress and suggests that it can be used as an alternative therapeutic strategy to prevent the oxidative stress in the heart".

Taken altogether, cabbage may be used as a functional food for the prevention and treatment of diseases associated with oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.




Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Characterization of Purified Red Cabbage Anthocyanins: Improvement in HPLC Separation and Protective Effect against H₂O₂-Induced Oxidative Stress in HepG2 Cells by Fang S1, Lin F2, Qu D3, Liang X4, Wang L. (PubMed)
(2) Cabbage (Brassica oleracea var. capitata) Protects against H2O2-Induced Oxidative Stress by Preventing Mitochondrial Dysfunction in H9c2 Cardiomyoblasts by Yang DK. (PubMed)

Elecampane (Inula helenium) Destroys Lung Cancer Cells in Vitro

By Kyle J. Norton

The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream to nourish the body cells' need and exhaling carbon dioxide from the bloodstream.

Lung cancer is defined as a condition of the abnormal growth of the cells in the lung's tissue. The most common forms of primary lung cancers are derived from epithelial cells.


The most common form of primary lung cancers is derived from epithelial cells.

The exact cause of lung cancer is not identified. However, epidemiologically, smoking, second smoke, exposure to certain chemicals, family history, people who have lung disease and excessive drinking are some prevalent factors associated with lung cancer developing.

According to the statistics provided by the American cancer society, Lung cancer accounts for 14% of all new cancers diagnosed in the US. In 2018, there were about 234,030 new cases of lung cancer (121,680 in men and 112,350 in women). Lung cancer also causes the death of 83,550 in men and 70,500 in women in the same year.

Lung cancer can be classified into 2 major types
* Non-small cell lung cancer is the most common type of lung cancer that usually grows and spreads methodically and predictably.

* Small cell lung cancer is a fast-growing type of lung cancer, that can spread to distant parts of the body in a relatively early stage.


On finding a natural ingredient for the prevention and treatment of lung diseases, scientists examined the anti-lung cancer effects of Alantolactone (ALT), a sesquiterpene lactone compound isolated from Inula helenium.

Elecampane, also known as Horse-heal (Inula helenium) is a perennial composite plant, genus nulla, belonging to Asteraceae, native to Southern Europe, and Asia. 

The plant has been used in traditional and herbal medicine in treating bronchitis or emphysema, night sweats, pulmonary tuberculosis, irritating cough, catarrhal discharges, etc.

According to tested analysis,
* ALT inhibited cell growth and induced S‑phase arrest and cell apoptosis in A549 and NCI‑H520 cells.

* ALT increased the level of ROS, inhibited the Akt/glycogen synthase kinase (GSK)3β pathway and induced endoplasmic reticulum (ER) stress to prevent proliferation and cause apoptosis of A549 and NCI‑H520 cells.

* Most importantly, ALT treatment sensitized lung cancer cells to Gemcitabine (GEM) by enhancing the chemo drug efficacy.

Based on the results, researchers suggest, "combined treatment with ALT and GEM may have potential as a clinical strategy for lung cancer treatment".

Taken altogether, Dandelion may be considered a remedy for the treatment of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway by Wang J1, Zhang Y1, Liu X2, Wang J2, Li B3, Liu Y3, Wang J. (PubMed)

Thursday, 23 April 2020

Fermented Soy Improves Brain Blood Flow in Post-Stroke Hyperglycemia in Vivo

By Kyle J. Norton

Stroke is a medical condition in which the brain function is interrupted rapidly due to the loss of blood supply caused by the blockage of blood such as thrombosis and arterial embolism, or leakage of blood that lead to the death of brain cells.

Stroke is a condition associated with the plagues build-up in the arteries and high blood pressure. 

In other words, if plagues building up in the arteries is blocking the circulation of blood in any part of the brain, causing oxygen not to be delivered to the brain, resulting in some cells in the brain to die off and are unable reproduce,

Besides cancer and heart diseases, stroke is the third leading cause of death. Approximately 1/4 of all stroke victims die as a direct result of the stroke or its complications.

According to the statistics of the Heart and Stroke Foundation, strokes kill 45% more women than men in Canada.

There are 2 types of stroke
* Ischemic stroke is the most common type of stroke accounting for almost 80% of all strokes.

* Hemorrhagic stroke occurs when a blood vessel bursts inside the brain, causing an increase of the fluid pressure on the brain and harms the brain by pressing it against the skull.

Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.

Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.

Untreated hyperglycemia has been found to induce ketoacidosis characterized by the symptoms shortness of breath, breath that smells fruity and gastrointestinal discomforts such as nausea, vomiting, and dry mouth.

The post-stroke hyperglycemia management is the interventions associated with the management of physiological variables such as blood glucose, blood pressure, hypoxia, hydration, and temperature


Fermented soy products are diverse varieties of soy food that are made from fermented soybeans, including miso, natto, tempeh, and soy sauce.


On finding a potential plant for the neuroprotection after stroke, researchers examined the effect of chungkookjang made with Sunchang Research Center for Fermentation Microbes 100730 and 100731 strains of Bacillus amyloliquefaciens(SRCM100730; CKJ730) and SRCM100731(CKJ731) on post-stroke hyperglycemia in Mongolian gerbils.

Where the Gerbil which either was fed 4.5% cooked soybeans (CSB), CKJ730, CKJ731, or cellulose (negative-control) in 40 energy% fat diets for 3 weeks, and then had artery occlusion for 8 min and continued taking the assigned diet for 5 weeks.

According to the results of the analysis,
* CKJ730 and CKJ731 had thrombolytic activity and prevented neuronal cell death.

* CKJ730 protected against post-stroke glucose dysregulation by restoring β-cell mass in the gerbils with transient artery occlusion.

* Serum tumor necrosis factor-α and interleukin-1β levels were lower in CKJ730 and CKJ731 than the negative control.

* CSB also improved glucose metabolism and suppressed inflammatory cytokines, but less than CKJ730 and CKJ731.

* Clostridia increased, and Bacteriodia slightly decreased in the negative-control group, compared to the normal control.

Collectively, researchers said, "the daily intake of chungkookjang fermented with B. amyloliquefaciens improved the gut microbiome, increased blood flow to the brain, suppressed systemic inflammation".

Taken altogether, potato may be considered a functional food for the prevention and treatment of post-stroke hyperglycemia-induced complications,, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Chungkookjang, a soy food, fermented with Bacillus amyloliquefaciens protects gerbils against ishcmeic stroke injury, and post-stroke hyperglycemia by Jeong DY1, Jeong SY1, Zhang T2, Wu X2, Qiu JY2, Park S. (PubMed)

Omega 3 Fatty Acid Inhibits the Onset of Acute Dyslipidemia

By Kyle J. Norton

Fat including cholesterol and triglycerides consists of hydrocarbon molecules.

Dyslipidemia is a condition of abnormal levels of lipids in their blood.

Hyperlipidemia is a medical condition characterized by abnormally high levels of cholesterol in the bloodstream.

Overexpression of cholesterol levels in the bloodstream has been linked to plaques accumulation on the arterial walls, a major cause of some forms of heart disease and stroke.

Cholesterol is the type of fat produced by the liver or from fat intake playing a critical role in the building of strong cell walls, production of vitamin D and steroid hormones and bile acid to aid digestion in the small intestine.

Cholesterol produced by the liver in a healthy individual is returned to the liver by high-density lipoprotein (HDL).

The healthy ratio of HDL/LDL cholesterol is any numbers that are less than 1/4.

On the other hand, triglyceride is fat in the blood that comes from the outside source used by the body to convert to energy.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

Triglyceride is stored in the fat cells used to produced energy between meals and in the case when food is scarce.

Compared to cholesterol, triglycerides in high levels also associated with the risk of heart disease, particularly in people with high levels of LDL and low levels of HDL.

On finding a potential phytochemical for the treatment of diseases associated with high blood cholesterol, researchers examined the Omega 3 fatty acid activity in the management of hypertriglyceridemia.

According to the results of the study,
* Omega 3 fatty acids lowered LDL cholesterol and reduce CV risk.

* Omega 3 fatty acid also lowered triglyceride (TG) levels and elevated the high-density lipoprotein (HDL) cholesterol levels.

* Omega3 fatty acid inhibited the elevated TG levels that increased risk of CV events and very high TG levels are associated with acute pancreatitis.

Collectively, researchers said, " This review focuses on the clinical practice guidelines for the management of hypertriglyceridemia and the role of prescription omega-3 fatty acids in preventing pancreatitis and CV disease in individuals with high and very high TG levels".

Taken altogether, Omega-3 fatty acids may be considered a functional food for the prevention and treatment of dyslipidemia, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(2) A Review of Clinical Practice Guidelines for the Management of Hypertriglyceridemia: A Focus on High Dose Omega-3 Fatty Acids by Karalis DG. (PubMed)

Wednesday, 22 April 2020

Herbal Angelica Reduces Myocardial Infarction Damage

By Kyle J. Norton

Myocardial infarction is a severe and medical emergency characterized by the obstruction of the blood supply to the brain, causing a stroke. Prompt treatment can minimize brain damage and potential post disease complications.

The occurrence and extent of brain infarction are associated with three basic factors, including the site of arterial occlusion, the rapidity of arterial occlusion, and the presence or absence of collateral circulation.

In other words, brain infarction can be classified into myocardial infarction due to plaque rupture and myocardial oxygen supply-demand imbalance secondary to other acute illnesses.

Stroke is caused by the accumulation of plaques or blood clots that build up the arterial walls.  In other words, if plaques or blood clots building up in the arteries is blocking the circulation of blood in any part of the body causing oxygen not to be delivered to the brain, leading to the death of some cells in the brain.

According to the statistics, every year, more than 790,000 people suffer a stroke, including 600,000 of these are first attacks, and 185,000 are recurrent attacks. Most cases of stroke occur in people over the age of 65.

The exact causes of a blood clot to induce acute brain infarction are unknown. Plaques accumulation in the arteries associated with hardening and stiffing arterial walls is a leading cause of cardiovascular disease, including stroke.

The trouble with speaking and understanding, confusion, sudden numbness, weakness or paralysis in your face, arm or leg, headache and the trouble with walking are some of the most common symptoms found in patients with post-myocardial infarction.

Depending on the severity of the acute infarction, in serious cases, patients may also experience symptoms, paralysis of the face, arm or leg, trouble with seeing in one or both eyes.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a chemical ingredient for the management of post-stroke researchers examined the mechanisms of Angelica Sinensis and Angelica sinensis polysaccharide (ASP for the treatment of acute myocardial infarction (AMI).

According to the results of the analysis, A. Sinensis exerted effect on.228 major targets that regulate multiple pathways in multiple targets involved in several biological processes against AMI injury.

In vitro and in vivo, ASP significantly decreased endoplasmic reticulum (ER) stress-induced cell death both in ischemia injury rats.

Furthermore, ASP treatment reduced infarct size and preserved heart function.

ASP enhanced activating transcription factor 6 (ATF6) activity in restoring the ER function in stressed cells.

Most importantly, ASP attenuated levels of proinflammatory cytokines and maintained a balance in the oxidant/antioxidant levels against the onset of oxidative stress after AMI.

Taken altogether, Herbal Angelica may be used for the treatment of myocardial infarction, pending to larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Network pharmacology-based identification of major components of Angelicasinensis and its action mechanism for the treatment of acute myocardial infarction by Niu X1,2, Zhang J2,3, Ni J4, Wang R1,2, Zhang W5, Sun S5, Peng Y2,6, Bai M2,6, Zhang Z. (PubMed)