Cabbage Inhibits Mitochondrial Dysfunction Caused by Oxidative Stress

By Kyle J. Norton

Mitochondria are the cell that converts food molecules into the energy for the body tissues' needs. Mitochondria produce 90 percent of the energy for body functioning.

Mitochondrial dysfunction is a condition affecting the organelles that generate energy for the cell.

The genetic proposition has been found to alter the process of mitochondria in converting oxygen and food to energy in some people. Acquired mitochondrial dysfunction has been found in patients with Alzheimer’s disease, muscular dystrophy, Lou Gehrig’s disease, diabetes, and cancer.

Acquired mitochondrial dysfunction caused by the long-term use of certain medications such as Metformin, medical conditions such as mitochondrial encephalomyopathy or infection and environmental influences, such as xenochemicals, can lead to less and less energy generated within the cells.

Most common symptoms of mitochondrial dysfunction include poor growth
muscle weakness, muscle pain, low muscle tone, exercise intolerance, vision and/or hearing problems
learning disabilities, delays in development, mental retardation depending on the location of the infected cells.

Diseases associated with mitochondrial dysfunction include Autism, autism-like features Heart, liver or kidney diseases, gastrointestinal disorders, diabetes, neurological problems, thyroid and respiratory (breathing) problems and dementia. 

Conventionally, treatments of mitochondrial dysfunction are totally depending on the causes of the disease.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.

With an aim to find natural food for the protection of mitochondrial function, researchers examined the effects of cabbage extract on oxidative stress in H9c2 cardiomyoblasts.
According to the tested differentiation,
* Cabbage extract protected against H2O2-induced cell death and did not elicit any cytotoxic effects.

* Cabbage extract suppressed ROS production and increased expression of antioxidant proteins (SOD-1, catalase, and GPx).

* Cabbage extract also inhibited apoptotic responses and activation of MAPK proteins (ERK1/2, JNK, and p-38) in oxidative stress-exposed H9c2 cells.

Precisely, cabbage extract preserved mitochondrial functions upon oxidative stress.

Taken altogether, cabbage may be considered a remedy for the protection of mitochondrial dysfunction, pending to the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cabbage (Brassica oleracea var. capitata) Protects against H2O2-Induced Oxidative Stress by Preventing Mitochondrial Dysfunction in H9c2Cardiomyoblasts by Yang DK. (PubMed)

Angelica Sinensis In the Treatment of Mammary Gland Hyperplasia in Vivo

By Kyle J. Norton

Mammary gland hyperplasia or hyperplasia of the breast is the benign overgrowth of mammary ductal epithelial cells and interstitial fibers.

Believe it or not, patients with mammary gland hyperplasia are found in 99.3% of the total patients with breast-related diseases, in which 5–10% have the potential to develop breast cancer.

Hyperplasia is the enlargement organ or tissue caused by an increase in the reproduction rate of its cells.

Hyperplasia of the breast is considered an early stage of breast cancer.

According to the statistics, atypical ductal hyperplasia (ADH) is the common form of hyperplasia of the breast found in about 5% to 20% of the diseases.

Although atypical ductal hyperplasia (ADH) is benign, the progression of the condition has been found to induce ductal carcinoma in situ (DCIS) and invasive carcinoma.

Mammary gland hyperplasia doesn't cause symptoms, However, some patients may experience a lump or pain.

Conventionally, most cases of mammary gland hyperplasia are treated by surgery that removes the abnormal cell growth.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a natural compound for the treatment of diseases associated with the breast, researchers examined the effect of acupuncture combined with medication (Rule Granule) on mammary gland hyperplasia in an animal model.

A total of 55 female SD rats were randomized into blank control group (n＝10), model group (n＝10), acupuncture group (n＝11), medication group (n＝10), and acupuncture plus medication group (n＝9), as follow

* The MGH model was established by muscular injection of E2 benzoate(0.5 mg/kg, once daily for 20 days), followed by injection of P (5 mg/kg) into the lateral muscle of the hind-limb, once daily for 5 days, and the rats of the control group were treated by muscular injection of normal saline at the same site and in the same procedures.

* Acupoint group A composed of bilateral Tianzhong (SI 11), Ganshu (BL 18) and Zusanli (ST 36), and group B composed of Tanzhong (CV 17), and bilateral Wuyi (ST 15) and Hegu (LI 4) were alternatively punctured with filiform needles and stimulated swiftly by twirling the needle in each acupoint for 20－30 sec, once daily for 30 days.

* Rats of the medication group and acupuncture ＋medication group were treated by gavage of Rule Granule fluid containing Baishao (Paeonia Iactiflora Pall), Danggui (Angelica Sinensis), etc. (1.5 mL/100 g for each rat) and those of the other groups treated by gavage of distilled water (1.5 mL/100 g). The treatment was given once daily for a continuous 30 d. At the end of the experiments,

According to the results of the analysis, the hyperplasia of the mammary gland was found to improve significantly. The serum PRL and E2 contents and the expression of prolactin receptor (PRLR), estrogen receptor (ER) and progesterone receptor (PR) was significantly decreased, and the content of P was notably increased in the acupuncture, medication, and acupuncture plus medication groups relevant to the model group.

Furthermore, acupuncture plus medication were significantly superior to those of both simple medication and simple acupuncture in down-regulating serum PRL and E2 contents and PRLR, ER and PR immunoactivity, as well as in up-regulating serum P content.

Additionally, no significant differences were found between the medication and acupuncture groups. 

Based on the findings, researchers said, "The therapeutic effects of acupuncture plus Rule Granule are better than those of simple acupuncture and simple Rule Granule".

Taken altogether, Herbal Angelica used a combination with other herbal medicine and acupuncture
for the treatment of mammary gland hyperplasia, pending to larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) [Effect of Acupuncture Combined with Gavage of Rule Granule on Serum Prolactin, Estradiol and Progestone Contents and Their Receptor Expression in Breast in Mammary Gland Hyperplasia Rats].[Article in Chinese] by Zhao X1, Qiao D2, Hou M. (PubMed)

Cleaver(Galium aparine) Protects the Cells of Thymus Against Alternation of DNA in Vivo

By Kyle J. Norton

The thymus is a small, irregular-shaped gland in the top part of the chest, just under the breastbone and between the lungs.

The thymus formed part of both the lymphatic system and the endocrine system plays a critical role in the development of T-lymphocytes or T cells, in the immune system through the production of hormones

Unlike most organs, the thymus at its largest in children. Once the children reach puberty, the thymus starts to slowly shrink and replaced by fat.

The most common diseases associated with thymus are myasthenia gravis (MG), pure red cell aplasia (PRCA) and hypogammaglobulinemia.

In other words, the myasthenia gravis is a condition caused by abnormally large thymus that produces antibodies that block or destroy the muscles' receptor sites.

The most common symptoms of thymus gland dysfunction are shortness of breath, cough, chest pain, trouble swallowing, loss of appetite and weight loss, headaches, swelling of head face or neck, a bluish color to the skin and dizziness, according to the American Cancer Society.

Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.

Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.

However, at the advanced stage, cancerous cells can travel a distance away from the original site to induce secondary metastasis.

According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.

The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.

Thymoma and thymic cancer are medical conditions associated with malignant cells form on the outside surface of the thymus due to the alternative of cell DNA.

According to statistics, thymoma is uncommon and occurs in less than 1 person per 1.5 million people develops thymoma. In other words, about 400 Americans suffer from the development of thymoma each year.

Cleaver is a herbaceous annual plant, genus Galium, belonging to the family Rubiaceae, native to North America and Eurasia. The herb has been used over thousands of years in herbal and traditional medicine as mild diuretic and blood and lymphatic cleanser and to treat psoriasis, skin conditions, glands, tonsillitis, bladder infections, prevent small kidney stone, etc.

On finding a potential compound for the treatment of cancer, researchers investigated hot component Diosmetin (DGVL) extracted from the traditional Chinese herb Galium verum L. on the thymus of U14-bearing mice.

According to the tested analysis,

* DGVL inhibited tumor growth and significantly increased the thymus weight compared to control.

* DGVL elevated serum levels of IL-2 and significantly reduced levels of TNF-α, TGF-β1, and IL-10 in a dose-dependent manner. 

In other words, DGVL protected the thymus tissues by increasing the anti-inflammatory and decreasing the pro-inflammatory expressions.

* DGVL protected thymus tissue against the proliferation of the tumor growth by inhibiting thymus lymphocyte apoptosis.

* Furthermore, the ratio of CD4(+)/CD8(+) T lymphocytes was significantly increased from 0.69 to 2.29 by treatment with DGVL, observed by the strong immune function.

* The expression of healthy cell death (Fas and FasL) on the thymus was lower in the DGVL treatment group compared to control.

Based on the findings, researchers said, " DGVL can inhibit tumor growth and protect tumor-induced apoptosis of the thymus, and the mechanism is closely associated with reduced cell death in the thymus and a Fas-FasL-dependent pathway".

Taken altogether, herbal cleaver used combination with other herbal medicines may be considered an anti thymus tumor remedy, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective effects of diosmetin extracted from Galium verum L. on the thymus of U14-bearing mice by Zhao R1, Chen Z, Jia G, Li J, Cai Y, Shao X. (PubMed)

#Healthy Food Common Fig or Fig (Ficus carica) Processes Antiviral Activities in Vitro

By Kyle J. Norton

Unlike bacteria, a virus replicates only inside the living cells of an organism. Viruses can infect all types of life forms, including humans and microorganisms, such as bacteria and archaea.

In other words, viruses are made up of a piece of genetic material, such as DNA or RNA enclosed in a coat of protein. Virtual infection is a result of a viral invasion that uses components of invaded cells to multiply, leading to the damages or alternation of the DNA or RNA of the host cells.

Anti-viral effects are the use of certain substances to cause the destruction of a virus.

In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells. The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, will attack the white blood cells of the immune system,

The viral infection has been known to carry over some different stages. After successfully attaching to the host cell, the virus releases its mRNA into the host cell, leading to the recruit of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.

The white blood cells in the systematic immune response in the acute phase of infection stimulate the production of the proinflammatory cytokines to the site of infection with an aim to protect our body by killing off the invaders.


The battle between the immune white blood cell and viral invaders in most cases is in the flavor of the immune system, leading of the death of invaders and healing of the infection.


However, if the immune system can not kill off the invaders with 3 - 8 weeks, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.

According to the statistics provided by the CDC, infectious diseases cause over 15 million visits to physician offices and 3.7 million visits to the emergency department in the US every year.

Fig is a species of F. Carica, belongings to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.

On finding natural compounds for the treatment of infectious diseases, researchers examined the latex of fig fruit (Ficus carica) on skin infections with the possible viral origin.

According to the tested differentiation of 5 extracts (methanolic, hexanoic, ethyl acetate, hexane-ethyl acetate (v/v) and chloroformic) for their antiviral potential activity against herpes simplex type 1 (HSV-1), echovirus type 11 (ECV-11) and adenovirus (ADV) in vitro, the hexanoic and hexane-ethyl acetate (v/v) extracts inhibited multiplication of viruses at concentrations of 78 µg mL(-1).

Furthermore, these two extracts were possible candidates as herbal medicines for herpes virus, echovirus, and adenovirus infectious diseases.

Most importantly, all extracts had no cytotoxic effect on Vero cells at all tested concentrations.

Taken altogether, common fig or fig (Ficus carica)  may be considered a remedy for the prevention and treatment of viral infection, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) In vitro cytotoxic and antiviral activities of Ficus carica latex extracts by Lazreg Aref H1, Gaaliche B, Fekih A, Mars M, Aouni M, Pierre Chaumon J, Said K. (PubMed)

Phytochemical Tocopherols Kill Acute Myeloid Leukemia Cells in Vitro

By Kyle J. Norton

Leukemia is a condition characterized by an abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.

Bone marrow is soft tissue inside the hollow center of the major bone. including spine, pelvis, underarm, leg. etc.

Acute leukemia is a condition caused by a rapid increase in the numbers of extreme immature white blood cells that appear in the bloodstream in the other parts of the body, including tissue and organs.

 Acute leukemia can also be classified into
* Acute lymphoblastic leukemia (ALL)
Acute lymphocytic leukemia (ALL) is a type of cancer with the abnormal growth of extreme immature lymphocytes overproduced by the bone marrow and/or lymphatic system. The condition has a tendency to multiply quickly, leading to the death of normal white blood cells in the bone marrow and/or lymphatic system.

In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.

* Acute myeloid leukemia (AML)
Acute myelogenous leukemia (AML) is a cancer of myelogenous lining caused by the rapid growth of abnormal granulocytes accumulated in the bone marrow, interfering with the normal blood cells. In AML, granulocytes appear immature in the bloodstream.

According to the statistics, in 2019, approximately 21,450 people of all ages including 11,650 men and boys and 9,800 women and girls) in the United States will be diagnosed with AML.

AML is the second most common type of leukemia diagnosed in adults and children, but most cases occur in adults. AML makes up 32% of all adult leukemia cases.

The 5-year survival rate for people 20 and older with AML is approximately 24%. For people younger than 20, the survival rate is 67%.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.


On finding a potential phytochemical for the treatment of leukemia, researchers examined the effect of δ-tocopherol in acute myeloid leukemia.

Compared to other leukemia cell lines, δ-T as low as 20 µM showed a strong activity on AML cell line KG-1.

The δ-T inhibition of AML cell line KG-1 was observed in a set of primary cells collected from patients newly diagnosed with AML.

Furthermore, δ-T also induced apoptosis and cell cycle arrest against KG-1 cells.

The results of δ-T anti-AML activity were attributed to the inhibition of protein cyclin-d1 associated with the G1 phase of the cell cycle arrest and a set of homeobox proteins associated with cancer cell growth and apoptosis.

Taken altogether, tocopherols may be considered a supplement for the prevention and treatment of acute myeloid leukemia pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Reduction in Cell Viability and in Homeobox Protein Levels Following in Vitro Exposure to δ-tocopherol in Acute Myeloid Leukemia by Collins J1, Safah H2, Lobelle-Rich P2, Whaley S3, Campbell S3, Saba NS. (PubMed)

Cruciferous Vegetables Inhibit the Risk and Progression of Prostate Cancer

By Kyle J. Norton

Cancer is a class of diseases characterized by abnormal cell growth of cells caused by the alternation of prostate cell DNA.

Prostate gland wrapped around the around a tube (the urethra), is a gland of the male reproductive system found in front of the rectum and just below the bladder with a function that produces some of the semen that carries sperm.

Prostate cancer is cancer originating from the inner lining of the prostate gland caused by irregular prostate cell growth. Prostate cancer is slow-growing cancer. However, they can be deadly in the advanced stage by traveling a distance away to infect other healthy tissue and organs.

Most prostate cancers are found in the yearly annual physical exam, designed for the male at a higher risk of prostate cancer.

The exact causes of prostate cancer are unknown. However, the most common risk factor associated with the onset of the disease is genetic mutation inherited from the parents. mutation of BRCA1 and BRCA2 reserves the function of tumor suppressor genes which normally repair mistakes in a cell's DNA to allow DNA mutation of the prostate cells.

According to the statistic provided by the American Cancer Society, 1 in 9 men will be diagnosed with prostate cancer during his lifetime. Approximately, 6 cases in 10 are diagnosed in men aged 65 or older.

The most common symptoms of prostate cancer include frequent urination, weak or interrupted urine flow or the need to strain to empty the bladder. and the urge to urine frequently at night due to the large size of the tumor that suppresses the bladder and the flow of urine.

Some patients may also experience symptoms of blood in the urine, blood in the seminal fluid and pain or burning during urination caused by the tumor that breaks the nearby small veins and nerve cells.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding potential and natural foods that process anti-cancer property, researchers investigated the protective effect of sulforaphane (SFN), an isothiocyanate (ITC) derived from cruciferous vegetables against the prostate cancers.

According to the tested analysis,
* SF exerted a strong antioxidative and chemopreventive activity by delaying or blocking carcinogenesis, in vivo.

* SF induced biochemical and epigenetic changes, preventing, delaying, or reversing preneoplastic or advanced prostate lesions, associated with the risk of cancer developing through increasing the expression of antioxidant protein NRF2.

* SF activity networks involved in cell death programming through ceratin intrinsic methods of apoptosis by causing cell cycle arrest, mitosis interruption, activation of caspases and mitochondria depolarization.

Based on the evidence, researchers said, "These outcomes encourage the consumption of Brassica specimens, which could be easily achieved by the incorporation of food and vegetables rich in cruciferous isothiocyanates in the diet".

Taken altogether, dietary cruciferous vegetables may be considered functional remedies for the protection of the prostate against cancer, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1)

Cruciferous Vegetables as Antioxidative, Chemopreventive and Antineoplasic Functional Foods: Preclinical and Clinical Evidences of Sulforaphane Against Prostate Cancers by Ferreira PMP1, Rodrigues LARL2, de Alencar Carnib LP2, de Lima Sousa PV2, Nolasco Lugo LM2, Nunes NMF1, do Nascimento Silva J1, da Silva Araûjo L3, de Macêdo Gonçalves Frota K2. (PubMed)

Turmeric, the Best Antioxidant Functional Remedy

By Kyle J. Norton

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

Antioxidants keep our bodies functioning properly by reducing the risk of diseases associated with oxidative stress.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.

Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.

This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.

Oxidative stress is a result of an imbalance of the ratio of free radicals and antioxidants in the body.

The expression of oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.

In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

In the urgency to discover a natural ingredient for the prevention and treatment of diseases associated with oxidative stress, researchers examined the effects of curcumin supplementation on oxidative stress and antioxidant defense enzymes in human subjects.

The meta-analysis reviewing the randomized controlled trials published in English in any year in Pubmed, Embase, Cochrane Central, Scopus, and Google Scholar, compared the treatment of curcumin to either placebo or standard of care or no intervention.

According to the examing of 127 titles and abstracts identified in 17 articles, including participants, ranged from 22 to 160 across the included studies, curcumin significantly reduced oxidative stress markers MDA, and increased superoxide dismutase, catalase,, and glutathione peroxidase, compared to control.

Furthermore, in subgroup analyses, curcumin could significantly reduce MDA levels with or without use of piperine, compared to only increase the SOD level in presence of piperine.

Based on the results, researchers said, "The administration of piperine with curcumin may enhance the efficacy of curcumin on antioxidant defense system".

Taken altogether, turmeric processed a high amount of bioactive compound curcumin may be considered supplements to enhance the levels of antioxidants in the host, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin reduces malondialdehyde and improves antioxidants in humans with diseased conditions: a comprehensive meta-analysis of randomized controlled trials by Alizadeh M1, Kheirouri S. (PubMed)