Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Saturday, 13 July 2019

Collard Greens, the Health Promotion Remedy

By Kyle J. Norton

Collard Greens is considered a functional food that promotes publish health against heart disease and cancer.

The heart formed part of the circulatory system is a muscular organ pumping blood through the blood vessels to nourish the cells, tissues, and organs of the body.

Heart disease is a class of condition associated with reduced function of the heart due to damage of the structure, including the heart muscle.

According to the statistics provided by the CDC, in the US, over 60 million Americans are living with some forms of heart disease. Every year about 735,000 Americans have a heart attack, including 525,000 of first heart attack and 210,000 of a recurrent heart attack.

Believe it or not, heart disease is a leading cause of death in the US, accounting for 1 in every 4 deaths.

Cancer is a group of medical and chronic conditions caused by irregular cell growth in the tissue of a specific organ due to the alternation of cell DNA.

Most cases of invasive cancer start in the cell on the surface of the inner lining of specific gland and organ before proliferating to deeper layer to form a tumor.

The National Cancer Institute, In 2018, over 1,735,000 new cases of cancer were diagnosed in the United States. The disease also causes the death of over 609,000 of Americans in the same year.

Some researchers suggested the increased risk of heart disease and cancer in the US over the past few decades may be correlated to the promotion of a high-fat diet that causes the incidence of obesity.

Dr. Ryan J. Koene, the lead scientist said, "CVD and cancer possess various similarities and possible interactions, including a number of similar risk factors (e.g. obesity, diabetes), suggesting shared biology for which there is emerging evidence".

And, "While chronic inflammation is an indispensable feature of the pathogenesis and progression of both CVD and cancer, additional mechanisms can be found at their intersection".

Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.

With an aim to find a potent and natural compound for the prevention of heart disease, researchers examined the effect of collard greens on lowering recirculation of bile acids and health promotion in the utilization of cholesterol to synthesize bile acid and reduced fat absorption.

Eight replicate incubations in the study included a substrate only, a bile acid mixture only, and 6 with the substrate and bile acid mixture were compared to Cholestyramine (a cholesterol-lowering, bile acid-binding drug) as positive control treatment and cellulose as the negative control.

Compared to the Cholestyramine collard greens, showed a 13% bile acid-binding on dry matter basis.

Furthermore, collard greens demonstrated a health-promoting potential far better than those of other testing vegetables including kale and Brussel sprout.

Moreover, steam cooking collard greens also exerted a significant improvement in vitro bile acid-binding activity.

Based on the findings, researchers after taking other factors into account wrote, "Inclusion of steam-cooked collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage in our daily diet as health-promoting vegetables should be emphasized".

In other words, regular and daily consumption of green/leafy vegetables, particularly in steam cooking, would lower the risk of chronic diseases such as cardiovascular disease and cancer, and improve public health.

Taken altogether, collard green may be considered a functional food for the promotion of overall health, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage by Kahlon TS1, Chiu MC, Chapman MH. (PubMed)
(2) Shared Risk Factors in Cardiovascular Disease and Cancer by Ryan J. Koene, MD,1 Anna E. Prizment, PhD,2,4 Anne Blaes, MD, MS,3 and Suma H. Konety, MD, MS. (PubMed)

Bromelain Improves the Neurological Status in Post Acute Infarction

By Kyle J. Norton

Acute brain infarction is the medical condition characterized by the obstruction of the blood supply to the brain, causing local death of the brain tissue.

The occurrence and extent of brain infarction are asscoaited with three basic factors, including the site of arterial occlusion, the rapidity of arterial occlusion, and the presence or absence of collateral circulation.

In other words, brain infarction can be classified into myocardial infarction due to plaque rupture and myocardial oxygen supply-demand imbalance secondary to other acute illnesses.

Most common symptoms of acute brain infarction are trouble with speaking and understanding, confusion, sudden numbness, weakness or paralysis in your face, arm or leg, headache and the trouble with walking.

Depending on the severity of the acute infarction, in serious cases, patients may also experience symptoms, paralysis of the face, arm or leg, trouble with seeing in one or both eyes.

Acute brain infarction is a medical emergency, Prompt treatment can minimize brain damage and potential complications.

There are many factors associated with the risk of acute infarction. However, aging may have a strong and negative implication on acute infarction.

Dr. Mehta RH, the lead scientist wrote, "Older age was associated with a greater proportion of patients with functional limitations, heart failure, prior coronary disease, and renal insufficiency and a lower proportion of male and diabetic patients".

And, "...age-associated differences in clinical characteristics in elderly patients with acute myocardial infarction (AMI), which account for some of the age-associated differences in mortality".

Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

On finding a potential compound for the treatment of complications after acute brain infarction, researchers examined the effect of Flogensim on the neurological status on 1st and 7 days after developing the disease.109 patients.

Where Flogenzim consists of highly active proteolytic enzymes containing bromelain, trypsin and of Rutinum.

According to the tested analysis, on day 7, Flogenzim treatment group showed a decrease in the concentration of I1-6, compared to control.

Where high levels of interleukin-6 (I1-6) is associated with postischemic inflammation in patients with acute brain infarction.

Furthermore, on day 21 among patients pertaining to a different group, the considerable difference in consequences were better increases in the treatment group.

More profoundly, the number of patients of Flogenzim group showed no dynamic or even worsening in neurological status decreases, compared to control.

Taken altogether, bromelain used alone or combined with other remedies may be considered a remedy for the improvement of neurological status, pending to the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Sources
(1) [Effect of flogensim in the treatment of postischemic inflammation (according to results of using interleukin-6 in patients with acute brain infarction)].[Article in Ukrainian] by Vinychuk SM, Cheren'ko TM. (PubMed)
(2) Acute myocardial infarction in the elderly: differences by age by Mehta RH1, Rathore SS, Radford MJ, Wang Y, Wang Y, Krumholz HM. (PubMed)

Herbal Bilberry, the Best for the treatment of Eczema with No Side Effects

By Kyle J. Norton

Eczema is a condition of inflammation caused by the damage to the epidermis, the outer layer of the skin, leading to skin dryness, flaking, erythema, infection, blistering, and cracking.

Most common symptoms of eczema include redness, itching, and the outbreak of lesions. If you experience some of the above symptoms, you may have eczema.

Eczema may be caused by a number of factors, including skin irritants induced by wool or synthetic clothing, soaps or detergents, cosmetics or perfumes, dust/sand, chemical solvents. extremes in temperatures, allergens such as plant pollen, molds, and animal dander.

Although the condition has been found in all ages, infant and children are at a greater risk for the onset of the disease.

In other words, most people have some of the aforementioned risk factors have never developed eczema.

According to the statistics, eczema has been found to affect approximately 17.8 million persons in the United States, a leading cause of morbidity compared to other conditions.

Most cases of atopic eczema are treated with the primary pharmacologic topical corticosteroids. If you use one of the above medicines, please make sure you know all the side effects for preventive measure.

Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.

With an aim to discover a natural compound or whole food for the treatment of erythematous eczema with no side effects, researchers compared the activity between a formulation of Vaccinium myrtillusseed oil, which is an effective local treatment for psoriatic lesions and BA formulation (containing Bosexil(®), INCI [International Nomenclature of Cosmetic Ingredients]: lecithin, Boswellia serrata resin extract).

Patients with erythematous eczema selected to the study were randomly assigned, in a 1:1:1 ratio, to Bosexil(®), V. myrtillus seed oil, or placebo. Changes in erythema were analyzed for.also calculated.based on the severity index scores in the eczema area.

Administration of both Bosexil(®) and the V. myrtillus seed oil showed a significant improvement compared to the placebo group.

In patients with eczema, V. myrtillus seed oil improved erythema in 77.8% of patients, compared to only 50% of cases in Bosexil(®).

Compared to no effect in patients in the placebo group with 10%, accompanied by the remaining 10% worsened erythema, V. myrtillus seed oil treatment did not induce any case of worsening, similar to those of Bosexil(®).

In other words, bilberry seed oil protected the skin against acute and chronic inflammatory skin condition, without causing any side effect when it is used as a topical agent.

The efficacy of the essential oil probably associated with various bioactive compounds, especially the anthocyanin.

Dr. Togni S the lead scientist said, "A topical formulation of Bosexil(®) may be promising for the treatment of psoriasis and erythematous eczema. Long-term studies are recommended to evaluate the adherence to this topical treatment and its clinical benefits in real life".

Taken altogether, bilberry seed oil may be considered a functioning remedy for the improvement of erythematous eczema, pending to the validation of larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) A cosmeceutical formulation based on boswellic acids for the treatment of erythematous eczema and psoriasis by Togni S1, Maramaldi G1, Di Pierro F2, Biondi M. (PubMed)

Healthy Food Onion Block Cancer Cells Proliferation

By Kyle J. Norton

Proliferation is a process of cancer growth associated with an abnormally high rate of cancer cells division, leading to rapid overgrowth of the tumor.

Cancer is a class of medical condition caused by irregular cell growth that starts in the cell on the surface of the inner lining tissue in a specific organ.

Most cancers that grow in size through proliferation can be invasive. In other words, after passing the stages of colonizing the entire tissues of the organ, invasive cancer cells can travel a distance away from the primary site in infect other healthy tissue and organ via blood and fluid circulation, leading to secondary metastasis.

Cancer cell proliferation by dividing unlimitedly, compared to normal cells that die after a certain cell cycle division.

More precisely,
* The growth of normal cells
Under normal circumstance, cell growth is a natural process without even notice, every day millions of cell grow to replace millions of dead cells and to keep our body in balance and healthy.
Sometimes, acceleration of cells growth is necessary to prevent further damage to the body organ, such as cut, injure, etc., but after fulfilling their purposes, the growth of cells are back to a normal rate again due to our body growth inhibitors. Unfortunately, skin cells sometimes overgrow while healing, leading to scar to the skin.

*The primary tumor; size and growth
A primary tumor or original tumor that the tumor progression that yields a cancerous mass. Some cancers can begin in several places, such as lymphomas and leukemias. Most cancers can not be detected until they formed a small grape-like lump. Cancer cells need 42 doublings before it can produce enough cancer cells to cause death.

According to the statistics provided by the National Cancer Institute, In 2018, approximately 1,735,350 cases of cancer were diagnosed in the US and the disease also caused the death of 609,640 Americans.

Epidemiologically, the odds of cancer incidence is 439.2 per 100,000 men and women per year based on 2011–2015 statistics.

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

On finding a potential compound for the treatment of cancer, researchers examined the effects of ethyl acetate extract of onion (EEO) had potent inhibitory effects on FAS gene involved in the over-expressing human breast cancer MDA-MB-231 cells.

According to the tested analysis, EEO exhibited MDA-MB-231 cells. apoptosis through the inhibition of FAS, the apoptosis antigen.

Furthermore, according to the differentiation of 3T3-L1 adipocytes used in vitro model of white adipocytes, EEO also suppressed the lipid accumulation via inhibition of FAS, a condition found in obese patients.

These results strongly suggested that EEO not only prevents the risk of breast cancer in obese but also has a strong impact on the reduced risk of other types of cancer associated with the FAS gene.

Dr. Wang Y, the lead scientist wrote in the final report, "Since obesity is closely related to breast cancer and obese patients are at elevated risk of developing various cancers, these findings suggested that onion might be useful for preventing obesity-related malignancy".

Additionally, in the examination of the anticancer effects on five onion varieties grown in Ontario against human adenocarcinoma (Caco-2) cells, the University of Chinese Academy of Sciences suggested
* Onion extracts and pure extracts of flavonoids exhibit antiproliferative effects against the tested cancer cell through its major phytochemical quercetin, myricetin, and kaempferol.

* Onion varieties also exhibited antiproliferative activity similar to purified flavonoids, according to the lactate dehydrogenase (LDH) assays.

* The Safrane extracts showed the weakest antiproliferative activity compared to other variety.

Taken altogether, onion may be considered a remedy for the prevention and treatment of cancer via antiproliferative activity, pending to the confirmation of the larger sample size and multicenter human study.

Sources
(1) Inhibitory effects of onion (Allium cepa L.) extract on proliferation of cancer cells and adipocytes via inhibiting fatty acid synthase by Wang Y1, Tian WX, Ma XF. (PubMed)
(2) Antiproliferative activity of Ontario grown onions against colorectal adenocarcinoma cells by Murayyan AI1, Manohar CM1, Hayward G2, Neethirajan S. (PubMed)

Friday, 12 July 2019

Herbal Ashwagandha Destroys Colorectal Cancer Cells

By Kyle J. Norton

The bowel is divided into the small bowel (or small intestine) and the large bowel (or colon and rectum).
The large intestine formed a part of the bowel in the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.

Colorectal cancer is the chronic diseases associated with a malignant tumor in the colon or rectum that begin in the cell on the surface of the inner lining of the colon or rectum before proliferating into deeper tissues to form a tumor due to the alternation of cell DNA.

Most cases of colorectal cancer are diagnosed in developed countries, including the U.S. and Canada.

The disease also is relatively very common and slowly growing and progressing cancer with a tendency that is easy to predict.

According to the statistics provided by the American Cancer Society in 2019, approximately
101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.

Furthermore, the overall, lifetime risk colorectal cancer of developing is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.

Due to the slow growth in nature, most people with colorectal cancer do not experience any symptoms until the advanced stage.

Most common symptoms of colorectal cancer at the late stage can induce symptoms of change of bowel movement, bloody stool and persistent abdominal discomforts, such as cramps, gas or pain, accompanied by the unintended weight loss, fatigue and loss of appetite,

If you experience some of the above symptoms, please contact your doctor to rule out the possibility of colorectal cancer.

At this advanced stage, colorectal cancer cells can also travel a distance away to infect other healthy tissue and organs, leading to a second metastasis.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent ingredient for the treatment of colorectal cancer, scientists investigated the effects of Withaferin A (WA), an active steroidal lactone derived from the herbal plant Withania somnifera (Ashwagandha), on reactive oxygen species (ROS) induced colorectal cancer model.

According to the tested differentiation, withaferin A showed significant activity in inducing apoptosis and cell cycle arrest in human colon cancer cells.

ROS accumulation that causes mitochondrial dysfunction associated with a cellular network of organelles involved cancer cell progression were also eradicated by the injection of withaferin A.

In other words, withaferin A induced ROS-mediated cell cycle arrest and the expression of apoptotic proteins by promoting colorectal cancer cell death resulting in decreased mitochondrial membrane potential accompanying with mitochondrial dysfunction.

On HCT-116 and RKO cells, WA exhibited cytotoxicity in a dose-dependent manner.

Based on the findings, researchers said, " these results strongly indicated that WA directly inhibits cell growth and induces apoptosis in CRC cells through ROS-mediated mitochondrial dysfunction and c-Jun N-terminal kinases (JNKs) induced apoptosis)".

Taken altogether, Ashwagandha processed abundantly bioactive compound withaferin A may be considered a functional herb for the prevention and treatment of colorectal cancer, pending to larger sample and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Withaferin A induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cells by Xia S1, Miao Y2, Liu S. (PubMed)
(2) Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity by Choi BY1, Kim BW. (PubMed)

Herbal Turmeric Promotes the Neuron Integrity

By Kyle J. Norton

A neuron or nerve cell made of a cell body (also called soma), dendrites and an axon, is a cell in the nervous system that carries electrical impulses.

Neurons are core components of the brain, spinal cord and peripheral nerves that play an essential role to process and transmit information.

The function of neurons can be classified into 3 types

* The sensory neurons found within the nervous system that convert external stimuli from the organism's environment into internal electrical impulses. In other words, sensory neurons are activated by sensory input from the environment, including physical input of sound, touch, heat, or light.

*The motor neurons transmit impulses from the spinal cord to skeletal and smooth muscles,. In other words, motor neurons directly control all of the muscle movements.

* The interneurons connect the motor and sensory neurons. In other words, the interneurons transfer signals between sensory and motor neurons.

Most common diseases associated with neurons dysfunction are amyotrophic lateral sclerosis (ALS). Lou Gehrig's disease or classical motor neuron disease that disrupts signals to all voluntary muscles on both sides of the body.

Dr. Hui-Ming Gao, the lead scientist in the investigation of the dysfunction and death of neurons in human degenerative neurological diseases wrote, "Neurodegenerative diseases are characterized by slow progressive loss of neurons in the central nervous system (CNS), which leads to deficits in specific brain functions (e.g. memory, movement, cognition) performed by the affected CNS region.

And, "These neurodegenerative diseases include Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), multiple sclerosis, Huntington's disease, and multiple system atrophy. Neurodegenerative diseases usually extend over a decade, and the actual onset of neurodegeneration may precede clinical manifestations by many years".

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On finding a potential ingredient for the treatment of neurological cancer, researchers examined the neuroprotective effect of fermented C. longa (FCL) in two brain cell lines (rat glioma C6 and murine microglia BV2) and scopolamine-treated mice.

According to the tested differentiation, C. longa powder fermented by 5% Lactobacillus plantarum K154 containing 2% (w/v) yeast extract at 30 °C for 72 h followed by sterilization at 121 °C for 15 min, effectively prevented the cells death induced by oxidative stress in the tested C6 cells.

Furthermore, FCL inhibited the production of free radicals and proteins associated with the production of pro-inflammatory cytokines in BV2 cells.

Moreover, FCL significantly protected the neuron integrity in the hippocampus by attenuating scopolamine-induced memory impairment in mice and AChE activity associated with neuron damage.

FCL also protected the neurons against the reduction of brain-derived neurotrophic factor (BDNF) that has a strong impact on synaptic function and neuronal development and cAMP response element-binding protein (CREB) associated with long-term memory.

Based on the findings, researchers wrote, "FCL pretreatment could alleviate scopolamine-induced memory impairment in mice, as well as oxidative stress and inflammation in C6 and BV2 cells, respectively. Thus, FCL might be a useful material for preventing impairment of learning and memory".

Taken altogether, fermented turmeric may be considered supplements for the protection of the neuron integrity, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The protective effect of fermented Curcuma longa L. on memory dysfunction in oxidative stress-induced C6 gliomal cells, proinflammatory-activated BV2 microglial cells, and scopolamine-induced amnesia model in mice by Eun CS1, Lim JS2, Lee J3, Lee SP1,2, Yang SA. (PubMed)
(2) Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: towards targeting of cancer stem cells with phytochemicals by Fong D1, Yeh A, Naftalovich R, Choi TH, Chan MM. (PubMed)
(3) Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression by Hui-Ming Gao and Jau-Shyong Hong. (PMC)

Healthy Legume Navy Bean Promotes Gut Digestibility

By Kyle J. Norton

Digestibility is a process that a percentage of foods absorbed by the body after intake by an individual.

On the other hand, digestion is the process that breaks down broken down into nutrients through both mechanical and chemical digestion.

The digestive system consists of the gastrointestinal tract and organs of digestion, including the tongue, salivary glands, pancreas, liver, and gallbladder.

The digestive system plays a critical role in maintaining the proper function of the body involved in the breakdown of food into smaller and smaller components before being absorbed and assimilated into the body.

The digestive disorder is medical conditions that affect the function of the digestive tract, including heartburn/GERD, IBD, and IBS that orchestrate symptoms of bloating, diarrhea, gas, stomach pain, and stomach cramps.

Although there are many prevalent factors that cause the onset of digestive disorder, some researchers suggested that the imbalanced gut microbiota may be one of the major culprits that elevate the risk of the disease.

Dr. Caitriona M. Guinane, the lead scientist wrote, "The human gut microbiota has become the subject of extensive research in recent years and our knowledge of the resident species and their potential functional capacity is rapidly growing".

And, "the resident microbiota influence host metabolism, physiology, and immune system development while perturbation of the microbial community can result in chronic GI disease.".

The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to their numerous health benefits.

On finding potential health food which enhances the digestive function, researchers examined the total tract digestibility and safety of cooked navy bean powder when incorporated into a canine diet formulation at 25% (wt/wt).

The randomized, blinded, placebo-controlled for a 28-d dietary intervention study included 21 healthy, free-living, male and female adult dogs of different breeds.

In the comparison of the apparent total tract energy and nutrient digestibility of the navy bean powder diet with the control diet, researchers found that

* Digestibilities and metabolizable energy (ME) content were 68.58 and 68.89% dry matter (DM), 78.22 and 79.49% crude protein (CP), 77.57 and 74.91% organic matter (OM), 94.49 and 93.85% acid-hydrolyzed fat, and 3,313 and 3,195 kcal ME/kg for the navy bean diet and control diet, respectively.)

* There are no differences observed between the groups, particularly in those of flatulence or major change in fecal consistency.

* Navy bean powder at 25% (wt/wt) of total diet was found to be palatable and digestible in tested animals.

Based on the finding and after taking other factors such as complete blood counts, blood biochemical profiles into the account, researchers wrote, "cooked navy bean powder can be safely included as a major food ingredient in canine diet formulations and provide a novel quality protein source,....for chronic disease control and prevention".

Taken altogether, the cooked navy bean processes total tract digestibility that can be used for the prevention and treatment of chronic diseases, pending to the confirmation of the larger sample size and multicenter human study.

Sources
(1) Effects of cooked navy bean powder on apparent total tract nutrient digestibility and safety in healthy adult dogs by Forster GM1, Hill D, Gregory G, Weishaar KM, Lana S, Bauer JE, Ryan EP. (PubMed)
(2) Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ by Caitriona M. Guinane and Paul D. Cotter. (PMC)