Monday, 26 February 2018

Herbal Therapy: Anise in Reduced Risk, Progression and Treatment of Gastric Ulcers

Kyle J. Norton


Anise may have a potential and substantial effect in reduced risk and progression and treatment of gastric ulcers, some scientists suggested.

Anise is a flowering plant ofthe species of Pimpinella anisum, genus Pimpinella, belongings to the family Apiaceae native to to Egypt and the Mediterranean region, used in traditional herbal medicine as fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic, ....


Chemical comstituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.

In the evaluate the claim of Unani and Arabian traditional medicine practitioners on the gastroprotective potential effect by using 80% ethanol, 0.2 mol/L NaOH, 25% NaCl and indomethacininduced gastric ulceration and secretion in rat model, researhcers found that application of doses of 250 and 500 mg/kg body weight of Anise exert a significant protective activity against basal gastric acid secretion, acidity and completely inhibited the rumenal ulceration caused by necrotizing agents, by initiating production of depleted levels of gastric mucosal NP-SH and gastric wall mucus concentration.

Further analysis suggested that the anti gastric ulcers of Anise suspension was attributed the herbal medicine antioxidants in enhnaced production of hormone prostaglandins in inhibited levels of gastric secretion.

The hormone has been study intensively for protection and treatment of gastric ulcer by some scientists due to its effect in promoted rapid restitution of the superficial epithelium of the gastric mucosa and preservation of the deeper layers through the ability of the hormones in inhibited gastric secretion, stimulated bicarbonate secretion, and increased gastric blood volume.

According to Dr. Wilson DE, "Orally administered prostaglandin analogues have been helpful in some patients who failed to heal with standard ulcer treatment and in smokers, who usually do not heal as well as nonsmokers".

Some researchers suggested that the prostaglandin analogues may be an ideal solution of patient who are at high risk for gastric lesions due to chronic consumers of nonsteroidal antiinflammatory drugs or alcohol.

Moreover, in the investigation of the effect of essential oil isolated from Croton zehntneri (EOCZ), a plant native to northeastern Brazil and anethole at doses of 30–300 mg/kg, researchers found that the composition demonstrated a strongly and linearly gastroprotective effect against ethanol- and indomethacin-induced gastric damage without changing to cold-restraint stress-induced ulcers in rats.

According to the measurement by Alcian blue binding assay, EOCZ and anethole (both at 30 and 300 mg/kg) similarly and significantly increased the mucus production by the gastric mucosa.

Additionally, the composition also consisted a significant effect on the volume of gastric juice, pH, or total acidity through its ability of EOCZ and anethole in enhanced production of gastric wall mucus.

The above of differentiation were supported by the study to test the major bioactive compound anethole effect in the ethanol-induced ulcer model in mice conducted by the joint investagation lead by Coordenação do Curso de Farmácia,

According to the results, after taking into account of other co founders, application of anethole (300 mg/kg) increased the level of gastric mucus, while derivatives (300 mg/kg) showed gastroprotective activity without affecting mucus secretion, through anethole antioxidant and anti inflammation activities.

By examining the antioxidant aspects in the experiment mice, researchers surprisingly found that anethole exhibited protective gastric effect through reduced oxidative stress caused by induced suspension in activated the gastric mucosal nitric oxide (NO) in maintaining gastric mucosal integrity, and improving production of the natural antioxidants in the host body, including glutathione (GSH), lipid peroxide (MDA, measured as malondialdehyde) glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase.

Importantly, anethole also reduced oxidative stress in initiated levels of proinflammatory substances of plasma tumor necrosis factor-α with function involved in systemic inflammation in the acute phase reaction and interleukin-1β and IL-6 in regulated immune response in protect the host against bacterial and viral in induction of infection.

Taken together, herbal Anise and its majors chemical constituent anethole may be considered as a secondary therapy accompanied with conventional medicine for treatment of gastric ulcer. However, intake of Anise supplement should be taken extreme care in prevention of acute liver toxicity.



For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN

Arthritis Is Curable

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Aqueous suspension of anise “Pimpinella anisum” protects rats against chemically induced gastric ulcers by Ibrahim A Al Mofleh, Abdulqader A Alhaider, Jaber S Mossa, Mohammed O Al-Soohaibani, and Syed Rafatullah(PubMed Central Canada)
(2) Prostaglandins in peptic ulcer disease. Their postulated role in the pathogenesis and treatment by Wilson DE(PubMed)
(3) Anti-Ulcer Activity of Essential Oil Constituents Francisco de Assis Oliveira 1 , Luciana Nalone Andrade 2 , Élida Batista Vieira de Sousa 3 and Damião Pergentino de Sousa(Open Access)
(3) Essential oil of Croton zehntneri and its major constituent anethole display gastroprotective effect by increasing the surface mucous layer by Andrelina N. Coelho-de-Souza, Saad Lahlou, João E.F. Barreto, Maria E.M. Yum, Ariclécio C. Oliveira, Hermógenes D. Oliveira, Nathalia R. Celedônio, Roney G.F. Feitosa, Gloria P. Duarte, Cláudia F. Santos, Aline A.C. de Albuquerque, José H. Leal-Card(Fundamental and Clinical Pharmacology)

Alternative Therapy: Yoga in Improved All Aspects in Patients with Arthritis

Kyle J. Norton

Yoga may be used as integrated form of exercise used conjunction with standard therapy for reduced symptoms and treatment of arthritis, the University of Cincinnati study suggested.

Arthritis, one of Musculoskeletal disorders (MSDs) degenerative disease, is a general term of joint inflammation, affecting over 21% of US population.

Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

Researchers at the Nursing Department, Bethesda, in the study of minor population and risk of arthritis by assigned each individual to an 8-week program of yoga classes, base on collecting patient-reported outcome measures related to spiritual growth, health responsibility, interpersonal relations, and stress management suggested that
* Minor population expressed that attending yoga classes designed for patients with arthritis, with racially concordant instructors may be the best acceptable use of yoga as an adjunct to standard arthritis treatment.
* Patients also stress that yoga may improve physical and mental well-being.
* Yoga participants may also experience positively change of physical function, anxiety/depression, fatigue, sleep disturbance, social roles, and pain.

Dr. Middleton KR, the led author said,"Adopting behaviors that improve well-being and quality of life include those that integrate mental health (mind) and physical health (body). Few studies have examined offering integrative modalities to this population".

Truly, yoga slow breathing and meditation calm the central nervous system in response to stress implication in production of stress hormone to stimulate the expression of inflammatory cytokine in precipitated symptoms of arthritis such as pain, swelling, thus alleviating physical symptoms in all aspects.

Psychologically, by relaxed the nervous system during stress also ameliorated hormone imbalanced in over production of stress hormone, such as cortisol,... sex hormones , such as estrogen and testosterone and thyroid hormone in induction of anxiety and depression as well as improved production of hormone melatonin made by the pineal gland in control awake and sleep.

Some researchers suggested that the above indications can be achieved by certain yoga postures practice as they can stimulate different parts of your body, organs, chakras, and the endocrine system in control production of hormones and functionings.

Furthermore, yoga midfulness also re connected and re balanced the mind and body, by bring back the presence while letting them, such as stress or dealing them in a profound and positive ways, leading to actively engage in healthy living and healthy live style and eating and participating in social activity.

These results showed that yoga intervention have a strong impact in alleviated both psychological and physical aspects of patients with arthritis.

The above differentiation were supported by study conducted by University of Cincinnati, in the review literature between 2010 to June 2013 to examine whether yoga can be an efficacious approach for managing arthritis from Medline, Cumulative Index to Nursing and Allied Health, and Alt HealthWatch databases.

 According to the findings of 9 studies satisfied the criteria, researchers found that
* 6 studies demonstrated the efficay of yoga in reduced both psychological or physiological symptoms related to arthritis.
* After adjusting other factors such as sample sizes, nonstandardized yoga intervention, not using behavioral theory, and having varying lengths, yoga may be used as a form of exercise in treating modality for arthritis.

And, the study of  in the review of peer-reviewed research from clinical trials (published from 1980 to 2010), using yoga as an intervention for arthritis and reported quantitative findings by the Johns Hopkins School of Public Health.

According to 11 studies selected, scientists indicated that
* Most studies provided some extend evidences in ameliorated disease symptoms, including (tender/swollen joints, pain) and disability and improved self-efficacy and mental health
* Yoga was comparable or better than that typical for exercise interventions
* After adjusting to other factors, interventions, research methods, and disease diagnoses, no adverse effects have been recorded

Taking altogether, Yoga lessons may be a best form of integrated and safe exercise for attenuated symptoms of patients with arthritis.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Yoga as an alternative and complementary approach for arthritis: a systematic review by Sharma M1.(PubMed)
(2) A pilot study of yoga as self-care for arthritis in minority communities by Middleton KR1, Ward MM, Haaz S, Velummylum S, Fike A, Acevedo AT, Tataw-Ayuketah G, Dietz L, Mittleman BB, Wallen GR.(PubMed)
(3) Yoga for arthritis: a scoping review by Haaz S1, Bartlett SJ.(PubMed)

Sunday, 25 February 2018

Food Therapy: Green tea Ameliorated Psychologically Chronic Stress by Normalizing Adrenal Dysfunction and Treatment of Fibromyalgia Caused By Stress Induced Hypo DHEA

Kyle J. Norton 

Green tea may have a therapeutic and positive effect in reduced onset, progression and treatment of fibromyalgia (FM) caused by stress, some scientists suggested.

Green tea is a precious drink processed numbers of health benefit and known to almost everyone in Asia and Western world.

Fibromyalgia (FM) is a chronic condition characterized by muscle and soft tissue pain, affecting over 10 million (3.6% of the population) people in US alone.

In the review of the existed literature in relation between fibromyalgia in a somatic response to psychological stress, researchers found that patients with the chronic illness display a numbers of abnormalities in neuroendocrine function as a result of chronic stress.

Further analysis of the hormone expression of HPA axis and sympatho-adrenal system HPA axis, along with the sympatho-adrenal system in response to the chronic stress, researchers found that HPA axis is underactive in fibromyalgia due to insufficient hypothalamus in stimulated the release corticotrophin-releasing hormone (CRH) in activation of cortisol secretion from the adrenals, caused by chronic stress.

Levels of corticotrophin-releasing hormone (CRH) was activated by the responsiveness of DHEA.

These result reaffirmed the consistent with a central abnormality of the HPA axis in fibromyalgia, resulting from the undersecretion of CRH by the hypothalamus.

In a randomized cross-over design study, 18 students (nine male and nine female) participated in three experimental trials on different days at intervals of seven days conducted by the University of Shizuoka, researchers showed that according to the differentiated Saliva collected before beverage intake and after performing the mental stress load tasks, green tea treatment group exerted a significant improvement of Total Mood Disturbance (TMD) score on the Profile of Mood States (POMS).

Moreover, green tea treatment group ameliorated the increased salivary CgA concentration levels in response to psychological and physical stress after mental stress load tasks.

Both green and white tea demonstrated a strong effect in improve performance on an arithmetic task in compared to warm water treated group.

However, green tea ingestion exerted lesser anti stress activity in compared to the consumption of white tea group.

The above differentiation were supported by the study of theanine, an amino acid in green tea anti-stress effects on animals and humans activity in examined three types of green teas, theanine-rich "Gyokuro", standard "Sencha", and Sencha with lowered caffeine (low-caffeine green tea) in mice model, conducted by the joint study lead by the joint University of Shizuoka.

According to the study, application of green tea showed a strong effect in normalized adrenal dysfunction (hyper-adrenal DHEA production), induced by chronic stress, eluted with water at room temperature.

Interestingly, researchers after taking into account of other co founders suggested that application of caffeine and tea, polyphenol EGCG suppressed the anti-stress caused by (hyper-adrenal DHEA production in this case) effects of theanine while EGC and arginine (Arg) retained these effects.

Additionally, in the investigation of green tea phytochemical epigallocatechin-3-gallate (EGCG) in alleviating age-associated aberrations in immunity, hypothalamus-pituitary-adrenal (HPA) axis in 16 months old male Swiss albino mice, rendomized assigned to four groups of animals (n = 6 per group) given supplemented with either aqueous EGCG at 25, 50 and 100 mg/kg/animal or vehicle control for 6 weeks, scientists indicated that EGCG treatment mice during aging strengthens systemic immunity by enhancing cellular immune response and simultaneously attenuating antibody response aided by increasing adrenal DHEA production(hypo-adrenal DHEA production in this case), another indication of correlation between expression of adrenal dysfunction of development of fibromyalgia.

Green tea anti chronic stress in reduced fibromyalgia caused by adrenal dysfunction was attributed to the over all effects of all chemical constituents, including the levels of theanine, EGC, arginine (Arg) and EGCG.

The findings suggested that green tea consists a significant activity in ameliorated adrenal dysfunction caused by chronic stress, particularly, in chronic stress initiated hypo-adrenal DHEA production for precipitation of fibromyalgia.

Taken together, green tea as a whole food medicine may be considered as a function food in ameliorated early onset, progression and combined with standard medicine for treatment of fibromyalgia due to long term exposure to psychological stress. However, intake of green tea supplement should be taken with extreme care due to recent reports of acute liver toxicity.


Reprint of this article is welcome with author name and link back to the home page intact https://kylejnorton.blogspot.ca

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women 


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Psychological stress and fibromyalgia: a review of the evidence suggesting a neuroendocrine link by Anindya Gupta1 and Alan J Silman(PMC)
(2) Intake of green tea inhibited increase of salivary chromogranin A after mental task stress loads by Yoto A1, Murao S, Nakamura Y, Yokogoshi H.(PubMed)
(3) Anti-stress effects of drinking green tea with lowered caffeine and enriched theanine, y epigallocatechin and arginine on psychosocial stress induced adrenal hypertrophy in mice bUnno K1, Hara A2, Nakagawa A2, Iguchi K2, Ohshio M3, Morita A3, Nakamura Y4.(PubMed)
(4) Consumption of green tea epigallocatechin-3-gallate enhances systemic immune response, antioxidative capacity and HPA axis functions in aged male swiss albino mice by Sharma R1, Sharma A2, Kumari A3, Kulurkar PM2, Raj R2, Gulati A3, Padwad YS4.(PubMed)

The Best 5 Studied Proof Foods for Reducing Risk and Treatment of Benign Prostatic Hyperplasia(BPH)

Kyle J. Norton

Benign prostatic hyperplasia(BPH) is a condition of increased numbers of cell of prostate tissues, causing partial, or sometimes virtually complete obstruction of the urinary tract.

According to statistic, BPH commonly starts at age of 30 and symptoms usually can not be realized until age of 50.

More than half of men between age of 60-70 are experience symptoms of BPH and only 10% are required treatment.

Suggestion of BPH is associated to nutritional status and eating habits, according to the study, 30 male patients with clinically confirmed and treated disease of the prostatic gland, including 15 men (aged 51-75 years) with BPH and 15 men (aged 51-73 years) with PC, indicated that improper nutritional status leaind to incorrect nutritional habits and failing to improve their health, may be the cause of the development of some diet-dependent diseases, such as BPH and prostate cancer(a).

A proper diet with vegetable, fruit containing zinc may reduce the risk of the disease from initiation(b)(c).

Epidemiological studies, indicated intake of vegetables and fruits accompanied with healthy life style may be associated in prevented risk and treatment of enlarged prostate(d)(e)(f)in inhibited over production of prostate cells though antioxidant activity (g)(h).

Top 5 Foods for Reducing Risk of Benign prostatic hyperplasia(BPH)

1. Green tea
Green tea containing more amount of antioxidants than any drinks or food with the same volume, is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China.

Green tea is a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years.

Because of their health benefits, they have been cultivated for commercial purposes all over the world.

In the examine the levels and activity of androgen hormones in associated to the risk of BPH, researchers indicated that application of green tea catechin, (-)epigallocatechin-3-gallate, modulated the expression androgenic activity in reduced progression of benign prostatic hyperplasia.

These result suggested that EGCG may be useful for the treatment of various hormone-related abnormalities, inckuding benign prostatic hyperplasia(29)(32)

5 alpha-reductase activity long has suspected to a significant impact in induction of early onset of benign prostatic hyperplasia,

According to the study conducted by the Ben May Institute for Cancer Research, and The Tang Center for Herbal Medicine Research, administration of green tea catechin (-)-epigallocatechin gallate (EGCG) exerts a strong effect in replaced the gallate ester with long-chain fatty acids in acting as a potent 5 alpha-reductase inhibitors(30).

 The study by the Oregon State University, also indicated that the combination of soy and tea attenuated prostate malignancy by decreasing prostate hyperplasia in male noble rats implanted with estradiol and testosterone(31)


2. Coffee

Coffee made from the roasted seeds of the genus Coffee, belongings to the family Rubiaceae native to southern Arabia.

According to Dr. Morrison AS. coffee drinking was inversely but only weakly related to prostatic hypertrophy(BPH) in 910 residents of Rhode Island who had a partial or total prostatectomybetween the years 1985-1987(33).

In a study of a total of 1369 patients younger than 75 years old surgically treated for BPH and 1451 controls younger than 75 years of age, the prevalence of  BPH was insignificantly among coffee drinkers(34)(35)

However, according to the study by the Univ Estadual Paulista (UNESP) in the rat prostate gland, chronic caffeine intake from puberty may increase androgenic signalling and cell proliferation in initiated development of benign prostatic hyperplasia(36).

3. Pumpkin seeds
Pumpkin seed(PS) or pepita, an edible seed of a pumpkin with flat, dark green color is the genus Cucurbita and belonging to the family Cucurbitaceae.

The origin of pumpkins is unknown, although many people believe that they have originated in North America.

According the study of 20 male Wistar rats, conducted by the Michael Okpara University of Agriculture, injection of pumpkin seeds inhibited the induction of BPH and through increasing the testosterone:estradiol ratio(37).

In a randomized, double-blind, placebo-controlled trial in over 12 months on 47 benign prostatic hyperplasia patients with average age of 53.3 years and international prostate symptom score over 8, researchers showed that PS demonstrated a positive effect in treatments of benign prostatic hyperplasia(38).

Other study also suggested that oral administration of pumpkin seed oil inhibits testosterone-induced hyperplasia of the prostate(39).

4. Coconut oil
Coconut palm tree is a genus cocos, belongings to the family Arecaceae, native to the tropic and subtropic area.
According to chemical differentiation, coconut oil may reduce total cholesterol, triglycerides, phospholipids, LDL, and VLDL cholesterol levels and increased HDL cholesterol in serum, etc through numbers of phytochemicals.(40).

Coconut oil reduced the increase of both prostate weight (PW) and body weight (BW) ratio, markers in testosterone-induced PH in rats(41).

5. Fish oil

Fish oil, rich in long-chain polyunsaturated essential fatty acids of the omega-3 group may have a potential effect in  reduced BPH risk.

According to the study by the University of California at Davis, gamma-linolenic acid (GLA) from fish oil inhibited 80% of gamDHT-enhanced activity of 5 alpha-reductase(42).

Other, in the study of the serum samples of 24 BPH and 19 PC patients, and from 21 age-matched normal male subjects, scientists found that the omega-3 PUFAs level was significantly decreased in patient with BPH(43).

However, in the study to compare the levels of n-3 polyunsaturated fatty acids (PUFAs) in leukocytes and prostate tissue in men with prostate cancer or benign prostatic hyperplasia (BPH), scientists found that long-chain polyunsaturated essential fatty acids intake is not associated in reduced risk of BPH(44).

Taking altogether, certain foods have been found effectively in reduced risk and treatments of Benign prostatic hyperplasia(BPH). But large sample and multi centers studies are necessary for reconfirm the viability.

Reprint of this article is welcome with author name and link back to the article intact  https://kylejnorton.blogspot.ca/2018/02/herbal-therapy-green-tea-and-its_24.html

Arthritis Is Curable

You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.References
(a) Nutritional status and nutritional habits of men with benign prostatic hyperplasia or prostate cancer - preliminary investigation by Goluch-Koniuszy Z, Rygielska M, Nowacka I.(PubMed)
(b) Diet and benign prostatic hyperplasia: a study in Greece by Lagiou P1, Wuu J, Trichopoulou A, Hsieh CC, Adami HO, Trichopoulos D.(PubMed)
(c) Associations of obesity, physical activity and diet with benign prostatic hyperplasia and lower urinary tract symptoms by Raheem OA1, Parsons JK.(PubMed)
(d) Nutrition and benign prostatic hyperplasia by Espinosa G.(PubMed)
(e) Dietary patterns and prostatic diseases by Sebastiano C1, Vincenzo F, Tommaso C, Giuseppe S, Marco R, Ivana C, Giorgio R, Massimo M, Giuseppe M.(PubMed)
(f) Fruit and vegetable consumption, intake of micronutrients, and benign prostatic hyperplasia in US men by Rohrmann S1, Giovannucci E, Willett WC, Platz EA.(PubMed)
(g) Evaluation of oxidative stress and DNA damage in benign prostatic hyperplasia patients and comparison with controls by Ahmad M1, Suhail N, Mansoor T, Banu N, Ahmad S(PubMed).
(h) Oxidative stress and antioxidant status in non-metastatic prostate cancer and benign prostatic hyperplasia by Aydin A1, Arsova-Sarafinovska Z, Sayal A, Eken A, Erdem O, Erten K, Ozgök Y, Dimovski A.(PubMed)
(29) The medicinal action of androgens and green tea epigallocatechin gallate by Liao S.(PubMed)
(30) Structure-activity relationships for inhibition of human 5alpha-reductases by polyphenols by Hiipakka RA1, Zhang HZ, Dai W, Dai Q, Liao S.(PubMed)
(31) Dietary soy and tea mitigate chronic inflammation and prostate cancer via NFκB pathway in the Noble rat model by Hsu A1, Bruno RS, Löhr CV, Taylor AW, Dashwood RH, Bray TM, Ho E.(PubMed)
(32) The medicinal action of androgens and green tea epigallocatechin gallate by Liao S.(PubMed)
(33) Risk factors for surgery for prostatic hypertrophy by Morrison AS.(PubMed)
(34) Food groups and risk of benign prostatic hyperplasia. by Bravi F1, Bosetti C, Dal Maso L, Talamini R, Montella M, Negri E, Ramazzotti V, Franceschi S, La Vecchia C.(PubMed)
(35) Benign prostatic hyperplasia: the opposite effects of alcohol and coffee intake by Gass R.(PubMed)
(36) Chronic caffeine intake increases androgenic stimuli, epithelial cell proliferation and hyperplasia in rat ventral prostate by Sarobo C1, Lacorte LM, Martins M, Rinaldi JC, Moroz A, Scarano WR, Delella FK, Felisbino SL.(PubMed)
(37) Inhibition of the experimental induction of benign prostatic hyperplasia: a possible role for fluted pumpkin (Telfairia occidentalis Hook f.) seeds by Ejike CE1, Ezeanyika LU.(PubMed)
(38) Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia by Hong H1, Kim CS, Maeng S.(PubMed)
(39) Inhibition of testosterone-induced hyperplasia of the prostate of sprague-dawley rats by pumpkin seed oil by Gossell-Williams M1, Davis A, O'Connor N.(PubMed)
(40) Beneficial effects of virgin coconut oil on lipid parameters and in vitro LDL oxidation. Nevin KG. Rajamohan T. Clinical Biochemistry. 37(9):830-5, 2004 Sep. [Comparative Study. Journal Article] UI: 15329324 Authors Full Name Nevin, K G. Rajamohan, T.
(41) Effects of coconut oil on testosterone-induced prostatic hyperplasia in Sprague-Dawley rats. by de Lourdes Arruzazabala M1, Molina V, Más R, Carbajal D, Marrero D, González V, Rodríguez E.(PubMed)
(42) 5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids by Pham H1, Ziboh VA.(PubMed)
(43) Comparison of fatty acid profiles in the serum of patients with prostate cancer and benign prostatic hyperplasia by Yang YJ1, Lee SH, Hong SJ, Chung BC.(PubMed)
(44) Prostate tissue and leukocyte levels of n-3 polyunsaturated fatty acids in men with benign prostate hyperplasia or prostate cancer by Christensen JH1, Fabrin K, Borup K, Barber N, Poulsen J.(PubMed)

Saturday, 24 February 2018

Herbal Therapy: Green tea and Its Polyphenols for Prevention and Treatment of Colitis

Kyle J. Norton 

Green tea may have a therapeutic and profound effect in reduced risk and treatment of colictiss, some scientists suggested.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

Colitis is a medical condition characterized by inflammation of the inner lining of the colon as a result of infection, inflammation caused by other bowel diseases.

In the comparison of the effects of green tea extract epigallocatechin-3-gallate, EGCG and
Piper nigrum (L.) alkaloid piperine in mice colitis induced by oral administration of dextran sodium sulfate randomly assigned to a daily oral administration of 6.9 mg/kg body weight EGCG or Piper nigrum (L.) piperine (2.9 mg/kg body weight) or the combination of the both with piperine used in the combination to enhance the bioavailability of EGCG and untreated controls, researchers at the Münster University Hospital showed that mice group treated with the combination demonstrate a significant effect in reduced weight loss and improved over all survival in compared to non treatment group through inducing lesser histological damages to the colon and reduction of tissue concentrations of malondialdehyde, an indication of decreased oxidative stress.

According to neutrophils accumulation assay, application of green tea EGCG and piperine displayed a strong activity in reduced ROS expression in induction of lipid peroxidation through activation of over expression of antioxidant enzymes such as superoxide dismutase(SOD) and glutathione peroxidase(GPO).

Further examining also found that the combined ingredients induced a also reduced the production of proinflammatory cytokines.

Dr. Brückner M, after taking into account of other con-founders suggested, "the concept of anti-inflammatory properties of EGCG being generally beneficial in the DSS-model of colitis".

Interestingly, in dextran sulfate sodium (DSS)-induced mouse model of colitis, application of green tea EGCG (3.2 mg/g) as a source of drinking fluid for 3 days exerted a significant effect in ameliorated of colon shortening and spleen enlargement caused by injection of DSS and modulated the production of levels inflammatory cytokines of of interleukin 1 beta (IL-1β) and
Interleukin 6 (IL-6), which play the important roles in regulation of immune and inflammatory responses to acute and chronic infections.

Further more, green tea oral administration also decreased levels of tumor necrosis factor-α, a cell signaling protein in activated systemic inflammation and pro inflammatory cytokines in acute phase of reaction and inhibited ROS expression colonic lipid peroxides through antioxidant activity.

Moreover, the bioactive polyphenol EGCG also improved the small intestinal function in reduced leaky gut, associated to risk of increase the number of harmful compounds entering the bloodstream.

Further analysis of green tea efficacy in treatment of colitis, researchers discovered that green tea EGCG also induced weight loss through binding on the surface of the small intestine in decreased protein and lipid digestion.

In additional evaluation of green tea polyphenols (GrTP, EGCG) and sulfasalazine activity in colitis induced by injection of Dextran sodium sulfate (DSS) to cause deficiency of IL-10 in BALB/c mice, researchers at the University of Kentucky, postulated that the combined administration significantly ameliorate colonic damage and histological scores in a similar manner (GrTP vs. DSS p < 0.05; EGCG, sulfasalazine vs. DSS p < 0.01) and decrease expression of the inflammatory markers TNFα (3-fold), IL-6 (14-fold) as mentioned above.

Importantly, treated mice with both green tea polyphenols (GrTP, EGCG) and sulfasalazine also expressed a huge improvement in antioxidant capacity in inhibition of ROS in initiated chain reaction to facilitate of plagues formation and inflammation, observed by activity of bio maker lectin levels.

The information findings insisted that green tea with abundantly selective bioactive polyphenols may be considered as a functional food for prevention and treatment of colitis. However, intake of green tea supplement should be taken with exceptional care as acute liver toxicity was reported in numbers of case.

Reprint of this article is welcome with author name and link to the article intact https://kylejnorton.blogspot.ca/2018/02/herbal-therapy-green-tea-and-its_24.html


For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women 


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Green tea polyphenol epigallocatechin-3-gallate shows therapeutic antioxidative effects in a murine model of colitis by Brückner M1, Westphal S, Domschke W, Kucharzik T, Lügering A.(PubMed)
(2) (-)-Epigallocatechin-3-gallate decreases colonic inflammation and permeability in a mouse model of colitis, but reduces macronutrient digestion and exacerbates weight loss by Bitzer ZT1, Elias RJ1, Vijay-Kumar M2, Lambert JD3,4.(PubMed)
(3) Green Tea Polyphenols and Sulfasalazine have Parallel Anti-Inflammatory Properties in ColitisModels by Oz HS1, Chen T, de Villiers WJ.(PubMed)

Alternative Therapy: Yoga Intervention Improved Cardiovascular Endurance, Inflammatory Markers, Flexibility and Quality of Life of Heart Failure Patients

Kyle J. Norton 


Yoga may be considered as an integrated form of exercise in improved cardiovascular endurance, inflammatory expression, flexibility and quality of life of heart failure patients, some scientists postulated.

Heart failure is a medical condition characterized by insufficiently to maintain blood flow to meet the body's needs, inducing symptoms of shortness of breath, excessive tiredness, and leg swelling.....

Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In a study of 130 heart failure patients recruited, 65 patients randomly selected to receive 12 week yoga therapy along with standard medical therapy (yoga group). Other patients (n=65) received only standard medical therapy (control group), researchers showed that
* Yoga group expressed a enormous improvement in decrease in heart rate, blood pressure and rate pressure product (RPP)in compared to control group
* All heart rate ratio and variability were improved in compared to control

Dr. Krishna BH, the lead author said, "Twelve-week yoga therapy significantly improved the parasympathetic activity and decreased the sympathetic activity in heart failure patients."

Truly, yoga mindfulness induced relaxation of central nervous system in inhibited production of stress hormone in facilitated production of inflammatory makers through interaction between immune cells-particularly macrophages and lymphocytes, one of number of markers involved in heart failure disease progression.

Chronic psychological stress is found to have string negative influence in heart failure patients as the result of losing the ability to regulate the inflammatory response.

Also, yoga slow breathing and meditation induced relaxation the central nervous system in stimulated production of nitric oxide NO through expression of nitric oxide synthase (iNOS) in relaxed the vessel muscles and heart muscles in regulation dilation and reduced stress hormone in over production of prostaglandins E2 in activated muscle constriction, plus improving in heart rate, blood pressure and rate pressure product (RPP).

Furthermore, yoga selected postures was found not only to improve flexibility but also enhance the function lung in optimized oxygen demand of the heart through circulatory system controlled by homeostatic mechanisms without inducing work overload to the heart, thus increasing peak exercise capacity (peakVO2) in patients with heart failure.

These results suggested that yoga intervention exerted a significant effect in improved cardiovascular endurance in all aspects.

Moreover, yoga mindfulness reconnected and re-balanced the mind and body by bring back the presence while dealing with a profound and effective way that lead to actively engage in healthy diet and change of life style in participated improvement in functional capacity.
  
These finding evidences suggested that yoga, as a integrated exercise has a direct impact in enhance health and quality of life in patients with heart failure.

The result of above were supported by the randomized controlled trials, in the review of literature published on MEDLINE, Cochrane Central Register of Controlled Trials, Excerpta Medica database, LILACS, Physiotherapy Evidence Database, together with the Scientific Electronic Library Online, and Cumulative Index to Nursing and Allied Health up to December 2013.

According to the study, in compared to control, researchers indicated that
* Yoga group displayed a significant and positive impact on peak exercise capacity (peakVO2) and quality-of-life (HRQOL)
*Yoga participants also showed an improvement of Weighted mean differences (WMD) (some of the studies make a greater contribution to the average than others and global HRQOL standardized mean differences).
In clarification of the efficacy in treatment for CHF, Dr. Gomes-Neto M, the lead author said,"Yoga enhances peak VO2 and HRQOL in patients with CHF and could be considered for inclusion in cardiac rehabilitation programs".

And, the study of 40 patients (38 AA, 1 Asian, and 1 Caucasian) with systolic or diastolic HF randomized to the yoga group (YG, n = 21) or the control group (CG, n = 19) with all patients followed a home walk program, suggested that yoga group demonstrated a significant improvement of all tested aspects, such as for flexibility (P = 0.012), treadmill time (P = 0.002), VO2peak (P = 0.003), and the biomarkers (IL-6, P = 0.004; CRP, P = 0.016; and EC-SOD, P = 0.012) in compared to control

Taking altogether, Yoga therapy may offer additional benefits to the standard medical care to patients with HF by improving cardiovascular endurance, inflammatory markers, flexibility and quality of life.


For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effect of yoga therapy on heart rate, blood pressure and cardiac autonomic function in heart failure by Krishna BH1, Pal P2, G K P3, J B4, E J5, Y S6, M G S7, G S G8.(PubMed)
(2) Effects of Yoga in Patients with Chronic Heart Failure: A Meta-Analysis.[Article in English, Portuguese]by Gomes-Neto M1, Rodrigues-Jr ES1, Silva-Jr WM2, Carvalho VO2.(PubMed)
(3) Benefits of yoga for African American heart failure patients by Pullen PR1, Thompson WR, Benardot D, Brandon LJ, Mehta PK, Rifai L, Vadnais DS, Parrott JM, Khan BV.(PubMed)
(4) Role of Inflammation in Heart Failure by Shirazi LF1, Bissett J1, Romeo F1,2, Mehta JL3.(PubMed)

Friday, 23 February 2018

Herbal Therapy: Green Tea Significantly Improved Glucose Metabolism in Prediabetics

Kyle J. Norton 

Green tea may have a therapeutic and positive effect in improved glucose metabolism, some scientists suggested.

Green tea is a precious drink processed numbers of health benefit and known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

Glucose metabolism is an action of the body to convert glucose intake to energy to nourish the body tissues and organs through oxidized to carbon dioxide and water.

Long term abnormal glucose metabolism is considered as a leading cause of diabetes and diabetic complications.

Green tea extract, in the evaluation of the on carbohydrate metabolic key enzymes in control and streptozotocin high fat diet -induced diabetic rats in 30 days, demonstrated a significant activity in ameliorated the over expression of plasma glucose, glycosylated hemoglobin (HbA1c) and increase in the levels of insulin and hemoglobin.

Further analysis also found that the application exerted a profound effect in restore, in some extends, the function of altered activities of the key enzymes of carbohydrate metabolism, such as hexokinase, pyruvate kinase, lactate dehydrogenase in both diabetic and control groups.

In diabetic rats group, green tea extract strongly averted the abnormal expression of glycogen phosphorylase in liver to near normal levels.

Additionally, diabetic group after administration of green tea extract exhibited antihyperglycemic potential, obsevered through improved muscle and hepatic glycogen content.

The information findings showed green tea extract have a directed implication in attenuated abnormal glucose metabolism in compared to the effectiveness of conventional medicine metformin, a standard oral hypoglycemic drug.

Moreover, in the study to confirm the epidemiological study suggestion of improvement in glucose metabolism in diabetic mice and healthy humans upon green tea consumption, researchers found that
injection green tea in diabetic mice and streptozotocin-induced diabetic mice after 2-6 h expresses lower levels of glucose with no alternation of serum insulin level, at dose of 300 mg/kg in compared to normal control mice.

In protein differentiation, green tea extract administration decreased the serum protein level which has been associated to glucose production, minimized the increase of blood glucose levels through stmulating additional small amounts of insulin in the diabetes.  These results addressed another indication of green tea function in exerted direct influence in modulation of glucose metabolism in the tested subject.

Interestingly, in the investigation of green tea effect in glucose uptake inhibitory activity in Caco-2 cells, researchers indicated that green tea at temperature of 60 degree in Celsius significantly improved capacity of antioxidant in inhibition of glucose uptake through regulation of cell glucose metabolism.

Incredibly, temperature over 60 degree Celsius, green tea application did not increased or showed a up ward trend in the inhibitory potential, the Huazhong Agricultural University suggested.

Taken together, green tea with abundant bioactive phytochemicals may be considered as a function food in improved glucose metabolism in reduced risk of diabetes onset. People in high risk diabetes such as prediabetics may want to add 1 or 2 cups of green tea into their diet for preventive measure.



For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women 


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Modulatory effect of green tea extract on hepatic key enzymes of glucose metabolism in streptozotocin and high fat diet induced diabetic rats by Sundaram R1, Naresh R, Shanthi P, Sachdanandam P.(PubMed)
(2) Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans by Tsuneki H1, Ishizuka M, Terasawa M, Wu JB, Sasaoka T, Kimura I.(PubMed)
(3) Effect of steeping temperature on antioxidant and inhibitory activities of green tea extracts against α-amylase, α-glucosidase and intestinal glucose uptake by Liu S1, Ai Z2, Qu F3, Chen Y4, Ni D5.(PubMed)