Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Friday, 26 January 2018

Herbal Therapy: Green Tea and Its Bioactive Polyphenol in Reduced Risk and Treatment of All Forms of Acne

Kyle J. Norton

Green tea may have a therapeutic and positive effect in prevention and treatment of acne, some scientists suggested.

Green tea, is a precious drink with numbers of health benefit known to almost everyone in Asia and Western world.

Acne is a condition of skin diseases characterized by the occurrence of inflamed or infected sebaceous glands in the skin.

In the examined the effects of EGCG, the bioactive major polyphenol of green tea on human SEB-1 sebocytes with function in secreted sebum in patients with acne, researchers found that EGCG exerted a significant antioxidant activity in reduced sebum secretion by modulating the AMPK -SREBP-1 signaling pathway through AMPK expression in stimulated EGCG effect in regulated the interaction of phosphorylates sterol regulatory element binding proteins SREBP-1.

Application of green tea EGCG also demonstrated a strong effect in reduced sebum in induction of inflammation of sebaceous glands by suppressing the NF-κB in induced transcription of proinflammatory genes in cellular response to stress and pathogens and AP-1 pathway, a transcription factor with function in regulated gene expression of inflammation factors in response to a variety of stimuli, including bacterial and viral infections.

Furthermore, administration of EGCG also found to have a huge effect in targeting almost all the pathogenic features of acne through exhibited a significant cytotoxicity of SEB-1 sebocytes in induction of viability of P. acnes,

Dr. Yoon JY, the lead author at the Seoul National University Hospital, after taking into account of all findings said, " EGCG significantly improved acne in an 8-week randomized, split-face, clinical trial, and was well tolerated".

Amazingly, the randomized, double-blind, placebo-controlled clinical trial conducted from May 2012 through October 2013.of a total of 64 of 80 women, from 25 to 45 years of age with moderate-to-severe acne randomly assigned to receive either 1500 mg of decaffeinated GTE or placebo (cellulose) daily for 4 weeks indicated that there were statistically significant differences in inflammatory lesion counts found on the nose, periorally and on the chin between the two groups but no significant differences of total lesion counts.

Within group, green tea application displayed significant reductions in inflammatory lesions distributed on the forehead and cheek with no difference in total lesion counts.

Moreover, green tea group also resulted in significant reduction of total cholesterol levels in compared to cellulose group.

However, due to limitation of the small sample and short time period, researchers postulated that more research is required to determine whether a decaffeinated GTE standardized for EGCG content will provide clinical benefits in women with post-adolescent acne.

Additionally, in selected 59 studies with eight met the inclusion criteria to evaluate the effect of tea polyphenols in reduced sebum production in the skin and for treatment of acne vulgaris by reviewing the literature published on PubMed, researchers suggested that application of tea polyphenols topically may have a beneficial effect in reducing sebum secretion and in treatment of acne through inhibited lipid synthesis by the sebaceous glands.

Truly, according to the University of Miami, in the examine 12 patients with mild-to-moderate acne vulgaris received green tea application twice daily for a period of 6 weeks, topical injection of 2% green tea lotion was found to be effective in treatment with statistically significant in mean total lesion count (TLC) decreased from 24 measured at the baseline to 10 after 6 weeks treatment, a reduction of 58.33%.

The mean severity index (SI) from all patients also decreased from 2.05 before treatment to 1.25 after 6 weeks treatment, a decrease of 39.02%.

Dr. Elsaie ML, the lead scientists said, "Topical 2% green tea lotion is an effective, cost-effective treatment for mild-to-moderate acne vulgaris".

Taking altogether, green tea and its bioactive major polyphenol may be used safely in reduced risk, progression and treatment of all form of acne pending to a large sample size and multi centers clinical trial. Oral administration of green tea should be taken with exceptional care as some cases of acute liver toxicity were reported literaturally.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women

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Sources
(1) Green Tea and Other Tea Polyphenols: Effects on Sebum Production and Acne Vulgaris by Saric S1, Notay M2, Sivamani RK(PubMed)

(2) Does supplementation with green tea extract improve acne in post-adolescent women? A randomized, double-blind, and placebo-controlled clinical trial by Lu PH1, Hsu CH2.(PubMed)

(3) Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes by Yoon JY1, Kwon HH, Min SU, Thiboutot DM, Suh DH.(PubMed)
(4) The efficacy of topical 2% green tea lotion in mild-to-moderate acne vulgaris by Elsaie ML1, Abdelhamid MF, Elsaaiee LT, Emam HM.(PubMed)

Alternative Therapy: Yoga in Modulation of Immune Response

Kyle J. Norton

Yoga may be considered as a home base exercise in improved immune response against foreign substances invasion according to online public medical studies.

Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the study by Dr. Arora S and colleagues, yoga practice regularly may reduce risk of stress influenced in immune expression through deactivation of many connected mechanisms, including reduced alterations in the number of immune cells and cytokine dysregulation.

Yoga therapy has been found to reduce the psychological and physiological effects of stress in cancers and HIV infection.

In deed, yoga intervention improved the immune lymphocytes (T cells) in cell-cell interaction and the release of mediators such as antibodies (in the case of B cells), cytotoxic granules (cytotoxic T cells) or by signaling to other cells of the immune system in inhibited antigen.

Immune dysfunction caused by long term stress has been found to have strong implications in reduced immune response to foreign substances invasion, including vaccines, delayed wound healing and improper reaction to infectious diseases.

In further demonstration of yoga effect in increased immune response, the Lady Hardinge Medical College carried out a study included sixty first-year MBBS students randomly assigned to yoga group and control group (30 each), with yoga group underwent integrated yoga practices for 35 minutes daily in the presence of trained yoga teacher for 12 weeks and control group did not undergo any kind of yoga practice or stress management, after taking into account of other co founder, demonstrated that
* There was no significant difference observed in physiological parameters during the examination stress, in compared to a significantly increased stress in control
* Indicator of expressed assay also found higher stress in the control than those in yoga group
* Hormone status also showed the increased serum cortical and decreased serum IFN-γ in yoga group was less significant (P<0.01) than in the control group.

* Yoga displayed a lesser inflammatory status in compared to control

Dr. Gopal A, the led author said, "Yoga resists the autonomic changes and impairment of cellular immunity seen in examination stress".

Truly, Yoga participation in exertion of ameliorated stress on immune system was found to be mediated by a complex network of signallings involving various aspects including nervous, endocrine, and immune systems through expression and interaction of neurotransmitters, neuropeptides, hormones, and cytokines, according to Dr. Sarika Arora and Jayashree Bhattacharjee.

The endocrine-immune system network including adrenal and pituitary glands secreted hormone binding to receptors of white blood cell in response to expression of the release of cytokines in the acute phase and chronic inflammation and these hormones and cytokine concentration are alternated in patients with prolonged stress.

These results according to some yoga instructors were attributed to the effect of yoga relaxation and meditation in stimulated production of a steroid hormone called glucocorticoids (GCs) which has been found to enhance the immune systems and prevented immune abnormal activity.

Some researchers suggested that such change(hormones and cytokine concentration are alternated in patients with prolonged stress.) subsequently induced immune dysfunction, leading to abnormal sleep pattern and behavioral changes such as a reduction in activity, social interaction, sexual activity and psychological expression of increased responsiveness to pain, anorexia, and depressed mood.

Further to support the effects of yoga intervention in improved immune response, researchers at the joint study led by the Healthcare Global, conducted a study of 91 patients with metastatic breast cancer satisfied selection criteria, randomly assigned to receive "integrated yoga based stress reduction program" (n = 45) or standard "education and supportive therapy sessions" (n = 46) over a 3 month period, showed that
* Participants expressed a strong improvement of symptom distress, sleep parameters and quality of sleep and insomnia .
* Yoga lesson also decreased in morning waking cortisol in compared to standard group
* Yoga group displayed a significant improvement in NK cell percent

Taking altogether, the finding evidences suggested that yoga intervention may have a positive and profound effect in improved immune response when come under attacks by foreign substances invasion, including virus and bacteria.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Modulation of immune responses in stress by Yoga by Arora S, Bhattacharjee J.(PubMed)
(2) Effect of integrated yoga practices on immune responses in examination stress - A preliminary study by Gopal A1, Mondal S, Gandhi A, Arora S, Bhattacharjee J.(PubMed)
(3) Effect of Yoga on Sleep Quality and Neuroendocrine Immune Response in Metastatic Breast Cancer Patients by Rao RM1, Vadiraja HS2, Nagaratna R2, Gopinath KS3, Patil S4, Diwakar RB4, Shahsidhara HP4, Ajaikumar BS5, Nagendra HR6.(PubMed)
(4) Modulation of immune responses in stress by Yoga by Sarika Arora and Jayashree Bhattacharjee(PMC)

Thursday, 25 January 2018

Herbal Therapy: Herbal Anise In Attenuated Risk, Progression and Treatment of Neuro degenerative Disease

Kyle J. Norton

Anise may have a potential and substantial effect in reduced risk and progression and treatment of neuro-degenerative disease, some scientists suggested.

Anise is a flowering plant ofthe species of Pimpinella anisum, genus Pimpinella, belongings to the family Apiaceae native to to Egypt and the Mediterranean region, used in traditional herbal medicine as fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic, ....

Chemical comstituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.

Neurodegenerative disease is the progressive condition characterized by loss of structure or function of neurons, including death of neurons leading to amyotrophic lateral sclerosis, Parkinson's, Alzheimer's, and Huntington's disease

According to statistic as of today 5 million Americans suffer from Alzheimer'sdisease; 1 million from Parkinson's; 400,000 from multiple sclerosis (MS); 30,000 from amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), and 30,000 from Huntington's disease. By 2030, the disease is estimate to increase substantial as many as 1 in 5 American elder over the age of 65

According to the vivo and in vitro experimental models, application of essential oil isolated from anise expressed a significantly neuro protective effect in seizure attacks induced by pentylenetetrazol (PTZ) injection and neuronal hypoxia induced by oxygen withdrawal as well as on production of dark neurons and induction of long-term potentiation (LTP).

Further examine, researchers found that injection of Anise oil significantly prolonged the period between seizure attacks by inhibited the production of dark neurons activated by depolarization, glutamate release caused by toxicity of pentylenetetrazol (PTZ) to induce neuron collapsed in different regions of the brain in epileptic rats and reduced the amplitude and duration of epileptiform burst discharges due to neuron abnormal excitability induced by injection of intraperitoneal PTZ

Moreover, application of Anise essential oil also significantly enhanced the duration of the appearance of anoxic terminal negativity in the CA1 region of hippocampal slices in initiated neuro protective effect through direct stabilization of the cell membrane after acute onset of hypoxia and ischemia caused by oxygen withdrawal and inhibited induction of LTP.

Dr. Karimzadeh F, the lead author, after taking into account of other con founders said, "the anticonvulsant and neuroprotective effects of anise oil, likely via inhibition of synaptic plasticity".

Additionally, the investigate the Pimpinella anisum (Anise) on the physiological and neurological parameter on normal and diabetic rats induced by Streptozetocin (STZ), by assigning rats randomly to eight groups: 1P stP control group and received citrate buffer, 2P ndP diabetic group treated with STZ (50mg/kg. b. wt), 3P rdP BPA group treated with BPA (30mg/kgbwt), 4P thP Anise group treated with anise oil. (3g/kgb. wt),5P thP STZ + BPA group combination between STZ and BPA with the same dose, 6P thP group treated with (STZ+Anise), 7P thP group treated with (STZ + Anise + BPA) and 8P thP group received Anise and BPA indicated that rat group treated with Anise (STZ + Anise) and diabetic rats treated with (Anise + BPA) exerted a significant decrease the levels of Norepinephrine(NE) in stimulated stress, mood, restlessness and anxiety disorders caused by oxidative stress.

Interestingly, rat group treated with Anise alone or combined with other substances also reduced the levels of dopamine (DA) and the 5-HT in induction of neuro toxicity in comparison with vehicle and diabetic (STZ) group.

These result suggested that treatment of Anise decreases neurotoxic effect induced by (BPA), particularly, in application of BPA increased substantial toxicity in diabetes in compared to control.

Further to support the efficacy of essential oil of Pimpinella anisum in protection against neuro degenerative disease, researchers at the Saida University conducted an experiment to test the anxiolytic and antidepressant effects of the essential oil against chronic lead acetate (0.2%) intoxication during the gestation and lactation period, in Wistar rat pups, the results suggested that injection of toxic chemical induced impairments of brain weight and increased psychological parameters of the level of anxiety, depression and locomotor hyperactivity in compared to control rats were inhibited by administration of Anise essential oil without causing effect of brain weight

Taken together, Anise essential oil may be considered as an adjunct therapy to reduced risk and used combination with conventional standard medicine in attenuated progression and treatment of neuro degenerative disease.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN

Sources
(1) Anticonvulsant and neuroprotective effects of Pimpinella anisum in rat brain by Karimzadeh F1, Hosseini M, Mangeng D, Alavi H, Hassanzadeh GR, Bayat M, Jafarian M, Kazemi H, Gorji A.(PubMed)
(2) NEUROPROTECTIVE EFFECTS OF PIMPINELLA ANISUM ON NEUROTOXICITY Full Proceeding Paper INDUCED BY BISPHINOL A ON NORMAL AND DIABEITC RATS by FAWKYEIA A. EL-HODAIRY Physiology Department, NODCAR, Giza, Egyp
(3) Neuro beneficial effects of Pimpinella anisum against lead exposure by Khaled Kahloula, Miloud Slimani, Djallel Eddine Houari Adli, Sahra Rachdi, Dallel Boumediene Department of Biology, Biochemistry Laboratory, Saida University, Saida 20000, Algeria

Alternative Therapy: Yoga Intervention in Reduced Risk of Preterm Labor

Researchers may have found a home base exercise tailored to the need of women in prevented risk of preterm labor, according to the online public medical library studies.

Yoga, the ancient practice for harmonized external and internal body wellbeing, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

Preterm labor is the preterm birth of any infant before 37 weeks of pregnancy.

In the review of literature to evaluate the peripartum outcomes of yoga during pregnancy, including the postpartum period and lactation by searching PubMed database online, scientists found that
* The nonrandomized trials indicated yoga intervention showed a significant reduction in rates of preterm labor
* Randomized control trials (RCTs) indicated that yoga therapy during pregnancy can significantly lower pain and discomfort.

In deed, yoga mindfulness practice relaxed and connected the mind and body by bringing back the presence of natural state of motherhood of protection of the babe with love and care in induction of healthy eating and letting go or dealing the unfavorable events which caused stress in the positive ways, thus reducing pain and discomfort during pregnancy.

The reduction of stress, the natural state of motherhood and healthy eating improved the digestive function in in absorption of nutrients and oxygen and enhanced the circulatory system in moving more blood to the abdomen to feed the health and normal growth of the baby.

Further analysis of the stress reduction also discovered that yoga intervention ameliorated risk of intrauterine and uterus infection which have been considered as some physical causes of preterm birth, by significantly increased immune function in protection against bacterial and viral invasion passing through the vagina and the cervix, the amniotic cavity and the fetus.

Moreover, yoga induced immune activities also protected the baby during the acute phase of infection by regulating production of anti inflammatory mytokines and pro inflammatory cytokines in ameliorated symptoms of inflammation.

Additionally, in the relaxation of the central nervous system through reducing stress, yoga also promoted hormone balancing in decrease over production of certain hormones such as prostaglandins in stimulated production of nitric oxide in initiated uterus muscle contraction in contributed embryonic and fetal expulsion.

Interestingly, in the examine the implication of oxidative stress in risk of preterm birth induced by damage to intrauterine tissues and fetal membranes of the placenta. some researchers suggested that yoga intervention reduced stress also have a profound effect in inhibited nervous system sympathetically in production of hormone catecholamines to induce cytotoxic free radicals formation through induction of over production for antioxidants from healthy food sources and natural antiooxidant from the body.

Truly, antioxidants levels of total glutathione (GSH) contents, GSH-peroxidase, and GSH-s-transferase were found higher and oxidative stress marker Malondialdehyde (MDA) was significant lower in women participating yoga lesson in compared non yoga women.

Finally, in the support of the above differentiation, a study of 335 women attending the antenatal clinic at Gunasheela Surgical and Maternity Hospital in Bangalore, India, enrolled between 18 and 20 weeks of pregnancy in a prospective, matched, observational study; 169 women in the yoga group and 166 women in the control group also indicated that

*Yoga group expressed a higher number of babies with birth weight > or = 2500 grams in compared to control group.
*The relative risk ratio of preterm labor in yoga intervention group also substantially lower in compared to control.
*Yoga therapy is safe with no significantly adverse effect

The study also confirmed that yoga practice not only is safe but also reduces risk of preterm labor and improved birth weight, pregnant discomforts and reduced risk of complications.

Taking altogether, there is no doubt that yoga intervention during pregnancy may have a profound effect in reduced risk of preterm labor, particularly, in high risk women with unfavorable family history.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Yoga during pregnancy: a review by Babbar S1, Parks-Savage AC, Chauhan SP.(PubMed)
(2) Oxidative stress damage as a detrimental factor in preterm birth pathology by Menon R1.(PubMed)
(3) Efficacy of yoga on pregnancy outcome by Narendran S1, Nagarathna R, Narendran V, Gunasheela S, Nagendra HR.(PubMed)

Wednesday, 24 January 2018

Herbal Therapy: Green Tea In Reduced Risk of Subarachnoid Hemorrhage (SAH)

Kyle J. Norton

Green tea may have a therapeutic and positive effect in reduced risk hemorrhage, some scientists suggested.
Green tea, is a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.

Hemorrhage is a condition of vessel rupture, leading to bleeding within the brain tissue.

In the investigation of the effects of green tea polyphenols intake and the risk of subarachnoid hemorrhage (SAH) study, researchers at the Henan Institute of Science and Technology found that

administration of green tea reduced early onset of SAH through prevented alteration of mitochondrial membrane potential to basal level.

Further analysis, also suggested that green tea pre-treatment also decreased production of Adenosine triphosphate(APT) content, a vasoactive compound found in high concentrations after subarachnoid hemorrhage and the cytochrome c level to induced cell death in the brain cortex after 12 hours in the tested models.

These result suggested that green tea administration not only exerted a significant neuro protective effect against polarization of mitochondrial membrane potential and prevented production of certain proteins and enzymes in induction of brain damage.

Indeed, over the course of study of a total of 180 mice, 8 (4.4%) died during the experiment, 5 (8.3%) in the SAH group, 3 (5.0%) in the tea polyphenols pretreated model, and 0 in the control group.

And the differentiation of the neurological scores observed for mice with SAH was significantly lower than that of the sham group from 6 h to 72 h after SAH occurrence..

Additionally, pretreatment with tea polyphenols expressed a significant decrease activity lactic acid dehydrogenase (LDH) levels in the blood stream, an indication of brain tissue injured and damage in compared to the untreated SAH group.

Dr. Mo H, the lead scientist after taking into account of others con-founders, said, "After pretreatment with tea polyphenols, the neurological outcome was also improved(through various implications)".

Interestingly, in a designed to determine the effects of consumption of green tea in reduced risk for subarachnoid hemorrhage (SAH) in a case-control study consisting incident SAH cases of n=201 matched by age (+/-2 years) and gender to hospital (n=201) and community controls (n=201) from April 1992 to March 1997, researchers at the Aichi Prefectural College of Nursing and Health suggested that habital green tea consumption is associated inversely in risk of subarachnoid hemorrhage (SAH).

People who drank one or more cup of green tea per day scored a significant lower risk of 60.3% in compared non tea drinking group of 70.9%.

More specifically, testing subjects who consumed <1, and >or=1 time per day showed a strong ameliorated risk with adjusted over all risk ratio of 0.74 and 0.56 respectively, in compared non daily green tea drinkers.

Okamoto K suggested that risk of subarachnoid hemorrhage (SAH) is significant reduced linearly depending to numbers of cup of green intake per day.

Taken together, green tea as powerful antioxidant activity may be considered as functional food in reduced risk of subarachnoid hemorrhage (SAH) and used combination with standard medicine for post treatment of the incidence.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women

Sources
(1) Neuroprotective effect of tea polyphenols on oxyhemoglobin induced subarachnoid hemorrhage in mice by Mo H1, Chen Y, Huang L, Zhang H, Li J, Zhou W.(PubMed)
(2) Habitual green tea consumption and risk of an aneurysmal rupture subarachnoid hemorrhage: a case-control study in Nagoya, Japan by Okamoto K1.(PubMed)
(3) Dietary antioxidant intake and risk of an aneurysmal rupture subarachnoid hemorrhage in Japan by Okamoto K1, Horisawa R.(PubMed)

Alternative Therapy: Yoga, the Best Form of Exercise in Reduced Risk of Oxidative Stress-Related Diseases

Kyle J. Norton (Scholar, All right reserved)

Scientists may have found a safe and low cost home base exercise in increased antioxidants in fighting against free radical and inflammations in infectious expression, according to studies published online public medical library.

Yoga, the ancient technique for harmonized external and internal body wellbeing, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study on healthy volunteers recruited from among university students, divided into two groups: a control (no yoga intervention, n=13) group and a yoga (n=12) group with practice with an instructor for 90 minutes once a week spread over 12 weeks, with recommendations to practice daily at home for 40 minutes with the help of a DVD, researchers indicated that free radical expression of serum levels of nitric oxide, F2-isoprostane, and lipid peroxide were significantly decreased in yoga group due to yoga in stimulated production of antioxidants in interception of free radicals unstable configuration in release of electrons before exerting chain reaction in compared to control.

In deed, yoga breathing and meditation enhanced the the balance of body and mind, caused by the stress, thus improving the blood circulation to nourish the cells in the body with nutrients and oxygen and keep the free radicals in check which are present in our body through daily activities such as breathing, exposure to the environment, food intake,....

The environment superoxide anion, hydrogen peroxide and extremely reactive hydroxyl radical in induction of oxygen toxicity are also inhibited by antioxidant over expression in yoga group.

Yoga intervention also reduced stress in exhibited nervous system sympathetically in production of hormone catecholamines to induce cytotoxic free radicals formation in initiated disease progression.

Furthermore, yoga exercise increased digestive system in generated antioxidants such as serum total glutathione (GSH) contents, GSH-peroxidase, and GSH-s-transferase through food intake to balance the over expression of ROS activities but also reduced stress implication in production of Malondialdehyde (MDA)which is considered a marker of oxidative stress in compared to control, observed by the initial blood samples obtained from both the group before and after yoga training.

Additionally, researchers also found that beside improved antioxidant explicitly, yoga group also significantly increased immune function in protection of our body against damage to the body during the acute phase of infection by regulated production of anti inflammatory mytokines and pro inflammatory cytokines in ameliorated symptoms of inflammation.

More importantly, unlike the other types of exercise, yoga group also demonstrated a significant lower levels of nitric oxide, a free radical with duo activity but in excess, it can cause certain damage to the body tissue.

Dr. Lim SA , the led author said, "Regular yoga practice remarkably attenuated oxidative stress and improved antioxidant levels of the body".

In a study of healthy male volunteers from the Indian Navy, divided into two groups--a yoga (n = 30) group and a control (n = 21) group with yoga group trained in yoga for 6 months and the schedule consisted of prayers, asana, pranayama, and meditation and the control group practiced routine physical training exercise for 6 months, researchers also found the similar conclusion as mentioned in the above study.
Yoga participated group demonstrated a reduced glutathione level at the beginning but increased significantly at the end of training in compared to control group.

Interestingly, in compared to the levels of antioxidant in the both groups researchers surprisingly found that total antioxidant status were increased strongly in the yoga group but decreased significantly in the control group.

After taking into account of other co founders, researchers recommended. "Regular practice of yoga can maintain or improve antioxidant level of the body".

Due to yoga effect in promoted antioxidant and reduced oxidative stress through improved immune activities, some researchers suggested yoga may be used as an home base excise to promote healthy lifestyles (balanced diet and moderate intensity exercise) in vulnerable populations, such as menopausal women, in prevention of aging induced oxidative stress-related diseases, according to the study of an urban community in Bangkok (Thailand) between May and August 2007 conducted by the Université de Nice Sophia-Antipolis, in premenopausal and postmenopausal women.

Taking altogether, the findings showed that yoga indeed can be considered as an integrated form of exercise to improve antioxidant expression in reduced chronic illness caused by oxidative stress.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Regular Yoga Practice Improves Antioxidant Status, Immune Function, and Stress Hormone Releases in Young Healthy People: A Randomized, Double-Blind, Controlled Pilot Study.
Lim SA1, Cheong KJ1.(PubMed)

(2) Improvement of glutathione and total antioxidant status with yoga by Sinha S1, Singh SN, Monga YP, Ray US.(PubMed)

(3) Dietary intakes and antioxidant status in mind-body exercising pre- and postmenopausal women by Palasuwan A1, Margaritis I, Soogarun S, Rousseau AS.(PubMed)
(4) Effect of yoga on Free radical and Antioxidant status in Healthy Adults Mahalakshmamma Vandavasi 1 , Puli Sreehari 2 , Chintala Durga Sukumar(ORIGINAL ARTICLE)

Tuesday, 23 January 2018

Herbal Therapy: Herbal Anise In Expression of Antidepressant-like Activity

Kyle J. Norton

Anise may have a potential and substantial effect in reduced risk and treatment of dpression, some scientists suggested.

Anise is a flowering plant ofthe species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to to Egypt and the Mediterranean region, used in traditional herbal medicine as fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic, ....

Chemical comstituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.

Depression is a condition of mood disorder. affecting the patients feel, think, and handle daily activities.

According to statistic of The National Institute of Mental Health, approximately, 16 million adults had at least one major depressive episode in 2012 in the United States, a 6.9 percent of the population.

In the evaluation of the herbal Anise aqueous and ethanol extracts antidepressant-like effect in mice with several different doses of 50, 100 and 200 mg/kg in compared to the standard medicine Fluoxetine at dose of 30mg/kg and and imipramine at dose of 20mg/kg, researchers at the joint study lead by the Azad University showed that except the dose at 50mg/kg of aqueous extract, application of other doses demonstrated a linearly significant improvement of mobility times.

Further analysis also found that all doses from Anise extract increased the swimming time dose-dependently, without any significant change in climbing time in tested mice similar to those of Fluoxetine and in compared to aqueous extract.

Moreover, Fluoxetine and imipramine expressed a strong decreased immobility time in both tests in contrast to imipramine increased climbing time without any significant change in swimming time.

The result suggested that both extracts in dose higher than 50mg/kg display antidepressant-like activity similar to that of fluoxetine through improved mobility of depressed mice as inactivity is considered as one of major symptoms in patients with depression.

As the depression progressed, patients demonstrated a behavior in making efforts to escape from society, eventually will exhibit immobility with reflection of psychological despair.

Dr. Shahamat Z the lead author said, " P. anisum possesses an antidepressant-like activity similar to that of fluoxetine, which has a potential clinical value for application in the management of depression".

Additionally, in the testing essential (volatile) oil and essential oil of Piper laetispicum antidepressant activity in compared to Fluoxetine as standard antidepressant drug and other natural remedies including Leaves-Bay, Curry, Coriander and Mint; Fruits-Star anise, Pepper, Cardamom, Caraway and Fennel; Seeds of Fenugreek, Mustard, Nutmeg and Black Cumin; and Underground stem-Onion, Garlic, Ginger and Turmeric; Miscellaneous-Clove, Cinnamon, Capsicum, Tamarind and Asafoetida, reserachers found that all participated essential oil, specially anise produced a significant reduction in immobility along with an increase in climbing behavior similar to those of fluoxetine.

The application of essential oil caused a dose -dependent reduction( probably in dose less than 50 mg/kg) in immobility which is contracted to the above study and an increase in climbing at all studied doses in compared to control group.

However, the test may not take into effect in real life patients who need to be treated for at least several weeks before they experience any relief from expression of symptoms.

Further more, in the examine of the efficacy of anise oil, in removing the symptoms of mild to moderate depression in patients with irritable bowel syndrome of a total of 120 randomly assigned into 3 equal groups received anise oil, Colpermin, and placebo, at the end of the study, scientists showed that application of anise group exerted a continuously improvement of the syndrome in compared to the other 2 groups with some unknown mechanisms.

Some researchers postulated that essential oil smell may have a profound effect to the brain in triggering emotional reaction in stimulating the limbic system in regulated autonomic and endocrine function, particularly, in response to emotional stimuli in expression of motivation and reinforcing behaviors.

Additionally, the application of essential oil scent also have a direct influence in calming the central nervous system in ameliorated over production of certain hormones in reacted to the unfavorably emotional behaviors.

Taken together, Anise essential oil may be used as a secondary therapy to standard medicine in treatment of depression.

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Sources
(1) Evaluation of antidepressant-like effects of aqueous and ethanolic extracts of Pimpinella anisum fruit in mice by Shahamat Z1, Abbasi-Maleki S2, Mohammadi Motamed S3.(PubMed)
(2) Effectiveness of Anise Oil for Treatment of Mild to Moderate Depression in Patients With Irritable Bowel Syndrome. A Randomized Active and Placebo-Controlled Clinical Trial by Maryam Mosaffa-Jahromi, PharmD, PhD, Ali-Mohammad Tamaddon, PharmD, PhD, Suleiman Afsharypuor, PharmD, PhD, Alireza Salehi, MD, MPH, PhD, Seyed Hassan Seradj, PharmD, PhD, Mehdi Pasalar MD, MPH, PhD, Peyman Jafari, PhD, Kamran Bagheri Lankarani, MD (Journal of Evidence-Based Integrative Medicine)
(3) Essential oil isolation from culinary drugs and screening for antidepressant potential Mohib Abdul Jalil Khan , Imtiyaz Ansari, Amjad Ali Mohammad Iqbal Oriental College of Pharmacy, Navi Mumbai, Maharashtra- 400705, India.(INTERNATIONAL JOURNAL OF ADVANCES INPHARMACY MEDICINE AND BIOALLIED SCIENCES)
(4) The Forced Swim Test as a Model of Depressive-like Behavior by Roni Yankelevitch-Yahav, 1 , 2 Motty Franko, 2 Avrham Huly, 2 and Ravid Doron(PMC)

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