Tuesday, 21 November 2017

Herbal Therapy: Green tea, in Reduced Risk and Treatment of Alzheimer's disease

Kyle J. Norton

Green tea may an integrated form of treatment for patient with Alzheimer's disease through many mechanisms, a recent study proposed.

Green tea, considered as a functional food, linking numbers of health benefit has been reported by several renowned research and studies. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But a slice of ginger in the drink will neutralize the yin over expression in green tea.

Alzheimer's disease is a neuro-degenerative condition of loss or decrease of cognitive and memory functions due to aging.

According to the Maternal and Infant Health, ASL NA 3 SUD, epigallocatechin and gallic acid, (-)-Epigallocatechin-3-Gallate (EGCG), found in green tea exerted a strong anti-inflammatory and anti oxidative properties in protection against neuronal damage and brain edema.

The study also stated that green tea may also contribute to reduced risk and treatment of AD by ameliorated chronic viral infection, one of the cause in responsible for AD's neuropathology.

Dr. Mandel SA. the lead author and expert in green tea study said, "tea drinking may decrease the incidence of dementia, AD, and PD. In particular, its main catechin polyphenol constituent (-)-epigallocatechin-3-gallate (EGCG) has been shown to exert neuroprotective/neurorescue activities in a wide array of cellular and animal models of neurological disorders".

Other researchers suggested that the efficacy of  epigallocatechin and gallic acid, (-)-Epigallocatechin-3-Gallate (EGCG) in reduced risk of AD may be attributed to
1. The antioxidant activity in ameliorate production of ROS in induced risk of oxidative stress which has been found to associate to production of lipid peroxidation, leading to abnormal deposition of amyloid β (Aβ) peptide
2. Free radical over expression in aging people also vulnerable to imbalance of antioxidant and ROS
may have a negatively direct interaction with proteins, nucleic acids, and other molecules and may also alter their structures and functions in inducing risk AD.

Indeed, as a single ingredient isolated from green tea, epigallocatechin and gallic acid, (-)-Epigallocatechin-3-Gallate (EGCG) have been found to cause toxicity in some cases in medical literature. Therefore taking the ingredient in long term and overdoses may have a implication of liver damage.

In a animal study to evaluate the efficacy of Caffeic acid in AD, mice rats randomly divided into three groups: i) control group, ii) AD model group and iii) caffeic acid group, mice fed with the phytochemical expressed a significant in increased learning deficit and cognitive function demonstrated by the Morris water maze task in compared control.

Additionally, fed mice also displayed of attenuated oxidative stress, inflammation, nuclear factor‑κB‑p65 protein expression involved inflammatory cytokins production and suppressed caspase‑3 activity induced cell death and other mechanisms in the rats with AD.

Interestingly, inflammatory process has shown to have an negative role in increased risk of AD, by causing neuroinflammation, including brain cells such as microglia and astrocytes and subsequently in promoted dysfunction and neuronal death. Therefore by suppressing production of inflammatory cytokins, caffeic acid expressed a significant reduction of AD risk.

The efficacy in contribution of cognitive improvement following caffeic acid application may be due to its antioxidant activity and restoration of cholinergic functions, as deficiency of cholinergic function has shown to effect cognition, behavior and activities of daily living

Taking altogether, there is no doubt that green process a neuro protective against the risk and progression of patients with Alzheimer's disease (AD) attributed to some of the major chemical constituents. But intake of single ingredient isolated from green tea should be taken with care.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) The efficacy of Epigallocatechin-3-gallate (green tea) in the treatment of Alzheimer's disease: an overview of pre-clinical studies and translational perspectives in clinical practice by Cascella M#1, Bimonte S#1, Muzio MR2, Schiavone V3, Cuomo A1.(PubMed)
(2) Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases by Mandel SA1, Amit T, Weinreb O, Reznichenko L, Youdim MB.(PubMed)
(3) Effects of caffeic acid on learning deficits in a model of Alzheimer's disease by Wang Y1, Wang Y2, Li J1, Hua L3, Han B1, Zhang Y1, Yang X3, Zeng Z3, Bai H3, Yin H1, Lou J3.(PubMed)
(4) Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats by Deshmukh R1, Kaundal M2, Bansal V2, Samardeep2(PubMed).

Monday, 20 November 2017

Food Therapy: Beet, The Best in Prevention and Treatment of Bladder Cancer

By Kyle J. Norton

Intake of function food beet root regularly not only lowers the early occurrence but also provides a natural treatment of  bladder cancer without inducing adverse effects.

Bladder cancer is a medical condition characterized by irregular cell growth and multiplied disorderly and uncontrollably in bladder tissues.

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to University of Urbino 'Carlo Bo', betaxanthins and betacyanins, isolated from beet root exerted a significant anti cancer effects in testing bladder cancer cell lines, through expression of antioxidant and pro apoptotic activities.

The anti cancer property of beet root also displayed a strong anti angiogenesis by blocking the cancer cell in established new blood vessel signalling.

When used combination with Vitexin-2-O-xyloside, an apigenin flavone glucoside, betaxanthins and betacyanins also exerted a strong antiproliferative activity in bladder cancer cell lines, intrinsically and extrinsically in expression of apoptosis.

The study also indicated that these combination when used conjunction in  the conventional chemotherapy not only enhanced the effectiveness of treatment in bladder cancer but also overcome the adverse effect of  toxicity and multidrug resistance of cancer cells.

Furthermore, in other study conducted by the same university, Betacyanins (BC) purified from beetroot (Beta vulgaris var. rubra L.) tested,alone or in combination with vitexin-2-O-xyloside (XVX) also isolated from the same vegetable enhanced the ability to reduce the proliferation rate in T24 bladder cancer cells, synergistically.by inhibition of protein of gene in promoted cell survival and enhanced cancer apoptosis.

Taking together, a diet enriched with these bioactive molecules of beet root could be used as function food in prevention and treatment of human bladder cancer.



Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)
(2) Betacyanins enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells by Scarpa ES1, Emanuelli M2, Frati A1, Pozzi V2, Antonini E1, Diamantini G1, Di Ruscio G3, Sartini D3, Armeni T3, Palma F1, Ninfali P1.(PubMed)
(3) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)

Alternative Therapy: Yoga In Regulation of Gene Expression of Related Diseases

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Yoga intervention may have a potential effect in regulated gene expression in some related diseases, researchers at the University of Oslo suggested.

Mutated gene expression included many factors, most common factors are
1. Gene mutation inherited from gene defect parents
2. Gene expression may be altered in the process of regulatory sequences and the transcription factors, cofactors, chromatin regulators and noncoding RNAs
3. Gene mutation is a natural process to protect existence of human beings. Unfortunately, the process in some cases may produce certain subgroups who are vulnerable and susceptible to some diseases.

Biologically, unnatural causes of gene expression due to prolonged exposure to certain harmful agents such as environment toxins, long term used of single or multi ingredients medication,... may also induce genetic change to the negative ways.

Diseases caused by mutated gene expression, include cancer, autoimmunity, neurological disorders, diabetes...

Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to investigate whether the effects on the mind-body system in increased wellness and supported the healing process from diseases, researchers found that yoga intervention not only improved psychological and physiological functioning but also may have regulated effect in gene expression profiling in circulating immune cells, particularly in the molecular level.

Indeed, yoga can improve immunity through a sequence of post in strengthening the body and relaxing the mind. Some believed that by strengthening the body and relaxing the mind, yoga acted as regulators of gene expression in innate and adaptive cell of immune system, through noncoding RNAs, thus reducing risk of inflammatory and auto immune diseases.

In further exploration of the yoga effect in gene expression in the molecular level, researcher at the joint study led by the Coventry University, postulated that mind-body interventions (MBIs) showed a significantly reverse expression of genes involved in inflammatory reactions induced by stress.

Yoga, a mind-body practice of physical poses, controlled breathing, and meditation or relaxation has been best known to reduce implication of stress in increased production of inflammatory cytokins in gene expression, including interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF alpha), thus reducing risk of inflammatory diseases.

And after examined the changes in gene expression that occur after MBIs and to explore how these molecular changes are related to health, through searching the data base of published literature from PubMed throughout September 2016, researcher indicated that over all studies selected indicated an association of gene changes in yoga intervention was a result downregulation of nuclear factor kappa B pathway.

Furthermore, MBI practices may lead to a reduced risk of inflammation-related diseases, through the reduced effects of chronic stress on gene expression.

Most interestingly, in the assessed possible rapid changes in global gene expression profiles in the peripheral blood mononuclear cells (PBMCs) in healthy people practiced either a comprehensive yoga program or a control regimen, researchers found that SK&P program has a more rapid and significantly greater effect on gene expression in PBMCs compared with the control regimen.

Peripheral blood mononuclear cell (PBMC) include lymphocytes (T cells, B cells, NK cells) ,monocytes and granulocytes which play an important role in improved immune system cellular function in fighting against infection and inflammation, enhanced tissue regeneration, restored function due to injure, .....

Truly, the impact of yoga in protection of gene expression of immune system may involve a complexity of simple gene regulatory networks (GRNs), including the gene expression in PBMCs and inflammatory cytokins

Taking altogether, Yoga intervention and related practices may have a profound effect in gene expression alterations through a complex networks of simple gene regulation in the immune system.


Sources
(1) Regulation of gene expression by yoga, meditation and related practices: a review of recent studies by Saatcioglu F1(PubMed)
(2) Rapid gene expression changes in peripheral blood lymphocytes upon practice of a comprehensive yoga program by Qu S1, Olafsrud SM, Meza-Zepeda LA, Saatcioglu F.(PubMed)
(3) What Is the Molecular Signature of Mind-Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices by Buric I1,2, Farias M1, Jong J1, Mee C3, Brazil IA1,2,4,5.(PubMed)

Sunday, 19 November 2017

Herbal Therapy: Green Tea, The Liver Protective Functional Food

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Please note that the article does not embrace the use of single and multi ingredients extracted from green tea, particularly in the overdose state.

The use of plants for healing purposes has been predated long before the existence of modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Green tea may have a  potentially hepoprotective effect in prevention and treatment of liver disease, renowned institutes postulated.

Liver disease is a reduced function in toxin elimination of liver as a result of damage or injure, causing by medication, viral infection,....

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

According to the joint study lead by theZhujiang Hospital of Southern Medical University Guangzhou, in the review of the data base of PubMed, CNKI, Wanfang and Weipu databases, regular green tea drinking is associated to a significant reduction in the risk of liver disease, including hepatocellular carcinoma, liver steatosis, hepatitis, liver cirrhosis and chronic liver disease.

 Also, Green tea demonstrated a reduced risk of liver disease regardless of the race and geography of the patients resided such as Asian, American and European subgroups.

Unfortunately, in a mouse model, different doses of GT fractions and EGCG and a single dose of lipopolysaccharide (LPS) combined with EGCG, administered for 5 days to mice suggested that mice fed with combining a single high dose of EGCG with a single dose of LPS showed to induce liver injury.

Repeat injection of EGCG in the group also found to associate to mild liver injure, probably was attributed to the adverse effect of lipopolysaccharide (LPS), the study insisted.

Epigallocatechin Gallate (EGCG) is one of the major and powerful antioxidant of green tea found to  be most effective cancer chemopreventive polyphenol in many studies posted on medical literature. However, the single ingredients extract has also been found to induce hepotoxocity and acute liver dysfunction in many occasions due to overdoses and long term usages.

Additionally, according to the Baylor College of Medicine and  Dalhousie University, Halifax reported, "(There is) a case of acute impending liver failure in an adolescent male using a weight-loss product containing green tea extract" and "acute liver toxicity observed in individuals consuming supplements containing green tea extract".

Taking altogether, the conflict result of green tea in liver disease may be result of study design, group selection, sample size, doses intake,........People with liver disease should talk to a specialist of herbal products before consuming.



Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) The effect of green tea intake on risk of liver disease: a meta analysis by Yin X1, Yang J2, Li T3, Song L4, Han T5, Yang M1, Liao H1, He J1, Zhong X1.(PubMed)
(2) Effect of green tea and its polyphenols on mouse liver by Saleh IG1, Ali Z, Abe N, Wilson FD, Hamada FM, Abd-Ellah MF, Walker LA, Khan IA, Ashfaq MK.(PubMed)
(3) Green tea extract: a potential cause of acute liver failure by Patel SS1, Beer S, Kearney DL, Phillips G, Carter BA.(PubMed)
(4) Acute liver failure induced by green tea extracts: case report and review of the literature by Molinari M1, Watt KD, Kruszyna T, Nelson R, Walsh M, Huang WY, Nashan B, Peltekian K.(PubMed)
(5) Effect of epigallocatechin gallate on uncoupling protein 2 in acute liver injury by Mohammad H Jamal,1,* Hamad Ali,2 Ali Dashti,2 Jasim Al-Abbad,1 Husain Dashti,1 Chako Mathew,2 Waleed Al-Ali,3 Sami Asfar1(PubMed)

Food Therapy: Coffee, The Anti Edema Therapeutic Beverage

By Kyle J. Norton


Good news for coffee drinkers, coffee may have a potential effect in reduced risk and treatment of edema, a recent study suggested.

Edema is a condition characterized by excess fluid retained in body's tissues, inducing swelling.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the joint study lead by the Kyung Hee University, chlorogenic acid (CGA) isolated from coffee exerted protective effects of transient middle cerebral artery occlusion (tMCAo) rat model in ameliorated brain infarct volume and brain water content.

Chlorogenic acid (CGA) found abundantly in roasted coffee through expression of ester of caffeic acidand (−)-quinic acid, is an powerful antioxidant with profound effect in induced weight loss and edema.

Middle cerebral artery is a carotid artery supplied blood to the brain region involved the primary motor and sensory areas of the face, throat, hand and arm, and in the dominant hemisphere, the areas for speech.

The protective effect in reduced on ischemia-induced neuronal damage and brain edema.is attributed to dihydrocaffeic acid (DHCA), formed in metabolism of CGA in inhibited enzymes involved in the degradation of the extracellular matrix, namely MMP2 and MMP-9. in providing structural and biochemical support to the surrounding cells.

Dihydrocaffeic acid (DHCA) is a metabolite of caffeic acid with potent antioxidant properties.

Matrix metalloproteinase-2  and 9, (MMP-2 - 9) are enzymes with function in activated extracellular matrix (ECM), a collection of extracellular molecules secreted by cells to support the structure of cell. Over expression of MMP-2 and MMP-9 are found to associate to increased risk of disease progression, including arthritis and cancers.

In a rat model of transient middle cerebral artery occlusion, CGA directly showed a significantly reduced brain water content, by the inhibitory effects on MMP-2 and MMP-9 activities.

The study also addressed that the attenuation of brain edema may also be resulted by the chemical compound's anti lipid peroxidation (LPO) activity through increased antioxidant expression.

Lipid peroxidation (LPO) is a free radical-related process occurred under enzymatic control, through the activity of oxidative degradation of lipids.

Other study in the investigation of anti-inflammatory activity against carrageenan, PGE(2) and serotonin-induced hind paw edema and 12-O-tetradecanoyl-13-acetate (TPA)-induced mouse ear edema models, chlorogenic acid (CGA), also exerted a significant anti-inflammatory and antinociceptive activity against serotonin-induced hind paw edema and TPA-induced mouse ear edema, researchers at the Gazi University postulated.

Carrageenan is a mixture of polysaccharides extracted from red and purple seaweeds.

Prostaglandin E2 (PGE2) is a conventional medicine used for treatment of pain and inflammation in numbers of disease, including rheumatoid arthritis and osteoarthritis.

12-O-Tetradecanoylphorbol-13-acetate is one of chemical compound used in experiment to induce endogenous superoxide production. In other word, it is a chemical used routinely in enhanced free radical expression for researcher in animal models.

Finally, researchers in the concerns of the caffeine in reduced risk of edema strongly insisted that injection of caffeine induced diminution in the amount of edema in the body cavities was a result of an inhibition of the production of edema and not to an increased absorption of fluid from the serous body cavities.

The findings suggested that coffee may be used as functional and therapeutic beverage for reduced risk and treatment of edema, more studies are necessary to confirm the promising validity.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Protective Effects of Dihydrocaffeic Acid, a Coffee Component Metabolite, on a Focal Cerebral Ischemia Rat Model by Lee K1, Lee BJ2, Bu Y3.(PubMed)
(2) Chlorogenic acid ameliorates brain damage and edema by inhibiting matrix metalloproteinase-2 and 9 in a rat model of focal cerebral ischemia by Lee K1, Lee JS, Jang HJ, Kim SM, Chang MS, Park SH, Kim KS, Bae J, Park JW, Lee B, Choi HY, Jeong CH, Bu Y.(PubMed)
(3) Ethnopharmacological evaluation of some Scorzonera species: in vivo anti-inflammatory and antinociceptive effects by Küpeli Akkol E1, Bahadır Acıkara O, Süntar I, Ergene B, Saltan Çitoğlu G.(PubMed)
(4) STUDIES IN EDEMA : VIII. THE INFLUENCE OF CAFFEINE ON ABSORPTION FROM THE PERITONEAL CAVITY AND THE INFLUENCE OF DIURESIS ON EDEMA by Fleisher MS1, Loeb L.(PubMed)

Saturday, 18 November 2017

Alternative Therapy: Yoga, the Best for Treatment of Patients with Lower Back Pain

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

A recent joint study suggested that yoga participants with chronic lower back pain display a significant improvement on pain intensity in compared to non yoga treatment group.

Yoga is a ancient practical technique of India, included breath control, meditation, bodily movement and gesture,..... with an aim to achieve harmonization of the body, mind, and spirit.

Low back pain is a Musculoskeletal disorders (MSDs) of degenerative disc disease, affecting over 80% of the population in US alone some points in their life.with pain persisted for longer than 3 months,

In a randomized to either yoga or delayed yoga treatment of 150 military veterans in 2013-2015 with outcomes assessed at baseline, 6 weeks, 12 weeks, and 6 months, group attend yoga lessons expressed a greater reductions in Roland-Morris Disability Questionnaire scores than delayed treatment participants at 6 months.

Roland-Morris Disability Questionnaire scores (RMQ) is a questionnaire of 24-item patient-reported outcome and measurement about pain-related disability, in this case, it is lower back pain.

The study also found that treatment group displayed improved more on pain intensity and reduced opioid usage at 12 weeks and at 6 months in compared to delay group.

Opioid is a pain reliever with function to binds to one or more of the three opioid receptors of the body, thus reducing pain.

Dr. Groessl EJ, the lead author said, " Yoga improved health outcomes among veterans despite evidence they had fewer resources, worse health, and more challenges attending yoga sessions than community samples studied previously".

Other, in a parallel randomized controlled trial comparing yoga to education for 120 Veterans with chronic low back pain, yoga treatment group addressed a great positive effects in improved pain score measured by the Defense and Veterans Pain Rating after 24 weeks.

The Defense & Veterans Pain Rating Scale (DVPRS) is a graphic tool of 1-10 McGill pain scale, used to facilitate self-reported pain diagnoses from patients.

Furthermore, the study also found that continuous yoga participation after study not only benefits on physical pain but also showed improved psychological comorbidities.

In support to the above differentiation, the 95 adults recruited from an urban safety-net hospital and five community health centers comparing once-weekly (n = 49) versus twice-weekly (n = 46) standardized yoga classes supplemented by home practice study insisted that there was no differences between once-weekly and twice-weekly groups for pain reduction, but at the 12 weeks, groups with once-weekly or twice-weekly yoga classes exerted the similarly significant efficacy in pain reduction in both group of adults with moderate to severe chronic low back pain.

Truly, evidences in the working population with non-specific low-back pain participated in kundalini yoga at least two times a week, strongly support the effect of yoga in inhibited pain symptom with a significantly reduction in sickness absenteeism.

Kundalini Yoga (kuṇḍalinī-yoga), also known as laya yoga or "the yoga of awareness" is a form of technique used to build physical vitality and increase consciousness through movement, dynamic breathing techniques, meditation, and the chanting of mantras in aid concentration in meditation.


Taking together, yoga may be one of alternative treatment of ancient techniques having a potential effect in reduced pain in patients with lower back pain, please make sure you mention your specific limitation to your instructor before commencing.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN



Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Yoga for Military Veterans with Chronic Low Back Pain: A Randomized Clinical Trial by Groessl EJ1, Liu L2, Chang DG3, Wetherell JL4, Bormann JE5, Atkinson JH4, Baxi S6, Schmalzl L7.(PubMed)
(2) Yoga versus education for Veterans with chronic low back pain: study protocol for a randomized controlled trial by Saper RB1, Lemaster CM2, Elwy AR3,4, Paris R5, Herman PM6, Plumb DN7, Sherman KJ8,9, Groessl EJ10,11, Lynch S12, Wang S7, Weinberg J13.(PubMed)
(3) Comparing Once- versus Twice-Weekly Yoga Classes for Chronic Low Back Painin Predominantly Low Income Minorities: A Randomized Dosing Trial by Saper RB1, Boah AR, Keosaian J, Cerrada C, Weinberg J, Sherman KJ.(PubMed)

Alternative Therapy: Yoga in Enhanced Immune Function

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

 Yoga practicing may have a profound effect in improved immune function against foreign invasion, particularly in age-related immune suppression in elderly individuals

Immune function is a natural reaction of immune system in protected our body against from foreign substances, cells, and tissues through proper expression of immune response.

Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to evaluate the effect of yoga on mucosal immune function and mental stress with saliva samples collected from 23 adult women (age: 60.4 ± 10.4 years) before and after 90 minutes of yoga stretching or rest, researchers found that
1. Yoga group expressed a significant higher immunoglobulin A (SIgA)(a subclass of Immunoglobulin A (IgA) plays an important role in the immune function of mucous membranes)
concentration and secretion rate after yoga than before and in compared to control
2. The levels of cortisol( higher levels cortisol caused by stress has a negative effect in immune system) concentration and secretion rate were lower and testosterone(which plays an important role in immune function in reduced risk of autoimmune disease) secretion rate higher after yoga.
After further analysis and taking into account of other co founders, researcher said, " Yoga stretching can reduce stress and enhance mucosal immune function in elderly women."

Mucosal immune function is a first line of defense of immune system against antigens and infection and in regulated immune over reaction from unharmful sources.

According to general belief, yoga twist, compress and standing posts exercise play an important role in ameliorated alterations in the number of immune cells and cytokine dysregulation through lowering stress hormones production.

Additionally, the exercises also found to improve energy and energy balancing in the body which are necessary for immune system to function properly.

In the concerns of yoga expression in enhanced immune system through numbers of mechanism, researchers at the Daejeon University conducted a study in healthy adults, to highlight the beneficial effects of yoga practice on bio-parameters related to immune expression found that
1. Yoga group expressed a significantly reduced levels of relative oxygen species(ROS), including include peroxides, superoxide, hydroxyl radical, and singlet oxygen through regulating cellular metabolism in production of ROS which have been found to have a direct influence in T cells activation, apoptosis, and immune hypo responsiveness.2. Yoga group demonstrated  a improvement of immunity in increased levels of antioxidant in compared to control, through the effects of free radical scavengers in reduced cellular damage caused by over expression of ROS in inducing inflammation.
3. Yoga practice also significantly increased immune-related cytokines, such as interleukin-12, and interferon-γ,....which play an important role in reduced risk of inflammatory and auto immune diseases, including diabetes, atherosclerosis, rheumatic arthritis, and cancer.
4. The levels of plasma levels of adrenalin was reduced  and serotonin was increased in yoga group in compared with the control group.

Elevation of plasma levels of adrenalin caused by stress may suppress the immune system and increased levels of serotonin showed a opposite effect in increased killing ability of natural killer (NK) cells.
After taking into account of other co founders, Dr. Lim SA, the led researcher said, "Regular yoga practice remarkably attenuated oxidative stress (caused by imbalance of between the production of free radicals and antioxidants) and improved antioxidant levels of the body. Moreover, yoga beneficially affected stress hormone releases as well as partially improved immune function."
More importantly, in the review on the effects of yoga poses on psychological conditions including anxiety and depression, on pain syndromes, cardiovascular, autoimmune and immune conditions and on pregnancy., Dr. Field T, at the University of Miami School of Medicine, opinionated that yoga intervention induced the less production of cortisol, the hormone has a negative effect on immune system due to stress may indeed have a profound effect in enhanced immune cellular function, particularly in psychological conditions in regulating the autoimmune and immune conditions.

Taking altogether, There is no doubt that yoga practice may have a therapeutic effect in improved immune function against from foreign substances, cells, and tissues through numbers of mechanism involving different pathways.

Sources
(1) Yoga stretching for improving salivary immune function and mental stress in middle-aged and older adults by Eda N1, Ito H2, Shimizu K3, Suzuki S4, Lee E4, Akama T1.(PubMed)
(2) Regular Yoga Practice Improves Antioxidant Status, Immune Function, and Stress Hormone Releases in Young Healthy People: A Randomized, Double-Blind, Controlled Pilot Study by Lim SA1, Cheong KJ1.(PubMed)
(3) Yoga clinical research review by Field T1.(PubMed)