Antioxidants: Neurodegenrative diseases - Multiple Sclerosis: The Effects of Antioxidants

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named Health Tweets: The 50 Best Healthy Living And Fitness Tweeters In Canada - Huffington Post
TWEETER: Kyle J.Norton, health researcher and writer 
TWEETS ABOUT: Health articles, industry updates — overall, one source to get several types of health news 
FOLLOW: @kylejnorton
by Huffington Post, Canada
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299..

Human aging is a biological process, no one can stop, but delay it. It is possible that one person has a physiological younger than his or her biological if one engages in healthy living life style and eating healthily by increasing the intake of good healthy food such as whole grain, fruits, vegetables, beans and legumes, etc. and reducing the consumption of harmful foods, such as saturated fat, trans fat, artificial ingredients, etc.

                      

                 Neurodegenrative diseases

Neurodegeneration is defined as a health conditions of the progressive loss of structure or function of neurons, including death of neurons, includingParkinson’s, Alzheimer’s, and Huntington’s diseases due to genetic mutations, most of which are located in completely unrelated genes.

                                        Multiple Sclerosis 

Multiple Sclerosis is an inflammation of central nervous system disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are deterioted, leading to impair of prope conduction of nerve impulse.

                                          The Symptoms

Antioxidants can help protect the neural tissue from damage that reduce the risk of inflammation result in lessening the risk of oxidative stress.
a. TNFalpha
An imflammatory cytokine has been associated with MS is inhibited by antioxidants of green tea, and others such as curcumin, quercetin, etc.

b. Melatonin
Melatonin functions as an antioxidant and has the ability to protect neurons from free radicals cause of lipid peroxidation.

c Selenium
Some studied found that the levels of selenium in the blood of people with MS was lower than in that of people without MS.

d. Niacin
Niacin acts as antioxidant is a key to the successful treatment of multiple sclerosis, researchers at Harvard Medical School found that Niacin profoundly prevents the degeneration of demyelinated axons and improves the behavioral deficits.

e. Vitamin D
A study published in a recent issue of the journal Neurology, the group receiving the vitamin D demonstrated a remarkable 41 percent reduction in new MS events with no meaningful side effects.

f. Etc.
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Antioxidants: Neurodegenrative diseases - Multiple Sclerosis: The Effects of Free radicals

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named Health Tweets: The 50 Best Healthy Living And Fitness Tweeters In Canada - Huffington Post
TWEETER: Kyle J.Norton, health researcher and writer 
TWEETS ABOUT: Health articles, industry updates — overall, one source to get several types of health news 
FOLLOW: @kylejnorton
by Huffington Post, Canada
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Human aging is a biological process, no one can stop, but delay it. It is possible that one person has a physiological younger than his or her biological if one engages in healthy living life style and eating healthily by increasing the intake of good healthy food such as whole grain, fruits, vegetables, beans and legumes, etc. and reducing the consumption of harmful foods, such as saturated fat, trans fat, artificial ingredients, etc.

                      

                 Neurodegenrative diseases

Neurodegeneration is defined as a health conditions of the progressive loss of structure or function of neurons, including death of neurons, includingParkinson’s, Alzheimer’s, and Huntington’s diseases due to genetic mutations, most of which are located in completely unrelated genes.

                                        Multiple Sclerosis 

Multiple Sclerosis is an inflammation of central nervous system disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are deterioted, leading to impair of prope conduction of nerve impulse.

                                          The Effects of Free radicals

a. The DeVine theory suggested that free radical activity is a contributory factors in MS, theory suggestive that immune system and free radical cooperation cause the generation of in the myelin itself that deteriorates the myelin shealts.

b. Cooper theory went on step further by suggested that free radicals actually initiate MS, by damaging the myelin, leading to initiating and promoting of activity of T-cells.

c. Etc.

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesityand restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Regular Walking Reduces Risk and Complications of Hypertension in Older Adults

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named Health Tweets: The 50 Best Healthy Living And Fitness Tweeters In Canada - Huffington Post
TWEETER: Kyle J.Norton, health researcher and writer 
TWEETS ABOUT: Health articles, industry updates — overall, one source to get several types of health news 
FOLLOW: @kylejnorton
by Huffington Post, Canada
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.



Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. High blood pressure means raising pressure in your heart.If it stays high over time it can damage the body in many ways.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects such as damaging the kidney. If you can control your diet, such as making changes to lifestyle, maintaining ideal weight and diet with low salt, you could do just fine without the drugs. According to the UT Southwestern Medical Center, prevalent users of high blood pressure medications were recovered after long term of maximal exercise(1).

But there is a concern of experts in the discontinued intake of medication contributed to risks of macrovascular events, microvascular events together and separately and all-cause mortality(2).


The 2008 joint study of a total of 4294773 patients diagnosed with hypertension and subsequently prescribed anti-hypertensive medications led by the University College of Medicine, suggested the importance of medication adherence (MA) and the incidence of complications in patients with newly diagnosed hypertension because of its highly prevalent rate of complications(4).

Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of reduced risk and complications of hypertension in the younger and older elderly have been lacking, probably due to the effectiveness of modern medication in syndrome of controlling (3).

Does regular walking reduces risk of hypertension?
Dr. Okura T and colleagues at the Ehime University Graduate School of Medicine insisted, regular physical activity (PA), including daily walking, not only reduces the risk of many chronic diseases, especially hypertension" but also induces the controlled BP in hypertensive patients."(5).

The review of 2246 citations; 26 studies with a total of 2767 participants also suggested that the use of a pedometer is associated with significant increases in physical activity and significant decreases in body mass index and blood pressure(6).


Does regular walking reduces risk of hypertension complications?

A randomized controlled trial (RCT) led by the David Geffen School of Medicine at UCLA showed that a culturally-tailored community-based walking reduces stroke risk by increasing physical activity among African American, Latino, Chinese, and Korean seniors with hypertension(7).


Dr. Pugh D said, " regular exercise can produce up to a 30% reduction in all cause mortality with a 35% lower risk of cardiovascular disease, coronary heart disease and stroke" and "There is evidence to show that 37% of CHD deaths can be attributed to physical inactivity compared with 19% and 13% for smoking hypertension respectively"(8).

Taking altogether, there are strong evidences to suggest that regular walking Reduces Risk and Complications of Hypertension patients with or without syndrome of hypertension, particular in Older Adults populations.


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References
(1) Heart Rate Recovery and Systolic Blood Pressure Recovery After Maximal Exercise in Prevalent Users of Stimulant Medications by Westover AN1, Nakonezny PA, Barlow CE, Adinoff B, Brown ES, Halm EA, Vongpatanasin W, DeFina LF.(PubMed)
(2) Risks associated with permanent discontinuation of blood pressure-lowering medications in patients with type 2 diabetes by Hirakawa Y1, Arima H, Webster R, Zoungas S, Li Q, Harrap S, Lisheng L, Hamet P, Mancia G, Poulter N, Neal B, Williams B, Rogers A,Woodward M, Chalmers J.(PubMed)
(3) Examining the relationship between antihypertensive medication satisfaction and adherencein older patients by Al-Ruthia YS1, Hong SH2, Graff C3, Kocak M4, Solomon D5, Nolly R6.(PubMed)
(4) Medication Adherence and the Occurrence of Complications in Patients with Newly Diagnosed Hypertension by Kim HJ1, Yoon SJ2, Oh IH3, Lim JH3, Kim YA4.(PubMed)
(5) The Importance of Walking for Control of Blood Pressure: Proof Using a Telemedicine System by Okura T1, Enomoto D2, Miyoshi KI1, Nagao T1, Kukida M1, Akiko T1, Pei Z1, Higaki J1, Uemura H3.(PubMed)
(6) Using pedometers to increase physical activity and improve health: a systematic review by Bravata DM1, Smith-Spangler C, Sundaram V, Gienger AL, Lin N, Lewis R, Stave CD, Olkin I, Sirard JR.(PubMed)
(7) Study protocol of "Worth the Walk": a randomized controlled trial of a stroke risk reductionwalking intervention among racial/ethnic minority older adults with hypertension in community senior centers by Kwon I1, Choi S2, Mittman B3, Bharmal N4, Liu H5, Vickrey B6, Song S7, Araiza D8, McCreath H9, Seeman T10, Oh SM11, Trejo L12,Sarkisian C13(PubMed)
(8) Time to encourage patients to take more exercise by Pugh D1.(PubMed)

Regular Walking Reduces Risk of Over Weight and visceral or subcutaneous fat accumulation in Older Adults

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named Health Tweets: The 50 Best Healthy Living And Fitness Tweeters In Canada - Huffington Post
TWEETER: Kyle J.Norton, health researcher and writer 
TWEETS ABOUT: Health articles, industry updates — overall, one source to get several types of health news 
FOLLOW: @kylejnorton
by Huffington Post, Canada
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Visceral or subcutaneous fat accumulation is fat accumulated in the abdominal area, leading to higher risk of insulin resistance, and its concomitant metabolic disorders (the metabolic syndrome) including atherogenic dyslipidemia(1), in comparison to those with less visceral fat accumulation.

Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of reduced risk of visceral or subcutaneous fat accumulation in the younger and older elderly have been lacking, probably due to its association to complication of obesity(2).


The study of total of 173 sedentary, overweight (body mass index > or =24.0 and >33% body fat), postmenopausal women aged 50 to 75 years who were living in the Seattle, Wash, area, suggested, Walking reduced body weight and body fat among overweight and obese postmenopausal women.as it was the most frequently reported activity in the group(3).

Dr. Lynch NA and colleagues at the University of Maryland School of Medicine insisted that walking not only is associated with greater reductions in visceral adiposity in obese postmenopausal women but also improved in maximal O(2) uptake (VO(2 max)(4) of that is said to significantly improve the metabolic profile(5).

In fact, regular walking is found to reduce risk of visceral or subcutaneous fat accumulation as it prevents the early state of weigh gain.

The Okayama Southern Institute of Health in the study of Thirty one obese Japanese males (body mass index (BMI) > or = 25) ranging in age from 32 to 59, participated in a 1-year follow up study said, " intra-abdominal visceral adipose tissue is critically involved in insulin resistance and daily walking rather than improvement of exercise capacity correlated with the reduction of visceral adipose tissue in obese Japanese males."(6). As walking significantly lowers serum leptin concentrations(8), and thus it may improve the leptin resistance observed in overweight adults(7).

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The Best Way to prevent, treat your disease,
particular in treatment of Musculoskeletal disorders

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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References
(1) Obesity and dyslipidemia in South Asians by Misra A1, Shrivastava U.(PubMed)
(2) [Systolic pressure, abdominal obesity and body fat, metabolic syndrome predictors in Spanish preschoolers].[Article in Spanish] by Gutiérrez Hervás AI1, Rizo Baeza MM2, Martínez Amorós N3, Cortés Castell E4.(PubMed)
(3) Effect of exercise on total and intra-abdominal body fat in postmenopausal women: a randomized controlled trial by Irwin ML1, Yasui Y, Ulrich CM, Bowen D, Rudolph RE, Schwartz RS, Yukawa M, Aiello E, Potter JD, McTiernan A.(PubMed)
(4) Reductions in visceral fat during weight loss and walking are associated with improvements in VO(2 max) by Lynch NA1, Nicklas BJ, Berman DM, Dennis KE, Goldberg AP.(PubMed)
(5) Is there a threshold of visceral fat loss that improves the metabolic profile in obese postmenopausal women? by Brochu M1, Tchernof A, Turner AN, Ades PA, Poehlman ET.(PubMed)
(6) Daily walking reduces visceral adipose tissue areas and improves insulin resistance in Japanese obese subjects by Miyatake N1, Nishikawa H, Morishita A, Kunitomi M, Wada J, Suzuki H, Takahashi K, Makino H, Kira S, Fujii M.(PubMed)
(7) Physical activity is associated with risk factors for chronic disease across adult women's life cycle by Woolf K1, Reese CE, Mason MP, Beaird LC, Tudor-Locke C, Vaughan LA.(PubMed)
(8) Moderate physical activity permits acute coupling between serum leptin and appetite-satiety measures in obese women by Tsofliou F1, Pitsiladis YP, Malkova D, Wallace AM, Lean ME.(PubMed)

Regular Walking Reduces Symptoms and Risk of Low Back Pain in Population of 50plus?

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named Health Tweets: The 50 Best Healthy Living And Fitness Tweeters In Canada - Huffington Post
TWEETER: Kyle J.Norton, health researcher and writer 
TWEETS ABOUT: Health articles, industry updates — overall, one source to get several types of health news 
FOLLOW: @kylejnorton
by Huffington Post, Canada
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.



Chronic back pain is a significant problem worldwide. According to statistic, Low back pain is a Musculoskeletal disorders (MSDs, affecting over 80% of the population in US alone some points in their life. Chronic LBP (pain has persisted for longer than 3 months(5) prevalence in older adults was significantly higher than the 21-to-44-year age group

Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of health benefits of low back pain in the younger and older elderly have been lacking, probably due to body height and weight and other parameters(1), such as psychosocial factors(4).As available evidence on the association between physical activity (i.e. occupational load and non-occupational physical activities) and low back pain (LBP)(3).


But according to the review of the 2583 initially identified articles, 121 articles analyzed conducted by Fédération hospitalo-universitaire de médecine physique et de réadaptation Montpellier-Nîmes, suggested, " Moderate but regular physical activity( included walking) helps to improve fitness and does not increase the risk of acute pain in chronic LBP patients"(2).
In fact, in a systematic review of studies using pedometers, Dr. Mansi S and colleagues at the University of Otago said, ".....strong evidence for the effectiveness of pedometer walking interventions in increasing PA levels for patients with MSDs", using 11 electronic databases up to 20 February 2014(7).
In support of the effect of exercise, including walking the VA Ann Arbor Healthcare System insisted that exercise is an integral part of managing chronic back pain but to be effective requires that patients actively participate in the management process(6).


Does regular walking reduce risk of low back pain? the Cooper River Bridge Run Study said, "runners and walkers may have a lower relative risk for significant LBP" and " Prevalence of LBP at the time of survey completion was 13.6%"(9)in this population in comparison to general statistic.
In deed, walking 4 to 7 days per week is found to reduce the risk of LB disability onset by 50% to 80% on the older Black adults and 50% on older White adults(8), respectively.


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particular in treatment of Musculoskeletal disorders



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References
(1) Physical activity and low-back pain in schoolchildren by Skoffer B1, Foldspang A.(PubMed)
(2) Which physical activities and sports can be recommended to chronic low back pain patients after rehabilitation? by Ribaud A1, Tavares I, Viollet E, Julia M, Hérisson C, Dupeyron A.(PubMed)
(3) Physical activity and low back pain: a systematic review of recent literature by Heneweer H1, Staes F, Aufdemkampe G, van Rijn M, Vanhees L.(PubMed)
(4) Low back pain in schoolchildren: the role of mechanical and psychosocial factors by Watson KD1, Papageorgiou AC, Jones GT, Taylor S, Symmons DP, Silman AJ, Macfarlane GJ.(PubMed)
(5) Management of chronic low back pain by Nikolai Bogduk
(6) Veterans walk to beat back pain: study rationale, design and protocol of a randomized trial of a pedometer-based internet mediated intervention for patients with chronic low back pain by Krein SL1, Metreger T, Kadri R, Hughes M, Kerr EA, Piette JD, Kim HM, Richardson CR.(PubMed)
(7) A systematic review of studies using pedometers as an intervention for musculoskeletal diseases by Mansi S1, Milosavljevic S, Baxter GD, Tumilty S, Hendrick P.(PubMed)
(8) The effect of walking on lower body disability among older blacks and whites by Clark DO1.(PubMed)
(9) The Cooper River Bridge Run Study of low back pain in runners and walkers by Woolf SK1, Barfield WR, Nietert PJ, Mainous AG 3rd, Glaser JA.(PubMed)

Regular Walking Reduces Symptoms and Risk of Polymyalgia Rheumatica in Population of 50plus?

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named Health Tweets: The 50 Best Healthy Living And Fitness Tweeters In Canada - Huffington Post
TWEETER: Kyle J.Norton, health researcher and writer 
TWEETS ABOUT: Health articles, industry updates — overall, one source to get several types of health news 
FOLLOW: @kylejnorton
by Huffington Post, Canada
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of health benefits of Polymyalgia Rheumatica in the younger and older elderly have been controversial.


Polymalgia Arthritis is a condition a common inflammatory rheumatic disease causeing pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

According to the Saint-André Hospital, Bordeaux Teaching Hospital, there has been a report of 2 cases of inflammatory arterial lesions of the lower limbs as results of intermittent claudication with a walking distance of only 30 m(1).

But regular walking has shown. to improve immunity against inflammation(2), through reduction of oxidative stress(4) and production of inflammatory cytokines (reduction in the ratio of plasma IL-6 to IL-10 levels)(3), through improved immune and inflammatory responses(3).
Dr. Dopheide JF and colleagues at the University Medical Center of the Johannes Gutenberg-University Mainz said, "a reduced inflammatory state might be achieved by regular walking exercise" and " amelioration of the proinflammatory phenotype"(2)

Walking caused modest and short-lived changes in immune parameters, most notably for neutrophil and natural killer blood cell counts through increased oxygen comsumption(6).

In fact regular exercise, including walking effecting the levels of inflammatory cytokine can contribute to guide clinical practice related to treatment and prevention of functional changes due to chronic inflammatory activity in older adults(4).

On the total of 297 healthy adults ages 50-79 years with no history of knee injury or disease recruited from an existing study on healthy aging, insisted, regular walking reduces the risk of bone marrow lesions in the knee. and may be a beneficial effect of physical activity for diseases associated with aging and exercise that is good for the heart is also good for the knees(5).
The Medical Disability Advisor in the evaluation of Polymyalgia Rheumatica suggested that patients with Polymyalgia Rheumatica should have developed a realistic and comprehensive program of walking, aquatic exercise, stretching, and strengthening exercises(7).

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The Best Way to prevent, treat your disease,
particular in treatment of Musculoskeletal disorders


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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Reference
(1) Giant cell arteritis involving the lower limbs by Dupuy R1, Mercié P, Neau D, Longy-Boursier M, Conri C.(PubMed)
(2) Change of walking distance in intermittent claudication: impact on inflammation, oxidative stress and mononuclear cells: a pilot study by Dopheide JF1, Scheer M, Doppler C, Obst V, Stein P, Vosseler M, Abegunewardene N, Gori T, Münzel T, Daiber A, Radsak MP, Espinola-Klein C.(PubMed)
(3) Evidence for anti-inflammatory effects of exercise in CKD BY Viana JL1, Kosmadakis GC2, Watson EL3, Bevington A3, Feehally J2, Bishop NC4, Smith AC5.(PubMed)
(4) Interaction between cytokine gene polymorphisms and the effect of physical exercise on clinical and inflammatory parameters in older women: study protocol for a randomized controlled trial. by Pereira DS1, Queiroz BZ, Mateo EC, Assumpção AM, Felício DC, Miranda AS, Anjos DM, Jesus-Moraleida F, Dias RC, Pereira DA,Teixeira AL, Pereira LS.(PubMed)
(5) Effect of physical activity on articular knee joint structures in community-based adults.Racunica TL1, Teichtahl AJ, Wang Y, Wluka AE, English DR, Giles GG, O'Sullivan R, Cicuttini FM.(PubMed)
(6) Immune response to a 30-minute walk by Nieman DC1, Henson DA, Austin MD, Brown VA.(PubMed)
(7) Medical Disability Advisor > Polymyalgia Rheumatica(GMD Guideline)

A balance of Regular Walking and Rest Reduce Symptoms of Polymalgia Arthritis(PMR) in Population of 50plus

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named Health Tweets: The 50 Best Healthy Living And Fitness Tweeters In Canada - Huffington Post
TWEETER: Kyle J.Norton, health researcher and writer 
TWEETS ABOUT: Health articles, industry updates — overall, one source to get several types of health news 
FOLLOW: @kylejnorton
by Huffington Post, Canada
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of health benefits of reduced symptoms of Polymalgia Arthritis in the younger and older elderly have been controversial.

Polymalgia Arthritis is defined as a condition a common inflammatory rheumatic disease which cause pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdleas a result of the presence of a synovitis in proximal joints and periarticular structures, causing musculoskeletal symptoms in PMR.

Regular exercise, including walking is essential for maintaining joint flexibility, muscle strength and function, according to American Arthritis foundation(1).
Arthritis Research UK said, "Weight-bearing exercise (any exercise that involves walking or running) is best for maintaining bone strength and guarding against osteoporosis, but walking is usually most suitable for people with PMR"(2).

In fact, according to Arthritis Research UK on polymyalgia rheumatica, the key is to strike a balance, as walking may help reduce pain and will keep muscles from becoming weak.  Too much activity (which can strain painful muscles), and too little activity (which can increase pain and stiffness and lead to further weakness)(3).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Polymyalgia Rheumatica, American Arthritis foundation
(2) Self-help and daily living for polymyalgia rheumatica (PMR),
(3) Condition polymyalgia rheumatica(PMR) by Arthritis Research UK