Monday, 13 June 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The Phytochemicals: Resveratrol

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

The  Phytochemicals

Different mediators of central inflammation in dysfunctional and inflammatory pain have been found to associate with patient with Fibromyalgia(127). Certain phytochemicals have found effectively for treatment of inflammatory symptoms of patient with FM, including the following

3. Resveratrol
Resveratrol (RES), a well-known antioxidant and anti-inflammatorycompound, is abundant in red wine and exerts numerous pharmacological effects, including hepatoprotection and cadioprotection(137).
The antioxidant exhibited anti-inflammatory effects through ameliorated the expression of proinflammatory (e.g., miR-155) in infections, injuries, atherosclerosis, diabetes mellitus, obesity, cancer, osteoarthritis, age-related macular degeneration, demyelination, and neurodegenerative diseases(138).
In the evaluation of the medical effect of resveratrol, the University of Wuxi, Jiangsu, insisted" Resveratrol prevented the accumulation of chronic oxidative stress and suppression of Tregs production in HFD mice, modulated changes of cytokines in the plasma and spleen, and decreased expressions of inflammatory mediators compared with those of the DIO group"(139).
Furthermore, the antioxidant also expressed anti age-associated chronic diseases through exhibited dysregulation of multiple cell signaling pathways in induction of inflammation(140).According to the University of Arizona study, resveratrol facilitated acute and chronic pain through activation of AMPK, the enzyme played a key role as a master regulator of cellular energy homeostasis(141).
In a Mouse Fibromyalgia-Like Model, resveratrol significantly reduced mechanical allodynia and thermal hyperalgesia in attenuated oxidative stress and reactive species, underlying mechanism of pathogenesis of the disease. through antinociceptive and antidepressant actions(142)

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and restore your health naturally with Chinese diet

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References
(137) Resveratrol nanoparticle system improves dissolution properties and enhances the hepatoprotective effect of resveratrol through antioxidant and anti-inflammatory pathways by Lee CW1, Yen FL, Huang HW, Wu TH, Ko HH, Tzeng WS, Lin CC.(PubMed)
(138) Exploring new ways of regulation by resveratrol involving miRNAs, with emphasis on inflammation by Latruffe N1, Lançon A1, Frazzi R2, Aires V1,3, Delmas D1,3, Michaille JJ1, Djouadi F4, Bastin J4, Cherkaoui-Malki M1.(PubMed)
(139) Resveratrol prevents suppression of regulatory T-cell production, oxidative stress, and inflammation of mice prone or resistant to high-fat diet-induced obesity by Wang B1, Sun J, Li X, Zhou Q, Bai J, Shi Y, Le G.(PubMed)
(140) Resveratrol: a multitargeted agent for age-associated chronic diseases by Harikumar KB1, Aggarwal BB.(PubMed)
(141) Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain by Tillu DV1, Melemedjian OK, Asiedu MN, Qu N, De Felice M, Dussor G, Price TJ.(PubMed)
(142) Coadministration of Resveratrol and Rice Oil Mitigates Nociception and Oxidative State in a Mouse Fibromyalgia-Like Model by Peres Klein C1, Rodrigues Cintra M2, Binda N3, Montijo Diniz D3, Gomez MV3, Souto AA4, de Souza AH5.(PubMed)

Sunday, 12 June 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The Phytochemicals: Curcumin

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                 
 The  Phytochemicals

Different mediators of central inflammation in dysfunctional and inflammatory pain have been found to associate with patient with Fibromyalgia(127). Certain phytochemicals have found effectively for treatment of inflammatory symptoms of patient with FM, including the following
2. Curcumin
Curcumin, a phytochemical found in turmeric used in the Indian cooking recipe has found to process the antioxidants and anti inflammatory effects, epidemiologically.
The phytochemical also showed to inhibited muscle pain, muscle damage, inflammation and delayed onset muscle soreness, the SportsMed Canterbury study suggested.(132), through attenuate the inflammatory responses and production of reactive oxygen species (ROS) that sustain both inflammation and oxidative stress(133).
Dr. Ghosh S and colleagues at the Bose Institute suggested, " Oxidative stress and inflammation play a pivotal role in various diseases like diabetes, cancer, arthritis, Alzheimer's disease and cardiovascular diseases. Curcumin, therefore, could be a therapeutic option for the treatment of these diseases, provided limitations in its oral bioavailability can be overcome."(134), particular in various proinflammatory chronic diseases(135).In fact Dr. Anand P and the research team at the University of Texas M.D. Anderson Cancer Center, curcumin beside inhibited pain in many therapeutic levels but also linked to suppression of inflammation; angiogenesis, tumorigenesis and diseases of the cardiovascular, pulmonary, and neurological systems(136).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods LibraryEat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(132) Curcumin supplementation likely attenuates delayed onset muscle soreness (DOMS) by Nicol LM1, Rowlands DS, Fazakerly R, Kellett J.(PubMed)
(133) Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial by Drobnic F1, Riera J1, Appendino G2, Togni S3, Franceschi F3, Valle X4, Pons A5, Tur J5.(PubMed)
(134) The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update by Ghosh S1, Banerjee S1, Sil PC2.(PubMed)
(135) Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases by Aggarwal BB1, Harikumar KB.(PubMed)
(136) Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature.by Anand P1, Thomas SG, Kunnumakkara AB, Sundaram C, Harikumar KB, Sung B, Tharakan ST, Misra K, Priyadarsini IK, Rajasekharan KN, Aggarwal BB.(PubMed)


Saturday, 11 June 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The Phytochemicals: Polyphenols(-)-epigallocatechin-3-gallate (EGCG)

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                  The  Phytochemicals

Different mediators of central inflammation in dysfunctional and inflammatory pain have been found to associate with patient with Fibromyalgia(127). Certain phytochemicals have found effectively for treatment of inflammatory symptoms of patient with FM, including the following

1. Polyphenols(-)-epigallocatechin-3-gallate (EGCG)(Green tea)
Epigallocatechin gallate (EGCG), including catechins, is phytochemicals of Flavan-3-ols, in the group of Flavonoids (polyphenols) found abundantly catechin in green tea.The majoe phytochemical has showed to process anti viral and bacterial effects through immune expression such as chronic or acute inflammation(128). Dr. Xiao J and the research team at the Shenzhen Institute of Advanced Technology suggested, pure extract of (-) epigallocatechin gallate (EGCG) inhibited inflammatory effects through its antioxidant activities against oxidative stress and down regulated pro-inflammatory markers(129).
According to the Universitat de Girona (UdG), Polyphenols(-)-epigallocatechin-3-gallate (EGCG) also showed to reduce pain in attenuate the alterations by diminishing apoptotic gene overexpression in skeletal muscles(130).
In the consideration of the safety amount for healthy individuals to take green tea, Dr. Chow HH and colleagues said, "green tea polyphenol products in amounts equivalent to the EGCG content in 8-16 cups of green tea once a day or in divided doses twice a day for 4 weeks. There is a >60% increase in the systemic availability of free EGCG after chronic green tea polyphenol administration at a high daily bolus dose (800 mg EGCG or Polyphenon E once daily)(131).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods LibraryEat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(127) Evidence of different mediators of central inflammation in dysfunctional and inflammatory pain--interleukin-8 infibromyalgia and interleukin-1 β in rheumatoid arthritis by Kosek E1, Altawil R2, Kadetoff D3, Finn A4, Westman M2, Le Maître E2, Andersson M5, Jensen-Urstad M6, Lampa J2.(PubMed)
(128) Compounds derived from epigallocatechin-3-gallate (EGCG) as a novel approach to the prevention of viral infections by Hsu S.(PubMed)
(129) Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways by Xiao J1, Ho CT, Liong EC, Nanji AA, Leung TM, Lau TY, Fung ML, Tipoe GL.(PubMed)
(130) (-)-Epigallocatechin-3-gallate (EGCG) attenuates functional deficits and morphological alterations by diminishing apoptotic gene overexpression in skeletal muscles after sciatic nerve crush injury by Renno WM1, Al-Maghrebi M, Al-Banaw A(PubMed)).
(131) Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals by Chow HH1, Cai Y, Hakim IA, Crowell JA, Shahi F, Brooks CA, Dorr RT, Hara Y, Alberts DS.(PubMed)



Friday, 10 June 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The diet of Circuit fruits

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                  The diet

Dietary consumption plays an important part in reduce or increase risk of chronic inflammatory diseases. A typical American diet with high amount of red meat, fat and trans fat, processed, meat, artificial ingredients, refined products are associated to promote the expression of pro inflammatory cytokines, leading to all kinds of diseases including chronic inflammatory, cardiovascular diseases and diabetes.
4. Circuit fruits
Circuit fruit contain high amount of Quercetin which can reduce the risk of chronic inflammatory diseases as a result of anti inflammatory(122) and antioxidant effects(123). Vitamin C, also known as L-ascorbate is a water soluble vitamin with a chemical structure formula of C6H6O6 found abundantly in circuit fruit, enhanced the activation of immune cells such as T and NK cells in attenuation of the inflammation caused by viral infection when used conjunction with red ginseng(124).
Dr. Yan H and colleagues in the study of Ascorbic acid (AA) in mitigating oxidative stress and inhibiting inflammation suggested, ascorbic acid significantly reduced clinical signs, inflammatory cytokines, myeloperoxidase (MPO) and malonaldehyde (MDA) activities in animal model(125).
Furthermore, the application of vitamin C and Quercetin, in exposure to fine particulate matter (PM2.5), exhibited the repressive roles in respiratory oxidative damage caused by PM2.5, through attenuated the depleted the cell viability of 16HBE cells, the elevated reactive oxygen species (ROS) generation, and the inhibited mitochondrial genes expressions(126).
                     
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods LibraryEat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(122) In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway by Comalada M1, Camuesco D, Sierra S, Ballester I, Xaus J, Gálvez J, Zarzuelo A.(PubMed)
(123) Health effects of quercetin: from antioxidant to nutraceutical by Boots AW1, Haenen GR, Bast A.(PubMed)
(124) Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection by Kim H1,2, Jang M1, Kim Y1, Choi J1, Jeon J1, Kim J3, Hwang YI1, Kang JS1,2, Lee WJ1.(PubMed)
(125) Ascorbic acid ameliorates oxidative stress and inflammation in dextran sulfate sodium-induced ulcerative colitis in mice by Yan H1, Wang H2, Zhang X3, Li X1, Yu J1.(PubMed)
(126) Amelioration of particulate matter-induced oxidative damage by vitamin c and quercetin in human bronchial epithelial cells by Jin X1, Su R1, Li R2, Song L1, Chen M1, Cheng L3, Li Z4.(PubMed)


Thursday, 9 June 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The diet of Olive oil

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                 The diet

Dietary consumption plays an important part in reduce or increase risk of chronic inflammatory diseases. A typical American diet with high amount of red meat, fat and trans fat, processed, meat, artificial ingredients, refined products are associated to promote the expression of pro inflammatory cytokines, leading to all kinds of diseases including chronic inflammatory, cardiovascular diseases and diabetes.

3. Olive oil
Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is a source of olive oil.

Consumption of extra virgin olive oil (EVOO) has been found to decrease joint edema, cell migration, cartilage degradation and bone erosion throguh attenuate the levels of proinflammatory cytokines and prostaglandin E2(114). according joint study by the University of Seville.In adult male Balb/C mice study, olive oil decreased the second phase of formalin-induced pain through its antinociceptive and anti-inflammatory activity(115).
The Chemistry and health of olive oil phenolics study also found, the positive effects of olive oil phenolics on certain physiological parameters, such as plasma lipoproteins, oxidative damage, inflammatory markers, platelet and cellular function, etc,.....(116).
Omega 3 fatty acids found abundantly in olive, according to university if Toronto exhibited anti neuropathic pain activities(117) and suggested that the oil fatty acids may be used for management of symptoms in patients with fibromyalgia(118).
Dr. Ozgocmen S and colleagues at the Firat University said, " patients with FM are under oxidative stress" and "These findings represent a rationale for further research assessing the effect of free radical scavengers or antioxidant agents like vitamins and omega-3 fatty acids on peripheral and central mechanisms in FM.
In the evaluation of the oxidant/antioxidant status, lipid peroxidation and nitric oxide (NO) in untreated fibromyalgia (FM) patients and controls(119).

Similar to olive, nuts and seeds with rich in Omega 3 fatty acids is necessary to reduce risk of expressionless of markers of inflammation to attenuate the inflammatory response of the immune system, according to the study by the Tufts University(120).
High saturated fat diets with low omega 3 fatty acid intake increased omega-6:EPA+DHA ratio diets causing some measures of inflammation(121).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods LibraryEat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(114) Anti-inflammatory and joint protective effects of extra-virgin olive-oil polyphenol extract in experimental arthritis by Rosillo MÁ1, Alcaraz MJ2, Sánchez-Hidalgo M1, Fernández-Bolaños JG3, Alarcón-de-la-Lastra C1, Ferrándiz ML4.(PubMed)
(115) Antinociceptive and anti-inflammatory effects of olive oil (Olea europeae L.) in mice. by Eidi A1, Moghadam-kia S, Moghadam JZ, Eidi M, Rezazadeh S.(PubMed)
(116) Chemistry and health of olive oil phenolics by Cicerale S1, Conlan XA, Sinclair AJ, Keast RS.(PubMed)
(117) Omega-3 fatty acids for neuropathic pain: case series by Ko GD1, Nowacki NB, Arseneau L, Eitel M, Hum A.(PubMed)
(118) Effect of omega-3 fatty acids in the management of fibromyalgia syndrome by Ozgocmen S, Catal SA, Ardicoglu O, Kamanli A.(PubMed)
(119) Antioxidant status, lipid peroxidation and nitric oxide in fibromyalgia: etiologic and therapeutic concerns by Ozgocmen S1, Ozyurt H, Sogut S, Akyol O, Ardicoglu O, Yildizhan H.(PubMed)
(120) In vitro fatty acid enrichment of macrophages alters inflammatory response and net cholesterol accumulation by Wang S1, Wu D, Lamon-Fava S, Matthan NR, Honda KL, Lichtenstein AH.(PubMed)
(121) Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse by Wang S1, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH.(PubMed)

Wednesday, 8 June 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The diet of Green tea

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                The diet

Dietary consumption plays an important part in reduce or increase risk of chronic inflammatory diseases. A typical American diet with high amount of red meat, fat and trans fat, processed, meat, artificial ingredients, refined products are associated to promote the expression of pro inflammatory cytokines, leading to all kinds of diseases including chronic inflammatory, cardiovascular diseases and diabetes.

2. Green tea
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world.
According to the survey of a complementary and alternative medical therapies by patients referred to a fibromyalgia treatment program at a tertiary care center., green tea has been used in 24% of patients(110).
Green tea polyphenols (GTP) has an effectiveness against chronic inflammation through attenuating the deterioration of bone microarchitecture, according to the Texas Tech University Health Sciences Center, in animal study(111).
Also in rat study, alcoholic extracts of green tea (AE) exhibited its analgesic and anti-inflammatory properties, through inhibited carrageenan-induced cell migration(112).
Decaffeinated dreen tea also expressed the immunomodulatory effects through enhanceing the immune system against inflammatory disease in rainbow trout(113).
Furthermore, in a study of forty-three of fifty-eight (74.1%) female patients with fibromyalgia completed an eight-week treatment period testing the combination of carisoprodol, paracetamol (acetaminophen) and caffeine versus placebo, found that the combination of carisoprodol and paracetamol (acetaminophen) and caffeine (from green tea) are effective in the treatment of fibromyalgia(113a).
     
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods LibraryEat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(110) Use of complementary and alternative medical therapies by patients referred to a fibromyalgia treatment program at a tertiary care center by Wahner-Roedler DL1, Elkin PL, Vincent A, Thompson JM, Oh TH, Loehrer LL, Mandrekar JN, Bauer BA.(PubMed)
(111) Green tea polyphenols attenuate deterioration of bone microarchitecture in female rats with systemic chronicinflammation. by Shen CL1, Yeh JK, Samathanam C, Cao JJ, Stoecker BJ, Dagda RY, Chyu MC, Dunn DM, Wang JS.(PubMed)
(112) Evaluation of the anti-inflammatory and analgesic effects of green tea (Camellia sinensis) in mice by Mota MA1, Landim JS1, Targino TS1, Silva SF1, Silva SL1, Pereira MR1(PubMed)
(113) Immunomodulatory effects of decaffeinated green tea (Camellia sinensis) on the immune system of rainbow trout (Oncorhynchus mykiss). by Sheikhzadeh N1, Nofouzi K, Delazar A, Oushani AK.(PubMed)
(113a) Treatment of fibromyalgia (fibrositis syndrome): a parallel double blind trial with carisoprodol, paracetamol and caffeine (Somadril comp) versus placebo by Vaerøy H1, Abrahamsen A, Førre O, Kåss E.(PubMed)


Monday, 6 June 2016

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia - Other Preventions and Managements

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                 Prevention and Management

The Do and do not’s list
5. Increase in take of anti inflammatory foods, such as fresh vegetables and fruits, seeds and sprouts whole grain, fish, turkey, chicken, legumes, etc(97).

6. Stop smoking
In comparison to non smokers, smokers with fibromyalgia may have greater pain intensity and function impairment(101)(102). Dr. Goesling J and colleagues at the joint study led by the University of Michigan, said, "Although FM+ smokers report the most negative clinical symptomatology (i.e., high pain, greater interference)smoking does not appear to have a unique association with pain or functioning in FM+ patients, rather the effect is additiv"(102)

7. Moderate exercise
Moderate exercise enhances immune function in fighting against inflammation and and reduced inflammatory (interleukin-6 [IL-6], C-reactive protein [CRP]) markers of that attenuate to risk of
Fibromyalgia(103). A single sessions of moderate cycling can improve the inflammatory status and decrease in the stress response in FM patients, according to the University of Extremadura(104), paticular in regular aquatic exercise in FM syndrome(105).

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References
(101) The Perception of Female Smokers with Fibromyalgia on the Effects of Smoking on Fibromyalgia Symptoms by Weingarten TN1, Vincent A2, Luedtke CA3, Beebe TJ4, Welch TL1, Chong EY5, Schroeder DR4, Warner DO1.(PubMed)
(102) Associations Between Pain, Current Tobacco Smoking, Depression, and Fibromyalgia Status Among Treatment-Seeking Chronic Pain Patients by Goesling J1, Brummett CM1, Meraj TS2, Moser SE1, Hassett AL1, Ditre JW3.(PubMed)
(103) A Systematic Review of the Acute Effects of Exercise on Immune and Inflammatory Indices in Untrained Adults by Brown WM1, Davison GW1, McClean CM1, Murphy MH1.(PubMed)
(104) Fibromyalgia: anti-inflammatory and stress responses after acute moderate exercise by Bote ME1, Garcia JJ, Hinchado MD, Ortega E.(PubMed)
(105) An exploratory study of the effect of regular aquatic exercise on the function of neutrophils from women withfibromyalgia: role of IL-8 and noradrenaline by Bote ME1, García JJ1, Hinchado MD1, Ortega E2.(PubMed)