Tuesday, 29 March 2016

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Individual herbs - Valerian

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                     

                  Polymyalagia Arthritis (Rheumatica)



Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.                                  

                                 Treatments

B.2. Herbal and Traditional Chinese medicine 
Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including 
B.2.1. Individual herb
3. Valerian
Valerian is a perennial flowering plant, in the genus Valeriana, belongings to the family Valerianaceae, native to Europe and parts of Asia  used in traditional herbal medicine as a sedative and relaxing agent and to treat the liver, the urinary tract, the digestive tract problem, nerve conditions, etc.,...According to the University of Peshawar, Valerian expressed anti inflammatory effect on the acute and chronic phase inflammation models in male Wistar rats, on dose dependant manner(202), particular in crude extract at a dose of 200 mg/kg at all observed durations(203).
According to the University of Washington, Valerian may be used as sedative in reduced sleep(200) disturbance of patients induced fatigue(201) with inflammatory rheumatic pain(200).

(200) A feasibility study of valerian extract for sleep disturbance in person with arthritis by Taibi DM1, Bourguignon C, Gill Taylor A.(PubMed)
(201) Non-pharmacological interventions for fatigue in rheumatoid arthritis by Cramp F1, Hewlett S, Almeida C, Kirwan JR, Choy EH, Chalder T, Pollock J, Christensen R.(PubMed)
(202) Anti-inflammatory activity of the topical preparation of Valeriana wallichii and Achyranthes aspera leaves by Khuda F1, Iqbal Z, Khan A, Zakiullah, Nasir F, Shah Y.(PubMed)
(203) Antimicrobial and anti-inflammatory activities of leaf extract of Valeriana wallichii DC by Khuda F1, Iqbal Z, Zakiullah, Khan A, Nasir F.(PubMed)

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Individual herbs - Comfrey

         Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                     

                  Polymyalagia Arthritis (Rheumatica)



Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.           
   Treatments
          
B.2. Herbal and Traditional Chinese medicine 
Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including 
B.2.1. Individual herb
1. Comfrey 
Comfrey is a perennial Plant in the genus of Symphytum, belongings to the family Boraginaceae, native to Europe,  used in herbal and traditional medicine to ease excessive bleeding or on open wounds, relief pain and swollen, treat circulation issues, reduce cholesterol, etc. According to Merck Selbstmedikation GmbH, in the searching of the literature of multiple randomized controlled trials suggested that topical comfrey treatment significantly reduce pain, inflammation and swelling of muscles and joints in degenerative arthritis, acute myalgia in the back, sprains, contusions and strains after sports injuries and accidents, also in children aged 3 or 4 and over(194)
Dr. Staiger C said, "Comfrey root extract has been used for the topical treatment of painful muscle and joint complaints. It is clinically proven to relieve pain, inflammation and swelling of muscles and joints in the case of degenerative arthritis, acute myalgia in the back, sprains"(195).
Furthermore, the Universidade Federal dos Vales do Jequitinhonha e Mucur study in the investigation of the efficacy of comfrey expressed the promising result in control the inflammatory process and to induce collagen deposition at 8% concentration(196).

(194) Comfrey: a clinical overview by Staiger C1.(PubMed)
(195) Comfrey root: from tradition to modern clinical trials by Staiger C1.(PubMed)
(196) In vivo wound healing effects of Symphytum officinale L. leaves extract in different topical formulations by Araújo LU1, Reis PG, Barbosa LC, Saúde-Guimarães DA, Grabe-Guimarães A, Mosqueira VC, Carneiro CM, Silva-Barcellos NM.(PubMed)



                               

                              

                               
                          

Monday, 28 March 2016

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Individual herbs - Devil's claw

     Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                     

                  Polymyalagia Arthritis (Rheumatica)



Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.      

                          Treatments

B.2. Herbal and Traditional Chinese medicine 
Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including 
B.2.1. Individual herb
2. Devil's claw
Devil's claw also known as wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa.The plant has been used as herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidneys conditions, etc. Because of its strongly anti inflammatory activities, the herb may be used to treat inflammatory rheumatic disease, causing pain, stiffness and tenderness in large muscles. According to University Hospital Zurich, Extracts of devil's claw inhibited a wide range of proinflammatory mediators(199) which are important in the pathophysiology of inflammatory rheumatic disease(197).
Dr. Chrubasik S said that preparations of devil's claw extract, should be taken account of the presence of the quantity of harpagoside of which has proven importantly in relived painful lower back or arthrotic pain as an attractive alternative to synthetic analgesics(198).

(197) Alteration of anti-inflammatory activity of Harpagophytum procumbens (devil's claw) extract after external metabolic activation with S9 mix by Hostanska K1, Melzer J, Rostock M, Suter A, Saller R.(PubMed)
(198) [Devil's claw extract as an example of the effectiveness of herbal analgesics].[Article in German] by Chrubasik S1.(PubMed)
(199) Inhibitory effects of devil's claw (secondary root of Harpagophytum procumbens) extract and harpagoside on cytokine production in mouse macrophages by Inaba K1, Murata K, Naruto S, Matsuda H.(PubMed)




                   

Sunday, 27 March 2016

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Preventive Minerals and Vitamins

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                     

                  Polymyalagia Arthritis (Rheumatica)


Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

                                                        Treatments

B. In herbal  and traditional Chinese medicine perspective
B.3. The Preventive Minerals and Vitamins
Certain minerals and vitamin such as  magnesium, selenium, copper and vitamin D may be a good sources of pain reliever according to the studies(325,180). According to the randomized to four double-blinded treatments for 12 weeks by Minnesota Applied Research Center, Glucosamine sulfate (1500 mg/d), Aquamin (2400 mg/d) and Combined treatment composed of Glucosamine sulfate (1500 mg/d) have shown effectively in improvements in symptoms of pain and stiffness of osteoarthritis(315,181).
1. Magnesium
Magnesium sulfate has shown to relieve pain in patients undergoing laparoscopic cholecystectomy (LC)(182) and neuropathic pain(183).
According to Dr. Sun J and the research team lead by the Wenzhou Medical University, magnesium used alone or conjunction with ropivacaine are effectively in exhibition of postoperative analgesia in children(184).
In fact, patient with chronic inflammatory diseases are found to associate to magnesium depletion. Dr. Nielsen FH. said," Magnesium deficiency should be considered a nutrient of significant concern for health and well-being"(185).

2. Selenium
Selenium therapy have shown to associate to pain reduction, according to study by Fourth Military Medical University(186).
In chronic pancreatitis, according to the systematic review and meta-analysis was performed per PRISMA guidelines, organic selenium may be effective for treatment of chronic pain as the result of reported change in pain score(187).
According to the Universidad de Buenos Aires, patient with chronic inflammatory diseases are found to have low levels of selenium serum(188).

3. Copper
Used topical Copper-salicylate gel has shown to relief pain for patients with the hip or knee osteoarthritis with side effects of skin rashes(330,189).
Other topical Cu-Indo gel has shown effectively against joint inflammation in the MIA-treated rat model of osteoarthritis(332,190). 
Deficiency of copper is found to associate with inflammation, oxidative Stress, and metabolic variables in adults, according to the 2008 American Society for Nutrition publication(191).

4. Vitamin D
According to the study by the University of Alberta, vitamin D may have beneficial effects in specific chronic painful conditions(192)and Vitamin D deficiency has recently been linked with a range of diseases including chronic pain(193).

All Forms of Arthritis are Curable

Ovarian Cysts And PCOS Elimination


References
(156) Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans by Bjarnason I1, Hayllar J, MacPherson AJ, Russell AS.(PubMed)
(157) Adverse outcomes of antiinflammatory therapy among patients with polymyalgia rheumatica by Gabriel SE1, Sunku J, Salvarani C, O'Fallon WM, Hunder GG.(PubMed)
(325,180) Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritis and osteoarthritis by Yazar M1, Sarban S, Kocyigit A, Isikan UE.(PubMed)
(325,181) Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritis and osteoarthritis by Yazar M1, Sarban S, Kocyigit A, Isikan UE.(PubMed)
(182) Effect of intraoperative magnesium sulphate infusion on pain relief after laparoscopic cholecystectomy by Mentes O1, Harlak A, Yigit T, Balkan A, Balkan M, Cosar A, Savaser A, Kozak O, Tufan T.(PubMed)
(183) [Relief of neuropathic pain with intravenous magnesium].[Article in Japanese] by Tanaka M1, Shimizu S, Nishimura W, Mine O, Akatsuka M, Inamori K, Mori H.(PubMed)
(184) Pre-emptive peritonsillar infiltration of magnesium sulphate and ropivacaine vs. ropivacaine or magnesium alone for relief of post-adenotonsillectomy pain in children by Sun J1, Wu X2, Zhao X1, Chen F1, Wang W3.(PubMed)
(185) Effects of magnesium depletion on inflammation in chronic disease by Nielsen FH1.(PubMed)
(186) Antioxidant therapy for pain relief in patients with chronic pancreatitis: systematic review and meta-analysis by Cai GH1, Huang J, Zhao Y, Chen J, Wu HH, Dong YL, Smith HS, Li YQ, Wang W, Wu SX.(PubMed)
(187) Role of methionine containing antioxidant combination in the management of pain in chronic pancreatitis: a systematic review and meta-analysis by Talukdar R1, Murthy HV2, Reddy DN3.(PubMed)
(188) Host selenium deficiency increases the severity of chronic inflammatory myopathy in Trypanosoma cruzi-inoculated mice by Gomez RM1, Solana ME, Levander OA.(PubMed)
(330,189) Copper-salicylate gel for pain relief in osteoarthritis: a randomised controlled trial.Shackel NA1, Day RO, Kellett B, Brooks PM.(PubMed)
(332, 190) Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis by Yassin NZ1, El-Shenawy SM1, Abdel-Rahman RF1, Yakoot M2, Hassan M3, Helmy S4.(PubMed)
(191) Associations of Dietary and Serum Copper with Inflammation, Oxidative Stress, and Metabolic Variables in Adults1,2 by Simona Bo3,*, Marilena Durazzo3, Roberto Gambino3, Carlo Berutti4,
Nadia Milanesio3, Antonio Caropreso4, Luigi Gentile5, Maurizio Cassader3,Paolo Cavallo-Perin3, and  Gianfranco Pagano3(The journal of nutrition)
(192) Vitamin D for the treatment of chronic painful conditions in adults by Straube S1, Derry S, Moore RA, McQuay HJ.(PubMed)
(193) Vitamin D Deficiency Linked to Depression, Pain, Inflammatory Bowel Disease, and Breast Cancer by Dr. Mercola

                   

Saturday, 26 March 2016

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Nuts and seeds Olive

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                     

                  Polymyalagia Arthritis (Rheumatica)


Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

                                Treatments
 
B. In herbal  and traditional Chinese medicine perspective
3. Nuts and seeds Olive
Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil.

Olive Oil: Fat Content
1. Saturated fats
a. Palmitic acid
b. Stearic acid
c. Arachidic acid
d. ehenic acid
e. Myristic acid
f. Lignoceric acid
2. Unsaturated fat3. Monounsaturated fats
a. Oleic acid
b. Palmitoleic acid
3. Polyunsaturated fats
a. Linoleic acid
b. Linolenic acid

Monounsaturated fatty acids found abundantly in olive oil, may be beneficiary for reduced inflammation and induced antioxidation(362,175).
In a pilot double-blinded, randomized, clinical trial of topical virgin olive oil versus piroxicam gel in osteoarthritis of the knee, conducted by Ardabil University of Medical Science, researchers showed use of  olive oil in the experiment is more effective than medical gel for knee osteoarthritis, probably due to its phytochemiocals oleuropein and hydroxy tyroso(364,176).
Its omega-3 fatty acids component is also found to attenuate several inflammatory and degenerative diseases, through the expression of anti-inflammatory and immunomodulatory properties(177) of that may be potential effect for treatment of PMR, a low chronic inflammatory disease.
In chronic pain diseases, omega 3 fatty acids also exhibited anti analgesic property when it used either alone or in combination with morphine after acute and chronic administration in rats(178).
Dr. Ramsden CE and the research team lead by the National Institutes of Health suggested, with the biosynthetic precursors of endocannabinoids with antinociceptive, anxiolytic, and neurogenic, omega 3 fatty acids, could have physical and/or psychological pain modulating properties(179).

All Forms of Arthritis are Curable

Ovarian Cysts And PCOS Elimination

References
(156) Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans by Bjarnason I1, Hayllar J, MacPherson AJ, Russell AS.(PubMed)
(157) Adverse outcomes of antiinflammatory therapy among patients with polymyalgia rheumatica by Gabriel SE1, Sunku J, Salvarani C, O'Fallon WM, Hunder GG.(PubMed)
(362,175) Extra-virgin olive oil diet and mild physical activity prevent cartilage degeneration in an osteoarthritis model: an in vivo and in vitro study on lubricin expression by Musumeci G, Trovato FM, Pichler K, Weinberg AM, Loreto C, Castrogiovanni P.(PubMed)
(364,176) A pilot double-blinded, randomized, clinical trial of topical virgin olive oil versus piroxicam gel in osteoarthritis of the knee.in Bohlooli S1, Jastan M, Nakhostin-Roohi B, Mohammadi S, Baghaei Z.(PubMed)
(177) An update on the role of omega-3 fatty acids on inflammatory and degenerative diseases by Lorente-Cebrián S1, Costa AG, Navas-Carretero S, Zabala M, Laiglesia LM, Martínez JA, Moreno-Aliaga MJ.(PubMed)
(178) Analgesia enhancement and prevention of tolerance to morphine: beneficial effects of combined therapy withomega-3 fatty acids by Escudero GE1, Romañuk CB2, Toledo ME1, Olivera ME2, Manzo RH2, Laino CH1.(PubMed)
(179) Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress by Ramsden CE1, Zamora D2, Makriyannis A3, Wood JT3, Mann JD4, Faurot KR2, MacIntosh BA5, Majchrzak-Hong SF6, Gross JR7, Courville AB8, Davis JM9,Hibbeln JR6.(PubMed)



Friday, 25 March 2016

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Salmon Calcitonin

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                     

                  Polymyalagia Arthritis (Rheumatica)


Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

                           Treatments
 
B. In herbal  and traditional Chinese medicine perspective
2. Cold water fish Salmon
Salmon is the common name for Salmonidae. They are anadromous, born in fresh water, migrate to the ocean, then travel thousands of miles in the deep sea cold water throughout their life cycle and within to five years returning to the exacted location where they were born to reproduce and die.

Nutrients
1. Protein
2. Omega-3 fatty acids
3. B vitamins
4. Vitamin D
5. Astaxanthin
is a potent antioxidant that stimulates the development of healthy fish nervous systems and enhances the fish's fertility and growth rate.
6. Selenium
7. Tryptophan
8. Magnesium
9. Phosphorus
10. Etc.

Use of salmon calcitonin, a hormone produced by the thyroid gland of salmon or a synthetic polypeptide of the same sequence found in salmon(360, 170) has shown to reduce PMR complications. Dr. Ryan SM and the research team at the Dublin Institute of Technology, suggested that salmon calcitonin may also portent for treatment of inflammatory arthritis through activation of the DNA expression of  of steroid-thyroid hormone-retinoid receptor and  tissue remodeling and degradation of the extracellular matrix (ECM) of  collagens, elastins, gelatin, matrix glycoproteins, and proteoglycan(172).
A randomized controlled trial of salmon calcitonin attenuate bone loss in corticosteroid-treated temporal arteritis and polymyalgia rheumatica patients by reducing the incidence of vertebral fracture of 12.5%, with four fractures in the first year and one fracture in the subsequent year(171).
In Fact, salmon calcitonin has also been used to reduce pain in patient with inflammatory arthritis diseases, including patient with osteoporotic vertebral crush fractures(173) and spinal pain(174).. through its analgesic effect , a prospective double-blind, randomized, placebo-controlled clinical study insisted

(362,170)
(171) A randomized controlled trial of salmon calcitonin to prevent bone loss in corticosteroid-treated temporal arteritis and polymyalgia rheumatica by Healey JH1, Paget SA, Williams-Russo P, Szatrowski TP, Schneider R, Spiera H, Mitnick H, Ales K, Schwartzberg P.(PubMed)
(172) An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis by Ryan SM1, McMorrow J, Umerska A, Patel HB, Kornerup KN, Tajber L, Murphy EP, Perretti M, Corrigan OI, Brayden DJ.(PubMed)
(173) Pain relief from nasal salmon calcitonin in osteoporotic vertebral crush fractures. A double blind, placebo-controlled clinical study by Lyritis GP1, Paspati I, Karachalios T, Ioakimidis D, Skarantavos G, Lyritis PG.(PubMed)
(174) Analgesic effect of salmon calcitonin suppositories in patients with acute pain due to recent osteoporotic vertebral crush fractures: a prospective double-blind, randomized, placebo-controlled clinical study by Lyritis GP1, Ioannidis GV, Karachalios T, Roidis N, Kataxaki E, Papaioannou N,
Kaloudis J, Galanos A.(PubMed)

   

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): Top foods to reduce risk of inflammation

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                     

                  Polymyalagia Arthritis (Rheumatica)


Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

                                             Treatments

B. In herbal  and traditional Chinese medicine perspective
B.1. Diet modification according herbal and TCM medicine specialist
1. Top foods to reduce risk of inflammation
Low-grade inflammation has found to play a pathophysiological role in patient with Polymyalgia Rheumatica(PMR), according to the University Giessen(158).According to Medical University Innsbruck, the relationship between diet, immunity, and the microbiota, may be necessary for us to rethink of the develop diet-based approaches to prevent or treat many diseases(283,159).
1. 1.Garlic
Garlic (Allium sativum) is a species in the onion genus, belongings to family Amaryllidaceae, native to central Asia, used popularly in traditional and Chinese medicine to treat common cold and flu, strengthen immunity, etc.... Recent studies also showed that garlic exhibits its anti-inflammatory effects against chronic inflammatory disease(160) through regulation of production of NO and pro-inflammatory cytokines and other mechanisms(161).

1.2. Ginger
Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil, used in traditional and Chinese medicine to treat rheumatoid arthritis and osteoarthritis. Recent study showed that ginger expressed its anti inflammatory effects through its mediators within the complexity of antioxidant activity(162).
According to the joint study of the Tshwane University of Technology, ginger's phytochemicals beside expressed its effects on anti-inflammation, it also exhibited a host of biological activities, ranging from anticancer, anti-oxidant, antimicrobial, and anti-allergic to various central nervous system activities(163).

1.3. Turmeric
Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia. The herb has been used in traditional medicine as anti-oxidant, anti inflammations, etc. agent. Epidemiological studies also found that the efficacy of turmeric for treatment for low grade inflammatory diseases(164) through its anti inflammatory(165), antioxidant(165) and immunmodulatory activities.

1.4. Green tea
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, green tea has been cultivated for commercial purposes all over the world. Epidemiological studies suggested that green tea improved chronic inflammatory diseases through its anti proinflammatory cytokines(166) and
 its antioxidant(168), anti inflammatory(167) and immune modulatory(169) activities.

(158) Ultrasonography of the glenohumeral joints--a helpful instrument in differentiation in elderly onset rheumatoid arthritis and polymyalgia rheumatica by Lange U1, Piegsa M, Teichmann J, Neeck G.(PubMed)
(283,159) Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease by Kirsty Brown,† Daniella DeCoffe,† Erin Molcan, and Deanna L. Gibson(PubMed)
(160) Short-term heating reduces the anti-inflammatory effects of fresh raw garlic extracts on the LPS-induced production of NO and pro-inflammatory cytokines by downregulating allicin activity in RAW 264.7 macrophages. by Shin JH1, Ryu JH, Kang MJ, Hwang CR, Han J, Kang D.(PubMed)
(161) aged black garlic exerts anti-inflammatory effects by decreasing no and proinflammatory cytokine production with less cytoxicity in LPS-stimulated raw 264.7 macrophages and LPS-induced septicemia mice. by Kim MJ1, Yoo YC, Kim HJ, Shin SK, Sohn EJ, Min AY, Sung NY, Kim MR.(PubMed)
(162) Evaluation of in vitro anti-inflammatory effects of crude ginger and rosemary extracts obtained through supercritical CO2 extraction on macrophage and tumor cell line: the influence of vehicle type. by Justo OR1, Simioni PU2, Gabriel DL2, Tamashiro WM2, Rosa Pde T3, Moraes ÂM4.(PubMed)
(163) Gingerols and shogaols: Important nutraceutical principles from ginger by Semwal RB1, Semwal DK1, Combrinck S2, Viljoen AM3.(PubMed)
(164) Effect of citrus polyphenol- and curcumin-supplemented diet on inflammatory state in obese cats by Leray V1, Freuchet B, Le Bloc'h J, Jeusette I, Torre C, Nguyen P.(PubMed)
(165) Anti-inflammatory and anti-oxidant properties of Curcuma longa (turmeric) versus Zingiber officinale (ginger) rhizomes in rat adjuvant-induced arthritis by Ramadan G1, Al-Kahtani MA, El-Sayed WM.(PubMed)
(166) Green tea polyphenol epigallocatechin-3-gallate and cranberry proanthocyanidins act in synergy with cathelicidin (LL-37) to reduce the LPS-induced inflammatory response in a three-dimensional co-culture model of gingival epithelial cells and fibroblasts by Lombardo Bedran TB1, Palomari Spolidorio D2, Grenier D3.(PubMed)
(167) Antiinflammatory action of EGCG, the main component of green tea, through STAT-1 inhibition by Tedeschi E1, Suzuki H, Menegazzi M.(PubMed)
(168) Antioxidant potential of green and black tea determined using the ferric reducing power (FRAP) assay by Langley-Evans SC1.(PubMed)
(169) Green Tea Epigallocatechin-3-Gallate Suppresses Autoimmune Arthritis Through Indoleamine-2,3-Dioxygenase Expressing Dendritic Cells and the Nuclear Factor, Erythroid 2-Like 2 Antioxidant Pathway by Min SY1, Yan M1, Kim SB2, Ravikumar S3, Kwon SR4, Vanarsa K3, Kim HY5, Davis LS1, Mohan C3(PubMed)