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By Kyle J. Norton Health article writer and researcher; Over 10.000
articles and research papers have been written and published on line,
including world wide health, ezine articles, article base, healthblogs,
selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by
Disilgold.com Named 50 of the best health Tweeters Canada - Huffington
Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as
international journal Pharma and Bio science, ISSN 0975-6299.
What is Candida Albicans
Candida
albican is a member of a large group of micro organisms whose cells contain
complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and
mold(6) that live among the gut flora in the human mouth and
gastrointestinal tract. In fact, under normal circumstances, Candida
albicans that does not cause harmful effects, but overgrowth results in
candidiasis. Non-
albicans Candida
(NAC) species cause 35-65% of all candidaemias in the general patient
population(1). According to joint study, in many cases, biofilm(
microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and overexpression of genes(9)(10) are often associated with increased
Candida resistance toward antifungal agents.
Symptoms of Candidiasis
Depending to types and places of infection, you may experience some of the below symptoms.
1. Salivary
changes included low hydration level, high saliva viscosity,
below-average pH, reduced salivary flow and low saliva buffer capacity,
according to "Carol Davila" University of Medicine and Pharmacy(20).
2. Persistence drowsiness
3. Lack of coordination
4. Headaches
5. Mood swing
6. Loss of balance
7. Rashes
8. Mucus in stool
9. Betching and wind
10. Bad breath
11. Dry mouth
12. Postnasal drop
13. Nasal itch and/or congestion
14. Nervous irritability
15. Dry mouth or throat
16. Ear sensitive or fluid in ear
17. Heartburn and indigestion
18. Symptoms worse in damp day
19. Etc.
Risk Factors of Candidiasis
1. Age
Human
aging is a biological process. As we age, our immune system is no
longer function properly(24)(25) in regulating the balance of
microorganisms in
the body(22) due to free radicals accumulated(23) over the year.
Through weakening the toll-like receptors which plays an important role
in the innate immune system. and natural killer cell may induce the
onset or progression of
candidiasis(21).
2. Chronic illness
Chronic
illness, such as immunodeficiency(29), chronic liver
diseases(30), diabetes(31)(32)(34), obesity(33)(34) weakens the defense
system in
regulating the microorganism(26)(27) in the digestive track, leading to
over
growth of candida(28).
3. Use of catheters(34)
Catheters is a
tube
that can be inserted into a body cavity, duct, or vessel allowing
drainage, administration of fluids or gases, or access by surgical
instruments. Use of catheter might sometime provides the candida(35)(36)with a
deeper, easy for organisms to get to site foe easy multiplying
4. Inhalant medicine
Repeated
use of the steroid inhalant such as residual inhaled corticosteroids
(ICSs) on the oral mucosa can result in the development of fungal
overgrowth(37)(38) induced candidiasis(39).
5. Radiotherapy
Candidiasis
is also seen in people who have undergone radiotherapy treatment for
cancer or as a side effect of certain types of medication(40)(41)(42).
6. Low level of stomach acids
Low
level of stomach acids increase the presence of undigested food in
the small intestine and colon, causing an overgrowth of harmful
bacteria and microorganism, leading to candida(43)(44).
7. Pregnancy
Studies
have shown that pregnant women are more susceptible to candida
infections(45)(46) than any other time in their lives, due to weakened
immune system and changes in hormonal status(47), especially in the
second trimester(48).
8. Use of contraceptive pill or hormone replacement therapy
Use
of contraceptive pill(49)(50) or hormone replacement therapy(53)(54) promotes the surge
in hormones in contributing over growth of candida, resulting in
unpleasant symptoms that come along with it.
9.
Drug used for controlling intestinal flora
Antibiotic
drugs induced
antibiotic-induced changes in the bacterial microbiome may lead to C. albicans colonization(55)and exhibit severely impairing
digestion(56)(57) and assimilation of nutrients(58) induced fatigue,
aggression, depression and toxicity.
9. Women who have sex with women
According to Department of Primary Care and Population Sciences, University College, the odds of
candidiasis are proportionally associated to with sexual activity between women(51)
as bacterial vaginosis (BV) may be sexually transmitted between women(52).
10. Etc.
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References
(1) Non-
albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance by Krcmery V
1, Barnes AJ.(
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(3) Multidrug resistance in
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1, Kapoor K.(
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(5) Mechanisms of resistance to azole antifungal agents in
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(6) Structural analysis of phospho-D-mannan-protein complexes isolated from yeast and
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5, Mahmoud AZ
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Age-related alteration of expression and function of TLRs and NK activity in oral
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Enzymatic dysfunction of mitochondrial complex I of the Candida
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(24) The role of nutrition in enhancing
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(25) As we age: Does slippage of quality control in the immune system lead to collateral damage? by Müller L
1, Pawelec G
2.(
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(26)The
prevalence of neonatal herpes simplex virus infection compared with
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, Almendarez Y
, Selwyn BJ.(
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(27) Rhinovirus
infection associated with
serious illness among pediatric patients by McMillan JA
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(29) Autoimmune polyendocrinopathy
candidiasis ectodermal dystrophy and other primary immunodeficiency
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chronic mucocutaneous
candidiasis by Kisand K
1, Peterson P.(
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(30)
Candidiasis and other oral mucosal lesions during and after interferon therapy for HCV-related
chronic liver
diseases by Nagao Y
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candidiasis in patients with
diabetes mellitus: a thorough analysis by Bartholomew GA
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1, Padshetty NS, Bai KY, Rao MS.(
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candidiasis in the absence of clinically overt oral involvement: a cross-sectional study by Glavey SV
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Once-daily fluticasone furoate is efficacious in patients with
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Cure zone
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pregnancy by Young GL
1, Jewell D.(P
ubMed)
(46) Treatment of vaginal
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(47)
Study results on the use of different therapies for the treatment of
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1, Stojic S.(
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1, Ronaci F, Torab R, Goldust M.(
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1, Foxman B, Gillespie BW.(
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