In the study to examine how changes in beverage consumption affect weight
change among adults, researchers at the Johns Hopkins Bloomberg School
of Public Health, showed that baseline mean intake of liquid calories
was 356 kcal/d (19% of total
energy intake). After potential confounders and intervention assignment
were controlled for, a reduction in liquid calorie intake of 100 kcal/d
was associated with a weight loss
of 0.25 kg (95% CI: 0.11, 0.39; P < 0.001) at 6 mo and of 0.24 kg
(95% CI: 0.06, 0.41; P = 0.008) at 18 mo. A reduction in liquid calorie
intake had a stronger effect than did a reduction in solid calorie
intake on weight loss. Of the individual beverages, only intake of sugar-sweetened beverages (SSBs) was significantly associated with weight change. A reduction in SSB intake of 1 serving/d was associated with a weight loss of 0.49 kg (95% CI: 0.11, 0.82; P = 0.006) at 6 mo and of 0.65 kg (95% CI: 0.22, 1.09; P = 0.003) at 18 mo(1).
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(1) "Reduction in consumption of sugar-sweetened beverages is associated with weight loss: the PREMIER trial" vy Chen L, Appel LJ, Loria C, Lin PH, Champagne CM, Elmer PJ, Ard JD, Mitchell D, Batch BC, Svetkey LP, Caballero B.
Tuesday, 31 December 2013
Replacing caloric beverages with water or diet beverages for weight loss
In the study to compare the replacement of caloric beverages with water or diet beverages (DBs) as a method of weight loss over 6 mo in adults and attention controls (ACs), researchers at the The University of North Carolina at Chapel Hill, showed that Replacement of caloric beverages with noncaloric beverages as a weight-loss strategy resulted in average weight losses of 2% to 2.5%. This strategy could have public health significance and is a simple, straightforward message. This trial was registered at clinicaltrials.gov as NCT01017783(1).
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(1) " Replacing caloric beverages with water or diet beverages for weight loss in adults: main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial" by Tate DF, Turner-McGrievy G, Lyons E, Stevens J, Erickson K, Polzien K, Diamond M, Wang X, Popkin B.
Dietary intervention and vasomotor symptoms
In the study to determine whether a dietary intervention designed to reduce fat
intake and increase intake of fruit, vegetables, and whole grains, and weight loss, reduces vasomotor symptoms (VMS; ie, hot flashes or night sweats) in postmenopausal women, research indicated in multivariate-adjusted analyses, with simultaneous adjustment for the intervention and weight
change, assignment to the dietary intervention versus the control arm
was significantly (odds ratio [OR], 1.14; 95% CI, 1.01-1.28) related to a
higher likelihood of symptom elimination among women with VMS at baseline. In addition, women with symptoms at baseline who lost 10 lb or more (OR, 1.23; 95% CI, 1.05-1.46) or lost 10% or more of their baseline body weight
(OR, 1.56; 95% CI, 1.21-2.02) between baseline and year 1 were
significantly more likely to eliminate VMS compared with those who
maintained weight. Upon examining the joint effect of the dietary modification and weight loss, compared with women in the control arm who maintained weight, women who lost substantial weight
(≥10%) as a part of the intervention (OR, 1.89; 95% CI, 1.39-2.57) but
not as part of the control arm (OR, 1.40; 95% CI, 0.92-2.13) were
significantly more likely to end VMS, although these two groups did not
differ significantly from each other. Large weight loss (>22 lb), but not dietary changes, was related to the elimination of moderate/severe VMS(1).
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(1) "Effects of a dietary intervention and weight change on vasomotor symptoms in the Women's Health Initiative|" by Kroenke CH, Caan BJ, Stefanick ML, Anderson G, Brzyski R, Johnson KC, Leblanc E, Lee C, La Croix AZ, Park HL, Sims ST, Vitolins M, Wallace R.
Chinese Secrets To Fatty Liver And Obesity Reversal
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(1) "Effects of a dietary intervention and weight change on vasomotor symptoms in the Women's Health Initiative|" by Kroenke CH, Caan BJ, Stefanick ML, Anderson G, Brzyski R, Johnson KC, Leblanc E, Lee C, La Croix AZ, Park HL, Sims ST, Vitolins M, Wallace R.
Alternative Medicine for Weight Loss Among Mexican-American Women
In the study to examine the use of complementary and alternative medicine (CAM) for weight loss among Mexican-American women. Cross-sectional survey of different CAM modalities, including traditional Mexican medicine therapies, showed that most respondents reported using some form of CAM for weight loss, with most reporting using herbs and teas (70 %), home remedies (61 %) and massage (55 %). Mexican-American women report using a wide range of CAM therapies for weight loss. Understanding their patterns of use will enhance cultural competence of health care professionals and help address their medical needs(1).
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(1) "Use of Alternative Medicine for Weight Loss Among Mexican-American Women" by Lindberg NM, Stevens VJ, Elder C, Funk K, Debar L.
Monday, 30 December 2013
Herbal Cascara Sagrada (Rhamnus purshiana) and Metabolic syndrome or type 2 diabetes
Cascara sagrada is a species
of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native
to western North America, it's bark has been used in traditional
medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing, etc., effect.
Metabolic syndrome
According to the American Academy of Family Physicians, insulin resistance often goes along with other health problems, such as diabetes, high cholesterol and high blood pressure. These problems are all risk factors for heart disease. When a person has many of these problems at the same time, doctors commonly call it “metabolic syndrome.” It is sometimes called “insulin resistance syndrome” or “syndrome X.” Many people who have type 2 diabetes also have metabolic syndrome
Other defined it as a disorder of energy utilization and storage, diagnosed by a co-occurrence of 3 out of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density cholesterol (HDL) levels. The metabolic syndrome increases the risk of developing cardiovascular disease, particularly heart failure, and diabetes.
Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The ingredients
Beside the main compound of anthraquinones, other compounds include anthraquinone glycosides, (emodin, frangulin, iso-emodin, aloe-emodin, and chrysophanol), rhein, aloin, malic acid, tannic acid, cascarosides A, B, C, and D, hydroxy anthracene derivatives (HAD), etc.
The Benefits
Emodin, a chemical compound found in Cascara Sagrada may pocess the potential to treat matabolic syndrome by inhibiting 11beta-HSD1 activity of liver and fat significantly and reversing prednisone-induced insulin resistance in mice. Scientific evidence to support the above, including Dr. Wang and the research team in the study in ob/ob mice indicated that emodin (30 μmol/L) suppressed 11-dehydrocorticosterone-induced adipogenesis without affecting corticosterone-induced adipogenesis; emodin (3 μmol/L) reduced 11-dehydrocorticosterone-stimulated lipolysis, but had no effect on corticosterone-induced lipolysis. Moreover, emodin (3 μmol/L) partly reversed the impaired insulin-stimulated glucose uptake and adiponectin secretion induced by 11-dehydrocorticosterone but not those induced by corticosterone. In ob/ob mice, long-term emodin administration decreased 11β-HSD1 activity in mesenteric adipose tissues, lowered non-fasting and fasting blood glucose levels, and improved glucose tolerance. Other in the study of Glucocorticoid excess (Cushing's syndrome) causes metabolic syndrome showed that a selective 11β-HSD1 inhibitor, KR-67183, may provide a new therapeutic window in the prevention and treatment without toxicity in type 2 diabetes with obesity as KR-67183 concentration-dependently inhibited 11β-HSD1 activity in human and mouse 11β-HSD1 over-expressed cells and in the ex vivo assay of C57BL/6 mice and he administration of KR-67183 (20 and 50mg/kg/day, orally for 28 days) improved the glucose tolerance and insulin sensitivity with suppressed 11β-HSD1 activity in the liver and fat.
The Side effects
1. Cascara Sagrada can be liver toxic.
2. Postal hypertension
Cascara sagrada (CS) has been associated with the development of cholestatic hepatitis, complicated by portal hypertension.
3. Fresh cut, dried bark may cause vomiting and diarrhea.
4. It may cause allergic effect.
5. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
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Optimal Health And Loose Weight
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References
1. Metabolic syndrome (Wikipedia)
2. Metabolic syndrome, (American Academy of Family Physicians)
3. Cascara sagrada (Rhamnus purshiana)(Sigma Aldrich)
4. "Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice" by Feng Y, Huang SL, Dou W, Zhang S, Chen JH, Shen Y, Shen JH, Leng Y.(PubMed)
5. Emodin, an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, regulates adipocyte function in vitro and exerts anti-diabetic effect in ob/ob mice. by Wang YJ, Huang SL, Feng Y, Ning MM, Leng Y.(PubMed)
6. Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice. by Park JS, Rhee SD, Jung WH, Kang NS, Kim HY, Kang SK, Ahn JH, Kim KY.(PubMed)
7. [Toxic hepatitis following consumption of the herbal medicinal product Cascara Sagrada].[Article in Danish]" by Jacobsen C, Semb S, Kromann-Andersen H(PubMed)
8. "Cascara sagrada-induced intrahepatic cholestasis causing portal hypertension: case report and review of herbal hepatotoxicity" by Nadir A, Reddy D, Van Thiel DH.(PubMed)
9. "Occupational respiratory allergic disease induced by Passiflora alata and Rhamnus purshiana" by Giavina-Bianchi PF Jr, Castro FF, Machado ML, Duarte AJ.(PubMed)
Metabolic syndrome
According to the American Academy of Family Physicians, insulin resistance often goes along with other health problems, such as diabetes, high cholesterol and high blood pressure. These problems are all risk factors for heart disease. When a person has many of these problems at the same time, doctors commonly call it “metabolic syndrome.” It is sometimes called “insulin resistance syndrome” or “syndrome X.” Many people who have type 2 diabetes also have metabolic syndrome
Other defined it as a disorder of energy utilization and storage, diagnosed by a co-occurrence of 3 out of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density cholesterol (HDL) levels. The metabolic syndrome increases the risk of developing cardiovascular disease, particularly heart failure, and diabetes.
Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The ingredients
Beside the main compound of anthraquinones, other compounds include anthraquinone glycosides, (emodin, frangulin, iso-emodin, aloe-emodin, and chrysophanol), rhein, aloin, malic acid, tannic acid, cascarosides A, B, C, and D, hydroxy anthracene derivatives (HAD), etc.
The Benefits
Emodin, a chemical compound found in Cascara Sagrada may pocess the potential to treat matabolic syndrome by inhibiting 11beta-HSD1 activity of liver and fat significantly and reversing prednisone-induced insulin resistance in mice. Scientific evidence to support the above, including Dr. Wang and the research team in the study in ob/ob mice indicated that emodin (30 μmol/L) suppressed 11-dehydrocorticosterone-induced adipogenesis without affecting corticosterone-induced adipogenesis; emodin (3 μmol/L) reduced 11-dehydrocorticosterone-stimulated lipolysis, but had no effect on corticosterone-induced lipolysis. Moreover, emodin (3 μmol/L) partly reversed the impaired insulin-stimulated glucose uptake and adiponectin secretion induced by 11-dehydrocorticosterone but not those induced by corticosterone. In ob/ob mice, long-term emodin administration decreased 11β-HSD1 activity in mesenteric adipose tissues, lowered non-fasting and fasting blood glucose levels, and improved glucose tolerance. Other in the study of Glucocorticoid excess (Cushing's syndrome) causes metabolic syndrome showed that a selective 11β-HSD1 inhibitor, KR-67183, may provide a new therapeutic window in the prevention and treatment without toxicity in type 2 diabetes with obesity as KR-67183 concentration-dependently inhibited 11β-HSD1 activity in human and mouse 11β-HSD1 over-expressed cells and in the ex vivo assay of C57BL/6 mice and he administration of KR-67183 (20 and 50mg/kg/day, orally for 28 days) improved the glucose tolerance and insulin sensitivity with suppressed 11β-HSD1 activity in the liver and fat.
The Side effects
1. Cascara Sagrada can be liver toxic.
2. Postal hypertension
Cascara sagrada (CS) has been associated with the development of cholestatic hepatitis, complicated by portal hypertension.
3. Fresh cut, dried bark may cause vomiting and diarrhea.
4. It may cause allergic effect.
5. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Herbs http://kylejnorton.blogspot.ca/p/popular-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
1. Metabolic syndrome (Wikipedia)
2. Metabolic syndrome, (American Academy of Family Physicians)
3. Cascara sagrada (Rhamnus purshiana)(Sigma Aldrich)
4. "Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice" by Feng Y, Huang SL, Dou W, Zhang S, Chen JH, Shen Y, Shen JH, Leng Y.(PubMed)
5. Emodin, an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, regulates adipocyte function in vitro and exerts anti-diabetic effect in ob/ob mice. by Wang YJ, Huang SL, Feng Y, Ning MM, Leng Y.(PubMed)
6. Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice. by Park JS, Rhee SD, Jung WH, Kang NS, Kim HY, Kang SK, Ahn JH, Kim KY.(PubMed)
7. [Toxic hepatitis following consumption of the herbal medicinal product Cascara Sagrada].[Article in Danish]" by Jacobsen C, Semb S, Kromann-Andersen H(PubMed)
8. "Cascara sagrada-induced intrahepatic cholestasis causing portal hypertension: case report and review of herbal hepatotoxicity" by Nadir A, Reddy D, Van Thiel DH.(PubMed)
9. "Occupational respiratory allergic disease induced by Passiflora alata and Rhamnus purshiana" by Giavina-Bianchi PF Jr, Castro FF, Machado ML, Duarte AJ.(PubMed)
Herbal Butterbur and Migraine
Butterbur, found
in wet, marshy, damp land, including wetland, riverside, forest, etc.,
is a creeping underground plant, genus Petasites of 15 -20 species,
belonging to the family Asteraceae, native to Northern Hemisphere. It
has been used in herbal medicne used as an pain reliever in digestive
system, including stomach, bile ducts, and duodenum, etc.
Migraine headache is one most common headaches defined as condition of chronic neurological disorder of moderate to severe headaches, and nausea that usually develop gradually over 5–20 minutes and last for less than 60 minutes and affected over 15% of the population in US alone, as a result of the change in the brain and its surrounding blood vessels.
The Ingredients
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin and iso-S-petasin, etc.
The Benefits
Although the herb is used as nutritional supplement in US, scientific studies suggested that it may be used as the prevention of allergic rhinitis and treatment of migraine. In a three-arm, parallel-group, randomized trial comparing Petasites extract 75 mg bid, Petasites extract 50 mg bid, or placebo bid in 245 patients with migraine, Butterbur Petasites extract 75 mg bid is more effective than placebo and is well tolerated as a preventive therapy for migraine, with mild symptoms of gastrointestinal events, predominantly burping. Other study of extract of Petasites hybridus suggest that migraine patients can benefit from prophylactic treatment with this special extract. The combination of high efficacy and excellent tolerance emphasizes the particular value that Petasites hybridus has for the prophylactic treatment of migraine. But in a systematic review, the herbs is showed to have a Moderate evidence of effectiveness, thus, available for a higher than the recommended dose of the proprietary Petasites root extract Petadolex in the prophylaxis of migraine and suggested that rigorous studies are required to confirm effectiveness and safety in long-term use before treatment with Petasites root extract can be recommended the herb as an alternative option in the treatment to patient with the prophylaxis of migraine.
Side effects
1. Butterbur may be toxic to liver and cause cancer due to the presence of pyrrolizidine alkaloids
2. If you are pregnant please do not use Butterbur with out the permission of the related special field specialist
3. Allergic effect to certain people who are allergic to ragweed, marigold, daisy, etc.
4. Overdoses may cause indigestion, headache, nausea, vomiting, diarrhea, etc.
5. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Herbs http://kylejnorton.blogspot.ca/p/popular-herbs.html
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References
(1) Petasites hybridus root (butterbur) is an effective preventive treatment for migraine.
Migraine headache is one most common headaches defined as condition of chronic neurological disorder of moderate to severe headaches, and nausea that usually develop gradually over 5–20 minutes and last for less than 60 minutes and affected over 15% of the population in US alone, as a result of the change in the brain and its surrounding blood vessels.
The Ingredients
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin and iso-S-petasin, etc.
The Benefits
Although the herb is used as nutritional supplement in US, scientific studies suggested that it may be used as the prevention of allergic rhinitis and treatment of migraine. In a three-arm, parallel-group, randomized trial comparing Petasites extract 75 mg bid, Petasites extract 50 mg bid, or placebo bid in 245 patients with migraine, Butterbur Petasites extract 75 mg bid is more effective than placebo and is well tolerated as a preventive therapy for migraine, with mild symptoms of gastrointestinal events, predominantly burping. Other study of extract of Petasites hybridus suggest that migraine patients can benefit from prophylactic treatment with this special extract. The combination of high efficacy and excellent tolerance emphasizes the particular value that Petasites hybridus has for the prophylactic treatment of migraine. But in a systematic review, the herbs is showed to have a Moderate evidence of effectiveness, thus, available for a higher than the recommended dose of the proprietary Petasites root extract Petadolex in the prophylaxis of migraine and suggested that rigorous studies are required to confirm effectiveness and safety in long-term use before treatment with Petasites root extract can be recommended the herb as an alternative option in the treatment to patient with the prophylaxis of migraine.
Side effects
1. Butterbur may be toxic to liver and cause cancer due to the presence of pyrrolizidine alkaloids
2. If you are pregnant please do not use Butterbur with out the permission of the related special field specialist
3. Allergic effect to certain people who are allergic to ragweed, marigold, daisy, etc.
4. Overdoses may cause indigestion, headache, nausea, vomiting, diarrhea, etc.
5. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Herbs http://kylejnorton.blogspot.ca/p/popular-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Petasites hybridus root (butterbur) is an effective preventive treatment for migraine.
Lipton RB, Göbel H, Einhäupl KM, Wilks K, Mauskop A.(PubMed)
(2) An extract of Petasites hybridus is effective in the prophylaxis of migraine.
Grossman W, Schmidramsl H.(PubMed)
(3) Effectiveness of Petasites hybridus preparations in the prophylaxis of migraine: a systematic review.
Agosti R, Duke RK, Chrubasik JE, Chrubasik S.(PubMed)
(4) Simultaneous investigation of sesquiterpenes, pyrrolizidine alkaloids and N-oxides in Butterbur (Petasites hybridus) with an offline 2D-combination of HPLC-UV and LC-MMI-ToF-MS.
Aydın AA, Letzel T.(PubMed)
Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes
Consumption of sugar-sweetened beverages (SSBs), which include soft
drinks, fruit drinks, iced tea, and energy and vitamin water drinks has
risen across the globe. Regular consumption of SSBs has been associated
with weight gain and risk of overweight
and obesity, but the role of SSBs in the development of related chronic
metabolic diseases. Researchers at the Harvard School of Public Health
found that in addition to weight
gain, higher consumption of SSBs is associated with development of
metabolic syndrome and type 2 diabetes. These data provide empirical
evidence that intake of SSBs should be limited to reduce obesity-related
risk of chronic metabolic diseases(1).
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Obesity http://kylejnorton.blogspot.ca/p/obesitys-complications.htmlt
(1) "Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis" by Malik VS, Popkin BM, Bray GA, Després JP, Willett WC, Hu FB.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Obesity http://kylejnorton.blogspot.ca/p/obesitys-complications.htmlt
(1) "Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis" by Malik VS, Popkin BM, Bray GA, Després JP, Willett WC, Hu FB.
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