Saturday 10 June 2023

#Healthyfood #DriedPeas In the Inhibition of #Hyperlipidemia in Clinical Trials

By Kyle J. Norton

Epidemiological studies suggested that the intake of dried peas fiber daily and regularly may significantly affect the reduced risk of hyperlipidemia.

Dried peas are a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae processed healthy source of proteins, fibers, vitamins, and minerals.

Hyperlipidemia is a condition characterized by high levels of cholesterol in the bloodstream.

In a study of 173 women and men, with a mean body mass index of approximately 36 kg m(-2) (one-fifth with diabetes type 2) randomized assigned to a high-fiber fiber bean-rich diet that achieved mean (SD) fiber intakes of 35.5 (18.6) g day for women and 42.5 (30.3) g day for men or a low-carbohydrate diet, researchers found that
1. High bean fiber intake showed better weight loss and weight control compared to the low carbohydrate diet group.
2. Intake of bean fiber group expressed a significant decrease of Low-density lipoprotein (LDL)-cholesterol and total cholesterol levels, compared to another group.

Dr. Tonstad S, the lead author said, "A high-fiber bean-rich diet was as effective as a low-carbohydrate diet for weight loss, although only the bean-rich diet lowered atherogenic lipids".

Additionally, in dyslipidemia rats study to evaluate the effects of the grain-bean package, dietary fiber (DF) extracted from the grain-bean package, and DF from grain corn on the blood lipids and fatty acid synthase (FAS) activity in high-fat, high-cholesterol feeding by randomly assigned into normal control group, hyperlipidemia model group, grain-bean package group, grain-bean package DF group, and grain corn group, researchers after adjusting to other risk factors filed the following results
1. Rats in the hyperlipidemic model group showed increased total cholesterol (TC), triglyceridaemia (TG), high-density lipoprotein cholesterol (HDL-C), and fasting blood glucose (FBG), compared to groups.

2. Compared to the hyperlipidemic model group, the grain-bean package group, and grain-bean package DF group, expressed significantly decreased total cholesterol (TC), triglyceridaemia (TG), high-density lipoprotein cholesterol (HDL-C), fasting blood glucose, and significantly increased HDL-C levels.

These findings demonstrated that dietary fiber can improve blood lipids levels in dyslipidemic subjects, decrease FAS activity and regulate SREBP-1c mRNA in glucose metabolic expression.

Dr. Ullrich IH. in the review literature of a high-fiber diet in hyperlipidemia suggested that fiber from sources such as bean and karaya have a strong effect in decreased total cholesterol due primarily to a decrease in the low-density lipoprotein cholesterol fraction and adding large amounts of sucrose into fiber may offer some protection against an increase in cholesterol and triglyceride levels as both normal and elevated triglyceride levels appear to be more resistant to change with dietary fiber.

Taking it together, just like other bean fibers, intake of dried bean fiber may have a profound effect in reduced risk and treatment of hyperlipidemia, one of the major causes of heart disease and stroke.


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Sources
(1) A high-fiber bean-rich diet versus a low-carbohydrate diet for obesity by Tonstad S1, Malik N, Haddad E.(PubMed)
(2) [Effect of the grain-bean package, grain-bean package dietary fiber, and single whole grain dietary fiber on dyslipidemia rats].[Article in Chinese] by Liu Y, Zhai C, Sun G, Zhang H, Jiang M, Zhang H, Guo J, Lan X.(PubMed)
(3) Evaluation of a high-fiber diet in hyperlipidemia: a review by Ullrich IH. (PubMed)

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