Tuesday 6 June 2023

#Healthyfood #Carrot Gobbles Up Pathogenic Microorganisms in Initiated Cell Infection, Scientists Reveal

By Kyle J. Norton

Carrots may have a profound and positive effect in gobbling up foreign microbial organisms before they can cause infection and damage to the host tissue, some scientists suggested.
The results of the veggie inhibition of micro-bacterial expression in an increased risk of infection were demonstrated by respectable institutes, including Iowa State University and Université de Monastir.

Infectious tissue caused by microbial organisms can induce transmissible disease or communicable diseases through the production of toxins.

The most common symptoms of infection are a fever. This is the result of the reaction of the immune response in stimulated overproduction of pro-inflammatory cytokines to protection the damage or injuries against micro pathogens.


However, over-repression of pro-inflammatory factors can also induce tissue damage and forming of scars.


Other common symptoms also include chills and sweats, cough, sore throat, nasal congestion,....and burning or pain with urination


Some researchers suggested that most people with a balance of antioxidants, produced by tissue enzymes and free radicals are normally performed quite well against microorganisms during the time of infection.

Unluckily, people with a weakened immune system caused by reduced levels of antioxidant enzymes may need to gobble up some anti-inflammatory agents to speed up their recovery.


Conventional antibiotics may be helpful, however, they can cause severe adverse effects.

Carrot, a root vegetable with orange color is a subspecies of Daucus carota, belongings to the family Apiaceae, native to Asia and Europe.

In the investigation the effect of essential oils extracted from Daucus carota L. (Apiaceae) seeds inhibited the spread of microbial organisms through comparison of 4 volatile compounds β-bisabolene (mean content of 39.33%), sabinene (8.53%), geranyl acetate (7.12%), and elemicin (6.26%), researchers found that application of all compounds exerts strong activity in inhibited expression of Gram-positive (Staphylococcus aureus) and two Gram-negative bacteria (Escherichia coli and Salmonella typhimurium).

The result of efficacy probably was due to carrot seed extract's protection of cell membrane against microorganisms in initiated cell infection

Normally, infectious agents invade the cell membrane as the entry point to alternate DNA of the healthy cells.

In vitro, injection of all major compounds also showed a potential effect against Candida albicans, a pathogenic yeast.

Furthermore, the essential oil of carrot seed extract also exerted a similar antibacterial and antifungal activity compared to the individual compound.

Some researchers suggested that antioxidants may also have a profound effect on the initiated expression of free radical cytotoxicity in facilitated damage and death of microorganisms, particularly in infectious cells.

Interestingly, the precipitated cytotoxicity induced by reactive oxygen species and carrot antioxidants did not cause harm to healthy cells.

Also, the expression of antioxidants in the found compound ameliorated the immune response to protect our body against the stimulation of microorganisms in initiated production of inflammatory cytokines without reduced immune activity.

Overexpression of proinflammation is not only associated with increased symptoms of swelling, pain, and fever but also increased risk of cell damage and apoptosis in the site of infection, leading to abnormal healing skin.

Additionally, in the analysis of the carrot essential oil from flowers and roots of Daucus carota L. ssp. Mauritius obtained by hydrodistillation, researchers at the Université de Monastir reported that out of thirty-two and six compounds were identified in flower and root oils, phenolic derivatives (76.3%), myristicin (31; 29.7%), and dillapiole (32; 46.6%) constituted to main fraction demonstrated most protective effect in the inhibition of a series of common human pathogenic bacteria.

According to the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) assays, the found chemical compound also inhibited some clinically and environmentally isolated strains.

The evidence suggested that carrots with abundant bioactive compounds may be used as a functional food for reduced risk and treatment of micro bacterial infection.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.


Sources
(1) Variation of the chemical composition and antimicrobial activity of the essential oils of natural populations of Tunisian Daucus carota L. (Apiaceae) by Rokbeni N1, M'rabet Y, Dziri S, Chaabane H, Jemli M, Fernandez X, Boulila A.(PubMed)
(2) Flower and root oils of the tunisian Daucus carota L. ssp. maritimus (Apiaceae): integrated analyses by GC, GC/MS, and 13C-NMR spectroscopy, and in vitro antibacterial activity by Jabrane A1, Jannet HB, Harzallah-Skhiri F, Mastouri M, Casanova J, Mighri Z.(PubMed)

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