Monday 30 December 2019

Cruciferous Vegetables Reduce the Risk of Atherosclerosis

By Kyle J. Norton

A cardiovascular disease is a group of conditions triggered by the abnormal function of the heart and blood vessels.

The 3 most common forms of cardiovascular disease in North America are coronary artery disease, peripheral artery disease, and carotid artery disease caused by plaques build-up of plaque in the arteries that supply blood to the heart, the arms and legs, and the brain.

Atherosclerosis is a medical condition caused by plaques accumulated on the wall of the arteries, leading to narrowing the arteries in transporting oxygenated blood to the heart and other parts of the body.

Atherosclerosis is a slow, progressive disease that may begin as early as childhood, caused by damage to the inner lining of the artery. However, the actual causes of the condition are debatable.

Depending on the blood obstruction, atherosclerosis can induce different types of heart disease and stroke.

Plaque is the make of cholesterols, calcium, and other toxic substances, including cadmium.

According to the statistics provided by Atherosclerosis Open Acess, 32% of deaths account for atherosclerosis, including  13.8% among adults of 20 years and above. In 2010, coronary heart disease mortality rate was about 60%.

Risk factors of atherosclerosis include high blood pressure and cholesterol, diabetes, being overweight or obese, an unhealthy diet, a family history of heart disease and physical inactivity, particularly smoking.

Some researchers suggested that since cholesterol makes up a big part in the plaque, an unhealthy diet with high saturated trans fat, red meat and processed meat may be the major cause of atherosclerosis.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding a potential remedy for the prevention of plaque accumulated on the arterial wall, researchers the effect of vegetable intake alone, and relationships to specific types of vegetables containing different phytochemical profiles on atherosclerosis.

According to the food-questionnaire returned by the participants, using the total vegetable intake calculated at baseline (1998),
* Women consuming ≥3 servings of vegetables each day had ≈4.6% to 5.0% lower mean common carotid artery IMT (CCA-IMT, P=0.014) and maximum CCA-IMT (P=0.004) compared with participants consuming <2 servings of vegetables.

* Furthermore, for each 10 g/d higher in cruciferous vegetable intake, there was an associated 0.006 mm (0.8%) lower mean CCA-IMT (P<0.01) and 0.007 mm (0.8%) lower maximum CCA-IMT (P<0.01).

* Some vegetable types showed no associated with CCA-IMT (P>0.05).

* Interesting, there were no associations observed between vegetables and plaque severity (P>0.05).

Based on the results, researchers said, "Increasing vegetables in the diet with a focus on consuming cruciferous vegetables may have benefits for the prevention of subclinical atherosclerosis in older adult women".
Taken altogether, cruciferous vegetables may be considered functional remedies for the prevention of atherosclerosis, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cruciferous and Total Vegetable Intakes Are Inversely Associated With Subclinical Atherosclerosis in Older Adult Women by Blekkenhorst LC1,2,3, Bondonno CP4,2, Lewis JR4,3,5,6, Woodman RJ7, Devine A4, Bondonno NP2, Lim WH8, Zhu K9, Beilin LJ2, Thompson PL10, Prince RL3,9, Hodgson JM. (PubMed)

Sunday 29 December 2019

Cabbage, the Potential Anti inflammatory Healthy Food

By Kyle J. Norton

Anti-inflammation is the process that inhibits inflammation or swelling without affecting the immune property to curb foreign pathogens.

Inflammation is a natural response by the immune system to protect the body against the invasion of stimuli or foreign pathogens.

Acute inflammation is a short-term condition that lasts less than 3 weeks caused by tissue injury, leading to pain, redness, swelling, and heat to the affected area. depending on the size of the injury. Some patients with acute inflammation may also experience the symptom of loss of function.

In acute inflammation, the white blood cells on the first line of defense of the immune system after sensing the danger of an infection in the body through a message from the brain stimulate the production of platelets to cover the site of injury or damage and inflammatory cytokines to kill off all pathogens before they can cause harm to the body.

Most cases of infection are stopped at the acute phase. The wound or injury is slowly recovered.

However, if the immune first line of defense can not completely destroy the invaders within a period of 3 to 8 weeks, it will compromise, leading to low-grade chronic inflammation.

Diseases associated with low-grade chronic inflammation include diabetes, cardiovascular disease, and cancer.

However, in some cases, the overproduction of proinflammatory cytokines may damage nearby healthy cells and tissues, causing the formation of scars.

In severe cases, a protein with duo functions in the production of pro and anti-inflammatory cytokines which produce anti-inflammatory cytokines under normal condition also switch to produce pro-inflammatory cytokines.

Conventionally, the most common use of anti-inflammatory medicines is over counter aspirin, ibuprofen (Advil, Motrin, Nuprin) and other prescription NSAIDs.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.

With an aim to find a natural food for the prevention of diseases involved in inflammation, researchers examined the antioxidant and anti-inflammatory activities of some common cabbage varieties.
According to the tested differentiation,
* Redheads had the highest total antioxidant contents followed by Savoy, Chinese and green heads.
* The Chinese variety had the highest ABTS (2,2-azino-di-(3-ethylbenzthiazoline-sulfonic acid) antioxidant activity, was 5.72 μmol TE/g fw (Trolox equivalent).

* The green variety had the highest DPPH (free radical scavenging activity) antioxidant activity, which was 91.2 μmol TE/g fw.

* The red variety had the highest FRAP (ferric reducing antioxidant power) antioxidant activity, which was 80.8 μmol TE/g fw.

* The total phenol amounts were 17.2-32.6 mM trolox equivalent antioxidant capacity (TEAC) and the total flavonoid amounts were 40.0-74.2 mg quercetin per gram.

* Methanolic extracts of different cabbage heads showed different anti-inflammatory activity values. Chinese, Savoy and green heads had the highest anti-inflammatory activity, while redheads had the lowest.

In other words, all variety of cabbages showed a strong antioxidant and anti-inflammatory activity, depending on the quantity of the contents of the bioactive compound.

Based on the results, researchers wrote, "The results suggest that these varieties of cabbage heads could contribute as sources of important antioxidant and anti-inflammatory related to the prevention of chronic diseases associated with oxidative stress, such as in cancer and coronary artery disease".

Taken altogether, cabbage processed abundantly SFN may be considered a remedy for the prevention and treatment of chronic inflammatory diseases, including cancer and coronary artery disease,  pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cabbage (Brassica oleracea L. var. capitata) phytochemicals with antioxidant and anti-inflammatory potential by Rokayya S1, Li CJ, Zhao Y, Li Y, Sun CH. (PubMed)

Cabbage Inhibits Mitochondrial Dysfunction Caused by Oxidative Stress

By Kyle J. Norton

Mitochondria are the cell that converts food molecules into the energy for the body tissues' needs. Mitochondria produce 90 percent of the energy for body functioning.

Mitochondrial dysfunction is a condition affecting the organelles that generate energy for the cell.

The genetic proposition has been found to alter the process of mitochondria in converting oxygen and food to energy in some people. Acquired mitochondrial dysfunction has been found in patients with Alzheimer’s disease, muscular dystrophy, Lou Gehrig’s disease, diabetes, and cancer.

Acquired mitochondrial dysfunction caused by the long-term use of certain medications such as Metformin, medical conditions such as mitochondrial encephalomyopathy or infection and environmental influences, such as xenochemicals, can lead to less and less energy generated within the cells.

Most common symptoms of mitochondrial dysfunction include poor growth
muscle weakness, muscle pain, low muscle tone, exercise intolerance, vision and/or hearing problems
learning disabilities, delays in development, mental retardation depending on the location of the infected cells.

Diseases associated with mitochondrial dysfunction include Autism, autism-like features Heart, liver or kidney diseases, gastrointestinal disorders, diabetes, neurological problems, thyroid and respiratory (breathing) problems and dementia. 

Conventionally, treatments of mitochondrial dysfunction are totally depending on the causes of the disease.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.

With an aim to find natural food for the protection of mitochondrial function, researchers examined the effects of cabbage extract on oxidative stress in H9c2 cardiomyoblasts.
According to the tested differentiation,
* Cabbage extract protected against H2O2-induced cell death and did not elicit any cytotoxic effects.

* Cabbage extract suppressed ROS production and increased expression of antioxidant proteins (SOD-1, catalase, and GPx).

* Cabbage extract also inhibited apoptotic responses and activation of MAPK proteins (ERK1/2, JNK, and p-38) in oxidative stress-exposed H9c2 cells.

Precisely, cabbage extract preserved mitochondrial functions upon oxidative stress.

Taken altogether, cabbage may be considered a remedy for the protection of mitochondrial dysfunction, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cabbage (Brassica oleracea var. capitata) Protects against H2O2-Induced Oxidative Stress by Preventing Mitochondrial Dysfunction in H9c2Cardiomyoblasts by Yang DK. (PubMed)

Angelica Sinensis In the Treatment of Mammary Gland Hyperplasia in Vivo

By Kyle J. Norton


Mammary gland hyperplasia or hyperplasia of the breast is the benign overgrowth of mammary ductal epithelial cells and interstitial fibers.

Believe it or not, patients with mammary gland hyperplasia are found in 99.3% of the total patients with breast-related diseases, in which 5–10% have the potential to develop breast cancer.

Hyperplasia is the enlargement organ or tissue caused by an increase in the reproduction rate of its cells.

Hyperplasia of the breast is considered an early stage of breast cancer.

According to the statistics, atypical ductal hyperplasia (ADH) is the common form of hyperplasia of the breast found in about 5% to 20% of the diseases.

Although atypical ductal hyperplasia (ADH) is benign, the progression of the condition has been found to induce ductal carcinoma in situ (DCIS) and invasive carcinoma.

Mammary gland hyperplasia doesn't cause symptoms, However, some patients may experience a lump or pain.

Conventionally, most cases of mammary gland hyperplasia are treated by surgery that removes the abnormal cell growth.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a natural compound for the treatment of diseases associated with the breast, researchers examined the effect of acupuncture combined with medication (Rule Granule) on mammary gland hyperplasia in an animal model.

A total of 55 female SD rats were randomized into blank control group (n=10), model group (n=10), acupuncture group (n=11), medication group (n=10), and acupuncture plus medication group (n=9), as follow

* The MGH model was established by muscular injection of E2 benzoate(0.5 mg/kg, once daily for 20 days), followed by injection of P (5 mg/kg) into the lateral muscle of the hind-limb, once daily for 5 days, and the rats of the control group were treated by muscular injection of normal saline at the same site and in the same procedures.

* Acupoint group A composed of bilateral Tianzhong (SI 11), Ganshu (BL 18) and Zusanli (ST 36), and group B composed of Tanzhong (CV 17), and bilateral Wuyi (ST 15) and Hegu (LI 4) were alternatively punctured with filiform needles and stimulated swiftly by twirling the needle in each acupoint for 20-30 sec, once daily for 30 days.

* Rats of the medication group and acupuncture +medication group were treated by gavage of Rule Granule fluid containing Baishao (Paeonia Iactiflora Pall), Danggui (Angelica Sinensis), etc. (1.5 mL/100 g for each rat) and those of the other groups treated by gavage of distilled water (1.5 mL/100 g). The treatment was given once daily for a continuous 30 d. At the end of the experiments,

According to the results of the analysis, the hyperplasia of the mammary gland was found to improve significantly. The serum PRL and E2 contents and the expression of prolactin receptor (PRLR), estrogen receptor (ER) and progesterone receptor (PR) was significantly decreased, and the content of P was notably increased in the acupuncture, medication, and acupuncture plus medication groups relevant to the model group.

Furthermore, acupuncture plus medication were significantly superior to those of both simple medication and simple acupuncture in down-regulating serum PRL and E2 contents and PRLR, ER and PR immunoactivity, as well as in up-regulating serum P content.

Additionally, no significant differences were found between the medication and acupuncture groups. 

Based on the findings, researchers said, "The therapeutic effects of acupuncture plus Rule Granule are better than those of simple acupuncture and simple Rule Granule".

Taken altogether, Herbal Angelica used a combination with other herbal medicine and acupuncture
for the treatment of mammary gland hyperplasia, pending to larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) [Effect of Acupuncture Combined with Gavage of Rule Granule on Serum Prolactin, Estradiol and Progestone Contents and Their Receptor Expression in Breast in Mammary Gland Hyperplasia Rats].[Article in Chinese] by Zhao X1, Qiao D2, Hou M. (PubMed)

Cleaver(Galium aparine) Protects the Cells of Thymus Against Alternation of DNA in Vivo

By Kyle J. Norton

The thymus is a small, irregular-shaped gland in the top part of the chest, just under the breastbone and between the lungs.

The thymus formed part of both the lymphatic system and the endocrine system plays a critical role in the development of T-lymphocytes or T cells, in the immune system through the production of hormones

Unlike most organs, the thymus at its largest in children. Once the children reach puberty, the thymus starts to slowly shrink and replaced by fat.

The most common diseases associated with thymus are myasthenia gravis (MG), pure red cell aplasia (PRCA) and hypogammaglobulinemia.

In other words, the myasthenia gravis is a condition caused by abnormally large thymus that produces antibodies that block or destroy the muscles' receptor sites.

The most common symptoms of thymus gland dysfunction are shortness of breath, cough, chest pain, trouble swallowing, loss of appetite and weight loss, headaches, swelling of head face or neck, a bluish color to the skin and dizziness, according to the American Cancer Society.

Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.

Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.

However, at the advanced stage, cancerous cells can travel a distance away from the original site to induce secondary metastasis.

According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.

The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.

Thymoma and thymic cancer are medical conditions associated with malignant cells form on the outside surface of the thymus due to the alternative of cell DNA.

According to statistics, thymoma is uncommon and occurs in less than 1 person per 1.5 million people develops thymoma. In other words, about 400 Americans suffer from the development of thymoma each year.


Cleaver is a herbaceous annual plant, genus Galium, belonging to the family Rubiaceae, native to North America and Eurasia. The herb has been used over thousands of years in herbal and traditional medicine as mild diuretic and blood and lymphatic cleanser and to treat psoriasis, skin conditions, glands, tonsillitis, bladder infections, prevent small kidney stone, etc.

On finding a potential compound for the treatment of cancer, researchers investigated hot component Diosmetin (DGVL) extracted from the traditional Chinese herb Galium verum L. on the thymus of U14-bearing mice.

According to the tested analysis,
* DGVL inhibited tumor growth and significantly increased the thymus weight compared to control.

* DGVL elevated serum levels of IL-2 and significantly reduced levels of TNF-α, TGF-β1, and IL-10 in dose-dependent manner. 

In other words, DGVL protected the thymus tissues by increasing the anti-inflammatory and decreasing the pro-inflammatory expressions.

* DGVL protected thymus tissue against the proliferation of the tumor growth by inhibiting thymus lymphocyte apoptosis.

* Furthermore, the ratio of CD4(+)/CD8(+) T lymphocytes was significantly increased from 0.69 to 2.29 by treatment with DGVL, observed by the strong immune function.

* The expression of healthy cell death (Fas and FasL) on the thymus was lower in the DGVL treatment group compared to control.



Based on the findings, researchers said, " DGVL can inhibit tumor growth and protect tumor-induced apoptosis of the thymus, and the mechanism is closely associated with reduced cell death in the thymus and a Fas-FasL-dependent pathway".

Taken altogether, herbal cleaver used combination with other herbal medicines may be considered an anti thymus tumor remedy, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective effects of diosmetin extracted from Galium verum L. on the thymus of U14-bearing mice by Zhao R1, Chen Z, Jia G, Li J, Cai Y, Shao X. (PubMed)

#Healthy Food Common Fig or Fig (Ficus carica) Processes Antiviral Activities in Vitro

By Kyle J. Norton

Unlike bacteria, a virus replicates only inside the living cells of an organism. Viruses can infect all types of life forms, including humans and microorganisms, such as bacteria and archaea.

In other words, viruses are made up of a piece of genetic material, such as DNA or RNA enclosed in a coat of protein. Virtual infection is a result of a viral invasion that uses components of invaded cells to multiply, leading to the damages or alternation of the DNA or RNA of the host cells.

Anti-viral effects are the use of certain substances to cause the destruction of a virus.

In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells. The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, will attack the white blood cells of the immune system,

The viral infection has been known to carry over some different stages. After successfully attaching to the host cell, the virus releases its mRNA into the host cell, leading to the recruit of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.

The white blood cells in the systematic immune response in the acute phase of infection stimulate the production of the proinflammatory cytokines to the site of infection with an aim to protect our body by killing off the invaders.


The battle between the immune white blood cell and viral invaders in most cases is in the flavor of the immune system, leading of the death of invaders and healing of the infection.


However, if the immune system can not kill off the invaders with 3 - 8 weeks, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.

According to the statistics provided by the CDC, infectious diseases cause over 15 million visits to physician offices and 3.7 million visits to the emergency department in the US every year.

Fig is a species of F. Carica, belongings to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.

On finding natural compounds for the treatment of infectious diseases, researchers examined the latex of fig fruit (Ficus carica) on skin infections with the possible viral origin.

According to the tested differentiation of 5 extracts (methanolic, hexanoic, ethyl acetate, hexane-ethyl acetate (v/v) and chloroformic) for their antiviral potential activity against herpes simplex type 1 (HSV-1), echovirus type 11 (ECV-11) and adenovirus (ADV) in vitro, the hexanoic and hexane-ethyl acetate (v/v) extracts inhibited multiplication of viruses at concentrations of 78 µg mL(-1).

Furthermore, these two extracts were possible candidates as herbal medicines for herpes virus, echovirus, and adenovirus infectious diseases.

Most importantly, all extracts had no cytotoxic effect on Vero cells at all tested concentrations.

Taken altogether, common fig or fig (Ficus carica)  may be considered a remedy for the prevention and treatment of viral infection, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) In vitro cytotoxic and antiviral activities of Ficus carica latex extracts by Lazreg Aref H1, Gaaliche B, Fekih A, Mars M, Aouni M, Pierre Chaumon J, Said K. (PubMed)

Saturday 28 December 2019

Phytochemical Tocopherols Kill Acute Myeloid Leukemia Cells in Vitro

By Kyle J. Norton

Leukemia is a condition characterized by an abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.

Bone marrow is soft tissue inside the hollow center of the major bone. including spine, pelvis, underarm, leg. etc.

Acute leukemia is a condition caused by a rapid increase in the numbers of extreme immature white blood cells that appear in the bloodstream in the other parts of the body, including tissue and organs.

 Acute leukemia can also be classified into
* Acute lymphoblastic leukemia (ALL)
Acute lymphocytic leukemia (ALL) is a type of cancer with the abnormal growth of extreme immature lymphocytes overproduced by the bone marrow and/or lymphatic system. The condition has a tendency to multiply quickly, leading to the death of normal white blood cells in the bone marrow and/or lymphatic system.

In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.

* Acute myeloid leukemia (AML)
Acute myelogenous leukemia (AML) is a cancer of myelogenous lining caused by the rapid growth of abnormal granulocytes accumulated in the bone marrow, interfering with the normal blood cells. In AML, granulocytes appear immature in the bloodstream.

According to the statistics, in 2019, approximately 21,450 people of all ages including 11,650 men and boys and 9,800 women and girls) in the United States will be diagnosed with AML.

AML is the second most common type of leukemia diagnosed in adults and children, but most cases occur in adults. AML makes up 32% of all adult leukemia cases.

The 5-year survival rate for people 20 and older with AML is approximately 24%. For people younger than 20, the survival rate is 67%.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.


On finding a potential phytochemical for the treatment of leukemia, researchers examined the effect of δ-tocopherol in acute myeloid leukemia.

Compared to other leukemia cell lines, δ-T as low as 20 µM showed a strong activity on AML cell line KG-1.

The δ-T inhibition of AML cell line KG-1 was observed in a set of primary cells collected from patients newly diagnosed with AML.

Furthermore, δ-T also induced apoptosis and cell cycle arrest against KG-1 cells.

The results of δ-T anti-AML activity were attributed to the inhibition of protein cyclin-d1 associated with the G1 phase of the cell cycle arrest and a set of homeobox proteins associated with cancer cell growth and apoptosis.

Taken altogether, tocopherols may be considered a supplement for the prevention and treatment of acute myeloid leukemia pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Reduction in Cell Viability and in Homeobox Protein Levels Following in Vitro Exposure to δ-tocopherol in Acute Myeloid Leukemia by Collins J1, Safah H2, Lobelle-Rich P2, Whaley S3, Campbell S3, Saba NS. (PubMed)