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By Kyle J. Norton Health article writer and researcher; Over 10.000
articles and research papers have been written and published on line,
including world wide health, ezine articles, article base, healthblogs,
selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by
Disilgold.com Named 50 of the best health Tweeters Canada - Huffington
Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as
international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome
is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles
clumping on the ovaries that interferes with the function of the normal
ovaries associated
with a high risk for metabolic disorder(1) as resulting of enlarged
ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight
gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1
in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).
The Causes
The causes of polycystic ovarian syndrome are still unknown(69)(70), but there are some suggestions
1. Genetic predisposition
A genetic predisposition is defined as a genetic mutation of some women
who were born predisposed to certain health problems(75). In this case, it is
polycystic ovarian syndrome(70)(71)(72)(73)(74) .
2. Insulin resistance(82)
Insulin
resistance is defined as abnormal levels of insulin in the blood of a
person found to be associated to women with PCOs(83). It may be caused by certain health problems such as diabetes(76)(77),
abnormal function of pancreas(78)(79) or caused low numbers of the insulin
sensitivity of cells(79)(80), which impair the process of glucose in energy
conversion(81), induced high blood glucose levels in the body, cause of increasing the risks of
ovarian cysts development(83).
3. Obesity(84)
Obesity
is defined as
a person whose BMI index is over 24. As we known, obesity women in most
cases are associated to clinical feature of insulin resistance(76).
According to Università Cattolica del Sacro Cuore, low 25(OH)D
levels(86) accompanied with the degree of adiposity may induce the
causation of PCOs(85).
4. Hyperandrogenism
Hyperandrogenism
is a medical condition characterized by excessive
production and/or secretion of androgens leading to male pattern hair
growth, probably due to mutation in the polymorphism rs12720071 in
women(88). According to Erciyes University, there is a relation between
IR(Insulin resistance) and androgenetic alopecia (AGA)(87), a male
pattern baldness.
Hirsutism develops when follicles in androgen
sensitive areas start to
form thick, pigmented hair as opposed to thin, short, non-pigmented hair
normally seen in those areas in women with PCOs(89). Evaluating
terminal hair growth on the chin or lower abdomen may be a reliable
source for predicting hirsutism, according to Ahvaz Jundishapur
University of Medical Sciences(90).
5. Environmental chemicals
Environment chemicals
endocrine disruptors(91)(92), such as such as xanoestrogen,
and lifestyle(91)(92) can causes over production of
certain hormone and reduction of others, leading to abnormal function
of the reproductive organs including the development of follicles and
increasing the risk of PCOs(93).
6. Food adulteration
Food
adulteration, including mixing, substituting, concealing the quality of
food by mislabeling, putting up decomposed or expired food, and adding
toxic substances(94) can lead to hormone imbalance(98) and distort
the natural process of women
reproductive system(97) and in same cases, result in death(95)(96).
7. Chronic inflammation
Prolonged
inflammation, known as chronic inflammation, leads to a progressive
shift in the type of cells which are present at the site of inflammation
and is characterized by simultaneous destruction and healing of the
tissue from the inflammatory process(99)(100)(101).
8. Disorders of cortisol metabolism
Cortisol is usually
referred
to as the stress hormone, presented in high levels in patients with
schizophrenia and bipolar disorder(104) as it is secreted in large
volume for our body
to response to stress and anxiety(103). Disorders of cortisol
metabolism is
defined as a condition of which cortisol hormone has lost its function
in restoring glucose homeostasis(105) in balancing
insulin and glucagon in the blood stream(107).
According to University College London Hospitals, altered cortisol
metabolism does not seem to be the primary cause of PCOS(102).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
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