Saturday, 15 July 2023

#Phenolic-Rich Extracts (CPREs) From #Hibiscus Process Anti Bacterial and Viral Infection, Researchers say

Kyle J. Norton

Infectious diseases are medical conditions caused by pathogenic microorganisms, including bacteria, viruses, parasites, or fungi.
Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.

In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.

According to the statistic provided by the World Health Organization, infectious diseases were ranked in the top ten causes of death worldwide in 2016.

A bacterial infection is an infected caused bacteria.

Infection can be acute or chronic. In the acute phase of infection, after receiving the messages from the central nervous system related to the danger of microbial infection, the immune macrophages in the first line of defense stimulate the production of blood palette to cover the wound and pro-inflammatory cytokines to the site of the infection to kill off pathogens which try to enter the body.

However, the overproduction of pro-inflammatory cytokines in the acute phase of infection has also killed off or damaged the nearby healthy cells, leading to the formation of scars.

In most cases in a healthy individual, depending on the size of the wound, the immune system can easily eradicate all foreign invaders, and the wound is recovered within days and weeks.

Symptoms of the acute infection include gastrointestinal discomforts, such as congestion vomiting or nausea, diarrhea, short-term joint or muscle pain, fever, headache, skin rash, and cough, Some patients with acute infection also experience symptoms of swollen lymph nodes, an indication of the body is fighting infection.

The most common types of bacterial infections are bacterial meningitis, otitis media, pneumonia, and tuberculosis.

Roselle (Hibiscus sabdariffa) is a species of Hibiscus probably native to West Africa used in traditional Chinese medicine to resolve phlegm and food stagnation and regulate the Liver to aid digestion, promote weight loss, reduce cholesterol, improve circulation, and lower blood pressure.


With an aim to find natural food for the treatment of infectious diseases,, researchers compared the effects of rude, phenolic-rich extracts (CPREs) isolated from different sources, such as Hibiscus sabdariffa (H. sabdariffa, Roselle), Brassica oleracea var. capitata f. Rubra (B. oleracea, red cabbage) and Beta vulgaris (B. Vulgaris).

According to the tested differentiation, the administration of CPREs showed potential antibacterial and antifungal activities.

According to chemical analysis, total anthocyanins content (TAC), total phenolic content (TPC), and total flavonoid content (TFC), and other compounds found in all three CPREs demonstrated strong antimicrobial effects against pathogenic bacteria and fungi.

Hibiscus sabdariffa CPRE (HCPRE) at a dose of 50 μg/mL exhibited signs of asymmetric, wrinkled exterior surfaces, cell deformations, and loss of cell shapes against Staphylococcus aureus DSM 1104 and Klebsiella pneumonia ATCC 43816.

The injection of CPRE also led to cell clumping, malformations, blisters, cell depressions, and diminished cell numbers.

In other words, CPRE induced the death of bacterial cells and loss of cell contents.

Taken altogether, Hibiscus sabdariffa may be considered a remedy for the prevention and treatment of infectious diseases, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antimicrobial Activity and Chemical Constitution of the Crude, Phenolic-Rich Extracts of Hibiscus sabdariffa, Brassica oleracea, and Beta vulgaris by Abdel-Shafi S1, Al-Mohammadi AR2, Sitohy M3, Mosa B1, Ismaiel A1, Enan G1, Osman A. (PubMed)

#PolyphenolFraction (IvE) Isolated from Elecampane Exerts a Strong Cytotoxic Effect on #Cancer, Studies Find

Kyle J. Norton

Genotoxicity is the term associated with chemical agents that damages the genetic information within a cell, causing mutations of cell DNA, a major cause of cancer.
Not all genotoxicity is mutagenicity, However, all mutagens are genotoxic.
Cytotoxicity is the process that induces cell death through toxins.

In other words, cell cytotoxicity is the process to use certain chemicals or mediator cells to destroy living cells.

In cancers, cytotoxicity can be beneficial to humans by destroying the cancer cells and preventing them from proliferation.

However, cytotoxicity induced by oxidative stress due to the imbalanced ratio of free radicals and antioxidant enzymes produced by the body can cause protein, lipid, and cellular damage that leads to chronic low-grade inflammatory diseases and cancer.

Stimulation of overexpression of free radicals and antioxidant production to induce cytotoxicity to the tumors can also cause cancer cell death without damage to nearby healthy cells.

Some researchers suggested that some plant pigments, including herbal medicine lipophilic secondary metabolites, process antioxidant properties in protecting healthy cells against cytotoxicity but also stimulating the expression of free radical cytotoxicity against cancer cells.

In finding a natural ingredient for the prevention and treatment of cancers, scientists examined the polyphenol fraction (IvE) isolated from Elecampane cytotoxic activities.
Elecampane, also known as Horse-heal (Inula helenium) is a perennial composite plant, genus nulla, belonging to Asteraceae, native to Southern Europe, and Asia.

The plant has been used in traditional and herbal medicine in treating bronchitis or emphysema, night sweats, pulmonary tuberculosis, irritating cough, catarrhal discharges, etc.

According to the tested analysis,
* Overall, forty-three secondary metabolites were identified, including the main components caffeic acid and unusual dihydro benzofuran lignans and cinchonain-type phenols, and hydroxycinnamoyl flavonol glycosides.

* The polyphenol fraction (IvE) showed strong antioxidant activity.

* Furthermore, the fraction inhibits cell viability and mitochondrial redox activity of neuroblastoma, hepatoblastoma, and colon carcinoma cells.

* Most importantly, IvE-induced increase of intracellular reactive oxygen species (ROS) to induce apoptosis without harming the healthy cells.

In other words, all phytochemicals found in the fraction work synergistically to exert cytotoxic and antioxidant activities against cancer cells.

Based on the results, researchers suggest, "The obtained results highlighted that inula leaves, nowadays even undervalued and unexplored, could be considered a renewable source of nutraceutical compounds.".

Taken altogether, Elecampane may be considered a remedy for the treatment of various types of cancer, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A nutraceutical extract from Inula viscosa leaves: UHPLC-HR-MS/MS based polyphenol profile, and antioxidant and cytotoxic activities by Brahmi-Chendouh N1, Piccolella S2, Crescente G2, Pacifico F2, Boulekbache L3, Hamri-Zeghichi S3, Akkal S4, Madani K3, Pacifico S. (PubMed)

#Herbal #ElderExtract Processes Cytotoxicity Against #AntiviralInfection Activity, Researchers Suggest

Kyle J. Norton

Infection is a condition caused by a harmful microbial invasion of the body tissues.
A viral infection is a disease caused by the successful entering and multiplying of a virus in the body.

Anti-viral effects are the act of certain substances to cause the destruction of a virus.

In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells.

Similar to bacterial infection, both infections shared common characteristics by spreading through coughing and sneezing and contact with infected people, especially through kissing and sex.

However, the virus may also cause infection by entering the body through wounds and cuts. Most viruses are killed in the acute phase of the infection.

During this phase, the immune system stimulates the constriction of blood vessels in speeding up the production of blood palettes to cover the wound and the production of inflammatory cytokines to the site of infection to fight off bacterial and viral invasion.

The most common viruses that cause infection are hepatitis A, B, and human papillomavirus (HPV) influenza. mumps, and rubella. People with a weakened immune system are susceptible to acute and chronic viral infections.

The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, will attack the white blood cells of the immune system,

The viral infection has been known to carry over some different stages, after successfully attaching to the host cell, the virus releases its mRNA into the host cell, leading to the recruitment of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.

In the battle between the immune white blood cell and viral invaders in most cases and in the flavor of the side of the immune system, the invaders are killed and the infection is healed.

In finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the antiviral activity of Sambucus FormosanaNakai ethanol extract on human coronavirus NL63 (HCoV-NL63).

Elder or Common Elder is a shrub or small tree of the genus Sambucus of 30 species, belonging to the family Adoxaceae, native to the temperate-to-subtropical regions of both the Northern Hemisphere and the Southern Hemisphere.


The herb has been used in traditional and herbal medicine to treat constipation, colic, diarrhea, colds, flu, bronchial and upper respiratory, irritation of the skin, rheumatism, etc.

According to the tested analysis,
* The extract was less cytotoxic and concentration-dependently increased anti-HCoV-NL63 activities, including cytopathicity, sub-G1 fraction, virus yield (IC50 = 1.17 μg/ml), plaque formation (IC50 = 4.67 μg/ml) and virus attachment (IC50 = 15.75 μg/ml).

* Among the phenolic acid constituents in Sambucus FormosanaNakai extract, caffeic acid, chlorogenic acid, and gallic acid sustained the anti-HCoV-NL63 activity that was ranked in the following order of virus yield reduction: caffeic acid (IC50 = 3.54 μM) > chlorogenic acid (IC50 = 43.45 μM) > coumaric acid (IC50 = 71.48 μM).

* Caffeic acid significantly inhibited the replication of HCoV-NL63 in a cell-type independent manner and blocked the virus attachment (IC50 = 8.1 μM).

Based on the results, researchers suggest, "Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 potential; caffeic acid could be the vital component with anti-HCoV-NL63 activity. The finding could be helpful for developing antivirals against HCoV-NL63".

Taken altogether, Elder may be considered a remedy for the treatment of viral infection, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63 by Weng JR1, Lin CS2, Lai HC3, Lin YP4, Wang CY4, Tsai YC4, Wu KC5, Huang SH6, Lin CW7. (PubMed)

#Herbal #Devilsclaw May Process Anti #Migraine Activity, According to Studies

Kyle J. Norton

Migraine headache is one most common headaches associated with a condition of a chronic neurological disorder of moderate to severe headaches.
Nausea usually develops gradually over 5–20 minutes and lasts for less than 60 minutes.

According to the Research Migraine Foundation, nearly 1 in 4 U.S. households includes someone with migraines.

Approximately, 12% of the population suffers from migraines including 18% of American women, 6% of men, and 10% of children experience migraines.

Migraine is most common between the ages of 18 and 44.

Sadly, 1 in 7 people in the world population will develop migraine headaches at some points in their lifetime. And, chronic migraine affects about 2% of the world population.

More precisely, if you are a woman your risk of migraine headaches is 2 times higher in comparison to men.

Some patients during migraine attacks also suffer symptoms of visual disturbances, nausea, vomiting, dizziness, extreme sensitivity to sound, light, touch, and smell, and tingling or numbness in the extremities or face.

Conventional medicine in reduced symptoms of pain during attacks such as Sumatriptan, Rizatriptan,..and Eletriptan may be effective but they may induce certain side effects, including gastrointestinal discomfort, dizziness, drowsiness,... and muscle weakness.

According to the International Headache Society, complications of migraine headaches can be divided into
* Chronic migraine
Chronic migraines are headaches in the absence of medication overuse, occurring on ≥15 days per month for ≥3 months, of which headaches on ≥8 days must fulfill the criteria for migraines and they continue over a long period of time.

* Status migrainosus
Status migrainous is a condition of migraine episodes that persist for less than 3 days, but in most cases, there are periods of relative relief, but these generally last no longer than four hours.

* Persistent aura without infarction (PAWI)
Persistent aura without infarction (PAWI) is a rare complication of migraines with neurological and ophthalmological examinations.

* Migrainous infarction
Migrainous infarction is a rare complication after the usual attacks of migraines with aura.

* Migraine seizures
A migraine seizure is an epileptic seizure that follows a migraine with aura, meeting the definition for migraine with aura, and an epileptic seizure must occur within one hour of the migraine aura.

In finding a natural ingredient for the prevention and treatment of headaches, scientists reviewed literature articles and relevant books using Web of Knowledge and SciVerse Scopus databases.
Devil's claw also known as the wood spider, is a plant of the genus Harpagophytum in the family of Pedaliaceae, native to South Africa.

The plant has been used as an herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidney conditions, etc.

According to tested analysis, devil's claw-derived compounds show considerable promise as novel drugs in migraine prevention and treatment.

However, their antimigraine action was unknown.

And its safety has not been determined.

Based on the results, researchers suggest, "It is necessary to conduct more research to better understand their antimigraine action, to confirm their effectiveness and safety, and to introduce them into clinical practice".

Taken together, Devil's Claw a number of phytochemicals compounds may be considered a remedy for the treatment of migraine, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Natural products and their (semi-)synthetic forms in treatment of migraine: History and current status by Tauchen J. (PubMed)
(2)Migraine Headaches - The Complications by Kyle J. Norton

#EssentialOilExtract from Eyebright Eyebright (Euphrasia) Shows A strong Anti-InfectiousDiseases, Researchers say

Kyle J. Norton

The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections.

Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.

Infectious diseases are a medical condition caused by pathogenic microorganisms, including bacteria, viruses, parasites, or fungi.

Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.

In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.

According to the statistic provided by the World Health Organization, 3 infectious diseases were ranked in the top ten causes of death worldwide in 2016.

More precisely, lower respiratory infections, diarrheal diseases, and tuberculosis induced 3.0 million, 1.4 million, and 1.3 million deaths, respectively.

Conventionally, most cases of infectious diseases except those caused by viruses are treated by antibiotics.

Microorganism, first observed by Anton van Leeuwenhoek in 1675 is a class of microscopic organisms, including a bacterium, virus, or fungus.

Believe or not, single-celled like bacteria, algae, and protozoa, or multicellular, such as algae and fungi can survive under all types of extreme environments.

And less than 1% of bacteria, can invade and cause infection and diseases.

Although the discovery of human antibiotics is medicines that kill or slow the growth of bacteria, however, overuses of antibiotics have been found to induce microbial resistance to certain drugs.

In finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the antimicrobial effects of the essential oil extracted from Eyebright, Euphrasia rostkoviana Hayne (Scrophulariaceae).

Eyebright is one of the species of flowering plants, genus Euphrasia, belonging to the family Orobanchaceae, native to Europe.

The plant has been used in traditional and herbal medicine to treat eye infection and to relieve inflammation caused by colds, coughs, sinus infections, sore throats, and hay fever.

According to the analysis of eye infections induced by Enterococcus faecalis, Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, S. epidermidis, Pseudomonas aeruginosa, and Candida albicans,
* 70 constituents isolated from the essential oil that inhibited infection, the n-hexadecanoic acid (18.47%) was the main constituent followed by thymol (7.97%), myristic acid (4.71%), linalool (4.65%), and anethole (4.09%).

* The essential oil showed antimicrobial effect against all organisms tested with the exception of P. aeruginosa.

* Most importantly, the best activity was observed against all Gram-positive bacteria tested with the minimum inhibitory concentrations of 512 µg/mL.

Based on the results, researchers suggest, "This is the first report on the chemical composition of E. rostkoviana essential oil and its antimicrobial activity".

Taken altogether, Eyebright (Euphrasia) may be considered a remedy for the treatment of microbial infection, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Composition and Antimicrobial Activity of Euphrasia rostkoviana Hayne Essential Oil by Novy P1, Davidova H1, Serrano-Rojero CS1, Rondevaldova J2, Pulkrabek J3, Kokoska L. (PubMed)

#Tocopherols+#Tomatoes Inhibit Parameters Associated with Oxidativestress Against #MammaryCancer in Vivo

Kyle J. Norton

Cancer is a class of diseases associated with the growth of cells disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.

According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.


The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.
The mammary gland located in the breasts of females is responsible for lactation, or the production of milk.

Both males and females have glandular tissue within the breasts, however, in females, the glandular tissue begins to develop after puberty in response to estrogen release.
A mammary tumor is a medical and chronic condition that originated from the milk-producing gland.

Most cases of mammary cancer are first found in the cell on the surface of the inner lining of the milk-producing gland, before penetrating deeper into the layers.

At the advanced stage, the malignant cancer cells can also travel a distance away from the original site to infect other healthy tissues and organs, leading to secondary metastasis.

Epidemiologically, mammary cancer has been found to spread to the colon and the liver.

Most common risk factors of mammary cancer are similar to those of breast cancer, including, aging, physical inactivity, being obese or overweight, family and personal history, having a dense breast, radiation therapy, pregnancy history, genetic proposition, particularly in women who had used drug diethylstilbestrol (DES).

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

In finding a potential phytochemical for the treatment of chronic diseases, researchers examined the synergistic effect of lycopene and tocopherol against oxidative stress and mammary tumorigenesis.

According to the analysis from the administration of lycopene (Lyco) alone or combined with tocopherol (Lyco + Toco) for 90 days against a single oral dose of (50 mg/kg body weight) 7,12-dimethyl[a], benzanthracene (DMBA)-induced oxidative stress and mammary carcinogenesis in female rats,
* There is a significant elevation in the levels of malondialdehyde (MDA) and nitric oxide (NO) in serum and breast tissues of DMBA-injected rats.

* The combined treatment (Lyco + Toco) group showed a potential reduction of these parameters more than Lyco alone group.

* Furthermore, Lyco alone showed significantly higher activities of superoxide dismutase, catalase, and glutathione peroxidase.
In other words, the formation of tumors and angiogenesis in DMBA-induced rats and these abnormal changes were ameliorated by combined treatment with Lyco + Toco.

After taking other factors into account, researchers said, "These results suggested that supplementation of the diet with Lyco and Toco provided antioxidant defense, with strong chemopreventive activity against DMBA-induced mammary tumors".

Taken altogether, tocopherols used alone or combined with lycopene may be considered adjunct therapies in the treatment of breast cancer, pending the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Synergistic effect of lycopene and tocopherol against oxidative stress and mammary tumorigenesis induced by 7,12-dimethyl[a]benzanthracene in female rats by Al-Malki AL1, Moselhy SS, Refai MY. (PubMed)

#BN999, a Fermentation Product of Soybean, Blackbean, and Greenbean Mixture Promotes Anti- Colon Cancer Activity in Vivo

Kyle J. Norton

Cancer is a class of diseases characterized by cell growth irregularly in the tissue of specific organs.
Most cases of primary cancer start in the cells on the surface of the inner lining of specific tissues and organs, before penetrating into deeper layers to form a tumor.

At the advanced stage, the most malignant cancer cell can travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis through blood and fluid circulation.


The colon formed as a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Colon cancer is a chronic condition caused by irregular cell growth in the colon tissue. Most cases of colon cancer start with the alternation of cells' DNA on the surface of the inner lining of colon tissue before proliferating into deeper tissues to form a tumor.

Colon cancer is relatively very common, slowly growing, and progressing cancer.

According to the statistics provided by the American Cancer Society, in 2019, colorectal cancer including colon and rectal cancer is the third most common cancer diagnosed in both men and women in the United States.

The lifetime risk of colon cancer developing is approximately 1 in 23 for men and women, including 71% of colon and 29% of rectal cancer. Believe it or not, only 39% of colon patients are diagnosed with localized-stage disease.

The exact causes of colon cancer are unknown. However, some researchers suggested the promotion of a high-fat diet over the past few decades may have a strong impact on the induction of colon cancer development.


Dr. Milly Ryan-Harshman said, "Consumption of red meat might be related directly to the incidence of CRC or indirectly because a diet high in meat tends to be low in vegetables, fruit, and fiber".


And, "Evidence that diet has an effect on the incidence of CRC is only moderate and might be affected by the multifactorial nature of CRC. Making appropriate choices across food groups, particularly with respect to fruit, vegetables, and fiber, is the key to healthy eating".

Green bean is a genus of Phaseolus Sensu Stricto, containing 55 different species, belongs to the family Fabaceae, and is native to the New World tropics and grown in Europe for its attractive flowers and fleshy immature pods. It can be classified into two major groups, bush beans, and pole beans.

In finding a potent compound that processes chemopreventive activity, researchers examined BN999, a fermentation product of soybean, black bean, and green bean mixture in the inhibition of the growth of human colon cancer.

Application of the mixed product showed a significant effect on inhibiting the growth of mouse CT-26 colon cancer xenografts from a patient's tumor that was implanted into syngenic BALB/c mice, without causing obvious side effects.

Furthermore, BN999 induced apoptosis in colon cancer cells without affecting the healthy cells.

Based on the findings, researchers after taking into account co and confounder wrote, "these data suggest that BN999 has the potential to be used as cancer chemoprevention or therapeutic agent".
Taken altogether, green beans used combined with fermentation products of soybean, the black bean may be used as an adjunct therapy for the prevention of colon cancer, pending the confirmation of a larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Fermentation product of soybean, black bean, and green bean mixture induces apoptosis in a wide variety of cancer cells by Chia JS1, Du JL, Wu MS, Hsu WB, Chiang CP, Sun A, Lu JJ, Wang WB. (PubMed)
(2) Diet and colorectal cancer. Review of the evidence by Milly Ryan-Harshman, Ph.D. RD and Walid Aldoori, MB BCh MPA ScD. (PMC)