By Kyle J. Norton
Functional dyspepsia (FD) is a chronic condition characterized by a burning sensation caused by uncoordinated and ineffectual emptying of the upper digestive tract with no measurable structural abnormalities.
Functional dyspepsia (FD) is subdivided into two types: postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS).
According to statistics, approximately 20-45% of Canadians have such a condition, but only a low percentage of patients seek help from physicians. and functional dyspepsia accounts for 62.5% of dyspepsia in a population of black African patients, compared to other races.
The exact causes of functional dyspepsia are unidentified. Some researchers suggested that excessive acid secretion, inflammation, food allergies, unhealthy lifestyle choice, and long-term use of medications may have strong implications for the onset of the syndrome.
Pain, digestive discomforts such as fullness and bloating, excessive burping, nausea, and sometimes vomiting GERD, and a sour taste in the mouth are the most common symptoms of functional dyspepsia.
If you experience some of the aforementioned symptoms, please make sure you check with your doctor to rule out the possibility.
Some researchers suggested that unhealthy dietary habits are one of the major risk factors associated with the onset of FD in the world.
Dr. Ji-Hao Xu, the lead scientist in the assessment of dietary habits in the risk of FD, wrote, "Unhealthy dietary habits were more prevalent in the FD group than in the control groups (75.86% versus 37.50%; p<0.001). FD was found to be associated with irregular mealtime, dining out, fatty food, sweet food, and coffee (p<0.05). The impact of each dietary factor varied with FD subtypes".
And, "Certain types of dietary habits were positively correlated with the prevalence of FD. FD subtypes showed relatively different associations with dietary factors".
The finding strongly suggested by following a healthy diet pattern, FD may be preventable.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
In the finding of natural therapeutics for the treatment of functional dyspepsia (FD), researchers compared the efficacy of ginger and artichoke supplementation (SG) versus placebo in the treatment of FD.
The prospective multicentre, double-blind, randomized, placebo-controlled, parallel-group comparison of the supplement and placebo over a period of 4 weeks included 126 FD patients given 2 capsules/day (before lunch and dinner (supplementation/placebo: 65/61).
After 14 days, supplement treatment showed a significant amelioration of FD, compared to placebo.
SG treatment group also showed a significant reduction of nausea, epigastric fullness, epigastric pain, and bloating compared to the placebo.
Dr.Giacosa A, the lead scientist wrote, "The association between ginger and artichoke leaf extracts appears safe and efficacious in the treatment of FD and could represent a promising treatment for this disease".
In order to reveal more information about artichoke anti-FD property, researchers assessed the efficacy of artichoke leaf extract (ALE) in the treatment of patients with functional dyspepsia (FD).
The double-blind, randomized controlled trial (RCT) included 247 patients with functional dyspepsia treated with either a commercial ALE preparation (2 x 320 mg plant extract t.d.s.) or a placebo.
ALE improved the overall symptom significantly over the 6 weeks compared to the placebo
Similarly, patients treated with ALE also showed significantly greater improvement in the global quality-of-life scores (NDI) compared to the placebo.
Dr. Holtmann G, the lead scientist after taking into account co and confounders wrote in the final report, "the ALE preparation tested was significantly better than the placebo in alleviating symptoms and improving the disease-specific quality of life in patients with functional dyspepsia".
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of functional dyspepsia (FD), pending the confirmation of a larger sample and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The Effect of Ginger (Zingiber Officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial by Giacosa A1, Guido D2, Grassi M2, Riva A3, Morazzoni P3, Bombardelli E3, Perna S4, Faliva MA4, Rondanelli M. (PubMed)
(2) Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial by Holtmann G1, Adam B, Haag S, Collet W, Grünewald E, Windeck T. (PubMed)
(3) Certain Dietary Habits Contribute to the Functional Dyspepsia in South China Rural Area by Xu JH1, Lai Y1, Zhuang LP2, Huang CZ1, Li CQ1, Chen QK1, Yu T1. (PubMed)
Saturday, 9 July 2022
Thursday, 7 July 2022
Phytochemical Beta-Sitosterol May Process Anti Prostate Cancer Activity
By Kyle J. Norton
The prostate warped around the urethra is a gland of the male reproductive system found in front of the rectum and just below the bladder and responsible for making some of the semen that carries sperm.
The prostate warped around the urethra is a gland of the male reproductive system found in front of the rectum and just below the bladder and responsible for making some of the semen that carries sperm.
The muscle of the prostate gland also plays a critical in nourishing and protecting sperm by secreting fluid in perm ejaculation into the urethra.
Prostate cancer is a medical and chronic condition caused by cell growth irregular in the prostate gland. Most cases of prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during Physical (rectum) exams.
Most cases of prostate cancer begin in the cells on the surface of the inner lining of the prostate tissue before penetrating into deeper layers to induce colonization.
At the advanced stage, the prostate cancer cells can spread to distant parts of the body, leading to secondary metastasis.
Prostate cancer is a medical and chronic condition caused by cell growth irregular in the prostate gland. Most cases of prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during Physical (rectum) exams.
Most cases of prostate cancer begin in the cells on the surface of the inner lining of the prostate tissue before penetrating into deeper layers to induce colonization.
At the advanced stage, the prostate cancer cells can spread to distant parts of the body, leading to secondary metastasis.
According to the statistics, prostate cancer is the most common cancer among men particularly older over 65, after skin cancer. in 2019, approximately 174,650 men in the US will be diagnosed with prostate cancer.
The average age of diagnosis is 66.
The most common symptoms of the prostate at the later stage are frequent urination and weak or interrupted urine flow due to the tumor that affects the tube surrounded by the prostate.
In some cases, patients may experience symptoms of blood in the urine and pain due to the oversize tumor that has pressed on the nearby blood vessels and nerve cells.
The new onset of erectile dysfunction is also common in patients with prostate cancer.
However, the fortified version of the extract that contained higher levels of isovanillin, linolenic acid, and β-sitosterol had a stronger effect on the cell death rate, compared to GZ17.
More importantly, GZ17 showed no toxic effects on healthy cells in the doses that were toxic to treated cancer cells.
In NU/NU mice with xenograft prostate tumors, GZ17 treatment had a dramatic inhibition of tumor progression, compared to tumors steadily growing in the control group through the 3 weeks.
In some cases, patients may experience symptoms of blood in the urine and pain due to the oversize tumor that has pressed on the nearby blood vessels and nerve cells.
The new onset of erectile dysfunction is also common in patients with prostate cancer.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belonging to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.
On finding a potential phytochemical for the prevention and treatment of cancer, researchers examined the effect of Arum Palaestinum extract containing additional isovanillin, linolenic acid, and β-sitosterol (GZ17) on prostate cancer in an animal model.
The study included male NU/NU mice (8 weeks old) with xenograft tumors derived from the prostate cancer cell line treated daily with 1000 mg/kg body weight gavage of the suspension GZ17 with control mice (10 mice in each group) received a vehicle in the same manner and volume.
On finding a potential phytochemical for the prevention and treatment of cancer, researchers examined the effect of Arum Palaestinum extract containing additional isovanillin, linolenic acid, and β-sitosterol (GZ17) on prostate cancer in an animal model.
The study included male NU/NU mice (8 weeks old) with xenograft tumors derived from the prostate cancer cell line treated daily with 1000 mg/kg body weight gavage of the suspension GZ17 with control mice (10 mice in each group) received a vehicle in the same manner and volume.
Arum Palaestinum extract GZ17 showed a decline in the number of live prostates cancer cells in a dose/dependent manner after a 24 h exposure at doses of 0.015 to 6.25 mg/mL.
However, the fortified version of the extract that contained higher levels of isovanillin, linolenic acid, and β-sitosterol had a stronger effect on the cell death rate, compared to GZ17.
At the highest dose, GZ17 increased cell death from 30 % to 55 % compared to the vehicle control that had no effect on cell numbers.
Finally, according to the tumor assays, the rate of tumor volume increase was 73 mm(3)/day for the vehicle group compared to only 24 mm(3)/day in GZ17 treated mice.
Based on the results, researchers said, "Fortified Arum palaestinum Boiss caused a reduction in live cells within prostate cancer spheroids and blocked tumor growth in xenografted prostate tumors in mice without signs of toxicity".
Taken altogether, beta-Sitosterol used a combination with other herbal medicine and phytochemicals may be considered a supplement for the prevention and treatment of prostate cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice by Cole C1, Burgoyne T2, Lee A3,4, Stehno-Bittel L5,6, Zaid G. (PubMed)
Taken altogether, beta-Sitosterol used a combination with other herbal medicine and phytochemicals may be considered a supplement for the prevention and treatment of prostate cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice by Cole C1, Burgoyne T2, Lee A3,4, Stehno-Bittel L5,6, Zaid G. (PubMed)
Sunday, 3 July 2022
Omega-3 Fatty Acids Protect and Improve Cognitive Functions
By Kyle J. Norton
The central nervous system (CNS) is a complex network that controls most functions of the body and mind consisting of two parts, the brain, and the spinal cord.
Cognition is the process of the brain functioning associated with the attention of working memory, producing and comprehending language, learning, reasoning, problem-solving, and decision making.
On the other hand, cognitive impairment, depending on the severity of the condition, the infected person has trouble remembering, learning new things, concentrating, or making decisions that affect the quality of their everyday life.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the protection of cognitive functioning, researchers examined the effect of ω3 PUFA on an animal model that exhibits severe cognitive impairments (learning, memory).
The study included adult male mouse lemurs fed for 5 months on a control diet or on a diet supplemented with long-chain ω3 PUFA (n = 6 per group).
In vivo, ω3 PUFA supplementation lowered the anxiety in tested mice compared to control.
The central nervous system (CNS) is a complex network that controls most functions of the body and mind consisting of two parts, the brain, and the spinal cord.
On the other hand, cognitive impairment, depending on the severity of the condition, the infected person has trouble remembering, learning new things, concentrating, or making decisions that affect the quality of their everyday life.
Acute cognitive impairment is a short-term health problem caused by drug toxicity and withdrawal, electrolyte disturbance, lack of drugs, liver disease, infection, reduced sensor input, intracranial urinary retention/fecal impaction, or myocardial/metabolic/pulmonary. An acute cognitive deficit may be recovered if the cause is found.
Chronic cognitive impairment is a permanent medical condition caused by the gradual or permanent loss of neurons, leading to problems with language, ideomotor and constructive praxis, visual gnosis, spatial attention, learning abilities, and executive functions.
In the elderly, most cases of cognitive impairment are associated with neurodegenerative diseases and long-term use of medication, including Alzheimer's disease.
However, malnutrition, hormone imbalance such as thyroid hormone, mental illness, and substance abuse, particularly, in brain damage or injury are some of the major and prevalent risk factors that can cause the early onset of cognitive impairment.
Chronic cognitive impairment is a permanent medical condition caused by the gradual or permanent loss of neurons, leading to problems with language, ideomotor and constructive praxis, visual gnosis, spatial attention, learning abilities, and executive functions.
In the elderly, most cases of cognitive impairment are associated with neurodegenerative diseases and long-term use of medication, including Alzheimer's disease.
However, malnutrition, hormone imbalance such as thyroid hormone, mental illness, and substance abuse, particularly, in brain damage or injury are some of the major and prevalent risk factors that can cause the early onset of cognitive impairment.
There is no single cause of chronic cognitive impairment. An increase in age, genetic preposition, and certain medical conditions, such as diabetes, high blood cholesterol, pressure, being obese, and lack of exercise are some prevalent factors found in patients with chronic cognitive deficits.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
On finding a potential phytochemical for the protection of cognitive functioning, researchers examined the effect of ω3 PUFA on an animal model that exhibits severe cognitive impairments (learning, memory).
In cognitive parameters assays, ω3-supplementation mouses showed a better performance in a reference spatial memory task (80% of successful trials vs 35% in controls, p<0.05) and reduced spontaneous locomotor activity by 31%.
Importantly, chronic dietary ω3 PUFA supplementation positively impacts anxiety and cognitive performances in the adult mouse lemur.
Based on the findings, researchers said, "The supplementation of human food with ω3 fatty acids may represent a valuable dietary strategy to improve behavioral and cognitive functions".
Taken altogether, Omega-3 fatty acids may be considered a functional supplement for the prevention and treatment of cognitive functions, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 fatty acids from fish oil lower anxiety, improve cognitive functions and reduce spontaneous locomotor activity in a non-human primate by Vinot N1, Jouin M, Lhomme-Duchadeuil A, Guesnet P, Alessandri JM, Aujard F, Pifferi F. (PubMed)
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 fatty acids from fish oil lower anxiety, improve cognitive functions and reduce spontaneous locomotor activity in a non-human primate by Vinot N1, Jouin M, Lhomme-Duchadeuil A, Guesnet P, Alessandri JM, Aujard F, Pifferi F. (PubMed)
Thursday, 30 June 2022
Bioactive Compound Curcumin Found in Herbal Turmeric Inhibits the Risk of Peripheral Arterial Disease In Vitro
By Kyle J. Norton
Peripheral artery disease is a common circulatory condition caused by narrowed arteries that reduce blood flow to your limbs.
Most cases of peripheral artery disease have been associated with the accumulation of plaque in thicking and hardening the arteries, a leading cause of atherosclerosis.
The most common prevalent factors associated with peripheral artery disease are tobacco, physical inactivity, and an unhealthy diet with high in fat, processed food, and red meat and low in fruits and vegetables.
Most patients with peripheral arterial disease are asymptomatic or experience a mild case of pain in the leg while walking. However, as the disease progression, some patients may also experience symptoms of leg numbness or weakness, coldness in their lower leg or foot, sores on their toes, feet or legs that won't heal, a change in the color of their legs, slower growth of your toenails and shiny skin on your legs.
Some men also experience the syndrome of erectile dysfunction in severe cases.
Conventionally, treatment of peripheral arterial disease is focusing improving symptoms, such as leg pain, and quality of life and stopping the progression of atherosclerosis associated with the risk of heart attack and stroke, including medication to lower cholesterol, blood pressure, and blood sugar.
In some cases, surgery may be necessary to treat peripheral artery disease if patients experience claudication that does not respond to medicine.
Some researchers in the investigation of the effect of the heart-healthy diet on peripheral arterial disease wrote, "Peripheral arterial disease (PAD) is a burdensome cardiovascular condition that results from chronic inflammatory insults to the arterial vasculature".
And, "The nutrients reviewed included omega-3 polyunsaturated fatty acids (n-3 PUFAs), folate and B-series vitamins, and anti-oxidants. The diet plans described include the DASH diet, Mediterranean diet, low-fat diet, low carbohydrate diet, Dr. Dean Ornish’s Spectrum® Diet, and Dr. Andrew Weil’s Anti-Inflammatory Diet".
In other words, by changing to a healthy diet with more fruits and vegetables and less red meat, saturated and trans fat, and processed foods peripheral arterial disease may be preventable.
Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
On findings of a potential compound for the treatment of heart diseases, researchers examined curcumin treatment improves tissue repair and perfusion recovery in a mouse model of diabetic PAD.
Mice with PAD selected for the study with a normal glycaemic profile treated with curcumin, improved perfusion recovery, observed by the increased capillary density and elevated microRNA (miR)-93 expression in the ischemic muscle tissue.
In vitro, cultured endothelial cells under simulated ischemia, treated with curcumin improved endothelial cell viability and enhanced tube formation.
However, improved endothelial cell viability and enhanced tube formation were inhibited in the presence of the miR-93 inhibitor, regardless of the administration of curcumin.
Based on the findings, researchers said, "curcumin had beneficial effects in non-diabetic PAD by improving angiogenesis, which may have been achieved partially via the promotion of miR-93 expression".
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of peripheral arterial disease, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin improves perfusion recovery in experimental peripheral arterial diseaseby upregulating microRNA-93 expression by Zhang J1,2, Wang Q1, Rao G1, Qiu J1, He R. (PubMed)
(2) Advancing Beyond the ‘Heart-Healthy Diet’ for Peripheral Arterial Disease by Emily V. Nosova,1,2 Michael S. Conte,1,3 and S. Marlene Grenon. (PMC)
Peripheral artery disease is a common circulatory condition caused by narrowed arteries that reduce blood flow to your limbs.
Most cases of peripheral artery disease have been associated with the accumulation of plaque in thicking and hardening the arteries, a leading cause of atherosclerosis.
The most common prevalent factors associated with peripheral artery disease are tobacco, physical inactivity, and an unhealthy diet with high in fat, processed food, and red meat and low in fruits and vegetables.
Most patients with peripheral arterial disease are asymptomatic or experience a mild case of pain in the leg while walking. However, as the disease progression, some patients may also experience symptoms of leg numbness or weakness, coldness in their lower leg or foot, sores on their toes, feet or legs that won't heal, a change in the color of their legs, slower growth of your toenails and shiny skin on your legs.
Some men also experience the syndrome of erectile dysfunction in severe cases.
Conventionally, treatment of peripheral arterial disease is focusing improving symptoms, such as leg pain, and quality of life and stopping the progression of atherosclerosis associated with the risk of heart attack and stroke, including medication to lower cholesterol, blood pressure, and blood sugar.
In some cases, surgery may be necessary to treat peripheral artery disease if patients experience claudication that does not respond to medicine.
Some researchers in the investigation of the effect of the heart-healthy diet on peripheral arterial disease wrote, "Peripheral arterial disease (PAD) is a burdensome cardiovascular condition that results from chronic inflammatory insults to the arterial vasculature".
And, "The nutrients reviewed included omega-3 polyunsaturated fatty acids (n-3 PUFAs), folate and B-series vitamins, and anti-oxidants. The diet plans described include the DASH diet, Mediterranean diet, low-fat diet, low carbohydrate diet, Dr. Dean Ornish’s Spectrum® Diet, and Dr. Andrew Weil’s Anti-Inflammatory Diet".
In other words, by changing to a healthy diet with more fruits and vegetables and less red meat, saturated and trans fat, and processed foods peripheral arterial disease may be preventable.
Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
On findings of a potential compound for the treatment of heart diseases, researchers examined curcumin treatment improves tissue repair and perfusion recovery in a mouse model of diabetic PAD.
Mice with PAD selected for the study with a normal glycaemic profile treated with curcumin, improved perfusion recovery, observed by the increased capillary density and elevated microRNA (miR)-93 expression in the ischemic muscle tissue.
In vitro, cultured endothelial cells under simulated ischemia, treated with curcumin improved endothelial cell viability and enhanced tube formation.
However, improved endothelial cell viability and enhanced tube formation were inhibited in the presence of the miR-93 inhibitor, regardless of the administration of curcumin.
Based on the findings, researchers said, "curcumin had beneficial effects in non-diabetic PAD by improving angiogenesis, which may have been achieved partially via the promotion of miR-93 expression".
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of peripheral arterial disease, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin improves perfusion recovery in experimental peripheral arterial diseaseby upregulating microRNA-93 expression by Zhang J1,2, Wang Q1, Rao G1, Qiu J1, He R. (PubMed)
(2) Advancing Beyond the ‘Heart-Healthy Diet’ for Peripheral Arterial Disease by Emily V. Nosova,1,2 Michael S. Conte,1,3 and S. Marlene Grenon. (PMC)
Sunday, 26 June 2022
Omega-3 Fatty Acids Reduce the Risk of Postpartum Depression (PPD)
By Kyle J. Norton
Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, and illness.
Normally the symptoms will go away on their own in a short period of time (Baby blue symptoms). In some women, the symptoms get more serve every day and do not go away which can lead to the onset of postpartum depression.
Since postpartum depression is a serious mental illness, it can interfere with your ability to look after yourself, your child, and your daily activities performance, etc.
If left untreated, it can badly affect your newborn such as loving one minute and being withdrawn the next, do not respond to the needs of the baby, leading to the insecurity attachment(a negative feeling when they are baby), lack of emotional bond between the mother and the baby, etc
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical that processed anti-psychological activity researchers examined and compared the effects of omega-3 polyunsaturated fatty acid supplementation on depression during pregnancy or postpartum depression (PPD) after childbirth.
According to the identified studies, omega-3 fatty acid deficiency, due to inadequate intake, and fast depletion during pregnancy and lactation were associated with one of the risk factors of PPD.
Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, and illness.
Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate.
Depression may be a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself.
The mild case of depression can be defeated by a variety of self-care techniques. Others require the treatment of medication, such as antidepressant medications and psychotherapy that help to reduce and sometimes eliminate the symptoms of depression.
Postpartum depression (postnatal depression), is a type of clinical depression, that affects women after childbirth. Normally this nervous tension occurs in women in the first new months of pregnancy, but in some women, it can last after childbirth.
The rate of occurrence is between 5 -25%, depending on the uniqueness of each woman. In men, the occurrence of postpartum depression is uncleared, affecting between 1% and 25%.
Normally the symptoms will go away on their own in a short period of time (Baby blue symptoms). In some women, the symptoms get more serve every day and do not go away which can lead to the onset of postpartum depression.
If left untreated, it can badly affect your newborn such as loving one minute and being withdrawn the next, do not respond to the needs of the baby, leading to the insecurity attachment(a negative feeling when they are baby), lack of emotional bond between the mother and the baby, etc
On finding a potential phytochemical that processed anti-psychological activity researchers examined and compared the effects of omega-3 polyunsaturated fatty acid supplementation on depression during pregnancy or postpartum depression (PPD) after childbirth.
The study included a search of medical literature published on MEDLINE, PubMed, PsycINFO, and the Cochrane Collaboration Registry of Controlled Trials, etc. through July 2017.
Additionally, the elevated neuroinflammation (elevated pro-inflammatory cytokines) and aberrant neurotransmission (low serotonergic transmission activity) also increased the risk of PPD.
Supplementation with eicosapentaenoic acid (EPA)-rich oil showed effectively reduces depression during pregnancy and PPD after childbirth.
However, long-term treatment with docosahexaenoic acid (DHA)-rich oil could also be effective in reducing the risk of PPD in healthy women, but not in lactating women.
Moreover, Supplementation of DHA-rich oil to women begun at pregnancy and continued after childbirth showed no beneficial effect on depression.
Based on the evidence, researchers wrote, "Dietary supplementation with omega-3 fatty acids rich in EPA during pregnancy or postpartum reduces some symptoms associated with depression. DHA supplementation to healthy pregnant women can also reduce the risk of PPD".
Taken altogether, Omega-3 fatty acids may be considered functional foods for the prevention of postpartum depression (PPD), pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 polyunsaturated fatty acid supplementation in prevention and treatment of maternal depression: Putative mechanism and recommendation by Hsu MC1, Tung CY2, Chen HE. (PubMed)
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 polyunsaturated fatty acid supplementation in prevention and treatment of maternal depression: Putative mechanism and recommendation by Hsu MC1, Tung CY2, Chen HE. (PubMed)
Wednesday, 22 June 2022
Beta-Sitosterol Found in Japanese Arrowroot or Chinese Arrowroot Shows an Effect on Menopausal Symptoms In Vivo
By Kyle J. Norton
Menopause is a condition in which a woman is in the transition stage of permanent cessation of the ovary's functions in egg production because of less production of estrogen and progesterone, signaling the end of the reproductive phase of a woman's life.
In menopause, menstruation has become irregular and slowly stops over time, but in some women, menstrual flow comes to a sudden halt.
Some researchers suggested that you officially enter the stage of menopause if you have gone 12 months without a menstrual period.
Compared to menopause, peri-menopause is a condition in which women experience an irregular menstrual cycle due to the hormonal decline gradually, including shorter, longer, heavy, light periods and some menopause symptoms.
Perimenopause, in fact, is a transition stage to menopause, and the length of this transition can be 3-10 years or longer. Once you have no menstrual period in 12 consecutive months, you have officially entered 12 months of menopause already.
Women enter the menopause stage differently, but the average age is 51 in the United States.
Women with ovarian failure or removed may experience symptoms of menopause at the early age of 38.
Symptoms of menopause are the result of the gradually reduced production of estrogen and progesterone, the 2 most abundant hormones in childbearing-age women.
Most women in the Western world experience symptoms of hot flashes and emotional symptoms of menopause may disrupt your sleep, lower your energy or affect emotional health.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.
In finding a potential phytochemical for the treatment of menopausal symptoms, researchers elucidated the biological activities of Pueraria lobata (PL) on menopause-related metabolic diseases.
According to the results of ovariectomized (OVX) rats as a postmenopausal model that was administered PL at different doses (50, 100, and 200 mg/kg),* The decreased uterine weights and PPAR-γ (peroxisome proliferator-activated receptor-gamma) mRNA expression in the thigh muscle found in menopausal females in the ovariectomized (OVX) rats were significantly recovered after PL administration.
* Furthermore, PL also significantly alleviated OVX-induced increases in total cholesterol, triglyceride, alanine aminotransferase (ALT/GPT), and aspartate aminotransferase (AST/GOT) levels.
More precisely, the efficacy of Pueraria lobata (PL) on menopause-related metabolic diseases was attributed to four potential active compounds, including beta-sitosterol.
In other words, the chemical compounds exerted a strong activity against multiple targets among female sex hormone-related pathways, including the estrogen signaling pathways, progesterone-mediated oocyte maturation, oxytocin signaling pathways, and prolactin signaling pathways.
Based on the findings, researchers said, "PL improved various indicators associated with lipid metabolism in the postmenopausal animal model".
Beta-Sitosterol may be considered a remedy for the prevention and treatment of menopausal symptoms, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Investigating the Systems-Level Effect of Pueraria lobata for Menopause-Related Metabolic Diseases Using an Ovariectomized Rat Model and Network Pharmacological Analysis by Oh JH1, Baek SE2, Lee WY1, Baek JY3,4, Trinh TA3, Park DH3, Lee HL5, Kang KS3, Kim CE1, Yoo JE. (PubMed)
Menopause is a condition in which a woman is in the transition stage of permanent cessation of the ovary's functions in egg production because of less production of estrogen and progesterone, signaling the end of the reproductive phase of a woman's life.
In menopause, menstruation has become irregular and slowly stops over time, but in some women, menstrual flow comes to a sudden halt.
Some researchers suggested that you officially enter the stage of menopause if you have gone 12 months without a menstrual period.
Compared to menopause, peri-menopause is a condition in which women experience an irregular menstrual cycle due to the hormonal decline gradually, including shorter, longer, heavy, light periods and some menopause symptoms.
Perimenopause, in fact, is a transition stage to menopause, and the length of this transition can be 3-10 years or longer. Once you have no menstrual period in 12 consecutive months, you have officially entered 12 months of menopause already.
Women enter the menopause stage differently, but the average age is 51 in the United States.
Women with ovarian failure or removed may experience symptoms of menopause at the early age of 38.
Symptoms of menopause are the result of the gradually reduced production of estrogen and progesterone, the 2 most abundant hormones in childbearing-age women.
Most women in the Western world experience symptoms of hot flashes and emotional symptoms of menopause may disrupt your sleep, lower your energy or affect emotional health.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.
In finding a potential phytochemical for the treatment of menopausal symptoms, researchers elucidated the biological activities of Pueraria lobata (PL) on menopause-related metabolic diseases.
According to the results of ovariectomized (OVX) rats as a postmenopausal model that was administered PL at different doses (50, 100, and 200 mg/kg),* The decreased uterine weights and PPAR-γ (peroxisome proliferator-activated receptor-gamma) mRNA expression in the thigh muscle found in menopausal females in the ovariectomized (OVX) rats were significantly recovered after PL administration.
* Furthermore, PL also significantly alleviated OVX-induced increases in total cholesterol, triglyceride, alanine aminotransferase (ALT/GPT), and aspartate aminotransferase (AST/GOT) levels.
More precisely, the efficacy of Pueraria lobata (PL) on menopause-related metabolic diseases was attributed to four potential active compounds, including beta-sitosterol.
In other words, the chemical compounds exerted a strong activity against multiple targets among female sex hormone-related pathways, including the estrogen signaling pathways, progesterone-mediated oocyte maturation, oxytocin signaling pathways, and prolactin signaling pathways.
Based on the findings, researchers said, "PL improved various indicators associated with lipid metabolism in the postmenopausal animal model".
Beta-Sitosterol may be considered a remedy for the prevention and treatment of menopausal symptoms, pending the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Investigating the Systems-Level Effect of Pueraria lobata for Menopause-Related Metabolic Diseases Using an Ovariectomized Rat Model and Network Pharmacological Analysis by Oh JH1, Baek SE2, Lee WY1, Baek JY3,4, Trinh TA3, Park DH3, Lee HL5, Kang KS3, Kim CE1, Yoo JE. (PubMed)
Sunday, 19 June 2022
Tocopherols Inhibits The Liver Oxidative Stress
By Kyle J. Norton
Oxidative stress is a condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.
In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.
There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, and oxidative burst from activated macrophages, particularly, the free radicals chain reaction.
Sadly, a prolonged period of oxidative stress present in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.
Certain chronic diseases are found to be associated with oxidative stress, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial
According to the analysis,
* L-AA (100 µM) and α-TOC (50 µM) recovered As2O3 (10 µM) cytotoxicity.
* As2O3 treatment showed an increase in lipid peroxidation and depletion in antioxidant status, mitochondrial transmembrane potential, and values of total antioxidant capacity.
* Cotreatment of antioxidant vitamins with As2O3 resulted in a significant reversal of oxidative stress markers.
Oxidative stress is a condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.
In other words, oxidative stress is either caused by overexpression of free radicals or depletion of antioxidant enzymes in the body.
Some researchers suggested that oxidative stress may also arise due to the chain reaction of free radicals in which free radicals donate or intercept an electron from other stable molecules.
Long-term oxidative stress present in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including cardiovascular disease, diabetes, and cancer.
Some researchers suggested that oxidative stress may also arise due to the chain reaction of free radicals in which free radicals donate or intercept an electron from other stable molecules.
Long-term oxidative stress present in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including cardiovascular disease, diabetes, and cancer.
In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.
There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, and oxidative burst from activated macrophages, particularly, the free radicals chain reaction.
Sadly, a prolonged period of oxidative stress present in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.
Certain chronic diseases are found to be associated with oxidative stress, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial
Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, seed or nut oils, etc.
On finding a potential phytochemical for the treatment of diseases associated with oxidative stress, researchers examined the curative efficacy of L-Ascorbic acid (L-AA) and α-Tocopherol (α-TOC) against Arsenic trioxide (As2O3) toxicity using immortalized human Chang liver cells.
On finding a potential phytochemical for the treatment of diseases associated with oxidative stress, researchers examined the curative efficacy of L-Ascorbic acid (L-AA) and α-Tocopherol (α-TOC) against Arsenic trioxide (As2O3) toxicity using immortalized human Chang liver cells.
* L-AA (100 µM) and α-TOC (50 µM) recovered As2O3 (10 µM) cytotoxicity.
* As2O3 treatment showed an increase in lipid peroxidation and depletion in antioxidant status, mitochondrial transmembrane potential, and values of total antioxidant capacity.
Based on the results, researchers said, "substantiate the effect of antioxidant vitamins in protecting the hepatocytes from oxidative stress which may be attributed through Nrf2 (Nuclear factor erythroid 2-related factor 2) mediated upregulation of Bcl2 (B-cell lymphoma 2) expression".
Taken altogether, tocopherols may be considered a supplement for reducing the risk of liver oxidative stress, pending the confirmation of the larger sample size and multicenter human study.
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) L-Ascorbic Acid and α-Tocopherol Reduces Hepatotoxicity Associated with Arsenic Trioxide Chemotherapy by Modulating Nrf2 and Bcl2 Transcription Factors in Chang liver Cells by Vineetha RC1, Archana V1, Binu P1, Arathi P1, Nair RH. (PubMed)
Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) L-Ascorbic Acid and α-Tocopherol Reduces Hepatotoxicity Associated with Arsenic Trioxide Chemotherapy by Modulating Nrf2 and Bcl2 Transcription Factors in Chang liver Cells by Vineetha RC1, Archana V1, Binu P1, Arathi P1, Nair RH. (PubMed)
Subscribe to:
Posts (Atom)