Omega-3 Fatty Acids Protect and Improve Cognitive Functions

By Kyle J. Norton

The central nervous system (CNS) is a complex network that controls most functions of the body and mind consisting of two parts, the brain, and the spinal cord.

Cognition is the process of the brain functioning associated with the attention of working memory, producing and comprehending language, learning, reasoning, problem-solving, and decision making.

On the other hand, cognitive impairment, depending on the severity of the condition, the infected person has trouble remembering, learning new things, concentrating, or making decisions that affect the quality of their everyday life.

Acute cognitive impairment is a short-term health problem caused by drug toxicity and withdrawal, electrolyte disturbance, lack of drugs, liver disease, infection, reduced sensor input, intracranial urinary retention/fecal impaction, or myocardial/metabolic/pulmonary. An acute cognitive deficit may be recovered if the cause is found.

Chronic cognitive impairment is a permanent medical condition caused by the gradual or permanent loss of neurons, leading to problems with language, ideomotor and constructive praxis, visual gnosis, spatial attention, learning abilities, and executive functions.

In the elderly, most cases of cognitive impairment are associated with neurodegenerative diseases and long-term use of medication, including Alzheimer's disease.

However, malnutrition, hormone imbalance such as thyroid hormone, mental illness, and substance abuse, particularly, in brain damage or injury are some of the major and prevalent risk factors that can cause the early onset of cognitive impairment.

There is no single cause of chronic cognitive impairment. An increase in age, genetic preposition, and certain medical conditions, such as diabetes, high blood cholesterol, pressure, being obese, and lack of exercise are some prevalent factors found in patients with chronic cognitive deficits.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the protection of cognitive functioning, researchers examined the effect of ω3 PUFA on an animal model that exhibits severe cognitive impairments (learning, memory).

The study included adult male mouse lemurs fed for 5 months on a control diet or on a diet supplemented with long-chain ω3 PUFA (n = 6 per group).

In vivo, ω3 PUFA supplementation lowered the anxiety in tested mice compared to control.

In cognitive parameters assays, ω3-supplementation mouses showed a better performance in a reference spatial memory task (80% of successful trials vs 35% in controls, p<0.05) and reduced spontaneous locomotor activity by 31%.

Importantly, chronic dietary ω3 PUFA supplementation positively impacts anxiety and cognitive performances in the adult mouse lemur.

Based on the findings, researchers said, "The supplementation of human food with ω3 fatty acids may represent a valuable dietary strategy to improve behavioral and cognitive functions".

Taken altogether, Omega-3 fatty acids may be considered a functional supplement for the prevention and treatment of cognitive functions, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 fatty acids from fish oil lower anxiety, improve cognitive functions and reduce spontaneous locomotor activity in a non-human primate by Vinot N1, Jouin M, Lhomme-Duchadeuil A, Guesnet P, Alessandri JM, Aujard F, Pifferi F. (PubMed)

Bioactive Compound Curcumin Found in Herbal Turmeric Inhibits the Risk of Peripheral Arterial Disease In Vitro

By Kyle J. Norton

Peripheral artery disease is a common circulatory condition caused by narrowed arteries that reduce blood flow to your limbs.

Most cases of peripheral artery disease have been associated with the accumulation of plaque in thicking and hardening the arteries, a leading cause of atherosclerosis.

The most common prevalent factors associated with peripheral artery disease are tobacco, physical inactivity, and an unhealthy diet with high in fat, processed food, and red meat and low in fruits and vegetables.

Most patients with peripheral arterial disease are asymptomatic or experience a mild case of pain in the leg while walking. However, as the disease progression, some patients may also experience symptoms of leg numbness or weakness, coldness in their lower leg or foot, sores on their toes, feet or legs that won't heal, a change in the color of their legs, slower growth of your toenails and shiny skin on your legs.

Some men also experience the syndrome of erectile dysfunction in severe cases.

Conventionally, treatment of peripheral arterial disease is focusing improving symptoms, such as leg pain, and quality of life and stopping the progression of atherosclerosis associated with the risk of heart attack and stroke, including medication to lower cholesterol, blood pressure, and blood sugar.

In some cases, surgery may be necessary to treat peripheral artery disease if patients experience claudication that does not respond to medicine.


Some researchers in the investigation of the effect of the heart-healthy diet on peripheral arterial disease wrote, "Peripheral arterial disease (PAD) is a burdensome cardiovascular condition that results from chronic inflammatory insults to the arterial vasculature".


And, "The nutrients reviewed included omega-3 polyunsaturated fatty acids (n-3 PUFAs), folate and B-series vitamins, and anti-oxidants. The diet plans described include the DASH diet, Mediterranean diet, low-fat diet, low carbohydrate diet, Dr. Dean Ornish’s Spectrum® Diet, and Dr. Andrew Weil’s Anti-Inflammatory Diet".

In other words, by changing to a healthy diet with more fruits and vegetables and less red meat, saturated and trans fat, and processed foods peripheral arterial disease may be preventable.


Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.


The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.

On findings of a potential compound for the treatment of heart diseases, researchers examined curcumin treatment improves tissue repair and perfusion recovery in a mouse model of diabetic PAD.

Mice with PAD selected for the study with a normal glycaemic profile treated with curcumin, improved perfusion recovery, observed by the increased capillary density and elevated microRNA (miR)-93 expression in the ischemic muscle tissue.

In vitro, cultured endothelial cells under simulated ischemia, treated with curcumin improved endothelial cell viability and enhanced tube formation.

However, improved endothelial cell viability and enhanced tube formation were inhibited in the presence of the miR-93 inhibitor, regardless of the administration of curcumin.


Based on the findings, researchers said, "curcumin had beneficial effects in non-diabetic PAD by improving angiogenesis, which may have been achieved partially via the promotion of miR-93 expression".

Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of peripheral arterial disease, pending the confirmation of the larger sample size and multicenter human study.


Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose and acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin improves perfusion recovery in experimental peripheral arterial diseaseby upregulating microRNA-93 expression by Zhang J1,2, Wang Q1, Rao G1, Qiu J1, He R. (PubMed)
(2) Advancing Beyond the ‘Heart-Healthy Diet’ for Peripheral Arterial Disease by Emily V. Nosova,1,2 Michael S. Conte,1,3 and S. Marlene Grenon. (PMC)

Omega-3 Fatty Acids Reduce the Risk of Postpartum Depression (PPD)

By Kyle J. Norton

Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, and illness.

Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate. 

Depression may be a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself. 

The mild case of depression can be defeated by a variety of self-care techniques. Others require the treatment of medication, such as antidepressant medications and psychotherapy that help to reduce and sometimes eliminate the symptoms of depression.

Postpartum depression (postnatal depression), is a type of clinical depression, that affects women after childbirth. Normally this nervous tension occurs in women in the first new months of pregnancy, but in some women, it can last after childbirth. 

The rate of occurrence is between 5 -25%, depending on the uniqueness of each woman. In men, the occurrence of postpartum depression is uncleared, affecting between 1% and 25%.

Normally the symptoms will go away on their own in a short period of time (Baby blue symptoms). In some women, the symptoms get more serve every day and do not go away which can lead to the onset of postpartum depression.

Since postpartum depression is a serious mental illness, it can interfere with your ability to look after yourself, your child, and your daily activities performance, etc.

If left untreated, it can badly affect your newborn such as loving one minute and being withdrawn the next, do not respond to the needs of the baby, leading to the insecurity attachment(a negative feeling when they are baby), lack of emotional bond between the mother and the baby, etc

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical that processed anti-psychological activity researchers examined and compared the effects of omega-3 polyunsaturated fatty acid supplementation on depression during pregnancy or postpartum depression (PPD) after childbirth.

The study included a search of medical literature published on MEDLINE, PubMed, PsycINFO, and the Cochrane Collaboration Registry of Controlled Trials, etc. through July 2017.

According to the identified studies, omega-3 fatty acid deficiency, due to inadequate intake, and fast depletion during pregnancy and lactation were associated with one of the risk factors of PPD.

Additionally, the elevated neuroinflammation (elevated pro-inflammatory cytokines) and aberrant neurotransmission (low serotonergic transmission activity) also increased the risk of PPD.

Supplementation with eicosapentaenoic acid (EPA)-rich oil showed effectively reduces depression during pregnancy and PPD after childbirth. 

However, long-term treatment with docosahexaenoic acid (DHA)-rich oil could also be effective in reducing the risk of PPD in healthy women, but not in lactating women.

Moreover, Supplementation of DHA-rich oil to women begun at pregnancy and continued after childbirth showed no beneficial effect on depression.

Based on the evidence, researchers wrote, "Dietary supplementation with omega-3 fatty acids rich in EPA during pregnancy or postpartum reduces some symptoms associated with depression. DHA supplementation to healthy pregnant women can also reduce the risk of PPD".

Taken altogether, Omega-3 fatty acids may be considered functional foods for the prevention of postpartum depression (PPD), pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 polyunsaturated fatty acid supplementation in prevention and treatment of maternal depression: Putative mechanism and recommendation by Hsu MC1, Tung CY2, Chen HE. (PubMed)

Beta-Sitosterol Found in Japanese Arrowroot or Chinese Arrowroot Shows an Effect on Menopausal Symptoms In Vivo

By Kyle J. Norton

Menopause is a condition in which a woman is in the transition stage of permanent cessation of the ovary's functions in egg production because of less production of estrogen and progesterone, signaling the end of the reproductive phase of a woman's life.

In menopause, menstruation has become irregular and slowly stops over time, but in some women, menstrual flow comes to a sudden halt.

Some researchers suggested that you officially enter the stage of menopause if you have gone 12 months without a menstrual period.

Compared to menopause, peri-menopause is a condition in which women experience an irregular menstrual cycle due to the hormonal decline gradually, including shorter, longer, heavy, light periods and some menopause symptoms.

Perimenopause, in fact, is a transition stage to menopause, and the length of this transition can be 3-10 years or longer. Once you have no menstrual period in 12 consecutive months, you have officially entered 12 months of menopause already.


Women enter the menopause stage differently, but the average age is 51 in the United States.

Women with ovarian failure or removed may experience symptoms of menopause at the early age of 38.

Symptoms of menopause are the result of the gradually reduced production of estrogen and progesterone, the 2 most abundant hormones in childbearing-age women.

Most women in the Western world experience symptoms of hot flashes and emotional symptoms of menopause may disrupt your sleep, lower your energy or affect emotional health.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.

In finding a potential phytochemical for the treatment of menopausal symptoms, researchers elucidated the biological activities of Pueraria lobata (PL) on menopause-related metabolic diseases.

According to the results of ovariectomized (OVX) rats as a postmenopausal model that was administered PL at different doses (50, 100, and 200 mg/kg),* The decreased uterine weights and PPAR-γ (peroxisome proliferator-activated receptor-gamma) mRNA expression in the thigh muscle found in menopausal females in the ovariectomized (OVX) rats were significantly recovered after PL administration.

* Furthermore, PL also significantly alleviated OVX-induced increases in total cholesterol, triglyceride, alanine aminotransferase (ALT/GPT), and aspartate aminotransferase (AST/GOT) levels.

More precisely, the efficacy of Pueraria lobata (PL) on menopause-related metabolic diseases was attributed to four potential active compounds, including beta-sitosterol.

In other words, the chemical compounds exerted a strong activity against multiple targets among female sex hormone-related pathways, including the estrogen signaling pathways, progesterone-mediated oocyte maturation, oxytocin signaling pathways, and prolactin signaling pathways.

Based on the findings, researchers said, "PL improved various indicators associated with lipid metabolism in the postmenopausal animal model".


Beta-Sitosterol may be considered a remedy for the prevention and treatment of menopausal symptoms, pending the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Investigating the Systems-Level Effect of Pueraria lobata for Menopause-Related Metabolic Diseases Using an Ovariectomized Rat Model and Network Pharmacological Analysis by Oh JH1, Baek SE2, Lee WY1, Baek JY3,4, Trinh TA3, Park DH3, Lee HL5, Kang KS3, Kim CE1, Yoo JE. (PubMed)

Tocopherols Inhibits The Liver Oxidative Stress

By Kyle J. Norton

Oxidative stress is a condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.

In other words, oxidative stress is either caused by overexpression of free radicals or depletion of antioxidant enzymes in the body.

Some researchers suggested that oxidative stress may also arise due to the chain reaction of free radicals in which free radicals donate or intercept an electron from other stable molecules.

Long-term oxidative stress present in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including cardiovascular disease, diabetes, and cancer.

In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.

There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, and oxidative burst from activated macrophages, particularly, the free radicals chain reaction.

Sadly, a prolonged period of oxidative stress present in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.

Certain chronic diseases are found to be associated with oxidative stress, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, seed or nut oils, etc.

On finding a potential phytochemical for the treatment of diseases associated with oxidative stress, researchers examined the curative efficacy of L-Ascorbic acid (L-AA) and α-Tocopherol (α-TOC) against Arsenic trioxide (As2O3) toxicity using immortalized human Chang liver cells.

According to the analysis,
* L-AA (100 µM) and α-TOC (50 µM) recovered As2O3 (10 µM) cytotoxicity.

* As2O3 treatment showed an increase in lipid peroxidation and depletion in antioxidant status, mitochondrial transmembrane potential, and values of total antioxidant capacity.

* Cotreatment of antioxidant vitamins with As2O3 resulted in a significant reversal of oxidative stress markers.

Based on the results, researchers said, "substantiate the effect of antioxidant vitamins in protecting the hepatocytes from oxidative stress which may be attributed through Nrf2 (Nuclear factor erythroid 2-related factor 2) mediated upregulation of Bcl2 (B-cell lymphoma 2) expression".

Taken altogether, tocopherols may be considered a supplement for reducing the risk of liver oxidative stress, pending the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) L-Ascorbic Acid and α-Tocopherol Reduces Hepatotoxicity Associated with Arsenic Trioxide Chemotherapy by Modulating Nrf2 and Bcl2 Transcription Factors in Chang liver Cells by Vineetha RC1, Archana V1, Binu P1, Arathi P1, Nair RH. (PubMed)

Maternal Coffee and Coffee Caffeine Intakes May Increase the Risk of Poor Child Cognition and Behavior, Researchers Say

By Kyle J. Norton

Food therapy is a slowly recovering but effective method used in traditional medicine to ease symptoms and treatment of diseases, depending on the stages of the treatment which directly addresses the roots of the cause without inducing adverse effects.

Epidemiological studies do not agree that coffee and coffee caffeine intake during pregnancy may have a negative impact on child cognition and behavior.

Coffee, second to green tea is a popular and social beverage all over the world, particularly in the West, made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.

Caffeine, a chemical stimulant found abundantly in caffeinated products, including tea and coffee is a class of methylxanthine having a profound impact on the central nervous system (CNS).

Cognition and Behavior is a group of neuro functions involving sensation and perception, learning and memory, attention, mental imagery, conceptual presentation, language expression, emotion response, and motor control,.....

In the study of examining maternal serum paraxanthine at <20 and ≥26 weeks' gestation with the child's intelligence quotient (IQ) and problem behaviors at ages 4 and 7 years among 2,197 mother-child pairs, researchers showed that paraxanthine, a structurally related to caffeine.and caffeine's primary metabolite concentration has a significantly inverted effect at ≥26 weeks' gestation with child's IQ at age 7 years.

And at <20 weeks, paraxanthine also expressed a linearly associated with internalizing behavior at age 4 years.

Paraxanthine is a caffeine metabolite and central nervous system (CNS) stimulant processed a similar potency equal to that of caffeine.

Interestingly, after taking into account a range of values applicable to most pregnant women, researchers indicated that coffee caffeine in contribution to serum paraxanthine concentration showed no significant effect in association with childhood IQ or problem behaviors.

In contrast to the healthy mothers, women's reported coffee intake per day during pregnancy was associated with a lower child's behavior rating scale (BRS), a complete overview of child and adolescent concerns and disorders, and ratings in anemic children. Even with the inclusion of other contributing factors and after anemic children were given appropriate treatment, coffee consumption continuously showed poor child cognition and behavior.

The Behavior Rating Scale (BRS) is an assessment frequently used by experts in the assessment of the development of child cognition and behavior in infants and children, including autism.

Dr.Engle PL, the lead author said, " The effects of postnatal coffee ingestion in Guatemala were seen for sleep duration, but not for cognitive development. Prenatal coffee ingestion was negatively associated with behavior rating scales".

Taking all together, coffee caffeine intake during pregnancy may not have any meaningful effect in association with children's cognitive development and measurement by behavior rating scales, excluding anemic children. But caffeine as a neural stimulant may have a negative impact on the brain function by altering fetal normal neural transmission during a stage of brain development, some researchers are concerned.

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age by Klebanoff MA, Keim SA.(PubMed)
(2) Effects of discontinuing coffee intake on iron-deficient Guatemalan toddlers' cognitive development and sleep by Engle PL1, VasDias T, Howard I, Romero-Abal ME, Quan de Serrano J, Bulux J, Solomons NW, Dewey KG.(PubMed)

Beta-Sitosterol Processes Hypolipidemic Activity

By Kyle J. Norton

The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.

The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.

Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.

Cholesterol found in our body is needed to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques built up on the arterial wall, the major cause of heart disease and stroke.

More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.

High blood cholesterol is the most common cause of hyperlipidemia. According to statistics provided by the CDC, more than 12% of adults age 20 and older are living with high blood cholesterol with a total cholesterol higher than 240 mg/dL. and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.

In other words, hyperlipidemia has a high prevalent ratio that affects over 100 million American and the condition is increasing at an alarming rate due to overweight and obesity.

Believe it or not, only half of the people with high blood cholesterol benefits from taking the lowering blood cholesterol medicine.

People with hyperlipidemia are asymptomatic. However, if untreated, the condition can cause cholesterol build-up on the arterial wall, leading to narrowing the arteries inducing blockage that causes heart disease and stroke.

The most common inherited form of high blood cholesterol is called familial hypercholesterolemia found in 1/500 people.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention of diseases involved in high blood cholesterol, researchers investigated β-sitosterol ester with linoleic acids and β-sitosterol self-microemulsions preparation on hyperlipidemia mice.

Selected mice were randomly divided into normal group and model group, fed with a basic diet and high-fat diet for 70 days respectively. 

After high-fat model mice were successfully established, the model group was further divided into eight groups: HFD (high-fat diet feeding), SELA-TSO(8 ml/kg, SELA:700 mg/kg), TSO (8 ml/kg), SSSM (8 ml/kg,SS:700 mg/kg), NLSM (8 ml/kg), SSHT-TSO (8 ml/kg, SS: 700 mg/kg) and SS-TSO (8 ml/kg, SS: 700 mg/kg) groups, and treated with β-sitosterol ester with linoleic acid, β-sitosterol self-microemulsion, commercial β-sitosterol health tablets, and β-sitosterol powder for 35 days, respectively.

Based on the results of the experiment,

* β-sitosterol self-microemulsion has the highest anti-hyperlipidemic effect among the experimental groups, compared to β-sitosterol ester with linoleic acids.

* The anti-hyperlipidemic effects are listed as SSSM> SELA-TSO > SSHT-TSO > SS-TSO.

Collectively, researchers said, "a new formulation of β-sitosterol was developed, and its hypolipidemic effect was investigated. The results showed that β-sitosterol self-microemulsion has a good blood lipid-lowering effect".

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of hyperlipidemia, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effect of β-sitosterol self-microemulsion and β-sitosterol ester with linoleic acid on lipid-lowering in hyperlipidemic mice by Yuan C1, Zhang X1, Long X1, Jin J1, Jin R. (PubMed)