Beta-Sitosterol Suppresses the Cervical Cancer Initiation

By Kyle J. Norton

Cancer is a class of chronic diseases associated with irregular cell growth in the tissues of the affected organ.

Cervical cancer is a malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cells DNA.

The cervix is the lower part of the uterus that opens at the top of the vagina. The cervix acts as a transition area for the vaginal lining.

Most cases of cervical cancer start in the cell on the surface of the inner lining tissue of the cervix. At this stage, most women with cervical cancer do not experience any symptoms.

At the advanced stage, invasive cancer can induce symptoms of abnormal bleeding, pain during sexual intercourse, increased vaginal discharge. If the tumor has suppressed the nearby nerve cells, cervical cancer can also cause localized severe pain.

According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer were diagnosed with the death of 4,020 patients.

The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites.

Other risk factors associated with cervical cancer are  HPV infection, sexual activity, smoking, giving birth many times, infection with the human immunodeficiency virus (HIV, history of sexually transmitted infections (STIs) and long-term use of oral contraceptives/

However, most women with some of the risk factors have never developed cervical cancer.

According to the statistic, the 5-year survival rate for women with invasive cervical cancer is 92%. and approximately, 46% of women with cervical cancer are diagnosed at an early stage.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of cancer, researchers examined the effects of β -sitosterol, a natural product isolated from traditional Chinese herbs, on Caski and HeLa cervical carcinoma cells.

According to the experimental analysis, the application of β-sitosterol on Caski and HeLa cells showed an inhibitory effect on cell proliferation by reducing the expression of PCNA associated with antigens in cell cycle division.

The increased expression of p53 that suppressed the levels of tumor cells mRNA levels and decreased amounts of HPV E6 transcripts produced by the tumor cells were also found in the β-sitosterol treatment of Caski and HeLa cells. 

Furthermore, the treatment of Caski and HeLa cells also exhibited tumor cell apoptosis by inducing the loss of cell surface microvilli, increased electron density of cell membranes, and decreased organelles.

Based on the evidence, researchers said, "treatment of Caski and HeLa cells with β-sitosterol significantly suppressed the expression of genes involved in cell proliferation and oncogenic transformation, while augmenting the expression of genes involved in apoptosis and tumor suppression".

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of cervical cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effect of β-sitosterol on the expression of HPV E6 and p53 in cervical carcinoma cells by Cheng D1, Guo Z1, Zhang S. (PubMed)

Broccoli's Sulforaphane Supplementation Has No Effects on Neutrophilic Airway Inflammation

By Kyle J. Norton

Respiratory Disease is medical conditions, that affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc.


Acute inflammation is a natural response of the immune system to protect the human body against harmful stimuli and pathogens.

Acute information is the first phase of injection. At this phase, after sensing the body injury by the central nerves system, the immune first line of defense stimulates the production of blood platelets to the cover the site of damage and pro-inflammatory to kill off pathogens that try to enter the body through the wound or damaged tissue.

Acute inflammation usually receded after a few days or weeks depending on the size and damage. However, if all pathogens were not eradicated after 3 to 8 weeks, the immune system will compromise, leading to chronic low-grade inflammation, a leading cause of chronic illness.

The most common symptoms of acute inflammation occurred with a short period of time such as hours is pain, redness, immobility, swelling, and heat.

Conventionally, depending on the types of acute inflammation, non-steroidal anti-inflammatory drugs (NSAIDs) may be prescribed to alleviate the pain by counteracting an enzyme that contributes to inflammation.

Asthma is a chronic inflammatory disease affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. 

The disease affects people of all ages, and mostly starts during childhood. In the study of 463,801 children aged 13-14 years in 155 collaborating centers in 56 countries.

Neutrophilic airway inflammation in asthma is a complication associated with the whole spectrum of asthma severity, ranging from mild-to-moderate to severe uncontrolled disease, compared to neutrophilic inflammation that occurs mostly in more severe asthma.

Broccoli is a mustard/cabbage plant, belong to the family Brassicaceae. The veggie has large flower heads, usually green in color and the mass of flower heads surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

On finding a potential plant that protects the lung activity, researchers examined the effects of sulforaphane (SFN), a naturally occurring isothiocyanate found in cruciferous vegetables on neutrophilic airway inflammation.

The study included male rats that were divided into the control group fed the AIN-76 diet, and the BSEx group fed the AIN-76 diet containing BSEx for 10-days.

On airway inflammation via induction of the transcription factor NF-E2-related factor 2 (NRF2), supplementation of SFN with broccoli sprout homogenate did not induce the expression of antioxidant genes in healthy human subjects.

In an ozone-exposure model, the supplementation showed no effects in the protection against neutrophilic airway inflammation.

In other words, dietary sulforaphane supplementation did not promote the production of antioxidant enzymes in the tested model through its anti-inflammatory activity

Based on the finding, researchers said, "supplementation of SFN with broccoli sprout homogenate is not a promising candidate for large-scale clinical trials targeting airway inflammation".

Taken altogether,  broccoli may be considered liver detoxed functional food, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation by Duran CG1, Burbank AJ1, Mills KH1, Duckworth HR1, Aleman MM1, Kesic MJ2, Peden DB1, Pan Y3, Zhou H3, Hernandez ML. (PubMed)

Beta-Sitosterol, the Anti-Inflammatory Phytochemical

By Kyle J. Norton

Inflammation is a natural response by the immune system to protect the body against the invasion of stimuli or foreign pathogens.

Acute inflammation is a short-term condition caused by tissue injury, leading to pain, redness, swelling, and heat to the affected area, depending on the size of the injury. Some patients with acute inflammation may also experience the symptom of loss of function.

In acute inflammation, the white blood cells on the first line of defense of the immune system after sensing the danger of an infection in the body through a message from the brain stimulate the production of platelets to cover the site of injury or damage and inflammatory cytokines to kill off all pathogens before they can cause harm to the body.

Most cases of infection are stopped at the acute phase. The wound or injury is slowly recovered.

Chronic inflammation is a low-grade inflammation caused by the inability of the immune system to eliminate the invasive pathogens that occurred in the acute phase of infection.

Any inflammation that lasts more than 8 weeks is considered chronic inflammation.

Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.

Anti-inflammation is the process that inhibits inflammation or swelling without affecting the immune property to curb foreign pathogens.

Conventionally, the most common use of anti-inflammatory medicines is over counter aspirin, ibuprofen (Advil, Motrin, Nuprin) and other prescription NSAIDs.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention of diseases involved in oxidative stress, researchers investigated the anti-inflammatory activity of β-sitosterol (BSS) isolated from Moringa oleifera in two cell lines.

According to the experimental analysis, over a dose range of 7.5 to 30 μM, BSS in the medium as nanoparticles with diameters of 50 ± 5 nm suppressed the secretion of inflammatory factors from keratinocytes and macrophages induced by ROS and proteins associated with the production of pro-inflammatory cytokines such as TNF-α, IL-1β, IL-6, IL-8, 

The application of BSS significantly reduced the expression of NLRP3, a key component of NLRP3 inflammasomes that participates in the production of the pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18, and inhibited the activation of caspase-1, the precursors of the inflammatory cytokines interleukin 1β and interleukin 18.

NF-κB, the protein associated with the signaling of inflammation in macrophages was also partially inhibited by BSS.

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of inflammation, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Identification of β-Sitosterol as in Vitro Anti-Inflammatory Constituent in Moringa oleifera by Liao PC1, Lai MH2, Hsu KP3, Kuo YH4, Chen J1, Tsai MC5, Li CX6, Yin XJ6, Jeyashoke N7, Chao LK. (PubMed)

Cranberry, the Antioxidants Functional Fruit

By Kyle J. Norton

Free radicals are highly unstable atoms. Internally, free radicals are produced by our body cell metabolism. Externally, free radical can enter our body from the environment sources, such as the air we breathe, the food we eat and the water we drink.

In other words, any chemicals compounds or molecules which process an oxygen atom can be free radicals in a chemical reaction with other atoms.

According to epidemiological studies, free radicals are dangerous to human health in excessive amounts. Overexpression of free radicals induced oxidative stress has been found to damage the lipid, and protein and induce the alternation of healthy cell DNA.

Antioxidants are stable atoms that inhibit oxidation induced by free radicals.

Out of all damages caused by overexpression of free radicals, some researchers suggested that lipid peroxidation induced by free radicals has a strong implication in the pathogenesis of various disorders and diseases.

Oxidative stress can either be caused by overexpression of free radicals or depletion of antioxidant enzymes produced by the host. The condition has been found to induce cardiovascular disease and type 2 diabetes.

In a healthy person, antioxidants produced by the body are more than enough to counter the expression of free radicals. However, in people with a weakened immune system, the intake of dietary antioxidants regularly can be helpful.

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia.

 Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the treatment of diseases associated with oxidative stress, researchers examined the effect of cranberry (V. macrocarpon) antioxidant activity.

According to studies, 

* Vaccinium oxycoccos fruit as a whole group is a valuable source of antioxidants and other biologically active substances.

* European cranberry fruit processed a strong antioxidant property due to rich in polyphenolic compounds anthocyanins (12.4–207.3 mg/100 g fw), proanthocyanins (1.5–5.3 mg/100 g fw), and flavonols, especially quercetin (0.52–15.4 mg/100 g fw).

* Small cranberry showed a significant antioxidant effect against various biological protection including urinary tract protection (proanthocyanidins), antibacterial and antifungal properties (quercetin, proanthocyanidins, anthocyanins), cardioprotective (proanthocyanidins) and anticancer activities (proanthocyanidins).

Based on the findings, researchers said, "Taking into account various beneficial effects of small cranberries on human health, also in folk medicine, the consumption of these fruits and their products is widely recommended.".

Taken altogether, cranberry may be considered a remedy for the enhancing antioxidant activity, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Bioactive Compounds, Antioxidant Activity, and Biological Effects of European Cranberry (Vaccinium oxycoccos) by Tunde Jurikova,1 Sona Skrovankova,2 Jiri Mlcek,2,* Stefan Balla,1 and Lukas Snopek. (PMC)

Cabbage Kills Pancreatic Cancer Cells in Vitro

By Kyle J. Norton

The pancreas is an oblong flattened gland in the digestive and endocrine system located in the abdomen.

By secreting pancreatic juice to the small intestine, the pancreas breaks down carbohydrates, proteins, and lipids. Traditional Chinese medicine views the pancreas as a vital organ that is responsible for the absorption of foods' qi and nutrients before passing them to other organs to nourish our bodies.

The pancreas plays a major role in regulating blood glucose levels by producing insulin.

Type 1 diabetes occurs when the pancreas does not make enough or any insulin. Type 2 diabetes develops when the body cannot use insulin correctly.

Pancreatic cancer is a chronic condition characterized by cell growth irregularly in the tissues of the pancreas.

According to statistics, every year, approximately, over 55,000 adults in the United States are diagnosed with pancreatic cancer, accounting for 3% of all cancers and 7% of all cancer deaths.

The survival rate of pancreatic cancer even diagnosed early is very low compared to other types of cancer. The 5-year survival rate at stage IA pancreatic cancer is only14%.

The most common risk factors of pancreatic cancer are similar to those of common cancers, including age, family history, gender, ethnicity, smoking, being overweight or obesity and certain medical conditions such as diabetes.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.

With an aim to find natural food in the prevention and treatment of tumors, researchers investigated the anticancer effects of kimchi prepared by the standard Baechu cabbage and Amtak Baechu cabbage.

4 different kimchi samples that were prepared for this study: (1) the standard Baechu cabbage and dry salt treatment method (SK-D); (2) the Amtak Baechu cabbage and dry salt treatment method (AK-D); (3) the standard Baechu cabbage and brine solution treatment method (SK-B); and (4) the Amtak Baechu cabbage and brine solution treatment method (AK-B).

In human pancreas cancer cells (Capan-2) and human liver cancer cells (HepG2), both cancer cells exposed to AK-D and AK-B showed a significant increase in cell growth inhibition, compared yo SK-D and SK-B (p < 0.05).

At 2.0 mg/mL, the inhibition of Capan-2 cells was more than doubled after treatment with AK-B and AK-D compared with SK-B and SK-D, but was only 1.2 times in HepG2 cells.

AK-D and AK-B treatment exhibited apoptosis and cell cycle arrest by a significant increase of p21 levels associated with cell cycle regulation.

AK-B exerted a higher cytotoxic activity compared with AK-D and the anticancer effects were more apparent in Capan-2 cells than in the HepG2 cells.

Based on the results, researchers wrote, "...kimchi made with Amtak Baechu cabbage and treated with brine solution (AK-B) had a superior anticancer potential against both types of cancer cells, with the effects being greater in pancreatic cancer cells compared with liver cancer cells".

Taken altogether, kimchi made with Amtak Baechu cabbage may be used for the prevention and treatment of pancreatic cancer, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Beneficial Outcomes of Kimchi Prepared with Amtak Baechu Cabbage and Salting in Brine Solution: Anticancer Effects in Pancreatic and Hepatic Cancer Cells by Song GH1, Park ES1, Lee SM1, Park DB2, Park KY. (PubMed)

Common Fig or Fig Kills the Melanoma Cells in Vitro

By Kyle J. Norton

Skin is the largest organ in the body with function to protect the internal organs and tissues against foreign organisms infection, leading organs and tissue injury and damage.

It also is the third organ behind the liver and kidney to eliminate body toxins if the first 2 fails to cleanse them all.

What are the exact causes of skin damage? Some researchers suggested that long-term exposure to the sun is the most common cause of skin damage. UV rays can damage the DNA of skin cells, affecting the normal skin cell growth. UV rays have been linked to the early onset of skin cancer, epidemiologically.

Skin melanoma is a skin cancer characterized by the alternation of the pigment-containing cells known as melanocytes. However, in rare cases, melanoma can also occur in the mouth, intestines, or eye.

The 4 most common types of skin melanoma include
* Superficial spreading melanoma, the type of cancer has a tendency to spread grow outward and spread across the surface of the skin, accounted for 70% of all melanoma skin cancer.

* Nodular melanoma normally grows down into the skin and has a tendency to spread more quickly than other types of melanoma skin cancer.

* Lentigo malignant melanoma, most common in the older population, making up approximately 15% of all melanoma skin cancer.

* Acral lentiginous melanoma, most common in people with darker skin. Cancer first moves outward before spreading deeper into the skin.

The causes of melanoma skin cancer are associated with the alternation of the pigment cells in the skin.

However, according to the epidemiological studies, genetic mutation inherited from the parent, exposure to the environmental toxins and sun UV rays are the most common causes associated with the increased risk of melanoma skin cancer.

According to the statistic, melanoma skin cancer is increasing and anticipated to continue to rise. In the United States, approximately 70,230 new cases of melanoma were diagnosed, causing the death of 8,790.

Fig is a species of F. Carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.

On finding natural compounds for the treatment of skin diseases, researchers examined the latex of fig fruit (Ficus carica) free radical-scavenging activity on 1,1-diphenyl-2 picrylhydrazyl (DPPH) and its phototoxicity on A375 human melanoma cells.

According to the tested differentiation.
* The latex obtained from the fruits of Ficus carica cv. Dottato showed the best antiradical activity with an IC50 value of 0.05 mg/ml

* Furthermore, the latex obtained from the leaves demonstrated the best antiproliferative activity with an IC50 value of 1.5 μg/ml on the human tumor cell line A375 (melanoma) after irradiation at a specific UVA dose (1.08 J/cm2).

* More importantly, the application exerted no cytotoxic effect on healthy control cells.

Based on the findings, researchers said, "comparing F. carica latex of leaves and fruits,... Plant-derived natural products have long been and will continue to be an important source for anticancer drug development".

Taken altogether, common fig or fig (Ficus carica)  may be considered anti-melanoma remedy, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Fig latex (Ficus carica L. cultivar Dottato) in combination with UV irradiation decreases the viability of A375 melanoma cells in vitro by Menichini G1, Alfano C, Provenzano E, Marrelli M, Statti GA, Somma F, Menichini F, Conforti F. (PubMed)

Tocopherols, A Promising Phytochemical for the Treatment of Asthma

By Kyle J. Norton

Respiratory Disease is a class of medical conditions that affect the breathing organ and tissues including inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc.

The lungs formed part of the respiratory system are a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream to nourish the body cells need and exhaling carbon dioxide from the bloodstream.

Additionally, the lung is also the first-line defense against inhaled particles and prevent the circulation of emboli such as blood clot (thrombus), a fat globule (fat embolism), a bubble of air or other gas (gas embolism), or foreign material.

Asthma is a chronic inflammatory disease affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing.

The disease affects people of all ages, and mostly starts during childhood.

During the asthma attacks, patients may experience symptoms of difficult breathing, and severe wheezing in the breath and coughs that won't stop.

According to the statistic provided by the Centers for Disease Control and Prevention (CDC), 1 in 13 people in the US has asthma.

In other words, more than 26 million Americans have asthma, with half of the patients are children.

If you experience symptoms of a cough which often worse at night or early in the morning, wheezing in your breath, accompanied by chest tightness and shortness of breath, you may be at the early stage of asthma. Please check with your doctor to rule out the possibility.

Genetic and environmental factors are the most common risk factors associated with the onset of asthma. Some researchers suggested that the widespread obesity over the past few decades may also have a strong implication on the onset of the disease.

Tocopherols are phytochemicals of which many have vitamin E activity, belongings to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of chronic lung diseases, researchers examined the effects of γ-tocopherols, a specific form of vitamin E, on asthma remission.

According to the analysis,
* γ-tocopherols possesses the capability to reduce the number of eosinophils associated with the immune response against allergy.

* γ-tocopherols inhibited the production of pro-inflammatory cytokines induced by the immune response by exudation of inflammatory cells together with the hyperplasia of goblet cells.

* γ-tocopherols also reduced the high levels of eotaxin, eosinophil chemotactic protein, and IL-4, proinflammatory cytokine in the asthma group comparable with hexadecadrol.

After talking about other factors into account, researchers said, "γ-tocopherols can remit asthma by regulating the level of eotaxin and IL-4. Moreover, γ-tocopherols may be regarded as a potential candidate for asthma treatment after much deeper explorations".

Taken altogether, tocopherols may be considered adjunct therapies in the treatment of asthma, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Comparable Function of γ-Tocopherols in Asthma Remission by Affecting Eotaxin and IL-4 by Wu YM1, Xue ZW1, Zhang LL1, Gao NM1, Du XM1, Zhang XY1, Zhang ZH1, Zhang ZG. (PubMed)
(2) Serum carotenoid and tocopherol concentrations and risk of asthma in childhood: a nested case-control study by Hämäläinen N1, Nwaru BI1,2, Erlund I3, Takkinen HM1,4, Ahonen S1,5,6, Toppari J7,8, Ilonen J9,10, Veijola R11, Knip M12,13,14, Kaila M15,16, Virtanen SM. (PubMed)