Omega 3 Fatty Acid Reduces the Risk of Hypertension

By Kyle J. Norton

Hypertension is a condition characterized by persistent high blood pressure.

According to the American Heart Association (AHA) patients with blood pressure that higher than 130 over 80 millimeters of mercury (mmHg) is considered to have hypertension.

In the US approximately, one-third of the adults have hypertension, affecting over 77 million people in the country.

Additionally, among adults age 20 and older in the United States, in the non-Hispanic whites community, 33.4 percent of men and 30.7 percent of women are infected by the syndrome.

Hypertension is a slowly developed condition. Unless the syndrome has caused damage to the blood vessel, otherwise symptoms cannot be detected.

The cause of hypertension is a result of hardening and thickening of the arteries (atherosclerosis), due to the slow progression of plaques accumulated on the wall of the arteries.

Some researchers suggested that unhealthy dietary and lifestyle factors highlight the importance of environmental factors in the induction of hypertension onset and progression(4).

However, according to a special issue of the Journal of Human Hypertension primarily, in the concerns of dietary, lifestyle and alternative factors in the risk of hypertension and blood pressure control, focus on dietary and lifestyle factors, complementary and alternative approaches may have a strong impact in prevention and treatment of hypertension.

Therefore, increased physical activity and diet rich in fruits, vegetables, and low-fat dairy products, along with a reduction in saturated and total fat may be the best choice in exerted protective effects on blood pressure.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of heart diseases, researchers examined the Omega 3 fatty acid activity on blood pressure (BP).

In the prospective cohort study based on the data on 12 279 PHS participants (mean age: 53.0 ± 8.7 years) free of hypertension at baseline, during a mean follow-up of 15.8 years,

According to the results of the study of the fish and omega-3 fatty acid consumption assessed from a baseline semiquantitative food-frequency questionnaire,

* Fish and omega-3 fatty acid consumption was not significantly associated with incident hypertension.
* The hazard ratio (95% CI) of hypertension was 1.10 (0.93-1.30) for men who consumed at least five servings per week of fish compared with those who did not consume any fish (P for trend = 0.29).

* For the highest versus lowest quintile of omega-3 fatty acid intake, the hazard ratio of hypertension was 1.02 (0.94-1.11) (P for trend = 0.34).

* The associations did not vary by type of fish. There was also no evidence of effect modification by baseline BP, BMI, or history of hypercholesterolemia.

Moreover, researchers said, "Overall, long-term dietary intake of fish and omega-3 fatty acid was not associated with incident hypertension in a cohort of middle-aged and older US men".

Taken altogether, Omega-3 fatty acids may be considered a functional food for the prevention and of hypertension, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Fish and omega-3 fatty acid consumption and risk of hypertension by Matsumoto C1,2, Yoruk A3, Wang L4, Gaziano JM1,4,5, Sesso HD. (PubMed)

Herbal Angelica Promotes the Immunomodulatory Activity

By Kyle J. Norton

The immune system is the set of cells that comprise the body's defense system against diseases against antigens or infectious agents

Immunomodulatory activity is an action that improves the underactive immune function that is susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.

The overactive immune system is a class of autoimmune diseases or chronic inflammatory diseases caused by the immune system attacking the body's tissue, including rheumatoid arthritis (RA), rheumatoid arthritis, systemic lupus erythematosus,.... and multiple sclerosis.

The widespread chronic inflammatory diseases in modern society are a burden to humans because of life-long debilitating illness, increased mortality and high costs for therapy and care.

On the other hand, an underactive or weakened immune system caused by a primary immune deficiency or acquired immune deficiency.may not protect the body against foreign organisms in initiated infection. 

Primary immune deficiency is an underactive immune system that is caused by genetic mutation inherited from parents.

Acquired immune deficiency is a weakened immune system caused by diseases that destroy white blood cells.

In other words, the immunomodulatory activity involved antimicrobial agents is to modulate the genes involved in immune reactions, or of the neurohormonal system which regulates immune functions and any toxic or immunotoxic effects such as allergic reactions or destruction of immune effectors, that may cause harm to the body or interfere with the body normal function.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a potential herbal medicine to improve the immune functioning, researchers examined the immunomodulatory activity of four fractions of angelica (Angelica polysaccharide, oligosaccharides (Angelica oligosaccharide and Angelica sucrose) and Angelica total amino acid, named APS, AOS, AS, and TAA on murine peritoneal macrophages.

Based on the results of the analysis, Although APS exhibited the most obvious growth facilitative activity, AOS did better in the activation of H(2)O(2) release.

TAA exerted the best activation of phagocytic activity, production of NO and ICAM-1 expression.

Furthermore, the action mode of the four fractions was similar to that of LPS and the mechanism may be related to the upregulation of TLR4 mRNA. in the regulation of the immune response.

These results demonstrated that all 4 tested fractions isolated from the Radix A. Sinensis, could serve as an immunomodulator for the improvement of the immune functioning.

Taken altogether, Herbal Angelica processes immunomodulatory activity, pending to larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Assessment and comparison of immunoregulatory activity of four hydrosoluble fractions of Angelica sinensisin vitro on the peritoneal macrophages in ICR mice by Chen Y1, Duan JA, Qian D, Guo J, Song B, Yang M. (PubMed)

Broccoli Inhibits the Pancreatic Cancer Cells in Vitro

By Kyle J. Norton


Pancreatic cancer is a chronic condition characterized by cell growth irregularly in the tissues of the pancreas.

Most cases of primary pancreatic cancer start in the cell on the surface of the inner lining of the pancreatic tissue, before penetrating into the deeper layers to form a large and invasive tumor.

At the early stage, patients with pancreatic cancer may be asymptomatic. However, at the later stage, besides the common symptoms shared by all types of cancer such as unintended weight loss, loss of appetite, fatigue and gastrointestinal discomforts, patients with the condition may also experience localized symptoms such as internal bleeding and severe pain due to the oversize tumor which suppresses the nerve cells and blood vessels.

According to statistics, every year, approximately, over 55,000 adults in the United States are diagnosed with pancreatic cancer, accounting for 3% of all cancers and 7% of all cancer deaths.

The survival rate of pancreatic cancer even diagnosed at a very early stage is very low compared to other types of cancer. The 5-year survival rate at stage IA pancreatic cancer is only14%.

Scientists do not know the exact causes of pancreatic cancers, but they do know several risk factors that can make a person more likely to get the disease, including the genetic and acquired genetic mutation of p16 and TP53 and KRAS, BRAF, and DPC4 (SMAD4).

Other prevalent risk factors, including long-term use of tobacco, exposure to certain chemicals, overweight, and obesity, and unpreventable risk factors of family history, gender, the increase of age and ethnicity are associated with the early onset of pancreatic cancer.

The secondary pancreas cancer has been found to be a metastasis from renal cell cancer, lung, colon and breast cancers.

Broccoli is a mustard/cabbage plant, belong to the family Brassicaceae. The veggie has large flower heads, usually green in color and the mass of flower heads surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

On finding a potential plant that processes anticarcinogenic activity, researchers examined the effects of sulforaphane (SF) on the pancreatic cancer cell lines.

In established cell lines and a patient tissue array (n = 96), sulforaphane inhibited the expression of miR30a-3p in the induction of cancer cell lines.

Furthermore, miR30a-3p mimics inhibited the luciferase activity of a Cx43 3'-UTR, a tumor suppression.

Moreover, miR30a-3p-overexpressing tumor xenografts had decreased tumor volume and increased gemcitabine sensitivity in pancreatic cell lines.

The study included 16 subjects randomized, into 3-phase crossover dietary trial of standard broccoli, high glucosinolate broccoli, and water.

In patient tissues, a higher expression of miR30a-3p and a lower expression of Cx43 correlated with malignancy.

Based on the evidence, researchers said, "These findings provide new knowledge and suggest sulforaphane as cotreatment for pancreatic cancer".

Taken altogether, the consequences of these results suggest that the broccoli process the potential anti-pancreatic activity, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Inhibition of miR30a-3p by sulforaphane enhances gap junction intercellular communication in pancreatic cancer by Georgikou C1, Yin L2, Gladkich J3, Xiao X4, Sticht C5, Torre C6, Gretz N7, Gross W8, Schäfer M9, Karakhanova S10, Herr I. (PubMed)

Omega 3 Fatty Acids, A promising Anti Chronic Cerebral Hypoperfusion Remedy

By Kyle J. Norton

Chronic cerebral hypoperfusion is a medical condition associated with the small vessel diseases or atherosclerosis of multiple large vessels found mostly in people who are cognitive normal elderly and patients who have cognitive impairment.

Acute cerebral hypoperfusion has been found to induce neuronal necrosis and infarction, compared to chronic cerebral hypoperfusion that causes the apoptosis of neurons.

A neuron or nerve cell made of a cell body (also called soma), dendrites and an axon, is a cell in the nervous system that carries electrical impulses.

Neurons are core components of the brain, spinal cord and peripheral nerves that play an essential role to process and transmit information.

The function of neurons can be classified into 3 types
* The sensory neurons found within the nervous system that convert external stimuli from the organism's environment into internal electrical impulses. In other words, sensory neurons are activated by sensory input from the environment, including physical input of sound, touch, heat, or light.

*The motor neurons transmit impulses from the spinal cord to skeletal and smooth muscles,. In other words, motor neurons directly control all of the muscle movements.

* The interneurons connect the motor and sensory neurons. In other words, the interneurons transfer signals between sensory and motor neurons.

Neurons are core components of the brain, spinal cord and peripheral nerves that play an essential role to process and transmit information.

Cerebrovascular disease is a common cause of Alzheimer's disease (AD).

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential plant that processes neuroprotective activity researchers examined the effect of gamma-linolenic acid in the rat brain tissues after bilateral common carotid artery occlusion (BCCAO) rat model of chronic cerebral hypoperfusion.

According to the results of the analysis,
* Arachidonic acid (ARA), docosahexaenoic acid (DHA), dihomo-γ-linolenic acid, hydroxyeicosatetraenoic (HETE)-Ala and glycerophosphoethanolamine levels were significantly reduced in the hippocampus and cortex of animals submitted to BCCAO model when compared to control animals.

* Decanoic acid was increased after 30 days of BCCAO model.

Collectively, researchers said, "these findings indicate that lipid dynamics are altered in chronic ischemia-induced by BCCAO in rats and indicate potential biomarkers and pharmacological targets for vascular dementia (VD)".

Taken altogether, omega3 fatty acids may be considered a remedy for the prevention and treatment of chronic cerebral hypoperfusion,, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cerebral Lipid Dynamics in Chronic Cerebral Hypoperfusion Model by DESI-MS Imaging by
Severiano DLR1, Oliveira-Lima OC1, Vasconcelos GA2, Lemes Marques B1, Almeida de Carvalho G1, Freitas EMM1, Xavier CH3, Gomez MV4, Pinheiro ACO5, Gomez RS6, Vaz BG7, Pinto MCX8. (PubMed)

Ashwagandha Inhibits β-amyloid Against the Risk of Alzheimer's disease

By Kyle J. Norton

Amyloid beta (Aβ or Abeta) is the main component of the amyloid plaques that cause the gradual death of neurons, the leading cause of Alzheimer's disease.

Alzheimer's disease is a common form of dementia or neurodegenerative disease found in the elderly.

Alzheimer's disease is a type of dementia correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer.

According to the statistics, the disease is most prevalent in the elderly. Approximately 5.7 million Americans of all ages are living with Alzheimer's. 15.9 million family caregivers provide an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.

 Alzheimer's disease is caused by a combination of genetic, lifestyle and environmental factors that affect the neurons of the brain over time.

However, less 10% of patients with AD are associated with a genetic preposition. Patients with such mutated genes on chromosomes 21, 14, and 1are virtually guaranteed to develop the disease.

More precisely, Alzheimer's disease is caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.

Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal.

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound for the treatment of the neurodegenerative disorder, researchers examined the effects of Withania somnifera (WS) against β-Amyloid (1–42)-induced neuropathogenesis.

According to the tested results, methanol Chloroform (3:1) extract from ashwagandha showed a strong activity against β-amyloid induced toxicity and HIV-1Ba-L (clade B) induced infection in a human neuronal SK-N-MC cell line.

Furthermore, the efficacy of the extracts inhibited β-amyloid induced cytotoxic effects by decreasing the cell growth in SK-N-MC cells.

Moreover, the extracts also protect the spine functioning by decreasing spine density, loss of spines and dendrite diameter, total dendrite and spine area in clade B infected SK-N-MC cells compared to uninfected cells.

Additionally, the MTT cell viability assays and the peroxisome proliferator-activated receptor-γ (PPARγ) levels that regulate adipogenesis, lipid metabolism, cell proliferation, and inflammation also supported the neuroprotective effect of WS root extract against β-amyloid and HIV-1Ba-L (clade B) induced neuro-pathogenesis.

Taken altogether, Ashwagandha may be considered a functional herb for the prevention and treatment of Alzheimer's disease, pending to the result of larger sample size and multicenter study



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Ashwagandha (Withania somnifera) Reverses β-Amyloid1-42Induced Toxicity in Human Neuronal Cells: Implications in HIV-Associated Neurocognitive Disorders (HAND) by Kesava Rao, Venkata Kurapati, Venkata Subba Rao Atluri, Thangavel Samikkannu, and Madhavan P. N. Nair. (Plos One)

Healthy Food Cruciferous Vegetables, the Potential Treatment of Neurological Disorders

By Kyle J. Norton

Neurological disorders are medical conditions characterized by any disorder of the nervous system caused by structural, biochemical or electrical abnormalities.

There are many forms of neurological disorders. The most common types of the disease are neurodegenerative disease, such as Alzheimer's disease (AD) and Parkinson's disease, epilepsy. multiple sclerosis and Migraines.

Back pain associated with the related nerve damage is one of the common complaints in the US that send many patients to seek help from their doctor. Believe it or not, 80% of the US population will experience back pain at some time in their lives.

There is no single cause of neuro-dysfunction. Lifestyle, infections, genetics, and nutrition-related disease, environment, and physical injuries have been found to some major prevalent factors that induce the onset of neurological abnormalities.

According to the Medical press, globally, the burden of neurological disorders (Alzheimer's disease, Parkinson's disease, stroke, epilepsy, etc) has increased substantially over the past 25 years. These may be results of over 25 years of economic expansion that have increased the living standard of billions of people in the Southeast Asian region.

The WHO in the evaluation of neurological disorder wrote, "Neurological disorders contribute to 92 million disability-adjusted life years (DALYs) in 2005 projected to increase to 103 million in 2030 (approximately a 12% increase). While Alzheimer's and other dementias are projected to show a 66% increase from 2005 to 2030".

Where one DALY represents the loss of the equivalent of one year of full health.

Believe it or not, there are more than 600 diseases of the central nervous system, including brain tumors, epilepsy, dementia such as Parkinson's disease and Alzheimer's disease and stroke.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding a potential remedy for the protection of the brain functioning, researchers examined the effects of cruciferous vegetables are a key part of the arsenal of nutrition-based approaches for reducing the risks of neurological disorders.

According to the search of related articles, in animal model systems, cruciferous vegetables exerted the protective activity against neurodegenerative disorders like Alzheimer's and Parkinson's diseases.

In chemical analysis, the efficacy of crucifers in the inhibition of the onset and progression of neurological disorders was attributed to its most abundant bioactive compound the isothiocyanates, particularly sulforaphane.

Based on the findings, researchers said, "There is great promise for the regular use of cruciferous vegetables or supplements containing standardized levels of bioactive in the treatment and prevention of neurologic disorders".

And, " Many clinical and animal studies are underway, and the evidence is building to support this strategy".

Taken altogether, cruciferous vegetables may be considered functional remedies for the prevention of neurological disorders, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Crucifers and related vegetables and supplements for neurologic disorders: what is the evidence? by Panjwani AA1,2, Liu H1,3, Fahey JW. (PubMed)

Beta-Sitosterol A Potential Treatment of Menopausal Symptoms

By Kyle J. Norton

Menopause is a condition in which a woman is in the transition stage of permanent cessation of the ovaries functions in egg production because of less production of estrogen and progesterone, signaling the end of the reproductive phase a woman's life.

In menopause, menstruation has become irregular and slowly stop overtime, but in some women, menstrual flow comes to a sudden halt.

Some researchers suggested that you officially enter the stage of menopause if you have gone 12 months without a menstrual period.

Compared to menopause, peri-menopause is a condition in which women experience the irregular menstrual cycle due to the hormonal decline gradually, including shorter, longer, heavy, light periods and some menopause symptoms.

Perimenopause, in fact, is a transition stage to menopause, and the length of this transition can be 3-10 years or longer. Once you have no menstrual period in 12 consecutive months, you have officially entered 12 months of menopause already.

Women enter the menopause stage differently, but the average age is 51 in the United States.

Women with ovarian failure or removed may experience symptoms of menopause at early age 38.

Symptoms of menopause are the result of the gradually reduced production of estrogen and progesterone, the 2 most abundant hormone in the childbearing age women.

Most women in the Western world experience symptoms of hot flashes and emotional symptoms of menopause may disrupt your sleep, lower your energy or affect emotional health.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the treatment of menopausal symptoms, researchers elucidated the biological activities of Pueraria lobata (PL) on menopause-related metabolic diseases.

According to the results of ovariectomized (OVX) rats as a postmenopausal model that were administered PL at different doses (50, 100, and 200 mg/kg),

* The decreased uterine weights and PPAR-γ (peroxisome proliferator-activated receptor-gamma) mRNA expression in the thigh muscle found in menopausal females in the ovariectomized (OVX) rats were significantly recovered after PL administration.

* Furthermore, PL also significantly alleviated OVX-induced increases in total cholesterol, triglyceride, alanine aminotransferase (ALT/GPT), and aspartate aminotransferase (AST/GOT) levels.

More precisely, the efficacy of Pueraria lobata (PL) on menopause-related metabolic diseases was attributed to four potential active compounds, including beta-sitosterol.

In other words, the chemical compounds exerted a strong activity against multiple targets among female sex hormone-related pathways, including the estrogen signaling pathways, progesterone-mediated oocyte maturation, oxytocin signaling pathways, and prolactin signaling pathways.

Based on the findings, researchers said, "PL improved various indicators associated with lipid metabolism in the postmenopausal animal model".

Beta-Sitosterol may be considered a remedy for the prevention and treatment of menopausal symptoms, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Investigating the Systems-Level Effect of Pueraria lobata for Menopause-Related Metabolic Diseases Using an Ovariectomized Rat Model and Network Pharmacological Analysis by Oh JH1, Baek SE2, Lee WY1, Baek JY3,4, Trinh TA3, Park DH3, Lee HL5, Kang KS3, Kim CE1, Yoo JE. (PubMed)