Wednesday, 8 July 2020

Dandelion(Taraxacum officinale), the Antimicrobial Herbal Remedy

By Kyle J. Norton

Microorganisms, or microbes, are a class of microscopic organisms, including the single-celled form.
Microbial infection is a disease caused by microorganisms, including viruses, bacteria, fungi, or parasites.

Antimicrobial activity is an action that kills microorganisms or stops their growth. In humans, these actions are carried out daily by the immune system.

Infection is a processive condition caused by the battle of the invasion of microorganisms and the host immune white blood cells. Microorganism during the battle might produce toxins which can lead to the initiation of infection-related transmissible disease or communicable disease.

In acute infections, the systematic immune system responds properly to the invasive pathogen, leading to a brief battle after which the immune system is always victorious.

However, chronic infections occur when the immune cannot kill off the invasive stimuli in the acute phase of infection, leading to chronic infectious diseases.

Microbial infection includes 4 different stages
* Stage 1 or incubation stage
In stage 1, harmful microorganisms after successfully entering the host start to incubate on the specific site by the multiplying organism to reach a population, leading to an early stage of symptoms.

* Stage 2 or prodromal stage
After successfully multiplying, the organisms start to show symptoms of illness, depending on the location of the infection.

* Stage 3 or acute stage
The numbers of microorganisms have grown exponentially, leading to very pronounced symptoms, also depending on the location and organ being infected.

* Stage 4 or convalescence stage is the recovery stage. The microorganism starts to decrease or are wiped out from the host.

Most cases of recovery infection are the result of the use of antibiotics. The length of the 4 stages of microbial infection can be vary depending on the host immune system.

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the antimicrobial effects of crude and dialyzed extracts from the dandelion root (Taraxacum officinale) on Gram-positive and Gram-negative bacterial strains.

According to the tested differentiation, 
* The methanol hydrophobic crude extract (DRE3) demonstrated the strongest inhibition of microbial growth against Staphylococcus aureus, methicillin-resistant S. aureus and Bacillus cereus strains.
* Normal phase (NP) fractionation of DRE3 (NPF4 and NPF5) enhanced antimicrobial activity.

* Furthermore, further NP fractionation of NPF4 resulted in two fractions (NPF403 and NPF406) with increased antimicrobial activity.

Based on the findings, researchers said, " the antimicrobial efficacy of dandelion root extracts demonstrated in this study support the use of the dandelion root as a source of natural antimicrobial compounds".

Taken altogether, Dandelion may be considered a remedy for the treatment of infectious diseases caused by bacteria, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Characterisation of antimicrobial extracts from dandelion root (Taraxacum officinale) using LC-SPE-NMR by Kenny O1, Brunton NP, Walsh D, Hewage CM, McLoughlin P, Smyth TJ. (PubMed)

Tuesday, 7 July 2020

Common Fig or Fig (Ficus carica) Inhibits the Cervical Cancer Risk in Vitro

By Kyle J. Norton

The cervix is the lower part of the uterus that opens at the top of the vagina. The cervix acts as a transition area for vaginal lining (squamous epithelium) to the uterus type (columnar epithelium) which hosts the development of the fetus.

Cervical cancer is a malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cell DNA.

Precervical cancer is the early stage of abnormal cell changes in the cervical tissues, if left untreated, it can develop into true invasive cervical cancer.

A vaccine, Gardasil used to prevent pre-cervical cancer from the infection of two types of HPV was approved by the U.S. Food and Drug Administration in 2006. It is for your benefit to take this vaccine if you are sexually active with several partners.

Researchers do not know what causes cervical cancer. Neither they can explain that women with the same health condition, family history, some are susceptible to the disease while others do not.

Most cases of cervical cancer start in the cell on the surface of the inner lining tissue of the cervix. At this stage, most women with cervical cancer do not experience any symptoms.

At the advanced stage, invasive cancer can induce symptoms of abnormal bleeding, pain during sexual intercourse, increased vaginal discharge. If the tumor has suppressed the nearby nerve cells, cervical cancer can also cause localized severe pain.

According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer were diagnosed with the death of 4,020 patients.

The 5-year survival rate for women with invasive cervical cancer is 92%. and approximately, 46% of women with cervical cancer are diagnosed at an early stage.

Epidemiological also suggested that HPV infection, sexual activity, smoking, giving birth many times. Infection with the human immunodeficiency virus (HIV, history of sexually transmitted infections (STIs) and long-term use of oral contraceptives are some prevalent risk factors of cervical cancer.

Fig is a species of F. Carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.

On finding natural compounds for the treatment of malignant tumors, researchers examined the latex of fig fruit (Ficus carica) on cervical cancer cell lines CaSki and HeLa positive for HPV type 16 and 18, caused by high-risk human papillomaviruses (HPVs).

Based on the experimental results, fig latex inhibits the rapid growth and invasion properties that cause HPV-positive cervical cancer bt alternating the cell DNA.

Furthermore, fig latex also inhibited the substantially downregulated the expression of p16, a tumors suppressor and HPV oncoproteins E6, E7 associated with the turnover of tumors suppressive genes in the tested cell line.

Based on the findings, researchers said, " Ficus carica latex has the potential to be used in the development of therapeutic modalities for the possible treatment, cure, and prevention of HPV related cervical cancer".


Taken altogether, common fig or fig (Ficus carica)  may be considered a remedy for the prevention and treatment of cervical cancer, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(10) Biological activities of Ficus carica latex for potential therapeutics in Human Papillomavirus (HPV) related cervical cancers by Ghanbari A1, Le Gresley A2, Naughton D2, Kuhnert N3, Sirbu D3, Ashrafi GH4. (Research Gate)

Monday, 6 July 2020

Tocopherols Kills Oral Cancer Cells in Vitro

By Kyle J. Norton

Mouth/oral cancer is a medical condition associated with the irregular cell growth on the tissues of the mouth caused by genetic alteration of the cell DNA.

Most cases of mouth cancer start in the flat, thin cells (squamous cells) of the inner lining tissue that lines the lips and the inside of the mouth.

According to the statistics provided by the American cancer society, in 2018, approximately, over 50,000 people will get oral cavity or oropharyngeal cancer. An estimated over 10,000 people will die because of these cancers in the United States.

The exact causes of mouth cancer are unknown. However, the increase in age, gender, exposure to radioactive, long-term use of tobacco use and excessive alcohol drinking, viral infection and genetic mutation are the most common prevalent risk factors found in people with mouth cancer.

The grades of oral cancer are depending on the tendency of spreading. Low-grade cancers usually grow more slowly and are less likely to spread while high-grade cancer indicates otherwise.

Stages
1. Stage O
Benign tumor
2. Stage I
The cancer is < 2 cm in size (about 1 inch), with no lymph nodes spreading found in the area.
3. Stage II
The cancer is ≥ 2 cm in size, but < 4 cm (less than 2 inches), with no lymph nodes spreading found in the area.4. Stage III

The cancer is ≥ cm in size or any size with only one lymph node on the same side of the neck as of cancer. The cancerous node is ≤ 3 cm (about one inch).
5. Stage IV
Cancer has spread to tissues around the lip and oral cavity with lymph nodes in the area may or may be infected. The cancer of any size and has spread to more than one lymph node on the same side of the neck or lymph nodes on one or both sides of the neck, or to any lymph node that measures ≥ 6 cm (over 2 inches) in size or to distant parts of the body.

Tocopherols are phytochemicals of which many have vitamin E activity, belongings to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of chronic diseases associated with inflammation, researchers examined the effects of α-tocopherol on the oral squamous carcinoma cells ORL-48.

According to the experimental results,
* In vitro study, α-tocopherol exhibited effective antitumor activity on ORL-48 at 2.5 ± 0.42 µg/mL.

* Although Cisplatin exhibited stronger activity at 1.0 ± 0.15 µg/mL, compared to α-tocopherol which exhibited cytotoxicity on normal human epidermal keratinocytes at very low concentration (<0.1 µg/mL).

* Despite the lower potency of α-tocopherol, signs of apoptosis such as the shrinkage of cells and appearance of apoptotic bodies were observed much earlier than cisplatin in time-lapse microscopy. 

* Both applications increased the number of cell accumulation in the G0/G1 phase with ultrastructural changes of the cellular structures verified the apoptotic mode of cell death by both agents.

Based on the findings, researchers said, " Both cisplatin and α-tocopherol displayed cell cycle arrest at the Sub G0 phase. α-tocopherol thus showed potential as an antitumor agent for the treatment of oral cancer and merits further research".

Taken altogether, tocopherols may be considered a supplement for the prevention and treatment of oral cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Vitamin E (α-Tocopherol) Exhibits Antitumour Activity on Oral Squamous Carcinoma Cells ORL-48 by Zulkapli R1,2, Abdul Razak F1, Zain RB. (PubMed)

Sunday, 5 July 2020

Omega -3 Fatty Acids Inhibits the Risk Of Biliary Tract Cancer

By Kyle J. Norton

The digestive system consists of the gastrointestinal tract and other parts of the accessory organs of digestion including the tongue, salivary glands, pancreas, liver, and gallbladder, involved in the function of breaking down food into smaller and smaller components then absorbed before passing them as nutrients and fluids to the body.

Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.

Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.

However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite and fatigue but also localized symptoms depending on the affected tissues and organs.

Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.

According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.

Gastrointestinal (GI) cancer is a group of cancers, affecting the digestive system, including esophagus, gallbladder & biliary tract, liver, pancreas, stomach, small intestine, bowel, and anus

Bile duct, the tube-like structure carries bile to the intestine for food digestion secreted by the liver through the common bile duct.

Bile duct cancer is a condition caused by the malignant cells originated from the cells in the duct. the condition is more likely to affects people between the age of 50 - 70 with an annual incident rate of fewer than 2 cases per 100,000 in the Western world.

Most common symptoms of biliary tract cancer are
* Abdominal pain
Due to the enlarged tumor that has blocked the flow of bile.
&Jaundice
Any blockage of the flow of bile will reduce liver function in waste procession, in this case, it is the death of blood cells.
* Weight loss
Weight loss is a general cause of cancer
* Itching
Due to abnormal function in toxins procession.
* Fever
As a result of infection or inflammation
* Stool or urine color change
Due to bile flows back to the liver.
* Enlarged liver
May be caused by a backflow of bile
* Nausea and vomiting
They are the general symptoms of cancer
* Loss of appetite
Another general symptom of cancer

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of cancers, researchers examined the omega 3 fatty acid effects in the improvement of the completion rate of adjuvant chemotherapy in patients with BTC.

According to the tested analysis from the previous studies
Without Omega 3 fatty acids added to the chemo treatment
* Multimodal treatment prolongs the survival of patients with biliary tract cancer (BTC).

* Chemotherapy choices for this disease are few, and completing each chemotherapy session is important.

* Adjuvant chemotherapy has been attempted for BTC, but has only had a 75% completion rate.

* Induced body weight loss and cholangitis are reasons for the interruption of chemotherapy.

With Omega 3 fatty acid added to the chemotherapy

* Nutritional intervention with omega-3 fatty acids maintained body weight and improved the completion rate for chemotherapy.

* Omega-3 fatty acids have an anti-inflammatory effect against the onset of symptoms of chemo treatment

* Omega-3 fatty acids would improve the completion rate of adjuvant chemotherapy in patients with BTC.

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered adjunct therapy for the treatment of biliary tract cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effectiveness of omega-3 fatty acid administration on completion rate of adjuvant chemotherapy for biliary tract cancer: study protocol for a single-centre, open-label, single-arm, historically controlled study by Ueno K1, Ajiki T, Tsugawa D2, Akita M2, Hashimoto Y2, Awazu M, Mukubo H2, Komatsu S, Kuramitsu K, Terai S, Tanaka M2, Toyama H2, Kido M, Fukumoto T. (PubMed)

Friday, 3 July 2020

Cranberry, A Gastric Protective Remedy

By Kyle J. Norton

The stomach formed part of the digestive system that receives food from the esophagus before passing them to the small intestine is a muscular organ located on the left side of the upper abdomen.

The stomach is the first line of food digestive by secreting acid and enzymes.

Gastric protection is the process or action that protects the stomach by increasing the production of gastric (stomach) mucus with an aim to protect the stomach wall.

The most common diseases associated with the stomach are
*Gastric/Stomach cancer is a medical and chronic condition caused by the cell growth irregularly and disorderly in the cells on the surface of the inner lining tissue before penetrating deeper into other layers of the stomach to form a tumor, due to the alternation of DNA.

Gastritis
Gastritis is a group of conditions associated with the inflammation of the lining of the stomach caused by infection of the bacterium, leading stomach ulcers developing.

* A stomach ulcer is an open sore in the lining of the stomach. In most cases, it is a result of bacterial infection that leads to the erosion of the gastric lining by stomach acid.

* Atrophic gastritis is a condition of loss of gastric glandular cells caused by long-term inflammation of the stomach mucous membrane (mucosa).

Loss of the gastric glandular cells in the long term eventually is replaced by intestinal and fibrous tissues.

* Gastric ulcers
Gastric ulcer, a type of peptic ulcer is defined as a condition of localized tissue erosion in the lining of the stomach.

Most cases of stomach diseases are associated with infection, such as with Helicobacter pylori. and the most common symptoms of stomach diseases are nausea, bloating, diarrhea and abdominal pain.


Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the protection of the stomach, researchers investigated the effects of drinking cranberry juice on H. pylori infection.

According to the review of selected studies, cranberry juice showed significant activity in preventing H. pylori adhesion in vitro to the human gastric mucosa.

In Vivo, cranberry juice fed to mice infected with H. pylori, 80% were cured 24 h following treatment, with an eradication rate of 20%, 4 wk post-treatment.

Moreover, cranberries in the combination with traditional anti-H. pylori antibiotics such as metronidazole and clarithromycin were proven proved effective in improving eradication rates and suppressing infections in endemic populations.

Additionally, the inhibitory action of cranberries against H. pylori was attributed to its effect on the inhibition of adhesion, biofilm formation blocking.

Taken altogether, cranberry combined with conventional medicines may be considered a gastric protective remedy for the management of obesity, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Non-pharmacological treatment of Helicobacter pylori by Haim Shmuely, Noam Domniz, and Jacob Yahav. (PMC)

Thursday, 2 July 2020

Common Fig or Fig (Ficus carica) Processes Anti Stomach/Gastric Cancer Activity in Vitro

By Kyle J. Norton

Cancer is a class of chronic diseases associated with irregular cell growth in the tissues of the affected organ.


The stomach located between the esophagus and the small intestine is a muscular, hollow and important organ of the digestive tract.

The stomach plays a critical role to assist the digestive system in digesting foods by secreting acid and enzymes.

Stomach cancer is a condition of abnormal growth of the mucus-producing cells of the inside lining of the stomach caused by the alternation of the cell DNA. Adenocarcinoma is the most common type of stomach cancer.

According to the statistics, most cases of gastric/stomach cancer are found in older people. The average age of people when they are diagnosed is 68. The risk of developing gastric/stomach cancer in a man lifetime is about 1 in 95.

According to the American Cancer Society, in 2018, approximately 26,240 new cases of stomach cancer were diagnosed, including 6,520 men and 9,720 women, and gastric cancer caused the death of 10,800 people including 6,510 men and 4,290 women.

The 5 years survival rate of localized gastric cancer is 67%, compared to the advanced stage of only 31%.

Most patients with stomach cancer in the early stage are asymptomatic.

However, at the later stage, patients may experience symptoms of pain and/or discomfort in the stomach area, mild ache in the upper part of the body, difficulty swallowing, feeling full or bloated after a small mealy, and vomiting blood or having blood in the stool accompanied by general symptoms shared by other types of cancer, including unintentional weight loss, loss of energy, tiredness, nausea, and vomiting and loss of appetite.

Fig is a species of F. Carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.

On finding natural compounds for the treatment of malignant tumors researchers examined the effect of fig tree latex (Ficus carica) on stomach cancer line.

The study included different doses of fig tree latex that were incubated with the stomach cancer cell line and the peripheral blood mononuclear cells in a period of 72 hours.
According to the tested differentiation,
* Fig tree latex showed a significant anti-cancer activity by blocking the proliferation of cancer cell lines through its cytotoxicity without causing harm to human normal cells.

* Furthermore, the stomach cancer cell line was more sensitive to Ficus carica latex than normal cells.

Moreover, Ficus carica latex induced cancer cell death might be attributed to the presence of proteolytic enzymes, which has been found to be involved in the degradation of the cancer cells extracellular matrix and inhibited cancer invasion and metastasis.

Taken altogether, common fig or fig (Ficus carica)  may be considered a remedy for the prevention and treatment of gastric cancer, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line by Hashemi SA1, Abediankenari S, Ghasemi M, Azadbakht M, Yousefzadeh Y, Dehpour AA. (PubMed)

Wednesday, 1 July 2020

Tocopherols Inhibits the Initiation, Progression and Treatment of Lung Cancer

By Kyle J. Norton

The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream to nourish the body cells' need and exhaling carbon dioxide from the bloodstream.

Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. The most common form of primary lung cancers is derived from epithelial cells.

In the US, lung cancer is the leading cause of cancer deaths, including 88,329 men and 70,354 women, according to the 2007 statistic.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

Researchers do not the exact causes of lung cancer. 

Genetic mutation inherited from the parents is a result of an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to increase a person's chance of developing lung cancer.

However, not all people who carry mutated lung cancer genes will develop lung cancer.

On the cigarette smoking in risk of lung cancer, researchers believe cigarette containing high amount of cancer-causing substances (carcinogens), when inhaled, the cigarette smoke carried the chemical toxins to the lung cell directly, and prolonged periods exposed to such chemicals can alternate lung cell DNA, leading to the early onset of lung cancer.

Some researchers suggested genetic mutation and long-term cigarette smoking are 2 major risk factors associated with the alternative of lung cell DNA.

Truly, according to the statistic, approximately 8% of lung cancers are inherited or occur as a result of a genetic predisposition.

On finding a potential phytochemical for the treatment of lung diseases, researchers examined the growth inhibitory effect of a gamma-tocopherol-enriched tocopherol mixture (gammaTmT) against CL13 murine lung cancer cells grown in culture and as subcutaneous tumors in A/J mice.

According to the analysis,
* GammaTmT had no effect after 2 days and weakly inhibited the growth of CL13 in culture after 5 days (28% growth inhibition at 80 microM).

* Furthermore, dietary treatment at doses of 0.1 and 0.3% gammaTmT for 50 days inhibited the growth of CL13 tumors in A/J mice by 53.9 and 80.5%, respectively.

* According to the histopathological analysis, gammaTmT revealed an increase in tumor necrosis compared to control tumors.

* Moreover, dietary treatment with gammaTmT dose-dependently increased gamma- (10.0-37.6-fold) and delta-tocopherol (8.9-26.7-fold) in the tumors of treated mice compared to controls.

* Additionally, dietary treatment with gammaTmT also increased plasma gamma- (5.4-6.7-fold) and delta-tocopherol (5.5-7-fold). Whereas others have demonstrated the cancer-preventive activity of gammaTmT against mammary and colon cancer, this is the first report of growth inhibitory activity against lung cancer.

Taken altogether, tocopherols may be considered a supplement for reducing the risk of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tocopherols and tocotrienols as anticancer treatment for lung cancer: future nutrition by Zarogoulidis P1, Cheva A, Zarampouka K, Huang H, Li C, Huang Y, Katsikogiannis N, Zarogoulidis K. (PubMed)
(2) Inhibition of lung cancer growth in mice by dietary mixed tocopherols by Lambert JD1, Lu G, Lee MJ, Hu J, Ju J, Yang CS. (PubMed)