Herbal Angelica Improves Impairment of Testosterone Synthesis Induced Infertility

By Kyle J. Norton

Testosterone is a male hormone. The hormone besides promoting libido it has other important functions such as maintaining muscle mass and forming bone and regulating heart muscle and cholesterol.

The Hormone also helps to improve the oxygen levels throughout the body as well as controlling blood glucose and strengthening the immune system.

However, as men age, the pituitary gland produces less free testosterone while more free testosterone is being converted to estrogen which results in many health problems.

Testosterone is synthesized primarily in Leydig cells stimulated by the pituitary gland to release FSH and LH.

In other words, when the levels of testosterone are low, testosterone is synthesized induced by gonadotropin-releasing hormone (GnRH) that is released by the hypothalamus.

Symptoms associated with  testosterone deficiency are

* Decreased sexual function
As we mentioned in the last article, starting at age 40 levels of testosterone start to diminish. The levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to dihydro-testosterones DHT thus triggering low levels of testosterone resulting in sexual dysfunction.

* Loss of bone density
The brain and bone are the important issues that have the primary effect of testosterone are by way of aromatization to 17² estradiol in the bones. 17²-estradiol accelerates the maturation of cartilage into bone, leading to the closure of the epiphyses (a rounded end of a long bone) and a conclusion of growth.

* Loss of muscle mass
Testosterone effects can be classified as anabolic effects that include growth of muscle mass and strength, increased bone density and strength, and stimulation of height growth and bone maturation. Testosterone effects can also be classified by the age of usual occurrence.

* Memory loss
Low levels of testosterone allow beta-amyloid, a toxic peptide to accumulate in certain regions of the brain causing memory loss.

* Abdominal fat
Fat cells create aromatase enzymes that contribute to fat build up and low levels of testosterone which allows the forming of abdominal fat that produces more aromatase enzymes resulting in more formation of estrogen. It also causes insulin resistance by increasing fat around the stomach/waist area and fat mass.

Impairment of testosterone synthesis is a condition associated with the testis impaired by the cryptorchid state,

On finding a natural ingredient for the prevention and treatment of cancers, scientists examined the Chinese angelica polysaccharide (CAP), the main effective ingredient of angelica sinensis anti-inflammatory and anti-apoptotic effects.

Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a potential compound for the treatment of male infertility, researchers examined the protective effect of a mixture of 2 herbal extracts, KH-465, which consisted of Epimedium koreanum Nakai and Angelica Gigas Nakai, on spermatogenesis in a luteinizing hormone-releasing hormone (LHRH) agonist-induced rat model of male infertility.

The study included 75 12-week-old male Sprague-Dawley rats that were randomly divided into 5 groups, containing 15 rats each: a normal control group that received no treatment and 4 experimental groups (I, II, III, and IV) in which an LHRH agonist was administered for 4 weeks to induce spermatogenic failure. Group I received distilled water, and groups II, III, and IV received 200 mg/kg/day of KH-465, 400 mg/kg/day KH-465, and depo-testosterone for 4 weeks, respectively.

According to the results of differentiation,
* There are no significant changes in Body, testis, and epididymis weight among the control and experimental groups.
* Treatment with KH-465 increased sperm count and motility. 

* Serum hormone levels of T, free T, and FSH were not significantly different in the experimental groups, while the LH level was higher than in the LHRH agonist-induced control group, but not to a significant extent.

* Levels of SOD were higher and 8-OHdG were lower in the groups that received KH-465 than in the LHRH agonist-induced control group.

Based on the results, researchers suggest, "Our results suggest that KH-465 increased sperm production via reducing oxidative stress and had a positive effect in a male infertility model".

Taken altogether, herbal Angelica alone or in combination with another herbal remedy may be used for the treatment of male infertility, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Restoration of Spermatogenesis Using a New Combined Herbal Formula of Epimedium koreanum Nakai and Angelica gigas Nakai in an Luteinizing Hormone-Releasing Hormone Agonist-Induced Rat Model of Male Infertility by Hyun Jun Park, Yean Kyoung Koo, and Nam Cheol Par. (PMC)

Herbal Devil's Club Processes Anti-Inflammatory Property

By Kyle J. Norton

Anti-inflammation is a process that inhibits the pro-inflammatory cytokines without affecting the immune system activity against pathogens.

Acute inflammation is a natural response of the immune system to protect the human body against harmful stimuli and pathogens.

Acute information is the first phase of injection. At this phase, after sensing the body injury by the central nervous system, the immune first line of defense stimulates the production of blood platelets to the cover the site of damage and pro-inflammatory to kill off pathogens that try to enter the body through the wound or damaged tissue.

Acute inflammation usually receded after a few days or weeks, depending on the size and damage. However, if all pathogens were not eradicated after 3 to 8 weeks, the immune system will compromise, leading to chronic low-grade inflammation, a leading cause of chronic illness.

The most common symptoms of acute inflammation occurred with a short period of time such as hours is pain, redness, immobility, swelling, and heat.

Conventionally, depending on the types of acute inflammation, non-steroidal anti-inflammatory drugs (NSAIDs) may be prescribed to alleviate the pain by counteracting an enzyme that contributes to inflammation.

Chronic inflammation is a low-grade inflammation caused by the inability of the immune system to eliminate the invasive pathogens that occurred in the acute phase of infection.

Any inflammation that lasts more than 8 weeks is considered chronic inflammation.

Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.

In the US, chronic inflammatory diseases affect more than 50 million Americans each year.

Devil's Club is a large shrub, genus Oplopanax, belonging to the family Aralioideae, native to the cool moist forests of western North America. 

The herb has been used in traditional and herbal medicine as Adaptogen, Antipyretic, Pain Reliever, Antitussive, Antibacterial agent and to treat Arthritis, Diabetes, Colds, Cough, Sore throat, Chest congestion, Stomach pain, Constipation, Gall stones, Influenza, Cancer, etc.

On finding a potential compound for the treatment of chronic inflammatory diseases, scientists examined the antioxidative stress activity of the ethanolic extracts of the devil's club (Oplopanax horridus) leaves, stems, and roots.

Based on the chemical differentiation, 

* The leaf extract had higher total phenolic and flavonoid contents and anti-oxidative activity (radical scavenging, reducing power, and inhibition of lipid oxidation) compared to the root and stem extracts.

* The leaf extract also had anti-inflammatory effects against the activation of proteins associated with the production of pro-inflammatory cytokines, such as lipopolysaccharide (LPS)-induced nitric oxide (NO; 71.0% at 50 μg/mL), tumor necrosis factor (TNF)-α (87.6% at 100 μg/mL), and interleukin (IL)-6 (36.2% at 100 μg/mL) in the murine RAW 264.7 macrophages.

* Furthermore, LPS-induced inducible nitric oxide synthase (iNOS) expression was also decreased by the leaf extract at the concentration of IC50=24.4 μg/mL.

* The major compounds that exert the aforementioned inhibition was attributed to the expression of gallic acid, protocatechuic acid, chlorogenic acid, and maltol.

Collectively, researchers wrote, " leaf extract could be utilized as a functional food material because of its anti-oxidative and anti-inflammatory activities".

Taken altogether, coltsfoot may be considered a remedy for the protection of inflammatory diseases induced by oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-oxidative and anti-inflammatory activities of devil's club (Oplopanax horridus) leaves by Jang M1,2, Lee YC1, Hong HD1, Rhee YK1, Lim TG1, Kim KT1, Chen F3, Kim HJ4, Cho CW. (PubMed)

Omega-3 Fatty Acids Has NO Effects on Chronic Kidney Diseases

By Kyle J. Norton

Kidneys formed part of the secretory system, are to bean-shaped organs located below the rib cage, one on each side of your spine with a function to filter out blood and remove waste through urinary secretion.

The kidney also plays a critical in maintaining the levels of fluids in the body, by removing extra fluids to make urine.

Furthermore, the kidney also regulates electrolytes, blood pressure, maintains acid-base balance, produces hormone calcitriol, renin, and erythropoietin.

Kidney diseases are a class of medical conditions associated with reduced function of the kidney, in cases, complete loss of kidney function such as kidney failure.

Chronic kidney disease, also known as chronic kidney failure, is a condition of a gradual loss of kidney function.

According to the observation of patients data associated with the diseases, diabetes and high blood pressure are responsible for up to two-thirds of the cases. 

According to the statistic, approximately, 30 million American adults have chronic kidney disease, and a large percentage of these people aren't aware of it. 1 in 3 American adults is at risk for kidney disease.

In other words, approximately 14 percent of the US population suffer some forms of chronic kidney disease (CKD), including 661,000 cases of kidney failure.

Believe it or not, almost half of the individuals with CKD also have diabetes and/or self-reported cardiovascular disease (CVD).

Diabetes is a medical condition caused by long-term abnormally high blood glucose, leading to the damage of other tissue and organs, including the kidneys.

Another cause of chronic kidney disease is kidney disease. Early diagnosis of chronic kidney disease can often keep chronic kidney disease from getting worse.

Late diagnosis of chronic kidney disease may eventually lead to kidney failure, leading to dialysis or a kidney transplant to maintain life.
 

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of kidney, researchers evaluated the effects of the anti-inflammatory effect of omega-3 fatty acids on patients with chronic kidney disease(CKD).

By searching the medical literature on the database from inception to August 2016, including randomized controlled trials (RCTs) derived from multiple databases, and the effect of omega-3 fatty acids supplementation compared to control cohorts, researchers identified a total of 12 RCTs involving 487 patients were included in the meta-analysis.

Among 254 patients received omega-3 fatty acids and 233 patients served as controls who received placebo, there is
* There is no statistical significance in serum levels of C-reactive protein (CRP) (SMD, -0.20; 95% CI, -0.44 to 0.05; P = 0.11),

* The levels of pro-inflammatory cytokine IL-6 associated with the CKD showed insignificant change in both omega 3 and control groups.

* Additionally, chronic kidney disease (CKD) in the constitution of chronic inflammation through the expression of elevated levels of tumor necrosis factor-alpha (TNF-α) also showed insignificant changes in both groups.

Based on the findings, researchers suggested, "there is insufficient evidence to conclude the benefit of omega-3 fatty acids oral supplementation in reducing serum levels of CRP, IL-6, and TNF-α in patients with CKD".

In other words, omega-3 fatty acids may not be used for reducing complications of patients with CKD, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of Omega-3 Fatty Acids on Markers of Inflammation in Patients With Chronic Kidney Disease: A Controversial Issue by Hu C1, Yang M1, Zhu X1, Gao P1, Yang S1,2, Han Y1, Chen X1, Xiao L1, Yuan S1, Liu F1, Kanwar YS3,4, Sun L. (PubMed)
(2) Omega-3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease by Tam KW1, Wu MY, Siddiqui FJ, Chan ES, Zhu Y, Jafar TH. (PubMed)

Herbal Ashwagandha Protects the Neuron Against the Onset of Amyotrophic Lateral Sclerosis in Vivo

By Kyle J. Norton

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a type of dementia that causes the death of neurons controlling voluntary muscles.


Dementia is a condition of neurodegeneration syndrome among elders, affecting memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgment. Over 47 million of the worldwide population are affected by the disease, mostly in the West.

Free radicals have been found to induce Lou Gehrig's disease. Researchers found that glutamate in the synapses enhances the production of free radicals(77) only in motor nerve cells but spare other nerve cells. such as cells control senses and other body functions, causing disruption of astrocytes in regulated glutamate levels.

Maintaining a balanced ratio of antioxidant and free radicals is essential for our body to perform a daily physiological function properly.

Truly, if our body is overwhelmed by overexpression of free radicals, it will be weakened by oxidative stress, causing adversely altered lipids, proteins, and DNA that can trigger a number of human diseases(a), including amyotrophic lateral sclerosis.

Free radicals are unstable molecules that contain at least an unpaired electron with function as oxidants or reductants by donating an electron to or accept an electron from other molecules to exhibit chain and domino's effects.

The most common oxygen-containing free radicals found epidemiologically in induced chronic diseases, including hydroxyl radical, superoxide anion radical, hydrogen peroxide, oxygen singlet, hypochlorite, nitric oxide radical, and peroxynitrite radicals.

Antioxidants have been found to reduces the risk of Lou Gehrig's disease by inhibiting the overexpression of free radicals, including
* Vitamin B12 (methylcobalamin)
High doses of vitamin B12 as an antioxidant have shown to improve or slow muscle wasting in the later stages of patients with ALS disease(78)(79).

* Vitamin E
Vitamin E protected against cell membranes from lipid peroxidation damage(80) in reducing the risk of breakdown of the cell membrane cause of ALS(81).

* Superoxide dismutase enzyme
Mutations in the superoxide dismutase enzyme can increase the risk ALS(82) in catalyzing the dismutation of superoxide into oxygen and hydrogen peroxide(83).

* Cerebral cortex
Oxidative stress and DNA alternation triggered neuron damage(84) were found in elevated levels in mice with ALS(85).

* Amino acids
Diet high in amino acids as antioxidants have shown some promising effect in treating ALS(86)(87).

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

In the urgency to discover a natural ingredient for the treatment of neurological diseases, researchers examined the protective effects of Withania somnifera extract in the SOD1G93A mouse model with amyotrophic lateral sclerosis.

According to the tested analysis, the administration of WS extracts by gavage to mice expressing G93A mutant form of antioxidants superoxide dismutase (SOD1) found in the amyotrophic lateral sclerosis mouse increased longevity, improved motor performance and increased number of motor neurons in the lumbar spinal cord.

In other words, WS extracts inhibited the expression of mutated SOD1 by increasing the cellular chaperons with conformational folding functions.

Furthermore, proteins associated with the induction of pro-inflammatory and pro-apoptosis are also reduced by the injection of WS, through the extracts' immunomodulatory activity.

Moreover, WS extract also induced autophagy at the early stages of the disease, by cleaning out the damaged cells.

Based on the findings, researchers said," WS extracts might constitute promising therapeutics for the treatment of ALS with the involvement of misfolded SOD1".

Taken altogether, Ashwagandha may be considered supplements for the treatment of amyotrophic lateral sclerosis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective effects of Withania somnifera extract in SOD1G93A mouse model of amyotrophic lateral sclerosis by Dutta K1, Patel P1, Julien JP. (PubMed)
(2)The holistic Prevention, Management, and Treatment of Dementia - Free radical causes of Lou Gehrig's disease(Amyotrophic lateral sclerosis) by Kyle J. Norton

Red Cabbage Processes Anti-Bacteria Infection

By Kyle J. Norton

Infectious diseases are a medical condition caused by pathogenic microorganisms, including bacteria, viruses, parasites or fungi.

Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.

In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.

According to the statistic provided by the World Health Organization, 3 infectious diseases were ranked in the top ten causes of death worldwide in 2016.

More precisely, lower respiratory infections, diarrheal diseases, and tuberculosis induced 3.0 million, 1.4 million, and 1.3 million deaths, respectively.

Conventionally, most cases of infectious diseases except those caused by viruses are treated by antibiotics.

Bacteria is a type of biological cell consisted of a single cell with a simple internal structure.

The most common diseases caused by bacteria include strep throat, urinary tract infections, and tuberculosis.

Infection occurs when the bacteria successfully invade the body and start to multiply. Most cases of infectious diseases caused by bacteria are treated with antibiotics.

And, most cases of infectious disease are transmitted by airborne you can get sick if you breathe into the air that carries infectious bacteria in air particles, vector-borne if you are stunk by the insect that the bacteria and vehicle-borne if you are eating food or carrying the materials contaminated by the bacteria.

Most cases of bacterial invasion are met with the first line of immune white blood cells. In the active division of bacteria in the acute phase of infectious, the immune system response activated the production of the proinflammatory cytokine to the site of infection with an aim to kill off all bacteria.

However, if the immune fail to kill off all the bacteria within the 3 - 8 weeks period, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.

On findings a natural wholefood for the prevention of infectious disease, researchers examined the B. oleracea L (red cabbage) anti-microbial activity.

In 22 pathogenic bacteria and fungi, B. oleracea L (red cabbage) demonstrated antibacterial (Methicillin-resistant Staphylococcus aureus, Escherichia coli O157: H7, Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus, and Salmonella enterica serovar Typhimurium) and antifungal (Trichophyton rubrum and Aspergillus terreus) activities at a minimum bactericidal concentration (MBC) and the minimum fungicidal concentration (MFC), respectively.

In Chemical analysis, the potent antimicrobial action from B. oleracea L (red cabbage) was attributed to the rich source of phenolic compounds, anthocyanins.

Based on the results, researchers wrote, "This extract is potentially novel for future antimicrobials, inexpensive, and readily available at a large scale for pharmaceutical companies for further investigation and processing".

Taken altogether, red cabbage may be considered a natural antibiotic, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Inhibition of Growth of Highly Resistant Bacterial and Fungal Pathogens by a Natural Product by Rand R Hafidh,1,2 Ahmed S Abdulamir,2,3 Law Se Vern,4 Fatimah Abu Bakar,4,* Faridah Abas,4 Fatemeh Jahanshiri,5 and Zamberi Sekawi. (PMC)

Herbal Enchinanea Processes Anxiolytic Effects with No Side Effects

By Kyle J. Norton

An anxiolytic is a type of medication, or other intervention, that inhibits anxiety.

Anxiety is a mental disorder characterized by worry about future events and fear of current events.

Some researchers suggested that anxiety disorders are conditions associated with the combination of biological, psychological, and individual factors and the most commonly reported psychiatric conditions and frequently occur as comorbid disorders.

According to the statistic, anxiety disorders are the most common mental illness in the U.S., affecting 40 million adults in the age of 18 and older, or 18.1% of the population every year.

The exact causes of anxiety disorders are debatable. However, a family history of anxiety recent or prolonged exposure to stress, excessive consumption of stimulants such as caffeine or tobacco is associated with the onset of the disorders.

The symptoms of anxiety disorders can be psychological or physical, including difficulty concentrating and sleeping, irritability, persistent stomachaches or diarrhea, sweaty palms, shaking and rapid heartbeat.

People experience anxiety differently. Some people feel a sudden moment of anxiety just a bad feeling, it comes and goes, only lasting a short time. Depending on how people cope with the moments of anxiety, the events can be brief or last a few days.

However, in some persons, if anxiety does not go away, they may require treatment from the related field specialists.

If you are frequently experience symptoms of nervousness, restlessness, or being tense feelings of danger, panic, or dread rapid heart rate rapid breathing, or hyperventilation,..... you may have developed an anxiety disorder.

Echinacea also is known as purple coneflowers, is a flowering plant of the genus Echinacea, belongings to the family Asteraceae, native to eastern and central North America. The herb has been used in traditional and herbal medicine to treat or prevent colds, flu, infections by stimulating the immune function, etc.

On finding a potential phytochemical for the treatment of psychological diseases, researchers examined the anxiolytic effects of a standardized Echinacea extract.

According to the results of a double-blind, placebo-controlled trial with a standardized Echinacea Angustifolia root extract included volunteers who scores above 45 points on the state or on the trait subscale of the State-Trait Anxiety Inventory (STAI) treated with 40 mg Echinacea or with placebo tablets twice daily for 7 days followed by a 3 week-long washout period, 

* State anxiety scores were decreased by approximately 11 points by the end of the treatment period in the Echinacea group, compared to the decrease of around 3-points in the placebo group (p< 0.01).

* The effect maintained over the washout period and the difference from placebo was significant from the 7th day of treatment throughout.

* Furthermore, the changes were less robust with trait anxiety scores, but the preparation performed better than placebo in patients with high baseline anxiety.

* More importantly, neither BDI nor PSS scores were affected by the treatments. Adverse effects were rare and mild, and all were observed in the placebo group.

After talking about other factors into account, researchers said, "These findings suggest that particular Echinacea preparations have significant beneficial effects on anxiety in humans".

Taken altogether, Herbal Enchinanea may be considered adjunct therapies in the treatment of anxiety disorder, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Double-blind placebo controlled trial of the anxiolytic effects of a standardized Echinacea extract by Haller J1,2, Krecsak L3, Zámbori J. (PubMed)

Pinto Beans (Phaseolus) in the Promotion of Gut Microbiota Functioning

By Kyle J. Norton

Gut microbiota or gastrointestinal microbiota, the complex community of microorganisms in our digestive tracts plays a critical role in a variety of metabolic functions, including produced vitamins, synthesized all essential and nonessential amino acids, and carried out biotransformation of bile.

Gut microbiota protects the intestinal structures and functions by attaching to the gut wall against the entry of pathogenic, enteroinvasive bacteria into the epithelial cells.

The gut microbiota plays a vital role in human health, including the key processes of nutrition-enhancing the digestive functioning, lipid, and energy metabolism by inducing the production of short-chain fatty acids (SCFAs), phenolics, and other molecules, and pathogen resistance by promoting the immune function.

In a healthy individual, the levels of gut microbiota are balanced that allow the body to function in an optimal way.

Furthermore, gut microbiota also is found to stimulate the production of some vitamins (B and K), digest certain foods that the stomach and small intestine have not been able to digest, particularly in the combat against the aggression of other bad microorganisms.

In the immune perspective, gut microbiota protects the intestines by alerting the immune response against foreign invasion through specific receptors, induced immune system in the production of the proinflammatory cytokines.

However, the imbalance of digestive gut microbiota has been found to induce a number of diseases, syndromes, and functional aberrations, including inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), and wider systemic manifestations of disease such as obesity, and type 2 diabetes.

Imbalanced gut microbiota is found in obese patients, compared to healthy weight individuals.

On finding a natural ingredient for the prevention and treatment of digestive diseases, scientists examined how legume type and processing method affected digestibility, and subsequent gut microbiota and short-chain fatty acid (SCFA) formation from the pinto bean in vitro digestion.

Pinto bean is also known as common bean, genus Phaseolus and the family Fabaceae. It has a mottled appearance of darker reddish-brown spots on a lighter brownish beige background, thus appearing painted or spotted.

According to the tested analysis of the digestion residues that were fractionated into the soluble and insoluble fiber, and fermented by microbiota from pig feces,

* In vitro, the digestibility was affected significantly by processing method and legume type.

* Autoclaving resulted in higher digestibility.

* The in-vitro digested bean residues caused a rapid pH decrease in the first 12 h during the fermentation with pig feces, and a significant increase in the formation of SCFAs.

More precisely, there is a positive modulation of the gut microbiota by the in-vitro digested bean residues.

Pinto bean exhibited the highest relative abundance in the treatments with germinated bean's soluble residues related to the gut microbiota.

Taken altogether, Pinto beans may improve the balance of the gut microbiota, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Gut microbiota and short chain fatty acid composition as affected by legume type and processing methods as assessed by simulated in vitro digestion assays by Chen Y1, Chang SKC2, Zhang Y3, Hsu CY4, Nannapaneni R. (PubMed)